Hippocampal dopamine D2 receptors correlate with memory functions in Alzheimer's disease

No abstract is available for this paper.

• Publication year

  2003

• Venue

  European Journal of Neuroscience

• Publication date

  2003-07-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1046/j.1460-9568.2003.02716.xPMID 12859348
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neuropathological stageing of Alzheimer-related changes

  2004cited by this paper
• Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment

  2002cited by this paper
• Involvement of dopamine D(2) receptors in complex maze learning and acetylcholine release in ventral hippocampus of rats.

  2001cited by this paper
• PET shows that striatal dopamine D1 and D2 receptors are differentially affected in AD

  2000cited by this paper
• Neuroprotective Role of Dopamine Against Hippocampal Cell Death

  2000cited by this paper
• Age-related cognitive deficits mediated by changes in the striatal dopamine system.

  2000cited by this paper
• Extrastriatal dopamine D2 and D3 receptors in early and advanced Parkinson’s disease

  2000cited by this paper
• Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study.

  2000cited by this paper
• Relationships between striatal dopamine denervation and frontal executive tests in Parkinson's disease.

  1999cited by this paper
• Regional cerebral volume loss associated with verbal learning and memory in dementia of the Alzheimer type.

  1999cited by this paper
• Ventral hippocampal dopamine D1 and D2 systems and spatial working memory in rats.

  1999cited by this paper
• Cholinergic markers in elderly patients with early signs of Alzheimer disease.

  1999cited by this paper
• Striatal uptake of the dopamine reuptake ligand [11C]β-CFT is reduced in Alzheimer's disease assessed by positron emission tomography

  1998cited by this paper
• Memory impairments associated with hippocampal versus parahippocampal-gyrus atrophy: an MR volumetry study in Alzheimer's disease.

  1998cited by this paper
• Lisuride Treatment of Alzheimer's Disease A Preliminary Placebo‐Controlled Clinical Trial of Safety and Therapeutic Efficacy

  1998cited by this paper
• Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate.

  1998cited by this paper
• Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals.

  1998cited by this paper
• MRI of the hippocampus in Alzheimer's disease: sensitivity, specificity, and analysis of the incorrectly classified subjects.

  1998cited by this paper
• Dopamine D2 receptor agonists protect against ischaemia-induced hippocampal neurodegeneration in global cerebral ischaemia.

  1998cited by this paper
• Etiology and pathogenesis of Alzheimer's disease.

  1998cited by this paper
• Dopamine D2 receptor bands in normal human temporal cortex are absent in Alzheimer's disease.

  1998cited by this paper
• A PET-study of [11C]FLB 457 binding to extrastriatal D2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients

  1997cited by this paper
• Simplified reference tissue model for PET receptor studies.

  1996cited by this paper
• Reduced striatal dopamine receptors in Alzheimer's disease

  1996cited by this paper
• Autoradiographic localisation of D3-dopamine receptors in the human brain using the selective D3-dopamine receptor agonist (+)-[3H]PD 128907

  1996cited by this paper
• Activation of medial temporal structures during episodic memory retrieval

  1996cited by this paper
• Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors.

  1995cited by this paper
• Loss of dopamine D2 receptors varies along the rostrocaudal axis of the hippocampal complex in alzheimer's disease

  1994cited by this paper
• Localization of dopamine D3 receptors to mesolimbic and D2 receptors to mesostriatal regions of human forebrain.

  1994cited by this paper
• MRI hippocampal volumes and memory function before and after temporal lobectomy

  1993cited by this paper
• Dopamine D2 receptors in the hippocampus and amygdala in Alzheimer's disease.

  1993cited by this paper
• Atrophy of medial temporal lobes on MRI in "probable" Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates.

  1992cited by this paper
• Accurate Three‐Dimensional Registration of CT, PET, and/or MR Images of the Brain

  1989cited by this paper
• ETIOLOGY AND PATHOGENESIS OF ALZHEIMER'S DISEASE

  1984cited by this paper

• The interaction between neurotransmitter receptor activity and amyloid-β pathology in Alzheimer's disease

  2025cites this paper
• Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models

  2025cites this paper
• Clinical Applications of PET Imaging in Alzheimer's Disease.

  2025cites this paper
• Maternal Diet and Vulnerability to Cognitive Impairment in Adulthood: Possible Link with Alzheimer’s Disease?

  2025cites this paper
• Dopamine System Dysfunction in Alzheimer's Disease

  2025cites this paper
• Breaking boundaries: Dopamine's role in prediction error, salient novelty, and memory reconsolidation.

  2025cites this paper
• Photostimulation of locus coeruleus CA1 catecholaminergic terminals reversed Spatial memory impairment in an alzheimer's disease mouse model.

  2025cites this paper
• Dopaminergic deficits along the spectrum of Alzheimer’s disease

  2025cites this paper
• From Disinfectant to Neurodegeneration: Integrating Machine Learning and Mendelian Randomization Reveals Triclosan as A Novel Environmental Risk Factor for Alzheimer's Disease.

  2025cites this paper
• Differential Modulation of Dopamine D2 Receptor on Somatostatin and Parvalbumin Interneurons in the CA1 Area of the Dorsal Hippocampus

  2025cites this paper
• Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles

  2024cites this paper
• Mechanism of Metal Complexes in Alzheimer’s Disease

  2024cites this paper
• Monoamine alterations in Alzheimer’s disease and their implications in comorbid neuropsychiatric symptoms

  2024cites this paper
• The dopaminergic system and Alzheimer’s disease

  2024cites this paper
• Advances in Brain Stimulation, Nanomedicine and the Use of Magnetoelectric Nanoparticles: Dopaminergic Alterations and Their Role in Neurodegeneration and Drug Addiction

  2024cites this paper
• Drug Repurposing of Metformin for the Treatment of Haloperidol-Related Behavior Disorders and Oxidative Stress: A Preliminary Study

  2024cites this paper
• Longitudinal support for the correlative triad among aging, dopamine D2-like receptor loss, and memory decline.

  2024cites this paper
• Finding Drug Repurposing Candidates for Neurodegenerative Diseases using Zebrafish Behavioral Profiles

  2023cites this paper
• In silico Strategy: A Promising Implement in the Development of Multitarget Drugs against Neurodegenerative Diseases.

  2023cites this paper
• Mesial temporal dopamine: From biology to behaviour

  2023cites this paper
• Targeting dopamine transporter to ameliorate cognitive deficits in Alzheimer's disease

  2023cites this paper
• Mechanistic and therapeutic role of NLRP3 inflammasome in the pathogenesis of Alzheimer's disease

  2023cites this paper
• Dopamine D2 Receptors modulate hippocampal theta rhythm through somatostatin interneurons

  2023cites this paper
• The VTA dopaminergic system as diagnostic and therapeutical target for Alzheimer's disease

  2022cites this paper
• Dopamine D2 receptor agonist Bromocriptine ameliorates Aβ1-42-induced memory deficits and neuroinflammation in mice.

  2022cites this paper
• Understanding How Physical Exercise Improves Alzheimer’s Disease: Cholinergic and Monoaminergic Systems

  2022cites this paper
• Cognitive impairment in alzheimer's and metabolic diseases: A catecholaminergic hypothesis.

  2022cites this paper
• The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer’s disease states

  2022cites this paper
• Amyloid pathology induces dysfunction of systemic neurotransmission in aged APPswe/PS2 mice

  2022cites this paper
• Ventral Tegmental Area Disconnection Contributes Two Years Early to Correctly Classify Patients Converted to Alzheimer’s Disease: Implications for Treatment

  2021cites this paper
• Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer’s disease

  2021cites this paper
• Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease.

  2021cites this paper
• Clustering-based time series analysis on insulin response in the blood-brain barrier

  2021cites this paper
• Alterations and interactions of subcortical modulatory systems in Alzheimer's disease.

  2021cites this paper
• Early derailment of firing properties in CA1 pyramidal cells of the ventral hippocampus in an Alzheimer's disease mouse model.

  2021cites this paper
• The hybrid compounds as multi-target ligands for the treatment of Alzheimer's Disease: Considerations on Donepezil.

  2021cites this paper
• Molecular and Therapeutic Targets for Amyloid-beta Plaques in Alzheimer’s Disease: A Review Study

  2021cites this paper
• Dopaminergic dysfunction in the 3xTg-AD mice model of Alzheimer’s disease

  2021cites this paper
• Association of the MAOB rs1799836 Single Nucleotide Polymorphism and APOE ɛ4 Allele in Alzheimer's Disease.

  2021cites this paper
• Trace amine-associated receptor 1 (TAAR1): Potential Application in Mood Disorders: A Systematic Review.

  2021cites this paper
• A Comprehensive Insight into the Mechanisms of Dopamine in Disrupting Aβ Protofibrils and Inhibiting Aβ Aggregation.

  2021cites this paper
• New frontiers in Alzheimer's disease diagnostic: Monoamines and their derivatives in biological fluids.

  2021cites this paper
• In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer’s disease phases

  2021cites this paper
• Fluoride exposure, dopamine relative gene polymorphism and intelligence: A cross-sectional study in China.

  2020cites this paper
• The dialog between neurons and microglia in Alzheimer's disease: The neurotransmitters view

  2020influential citation
• Neurophysiological biomarkers using transcranial magnetic stimulation in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis.

  2020cites this paper
• Dopamine D2R is Required for Hippocampal-dependent Memory and Plasticity at the CA3-CA1 Synapse

  2020cites this paper
• Ascorbate deficiency decreases dopamine release in gulo–/– and APP/PSEN1 mice

  2020cites this paper
• Effect of Rotigotine vs Placebo on Cognitive Functions Among Patients With Mild to Moderate Alzheimer Disease

  2020cites this paper
• The multi-faceted impact of methamphetamine on Alzheimer's disease: From a triggering role to a possible therapeutic use.

  2020cites this paper
• Local and global dichotomic dysfunction in resting and evoked functional connectivity precedes tauopathy

  2020cites this paper
• The lateral entorhinal cortex is a hub for local and global dysfunction in pre-tauopathy states

  2020cites this paper
• G protein-coupled receptors in neurodegenerative diseases

  2020cites this paper
• True and False Memories: Neuropsychological and Neuropharmacological Approaches

  2019cites this paper
• Monoamines and their derivatives on GPCRs: potential therapy for Alzheimer's Disease.

  2019cites this paper
• Haloperidol-induced impairment on working memory capacity affecting long term memory performance: the binding hypothesis

  2019cites this paper
• Dimeryzacja receptora bradykininy B2 z receptorem dopaminergicznym D2 oraz wpływ oddziaływań pomiędzy nimi na wybrane funkcje komórek śródbłonka

  2019cites this paper
• Proceedings Template-WORD

  2019cites this paper
• Prevention of Alzheimer's disease by treating mild cognitive impairment with combinations chosen from eight available drugs

  2019cites this paper
• White Matter Hyperintensities Relate to Basal Ganglia Functional Connectivity and Memory Performance in aMCI and SVMCI

  2019cites this paper
• β-Amyloid 25–35 Suppresses the Secretory Activity of the Dopaminergic System in the Rat Brain

  2019cites this paper
• Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis

  2019cites this paper
• Monoaminergic System Modulation in Depression and Alzheimer’s Disease: A New Standpoint?

  2019cites this paper
• Dopamine D1 receptor activation improves adult hippocampal neurogenesis and exerts anxiolytic and antidepressant‐like effect via activation of Wnt/&bgr;‐catenin pathways in rat model of Parkinson's disease

  2019cites this paper
• Melatonin in Synaptic Impairments of Alzheimer’s Disease

  2018cites this paper
• Dopaminergic innervation and modulation of hippocampal networks

  2018cites this paper
• Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease.

  2018cites this paper
• 6.11 – Neurotransmitter Receptors☆

  2018cites this paper
• Cognitive Impairment and Dementias.

  2018cites this paper
• Epigenetic Alterations Impact on Antipsychotic Treatment in Elderly Patients

  2018cites this paper
• Visual Scanning and Attentional Biases in Alzheimerâ s Disease: Assessing Symptoms and Outcomes

  2017influential citation
• Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice

  2017cites this paper
• Haloperidol increases false recognition memory of thematically related pictures in healthy volunteers

  2017cites this paper
• Neurological Alterations in Cognitive Impairment

  2017cites this paper
• 18F-fallypride PET-CT of dopamine D2/D3 receptors in patients with sporadic amyotrophic lateral sclerosis.

  2017cites this paper
• Aminergic modulation of hippocampal synaptic plasticity in health and disease

  2017cites this paper
• Visual Selective Attention Toward Novel Stimuli Predicts Cognitive Decline in Alzheimer’s Disease Patients

  2016cites this paper
• Postnatal exposure to PFOS, but not PBDE 99, disturb dopaminergic gene transcription in the mouse CNS.

  2016cites this paper
• Dopamine D2 receptor availability is linked to hippocampal–caudate functional connectivity and episodic memory

  2016cites this paper
• Dopamine D 2 receptor availability is linked to hippocampal – caudate functional connectivity and episodic memory

  2016cites this paper
• Imaging of Neurotransmitter Systems in Dementia

  2016cites this paper
• Effects of Sulpiride on True and False Memories of Thematically Related Pictures and Associated Words in Healthy Volunteers

  2016cites this paper
• Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.

  2016cites this paper
• G-protein coupled receptors as therapeutic targets for neurodegenerative and cerebrovascular diseases.

  2016cites this paper
• Drug Development in Alzheimer’s Disease: The Contribution of PET and SPECT

  2016cites this paper
• Fatty acids rehabilitated long-term neurodegenerative: like symptoms in olfactory bulbectomized rats

  2015cites this paper
• Opposing effects of APP/PS1 and TrkB.T1 genotypes on midbrain dopamine neurons and stimulated dopamine release in vivo.

  2015cites this paper
• Impaired and preserved aspects of feedback learning in aMCI: contributions of structural connectivity

  2015cites this paper
• Catecholamine-Based Treatment in AD Patients: Expectations and Delusions

  2015cites this paper
• , flexibility profile in pathological gamblers Dopamine DRD 2 / ANKK 1 Taq 1 A and DAT 1 VNTR polymorphisms are associated with a cognitive

  2014cites this paper
• Dopaminergic Modulation of Cortical Plasticity in Alzheimer’s Disease Patients

  2014influential citation
• Hippocampal place cell responses to distal and proximal cue manipulations in dopamine D2 receptor-knockout mice.

  2014cites this paper
• PET radiotracers for molecular imaging in dementia.

  2014cites this paper
• Nonamyloid PET biomarkers and Alzheimer's disease: current and future perspectives

  2014cites this paper
• Dopamine differently modulates central cholinergic circuits in patients with Alzheimer disease and CADASIL

  2014cites this paper
• Characterising the neuropsychological profile of psychotic symptoms in Alzheimer's disease and imaging D2/3 receptor occupancy during treatment

  2014cites this paper
• Olfactory bulbectomy as a putative model for Alzheimer’: The protective role of essential fatty acids

  2014cites this paper
• Related Genes and Potential Biomarkers for Early Diagnosis of Alzheimer’s Disease

  2014cites this paper
• Dopamine DRD2/ANKK1 Taq1A and DAT1 VNTR polymorphisms are associated with a cognitive flexibility profile in pathological gamblers

  2014cites this paper
• “Is dopamine involved in Alzheimer's disease?”

  2014cites this paper