Peripheral neuropathy and neurosteroid formation in the central nervous system.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Brain Research Reviews

• Publication date

  2008-03-14

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/J.BRAINRESREV.2007.05.007PMID 17617466
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Studies on neurosteroids XIX. Development and validation of liquid chromatography-tandem mass spectrometric method for determination of 5alpha-reduced pregnane-type neurosteroids in rat brain and serum.

  2007cited by this paper
• Neurogenic pain and steroid synthesis in the spinal cord

  2007cited by this paper
• Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis.

  2007cited by this paper
• Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: allopregnanolone as a proof of concept neurogenic agent.

  2006cited by this paper
• Preclinical analyses of the therapeutic potential of allopregnanolone to promote neurogenesis in vitro and in vivo in transgenic mouse model of Alzheimer's disease.

  2006cited by this paper
• Peripheral axonal injury results in reduced μ opioid receptor pre‐ and post‐synaptic action in the spinal cord☆

  2005cited by this paper
• Effect of streptozotocin-induced diabetes on the gene expression and biological activity of 3beta-hydroxysteroid dehydrogenase in the rat spinal cord.

  2005cited by this paper
• Neurosteroids: endogenous regulators of the GABAA receptor

  2005cited by this paper
• Molecular and neurochemical evidence for the biosynthesis of dehydroepiandrosterone in the adult rat spinal cord

  2005cited by this paper
• The Neurosteroid Allopregnanolone Promotes Proliferation of Rodent and Human Neural Progenitor Cells and Regulates Cell-Cycle Gene and Protein Expression

  2005cited by this paper
• Caspase signalling in neuropathic and inflammatory pain in the rat

  2004cited by this paper
• Impact of neuropathic pain on the gene expression and activity of cytochrome P450side-chain-cleavage in sensory neural networks

  2004cited by this paper
• Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination.

  2004cited by this paper
• Niemann–Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

  2004cited by this paper
• Cellular distribution and bioactivity of the key steroidogenic enzyme, cytochrome P450side chain cleavage, in sensory neural pathways

  2003cited by this paper
• Aromatase: a neuroprotective enzyme.

  2003cited by this paper
• Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.

  2003cited by this paper
• Animal and cellular models of chronic pain.

  2003cited by this paper
• Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease.

  2002cited by this paper
• The nucleus accumbens as a site of action for rewarding properties of testosterone and its 5α-reduced metabolites

  2002cited by this paper
• Neurosteroids: biochemistry and clinical significance.

  2002cited by this paper
• The nucleus accumbens as a site of action for rewarding properties of testosterone and its 5alpha-reduced metabolites.

  2002cited by this paper
• Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

  2002cited by this paper
• Descending control of pain.

  2002cited by this paper
• Partial Peripheral Nerve Injury Promotes a Selective Loss of GABAergic Inhibition in the Superficial Dorsal Horn of the Spinal Cord

  2002cited by this paper
• Apoptotic genes expression in the lumbar dorsal horn in a model neuropathic pain in rat

  2002cited by this paper
• Metabotropic Neurosteroid/ς-Receptor Involved in Stimulation of Nociceptor Endings of Mice

  2001cited by this paper
• Cell death in the superficial dorsal horn in a model of neuropathic pain

  2001cited by this paper
• Antinociceptive properties of neurosteroids IV: pilot study demonstrating the analgesic effects of alphadolone administered orally to humans.

  2001cited by this paper
• Antinociceptive properties of neurosteroids III: experiments with alphadolone given intravenously, intraperitoneally, and intragastrically.

  2001cited by this paper
• Progesterone and 3alpha,5alpha-THP enhance sexual receptivity in mice.

  2001cited by this paper
• Steroid-induced plasticity in the sexually dimorphic vasotocinergic innervation of the avian brain: behavioral implications.

  2001cited by this paper
• Neurosteroids: recent findings.

  2001cited by this paper
• Neuroprotection by estradiol.

  2001cited by this paper
• Neurosteroid metabolism in the human brain.

  2001cited by this paper
• Metabotropic neurosteroid/sigma-receptor involved in stimulation of nociceptor endings of mice.

  2001cited by this paper
• Progesterone and 3α,5α-THP enhance sexual receptivity in mice.

  2001cited by this paper
• Neurosteroids: biosynthesis and function of these novel neuromodulators.

  2000cited by this paper
• Pregnenolone binds to microtubule-associated protein 2 and stimulates microtubule assembly.

  2000cited by this paper
• Antinociceptive properties of neurosteroids II. Experiments with Saffan® and its components alphaxalone and alphadolone to reveal separation of anaesthetic and antinociceptive effects and the involvement of spinal cord GABAA receptors

  2000cited by this paper
• Antinociceptive properties of neurosteroids I. Spinally‐mediated antinociceptive effects of water‐soluble aminosteroids

  2000cited by this paper
• Neuronal plasticity: increasing the gain in pain.

  2000cited by this paper
• The induction of pain: an integrative review.

  1999cited by this paper
• Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system.

  1999cited by this paper
• Progesterone is neuroprotective after acute experimental spinal cord trauma in rats.

  1999cited by this paper
• Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine.

  1998cited by this paper
• Gestational and ovarian sex steroid antinociception: synergy between spinal κ and δ opioid systems

  1998cited by this paper
• Gestational and ovarian sex steroid antinociception: synergy between spinal kappa and delta opioid systems.

  1998cited by this paper
• Neurosteroids: Expression of Functional 3β‐Hydroxysteroid Dehydrogenase by Rat Sensory Neurons and Schwann Cells

  1997cited by this paper
• Involvement of spinal cord δ opiate receptors in the antinociception of gestation and its hormonal simulation

  1997cited by this paper
• In Vivo and In Vitro Evidence for the Biosynthesis of Testosterone in the Telencephalon of the Female Frog

  1996cited by this paper
• Behavioral effects of 3a-androstanediol II: Hypothalamic and preoptic area actions via a GABAergic mechanism

  1996cited by this paper
• Localization of 17beta-hydroxysteroid dehydrogenase and characterization of testosterone in the brain of the male frog.

  1996cited by this paper
• Behavioral effects of 3 alpha-androstanediol. II: Hypothalamic and preoptic area actions via a GABAergic mechanism.

  1996cited by this paper
• Immunocytochemical localization and biological activity of 3 beta- hydroxysteroid dehydrogenase in the central nervous system of the frog

  1994cited by this paper
• Further evidence for ‘pain‐related’ behaviours in a model of unilateral peripheral mononeuropathy

  1990cited by this paper
• A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

  1988cited by this paper
• Neurosteroids: cytochrome P-450scc in rat brain.

  1987cited by this paper
• Spatial pattern of nerve fiber abnormality indicative of pathologic mechanism.

  1984cited by this paper

• Impact of Designated Recovery Rehabilitation Institutions on the Readmission Rate of Older Adults

  2026cites this paper
• Modulatory role of neurosteroidogenesis in the spinal cord during peripheral nerve injury-induced chronic pain.

  2024cites this paper
• Electrophysiological evidence that TRPM3 is a candidate in latent spinal sensitization of chronic low back pain.

  2023cites this paper
• Advances in steroid research from the pioneering neurosteroid concept to metabolomics: New insights into pregnenolone function.

  2023cites this paper
• The effect of progesteron for expression delta (δ) opioid receptor spinal cord through peripheral nerve injury

  2022cites this paper
• Spinal Nitric Oxide Synthase Type II Increases Neurosteroid-metabolizing Cytochrome P450c17 Expression in a Rodent Model of Neuropathic Pain

  2019cites this paper
• Neurosteroids and Neuropathic Pain Management: basic evidence and therapeutic perspectives.

  2019cites this paper
• Neurosteroidogenesis and progesterone anti‐inflammatory/neuroprotective effects

  2018cites this paper
• Exploring the potential of natural and synthetic neuroprotective steroids against neurodegenerative disorders: A literature review

  2018cites this paper
• Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain.

  2017cites this paper
• Neurosteroids and potential therapeutics: Focus on pregnenolone.

  2016cites this paper
• Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation

  2015cites this paper
• Mitochondria, neurosteroids and biological rhythms : implications in health and disease states

  2015cites this paper
• New aspects of 24(S)-hydroxycholesterol in modulating neuronal cell death.

  2015cites this paper
• Assessment of neuroprotective effects of gamma-hydroxybutyrate and neurosteroids on cellular models of Alzheimer’s disease

  2014cites this paper
• Neuroprotection by steroids after neurotrauma in organotypic spinal cord cultures: a key role for progesterone receptors and steroidal modulators of GABA(A) receptors.

  2013cites this paper
• Sigma 1 receptor: a new therapeutic target for pain.

  2013cites this paper
• Comparative Analysis of Gelsemine and Gelsemium sempervirens Activity on Neurosteroid Allopregnanolone Formation in the Spinal Cord and Limbic System

  2011cites this paper
• Evidences for Antinociceptive Effect of 17-Alpha-Hydroxyprogesterone Caproate in Carpal Tunnel Syndrome

  2011cites this paper
• Steroids, spinal cord and pain sensation

  2011cites this paper
• Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats

  2011cites this paper
• Neuroactive steroids: focus on human brain.

  2011cites this paper
• Neurosteroids and Pain

  2011cites this paper
• Sciatic nerve injury induces apoptosis of dorsal root ganglion satellite glial cells and selectively modifies neurosteroidogenesis in sensory neurons

  2010cites this paper
• Selective regulation of 3&agr;‐hydroxysteroid oxido‐reductase expression in dorsal root ganglion neurons: A possible mechanism to cope with peripheral nerve injury‐induced chronic pain

  2010cites this paper
• Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma‐1 and GABAA receptors

  2009cites this paper
• NOVEL PHARMACOLOGICAL APPROACHES TO SCHWANN CELLS AS NEUROPROTECTIVE AGENTS FOR PERIPHERAL NERVE REGENERATION

  2009cites this paper
• Chapter 15: Novel pharmacological approaches to Schwann cells as neuroprotective agents for peripheral nerve regeneration.

  2009cites this paper
• Evidence for a key role of steroids in the modulation of pain.

  2009cites this paper
• Critical commentary 3: steroid dysregulation and stomatodynia (burning mouth syndrome).

  2009cites this paper
• Intrathecal Injection of the &sfgr;1 Receptor Antagonist BD1047 Blocks Both Mechanical Allodynia and Increases in Spinal NR1 Expression during the Induction Phase of Rodent Neuropathic Pain

  2008cites this paper
• The endocrine nervous system: source and target for neuroactive steroids.

  2008cites this paper
• Progesterone and progestins: neuroprotection and myelin repair.

  2008cites this paper
• Regulation of neurosteroid allopregnanolone biosynthesis in the rat spinal cord by glycine and the alkaloidal analogs strychnine and gelsemine.

  2008cites this paper
• Regulatory role of cytochrome P450scc and pregnenolone in myelination by rat Schwann cells

  2008cites this paper