Pancreatic cancer risk in Peutz-Jeghers syndrome patients: a large cohort study and implications for surveillance

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Medical Genetics

• Publication date

  2012-12-13

• Fields of study

  Medicine

• Identifiers
  DOI 10.1136/jmedgenet-2012-101277PMID 23240097
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• R: A language and environment for statistical computing.

  2014cited by this paper
• Pancreatic cancer.

  2013cited by this paper
• International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer

  2012cited by this paper
• Screening for Pancreatic Cancer in a High-Risk Cohort: An Eight-Year Experience

  2012cited by this paper
• Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4).

  2012cited by this paper
• Frequent detection of pancreatic lesions in asymptomatic high-risk individuals.

  2012cited by this paper
• Familial pancreatic cancer—current knowledge

  2012cited by this paper
• Feasibility and Yield of Screening in Relatives From Familial Pancreatic Cancer Families

  2011cited by this paper
• Magnetic Resonance Imaging Surveillance Detects Early-Stage Pancreatic Cancer in Carriers of a p16-Leiden Mutation

  2011cited by this paper
• High cancer risk and increased mortality in patients with Peutz–Jeghers syndrome

  2011cited by this paper
• Global cancer statistics

  2011cited by this paper
• Magnetic resonance imaging surveillance detects early-stage pancreatic cancer in carriers of a p16-Leiden mutation.

  2011cited by this paper
• European cancer mortality predictions for the year 2011.

  2011cited by this paper
• Pancreatic cancer

  2011cited by this paper
• Peutz–Jeghers syndrome: a systematic review and recommendations for management

  2010cited by this paper
• Pancreatic Cancer Screening in a Prospective Cohort of High-Risk Patients: A Comprehensive Strategy of Imaging and Genetics

  2010cited by this paper
• Is Early Diagnosis of Pancreatic Cancer Fiction? Surveillance of Individuals at High Risk for Pancreatic Cancer

  2010cited by this paper
• Peutz-Jeghers syndrome: a study of long-term surgical morbidity and causes of mortality

  2010cited by this paper
• The Yield of First-Time Endoscopic Ultrasonography in Screening Individuals at a High Risk of Developing Pancreatic Cancer

  2009cited by this paper
• Five years of prospective screening of high-risk individuals from families with familial pancreatic cancer

  2009cited by this paper
• Advances in counselling and surveillance of patients at risk for pancreatic cancer

  2007cited by this paper
• Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome

  2006cited by this paper
• Screening for early pancreatic neoplasia in high-risk individuals: a prospective controlled study.

  2006cited by this paper
• Cancer risks in LKB1 germline mutation carriers

  2006cited by this paper
• Surgical treatment of pancreatic adenocarcinoma; actual survival and prognostic factors in 343 patients.

  2004cited by this paper
• Screening and surveillance for hereditary pancreatic cancer.

  2002cited by this paper
• STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas.

  2001cited by this paper
• Very high risk of cancer in familial Peutz-Jeghers syndrome.

  2000cited by this paper
• Epidemiology of and risk factors for pancreatic cancer.

  1995cited by this paper
• Increased risk of cancer in the Peutz-Jeghers syndrome.

  1987cited by this paper

• Germline genetic profiling utilizing multigene panel testing in Jordanian patients with pancreatic cancer: a comprehensive cancer center experience.

  2026cites this paper
• Recommendations, evidence and sustainability of screening for pancreatic cancer in high-risk individuals.

  2025cites this paper
• Enhancing Early Detection of Pancreatic Cancer in Genetically Predisposed Individuals: Integrating Advanced Imaging Modalities with Emerging Biomarkers and Liquid Biopsy

  2025cites this paper
• Challenges of early detection of pancreatic cancer

  2025cites this paper
• Contemporary insights into the molecular mechanisms of development and genetic susceptibility to pancreatic cancer

  2025cites this paper
• Catching pancreatic cancer early: Are we there yet?

  2025cites this paper
• mTOR pathway diseases: challenges and opportunities from bench to bedside and the mTOR node

  2025cites this paper
• Risk of Pancreatic Cancer in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Germline Variants: A Retrospective Cohort Study

  2025cites this paper
• Peutz-Jeghers Syndrome Presenting With Iron-Deficiency Anaemia and a Giant Colonic Polyp

  2025cites this paper
• Established Cancer Predisposition Genes in Single and Multiple Cancer Diagnoses.

  2025cites this paper
• Genetic Signature of Human Pancreatic Cancer and Personalized Targeting

  2024cites this paper
• Molecular Targets and Therapies for Ampullary Cancer.

  2024cites this paper
• PANCREATIC CANCER SCREENING: A NARRATIVE REVIEW

  2024cites this paper
• Precursor lesions in familial and hereditary pancreatic cancer

  2024cites this paper
• Advancements in Early Detection and Screening Strategies for Pancreatic Cancer: From Genetic Susceptibility to Novel Biomarkers

  2024influential citation
• There is nothing more obscure than the obvious fact: a case report of breast cancer associated with Peitz–Jeghers syndrome

  2024cites this paper
• Understanding familial risk of pancreatic ductal adenocarcinoma

  2024cites this paper
• A Current Synopsis of the Emerging Role of Extracellular Vesicles and Micro-RNAs in Pancreatic Cancer: A Forward-Looking Plan for Diagnosis and Treatment

  2024cites this paper
• Management des Peutz-Jeghers-Syndroms

  2023cites this paper
• Understanding the Genetic Landscape of Pancreatic Ductal Adenocarcinoma to Support Personalized Medicine: A Systematic Review

  2023cites this paper
• Management des Peutz-Jeghers-Syndroms Management of the Peutz-Jeghers Syndrome

  2023cites this paper
• Earlier Diagnosis of Pancreatic Cancer: Is It Possible?

  2023cites this paper
• Overview of Pancreatic Cancer Epidemiology in Europe and Recommendations for Screening in High-Risk Populations

  2023cites this paper
• Identification of a novel mitochondria-localized LKB1 variant required for the regulation of the oxidative stress response

  2023cites this paper
• STAT3 signaling in pancreatic ductal adenocarcinoma: a candidate therapeutic target.

  2023cites this paper
• Hamartomatous polyps: Diagnosis, surveillance, and management

  2023cites this paper
• Early-Onset Cancer in the Gastrointestinal Tract Is on the Rise-Evidence and Implications.

  2023cites this paper
• Genetics, Genomics and Emerging Molecular Therapies of Pancreatic Cancer

  2023cites this paper
• Risk Factors of Pancreatic Cancer: A Literature Review

  2022cites this paper
• Cancer risk in patients with Peutz-Jeghers syndrome in Korea: a retrospective multi-center study

  2022influential citation
• Surgical management of familial pancreatic cancer: a systematic review of the literature

  2022cites this paper
• Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis syndromes: recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer.

  2022cites this paper
• Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer.

  2022cites this paper
• Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer.

  2022cites this paper
• American Society for Gastrointestinal Endoscopy guideline on screening for pancreatic cancer in individuals with genetic susceptibility: methodology and review of evidence.

  2022cites this paper
• Hereditary pancreatic cancer.

  2022cites this paper
• Familial Predisposition and Genetic Risk Factors Associated with Pancreatic Cancer.

  2022cites this paper
• Serine/Threonine Kinase 11 Plays a Canonical Role in Malignant Progression of KRAS-Mutant and GNAS-Wild-Type Intraductal Papillary Mucinous Neoplasms of the Pancreas

  2021cites this paper
• Diffusion Weighted Imaging of the Hepatobiliary System: Techniques and Clinical Applications

  2021cites this paper
• Pancreatic Adenocarcinoma, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.

  2021cites this paper
• A Review of Breast Cancer Risk Factors in Adolescents and Young Adults

  2021cites this paper
• Hereditary pancreatic cancer

  2021cites this paper
• Hereditary Syndromes and Pancreatic Cancer

  2021cites this paper
• Pancreas in Hereditary Syndromes: Cross-sectional Imaging Spectrum.

  2021cites this paper
• A Case of Peutz-Jeghers Syndrome Presenting With an Inoperable Periampullary Tumor

  2021cites this paper
• Inherited predisposition to pancreatic cancer.

  2021cites this paper
• Pancreatic cancer pathology viewed in the light of evolution

  2021cites this paper
• The Management of Peutz–Jeghers Syndrome: European Hereditary Tumour Group (EHTG) Guideline

  2021cites this paper
• Register and clinical follow-up of patients with Peutz-Jeghers syndrome in Valencia.

  2020cites this paper
• Developing effective combination therapy for pancreatic cancer: an overview.

  2020cites this paper
• Pancreatic Cystic Neoplasms

  2020cites this paper
• Identification and characterisation of germline variants in an Irish cohort with breast cancer

  2020cites this paper
• The genetics of ductal adenocarcinoma of the pancreas in the year 2020: dramatic progress, but far to go

  2020influential citation
• Updated risk factors to inform early pancreatic cancer screening and identify high risk patients.

  2020cites this paper
• Register and clinical follow-up of patients with Peutz-Jeghers syndrome in Valencia

  2020cites this paper
• Hamartomatous Polyposis Syndromes: Management and Surveillance Strategies

  2020cites this paper
• Peutz-Jeghers syndrome

  2019cites this paper
• Pancreatic Cancer

  2019cites this paper
• Pancreatic and Periampullary Cancer

  2019cites this paper
• General Discussion and Future Perspectives

  2019cites this paper
• Hereditary gastrointestinal cancers: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

  2019cites this paper
• Hereditary Gastrointestinal Cancers

  2019cites this paper
• Pre-Empting Pancreatic Cancer : Masking Co-Founders and Unmasking Biomarkers

  2018cites this paper
• Familial Pancreatic Cancer

  2018cites this paper
• Metachronous triple cancer associated with Peutz–Jeghers syndrome treated with curative surgery: a case report

  2018cites this paper
• New Hope for Pancreatic Ductal Adenocarcinoma Treatment Targeting Endoplasmic Reticulum Stress Response: A Systematic Review

  2018cites this paper
• Genetic Alterations of Periampullary and Pancreatic Ductal Adenocarcinoma: An Overview

  2018cites this paper
• Screening to Detect Precursor Lesions of Pancreatic Adenocarcinoma in High-risk Individuals: A Single-center Experience

  2018cites this paper
• Interested in publishing with us ? Contact book

  2018cites this paper
• Hereditary Pancreatic Cancer

  2017cites this paper
• The role of STK 11 gene testing in individuals with oral pigmentation

  2017cites this paper
• Pancreatic Cancer Screening

  2017cites this paper
• Advances in Hereditary Colorectal and Pancreatic Cancer

  2017cites this paper
• Inherited pancreatic cancer.

  2017cites this paper
• Prevalence and Progression of Pancreatic Cystic Precursor Lesions Differ Between Groups at High Risk of Developing Pancreatic Cancer

  2017cites this paper
• Case series of multiple primary cancers in single individuals: diagnostic and therapeutic dilemmas

  2017cites this paper
• Diagnostic value of selected markers and apoptotic pathways for pancreatic cancer

  2017cites this paper
• Gastrointestinal diseases and their oro-dental manifestations: Part 4: Peutz-Jeghers syndrome

  2017cites this paper
• What's unique about acute pancreatitis in children: risk factors, diagnosis and management

  2017cites this paper
• Cancer risk in patients with Peutz–Jeghers syndrome: A retrospective cohort study of 336 cases

  2017cites this paper
• Hereditary pancreatic cancer: related syndromes and clinical perspective

  2017cites this paper
• Diagnosis and Management of Hereditary Pancreatic Cancer.

  2016cites this paper
• Advances in Hereditary Colorectal and Pancreatic Cancers.

  2016cites this paper
• LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

  2016cites this paper
• Role of the microenvironment in chronic pancreatitis and pancreatic cancer

  2016cites this paper
• Consultation d’oncogénétique en pathologie colique et stratégie de surveillance

  2016cites this paper
• Síndrome de Peutz- Jeghers. Presentación de cinco casos

  2016influential citation
• How to Manage Cystic Tumors of the Pancreas in High-Risk Individuals

  2016cites this paper
• Systemic Therapy in Pancreatic Cancer

  2016cites this paper
• Validation and early qualification of pancreatic fat deposition as an imaging biomarker of pancreatic cancer risk

  2016cites this paper
• Prognostic factors in periampullary adenocarcinoma. A retrospective study over an 11 year period.

  2016cites this paper
• Familial pancreatic cancer.

  2016cites this paper
• Update on our investigation of malignant tumors associated with Peutz–Jeghers syndrome in Japan

  2016cites this paper
• [Rare hereditary syndromes associated with polyposis and the development of malignant tumors].

  2016cites this paper
• Support Vector Machine Based on microRNA Expression Profiles to Predict Histological Origin of Ampullary Carcinoma: Case Report of a Patient Affected From Adenocarcinoma of the Papilla of Vater With Lynch Syndrome

  2016influential citation
• Increased Incidence of Second Primary Pancreatic Cancer in Patients with Prior Colorectal Cancer: A Population-Based US Study

  2016cites this paper
• High risk factors of pancreatic carcinoma

  2016cites this paper
• Factors associated with cancer worries in individuals participating in annual pancreatic cancer surveillance

  2016cites this paper
• Pancreatic Cancer Genetics

  2016cites this paper
• The detection of tumor location and lymph node metastasis by aberrant NXPH1 and NXPH2 expressions in pancreatic ductal adenocarcinomas.

  2016cites this paper