Early pregnancy maternal endocrine insulin-like growth factor I programs the placenta for increased functional capacity throughout gestation.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Endocrinology

• Publication date

  2007-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/EN.2007-0411PMID 17525121
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Early treatment of the pregnant guinea pig with IGFs promotes placental transport and nutrient partitioning near term.

  2007cited by this paper
• Differential Expression of Glucose Transporters in Rabbit Placenta: Effect of Hypercholesterolemia in Dams1

  2007cited by this paper
• Maternal insulin-like growth factors-I and -II act via different pathways to promote fetal growth.

  2006cited by this paper
• SNAT4 isoform of system A amino acid transporter is expressed in human placenta.

  2006cited by this paper
• Down‐regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet

  2006cited by this paper
• IGF regulation of neutral amino acid transport in the BeWo choriocarcinoma cell line (b30 clone): evidence for MAP kinase-dependent and MAP kinase-independent mechanisms.

  2006cited by this paper
• Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems.

  2005cited by this paper
• Differential regulation of the GLUT1 and GLUT3 glucose transporters by growth factors and pro-inflammatory cytokines in equine articular chondrocytes.

  2005cited by this paper
• Glucose transporter isoform 4 is expressed in the syncytiotrophoblast of first trimester human placenta.

  2005cited by this paper
• Localisation of glucose transport in the ruminant placenta: implications for sequential use of transporter isoforms.

  2005cited by this paper
• High Glucose Levels Down-Regulate Glucose Transporter Expression That Correlates With Increased Oxidative Stress in Placental Trophoblast Cells IN Vitro

  2004cited by this paper
• Insulin-like growth factor-II regulates the expression of vascular endothelial growth factor by the human keratinocyte cell line HaCaT.

  2004cited by this paper
• Characterization of glucose transporter 8 (GLUT8) in the ovine placenta of normal and growth restricted fetuses.

  2004cited by this paper
• Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family

  2004cited by this paper
• The developmental origins of well-being.

  2004cited by this paper
• Induction of glucose transporter 1 expression through hypoxia-inducible factor 1alpha under hypoxic conditions in trophoblast-derived cells.

  2004cited by this paper
• Distinct regulation of glucose transport and GLUT1/GLUT3 transporters by glucose deprivation and IGF-I in chromaffin cells.

  2003cited by this paper
• Possible angiogenic roles of insulin-like growth factor II and its receptors in uterine vascular adaptation to pregnancy.

  2003cited by this paper
• GLUT12 expression in human placenta in first trimester and term.

  2003cited by this paper
• The insulin-like growth factors and feto-placental growth.

  2003cited by this paper
• Effects of food restriction and pregnancy on the expression of insulin-like growth factors-I and -II in tIssues from guinea pigs.

  2003cited by this paper
• A new quantitative method of real time reverse transcription polymerase chain reaction assay based on simulation of polymerase chain reaction kinetics.

  2002cited by this paper
• Physiological importance of system A-mediated amino acid transport to rat fetal development.

  2002cited by this paper
• Circulating insulin-like growth factor (IGF)-I and IGF binding proteins -1 and -3 and placental development in the guinea-pig.

  2002cited by this paper
• Glucose transport and system A activity in syncytiotrophoblast microvillous and basal plasma membranes in intrauterine growth restriction.

  2002cited by this paper
• Validation of a quantitative method for real time PCR kinetics.

  2002cited by this paper
• Placental glucose transfer and fetal growth

  2002cited by this paper
• Amino Acid Transporters in the Human Placenta

  2001cited by this paper
• Maternal nutrition affects the ability of treatment with IGF-I and IGF-II to increase growth of the placenta and fetus, in guinea pigs.

  2001cited by this paper
• Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A.

  2000cited by this paper
• Spatial and temporal patterns of expression of messenger RNA for insulin-like growth factors and their binding proteins in the placenta of man and laboratory animals.

  2000cited by this paper
• Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta.

  2000cited by this paper
• Time-dependent physiological regulation of rodent and ovine placental glucose transporter (GLUT-1) protein.

  1998cited by this paper
• Time-dependent physiological regulation of rodent and ovine placental glucose transporter (GLUT-1) protein.

  1998cited by this paper
• Phosphorylated insulin‐like growth factor (IGF) —Binding protein‐1 (IGFBP‐1) inhibits while nonphosphorylated IGFBP‐1 stimulates IGF‐I‐induced amino acid uptake by cultured trophoblast cells

  1998cited by this paper
• Insulin-like growth factor II induced by hypoxia may contribute to angiogenesis of human hepatocellular carcinoma.

  1998cited by this paper
• Levels and patterns of intrauterine growth retardation in developing countries.

  1998cited by this paper
• Fetal growth and placental function.

  1998cited by this paper
• Insulin-like growth factor II (IGF-II) secreted from HepG2 human hepatocellular carcinoma cells shows angiogenic activity.

  1998cited by this paper
• Phosphorylated insulin-like growth factor (IGF)-binding protein-1 (IGFBP-1) inhibits while non-phosphorylated IGFBP-1 stimulates IGF-I-induced amino acid uptake by cultured trophoblast cells.

  1998cited by this paper
• Substrate autoregulation of glucose transport: hexose 6-phosphate mediates the cellular distribution of glucose transporters

  1997cited by this paper
• Developmental increases in glucose transporter concentration in the sheep placenta.

  1997cited by this paper
• Placental transporter activity and expression in relation to fetal growth

  1997cited by this paper
• Association between the Activity of the System A Amino Acid Transporter in the Microvillous Plasma Membrane of the Human Placenta and Severity of Fetal Compromise in Intrauterine Growth Restriction

  1997cited by this paper
• The effect of hypoxia on human trophoblast in culture: morphology, glucose transport and metabolism.

  1997cited by this paper
• Gestational changes of glucose transporter gene expression in the mouse placenta and decidua

  1996cited by this paper
• Regulation of cell surface GLUT1, GLUT3, and GLUT4 by insulin and IGF‐I in L6 myotubes

  1995cited by this paper
• Localisation of the high affinity factilitative glucose transporter protein GLUT 1 in the placenta of human, marmoset monkey (Callithrix jacchus) and rat at different developmental stages

  1995cited by this paper
• Insulin‐like growth factor‐1 stimulates amino acid uptake by the cultured human placental trophoblast

  1995cited by this paper
• Elimination of leprosy as a public health problem: progress and prospects.

  1995cited by this paper
• Maternal anthropometry and pregnancy outcomes. A WHO Collaborative Study.

  1995cited by this paper
• Epidermal growth factor and insulin-like growth factor I differently influence the directional accumulation and transfer of 2-aminoisobutyrate (AIB) by human placental trophoblast in two-sided culture.

  1994cited by this paper
• Insulinlike growth factors. Their regulation of glucose and amino acid transport in placental trophoblasts isolated from first-trimester chorionic villi.

  1994cited by this paper
• Immunolocalization of glucose transporter GLUT1 in the rat placental barrier: possible role of GLUT1 and the gap junction in the transport of glucose across the placental barrier

  1994cited by this paper
• Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r).

  1993cited by this paper
• Role of insulin-like growth factors in embryonic and postnatal growth.

  1993cited by this paper
• Longitudinal follow‐up of growth in children born small for gestational age

  1993cited by this paper
• Placental glucose transporter gene expression and metabolism in the rat.

  1993cited by this paper
• Glucose transporter protein expression in human placenta throughout gestation and in intrauterine growth retardation.

  1993cited by this paper
• Association of intrauterine fetal growth retardation and learning deficits at age 9 to 11 years.

  1992cited by this paper
• Detection of the GLUT3 facilitative glucose transporter in rat L6 muscle cells: regulation by cellular differentiation, insulin and insulin-like growth factor-I.

  1992cited by this paper
• Acute and long‐term effects of insulin‐like growth factor I on glucose transporters in muscle cells Translocation and biosynthesis

  1992cited by this paper
• Adaptations of glucose and fatty acid metabolism during perinatal period and suckling-weaning transition.

  1992cited by this paper
• Endocrine and substrate control of fetal growth: placental and maternal influences and insulin-like growth factors.

  1991cited by this paper
• Circulating levels of insulin-like growth factors increase and molecular forms of their serum binding proteins change with human pregnancy.

  1990cited by this paper
• Impact of intrauterine growth retardation and body proportionality on fetal and neonatal outcome.

  1990cited by this paper
• Stabilization of glucose transporter mRNA by insulin/IGF-1 and glucose deprivation.

  1990cited by this paper
• A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

  1990cited by this paper
• Lysine and alanine transport in the perfused guinea-pig placenta.

  1989cited by this paper
• Alanine transport systems in isolated basal plasma membrane of human placenta.

  1989cited by this paper
• Endocrine control of fetal growth.

  1989cited by this paper
• The Physiology of reproduction

  1988cited by this paper
• Neutral amino acid transport systems of microvillous membrane of human placenta.

  1988cited by this paper
• L-alanine carriers at maternal and fetal surfaces of the guinea pig placenta trophoblast.

  1986cited by this paper

• A human cytotrophoblast-villous endothelium-fetal organ multi-cell model and the impact on gene and protein expression in placenta cytotrophoblast, fetal hepatocytes and fetal kidney epithelial cells

  2025cites this paper
• Cord blood levels of insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 correlate with perinatal brain development in fetal congenital heart disease

  2025cites this paper
• A human cytotrophoblast-villous endothelium-fetal organ multi-cell model and the impact on gene and protein expression in placenta cytotrophoblast, fetal hepatocytes and fetal kidney epithelial cells.

  2025cites this paper
• Environmental and genetic risk factors for preterm birth: interplays with stressful events during pregnancy

  2025cites this paper
• Dairy Consumption and Its Impact on PCOS and the Reproductive System: The Connection

  2025cites this paper
• Gene therapy in nonhuman primates: a pilot study of maternal, placental and fetal response to non-viral, polymeric nanoparticle delivery of IGF1.

  2024cites this paper
• Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates

  2023cites this paper
• Evaluation of Feeding Beta-Hydroxy-Beta-Methylbutyrate (HMB) to Mouse Dams during Gestation on Birth Weight and Growth Variation of Offspring

  2023cites this paper
• Effects of maternal HF diet and absence of TRPC1 gene on mouse placental growth and fetal intrauterine growth retardation (IUGR).

  2022cites this paper
• The growth hormone-insulin like growth factor axis in pregnancy.

  2021cites this paper
• Gestational diabetes: Implications for fetal growth, intervention timing, and treatment options.

  2021cites this paper
• Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth

  2020cites this paper
• Embryo gene expression in pig pregnancy.

  2020cites this paper
• Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric 1 oxide synthase to support trophoblast function and normal fetal growth 2 3

  2020cites this paper
• Validation studies of a fluorescent method to measure placental glucose transport in mice.

  2019cites this paper
• Evaluation Of Supplementation Of The Leucine Metabolite, Β-Hydroxy-Β-Methylbutyrate (HMB), During Gestation To Mouse Dams On Offspring Birth Weight And Growth Variation

  2019cites this paper
• dl-Methionine supplementation in a low-fishmeal diet affects the TOR/S6K pathway by stimulating ASCT2 amino acid transporter and insulin-like growth factor-I in the dorsal muscle of juvenile cobia (Rachycentron canadum).

  2019cites this paper
• Multifaceted regulation of the system A transporter Slc38a2 suggests nanoscale regulation of amino acid metabolism and cellular signaling.

  2019cites this paper
• IUGR Is Associated With Marked Hyperphosphorylation of Decidual and Maternal Plasma IGFBP-1

  2018cites this paper
• Assessment of Placental Transport Function in Studies of Disease Programming.

  2018cites this paper
• Novel roles of mechanistic target of rapamycin signaling in regulating fetal growth†.

  2018cites this paper
• A Western‐style obesogenic diet alters maternal metabolic physiology with consequences for fetal nutrient acquisition in mice

  2017cites this paper
• Maternal IGF1 and IGF1R polymorphisms and the risk of spontaneous preterm birth

  2017cites this paper
• Development and validation of a novel clinical fluorescence in situ hybridization assay to detect JAK2 and PD-L1 amplification: a fluorescence in situ hybridization assay for JAK2 and PD-L1 amplification

  2017cites this paper
• Regulation of Placental Amino Acid Transport and Fetal Growth.

  2017cites this paper
• Placental phenotype and the insulin‐like growth factors: resource allocation to fetal growth

  2017cites this paper
• A review of fundamental principles for animal models of DOHaD research: an Australian perspective.

  2016cites this paper
• Review: Endocrine regulation of placental phenotype.

  2015cites this paper
• Maternal insulin-like growth factor 1 and 2 differentially affect the renin-angiotensin system during pregnancy in the guinea pig.

  2015influential citation
• Circulating IGF-1 may mediate improvements in haemoglobin associated with vitamin A status during pregnancy in rural Nepalese women.

  2015cites this paper
• Implication of milk and dairy products consumption through insulin-like growth factor-I in induction of breast cancer risk factors in women

  2015cites this paper
• Chronic prenatal ethanol exposure alters expression of central and peripheral insulin signaling molecules in adult guinea pig offspring.

  2014cites this paper
• Long-Term Outcomes After Intrauterine Therapy of the Growth-Restricted Fetus

  2014cites this paper
• Chronic prenatal ethanol exposure produces neurobehavioural and metabolic dysfunction in guinea pig offspring

  2014cites this paper
• Quantificação de IGF-I no plasma seminal de suínos e sua importância na utilização após o resfriamento e congelamento do sêmen

  2014cites this paper
• Circulating IGF1 and IGF2 and SNP genotypes in men and pregnant and non-pregnant women

  2014cites this paper
• Circulating IGF 1 and IGF 2 and SNP genotypes inmen and pregnant and non-pregnant women

  2014cites this paper
• Regulation of Human Trophoblast GLUT1 Glucose Transporter by Insulin-Like Growth Factor I (IGF-I)

  2014cites this paper
• Circulating IGF1 and IGF2 and SNP genotypes in pregnant and non-pregnant women and men

  2014cites this paper
• Fetal growth factors and fetal nutrition.

  2013cites this paper
• Hormonal and nutritional drivers of intrauterine growth

  2013cites this paper
• Increased Placental Nutrient Transporter Expression at Midgestation after Maternal Growth Hormone Treatment in Pigs: A Placental Mechanism for Increased Fetal Growth1

  2012cites this paper
• Evolution of placental function in mammals: the molecular basis of gas and nutrient transfer, hormone secretion, and immune responses.

  2012cites this paper
• The Potential of Gene Therapy as a Treatment Strategy for Intra-uterine Growth Restriction

  2012cites this paper
• Biology and significance of signalling pathways activated by IGF-II

  2012influential citation
• Placental volume and vascularization flow indices by 3D power Doppler US using VOCAL technique and correlation with IGF-1, free beta-hCG, PAPP-A, and uterine artery Doppler at 11–14 weeks of pregnancy

  2011cites this paper
• The role of placental alkaline phosphatase in the regulation of insulin-like growth factor binding protein-1 in pregnancy complicated by diabetes.

  2011cites this paper
• Environmental regulation of placental phenotype: implications for fetal growth.

  2011cites this paper
• Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

  2011cites this paper
• Maternal growth factor regulation of human placental development and fetal growth.

  2010cites this paper
• The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth

  2010cites this paper
• Embryo-fetal developmental toxicity of figitumumab, an anti-insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibody, in cynomolgus monkeys.

  2010cites this paper
• Maternal-placental insulin-like growth factor (IGF) signaling and its importance to normal embryo-fetal development.

  2010cites this paper
• Hormones as epigenetic signals in developmental programming

  2009cites this paper
• Permanent impairment of insulin resistance from pregnancy to adulthood: the primary basic risk factor of chronic Western diseases.

  2009cites this paper
• Physiological acromegaly of pregnancy

  2009cites this paper
• Responses to maternal GH or ractopamine during early-mid pregnancy are similar in primiparous and multiparous pregnant pigs.

  2009cites this paper
• Placental efficiency and adaptation: endocrine regulation

  2009influential citation
• Milk consumption: aggravating factor of acne and promoter of chronic diseases of Western societies

  2009cites this paper
• Milk--the promoter of chronic Western diseases.

  2009influential citation
• Distinct actions of insulin-like growth factors (IGFs) on placental development and fetal growth: lessons from mice and guinea pigs.

  2008cites this paper
• The role of endocrine insulin-like growth factor-I (IGF-I) in female bovine reproduction.

  2008cites this paper
• Does the Physiological Acromegaly of Pregnancy Benefit the Fetus?

  2008cites this paper
• Maternal insulin-like growth factor-II promotes placental functional development via the type 2 IGF receptor in the guinea pig.

  2008cites this paper
• Diabetes mellitus gestacional

  2008cites this paper
• A 30-kDa fragment of insulin-like growth factor (IGF) binding protein-3 in human pregnancy serum with strongly reduced IGF-I binding

  2007cites this paper
• Insulin-like growth factor binding protein-3 : structure and function

  2007cites this paper
• Insulin-Like Growth Factor-Binding Protein 3

  2007cites this paper