Expression of functional leptin receptors in the human ovary.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Journal of Clinical Endocrinology and Metabolism

• Publication date

  1997-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/JCEM.82.12.4446PMID 9398729
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Direct intraovarian effects of leptin: impairment of the synergistic action of insulin-like growth factor-I on follicle-stimulating hormone-dependent estradiol-17 beta production by rat ovarian granulosa cells.

  1997cited by this paper
• Leptin is a metabolic gate for the onset of puberty in the female rat.

  1997cited by this paper
• Leptin Receptor (OB-R) Signaling

  1997cited by this paper
• Demonstration of a leptin binding factor in human serum.

  1997cited by this paper
• Leptin accelerates the onset of puberty in normal female mice.

  1997cited by this paper
• Role of leptin in hypothalamic-pituitary function.

  1997cited by this paper
• Obese (ob) gene defects are rare in human obesity.

  1997cited by this paper
• Early Onset of Reproductive Function in Normal Female Mice Treated with Leptin

  1997cited by this paper
• Direct Intraovarian Effects of Leptin: Impairment of the Synergistic Action of Insulin-Like Growth Factor-I on Follicle-Stimulating Hormone-Dependent Estradiol-17β Production by Rat Ovarian Granulosa Cells.

  1997cited by this paper
• Congenital leptin deficiency is associated with severe early-onset obesity in humans

  1997cited by this paper
• Leptin is normal in PCOS, an editorial about three "negative" papers.

  1997cited by this paper
• Novel B219/OB receptor isoforms: Possible role of leptin in hematopoiesis and reproduction

  1996cited by this paper
• Leptin and leptinomania.

  1996cited by this paper
• Role of leptin in the neuroendocrine response to fasting

  1996cited by this paper
• Abnormal splicing of the leptin receptor in diabetic mice

  1996cited by this paper
• Modulation of Insulin Activities by Leptin

  1996cited by this paper
• Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

  1996cited by this paper
• Serum immunoreactive leptin concentrations in women with polycystic ovary syndrome.

  1996cited by this paper
• Absence of Mutations in the Human OB Gene in Obese/Diabetic Subjects

  1996cited by this paper
• Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance.

  1996cited by this paper
• Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

  1996cited by this paper
• Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting.

  1996cited by this paper
• Defective STAT signaling by the leptin receptor in diabetic mice.

  1996influential reference
• Serum immunoreactive-leptin concentrations in normal-weight and obese humans.

  1996influential reference
• Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice

  1996cited by this paper
• The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations.

  1996cited by this paper
• Attenuation of the Obesity Syndrome of ob/ob Mice by the Loss of Neuropeptide Y

  1996cited by this paper
• Leptin is a metabolic signal to the reproductive system.

  1996cited by this paper
• The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

  1996influential reference
• Identification of Incidental Sequence Polymorphisms and Absence of the db/db Mouse and fa/fa Rat Mutations

  1996cited by this paper
• Identification and expression cloning of a leptin receptor, OB-R.

  1995cited by this paper
• Weight-reducing effects of the plasma protein encoded by the obese gene.

  1995cited by this paper
• Structural Organization and Chromosomal Assignment of the Human obese Gene (*)

  1995cited by this paper
• The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7.

  1995cited by this paper
• Weight loss results in significant improvement in pregnancy and ovulation rates in anovulatory obese women.

  1995cited by this paper
• Jaks and Stats in signaling by the cytokine receptor superfamily.

  1995cited by this paper
• Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity.

  1995cited by this paper
• Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks.

  1995cited by this paper
• Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

  1995cited by this paper
• Effects of the obese gene product on body weight regulation in ob/ob mice.

  1995cited by this paper
• Cytokine signaling through nonreceptor protein tyrosine kinases.

  1995cited by this paper
• The role of neuropeptide Y in the antiobesity action of the obese gene product

  1995cited by this paper
• Positional cloning of the mouse obese gene and its human homologue

  1994influential reference
• Adolescent body mass index and infertility caused by ovulatory disorder.

  1994cited by this paper
• Fat and female fecundity: prospective study of effect of body fat distribution on conception rates.

  1993cited by this paper
• Signalling by receptor tyrosine kinases.

  1993cited by this paper
• Neuropeptide Y administered chronically into the lateral ventricle profoundly inhibits both the gonadotropic and the somatotropic axis in intact adult female rats.

  1993cited by this paper
• Characterization of the human cyclophilin gene and of related processed pseudogenes.

  1990cited by this paper
• Weight-related changes in reproduction function.

  1987cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter.

  1984influential reference
• Functional studies of aromatase activity in human granulosa cells from normal and polycystic ovaries.

  1979cited by this paper
• Population, food intake, and fertility. There is historical evidence for a direct effect of nutrition on reproductive ability.

  1978cited by this paper
• Population, Food Intake, and Fertility

  1978cited by this paper
• Menstrual Cycles: Fatness as a Determinant of Minimum Weight for Height Necessary for Their Maintenance or Onset

  1974cited by this paper
• Obese, a new mutation in the house mouse.

  1950cited by this paper
• Obese, a new mutation in the house mouse.

  1950cited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Serum Leptin Concentrations in Women with Polycystic Ovary Syndrome

  year unknowncited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Serum Leptin Levels in Women with Polycystic Ovary Syndrome: The Role of Insulin Resistance/

  year unknowncited by this paper
• Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Leptin Concentrations in the Polycystic Ovary Syndrome*

  year unknowncited by this paper

• The role of leptin in mammalian oocyte developmental competence and pre-implantation embryo development.

  2025cites this paper
• Sex Differences in Leptin Levels in Children and Adolescents with Normal Weight and Overweight/Obesity Across Pubertal Stages: A Systematic Review and Meta-analysis

  2025cites this paper
• A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons

  2025cites this paper
• The role of asprosin in regulating ovarian granulosa- and theca-cell steroidogenesis: a review with comparisons to other adipokines.

  2024cites this paper
• Granulosa Cells: Central Regulators of Female Fertility

  2024cites this paper
• Роль лептина в развитии патологии эндометрия: литературный обзор

  2024cites this paper
• Understanding polycystic ovary syndrome in light of associated key genes

  2023cites this paper
• Metabolic hormones are integral regulators of female reproductive health and function

  2023cites this paper
• Biology and significance of leptin in animal production: A perspective

  2023cites this paper
• Clinical changes of leptin/ghrelin and PAI-1 levels in adolescent girls with abnormal uterine bleeding-ovulatory dysfunction

  2022cites this paper
• Role of adipokines in the ovarian function: oogenesis and steroidogenesis.

  2021cites this paper
• Possible Role of Leptin in Atopic Dermatitis: A Literature Review

  2021cites this paper
• The relation between obesity, kisspeptin, leptin, and male fertility

  2021cites this paper
• Trajectory of leptin and leptin receptor in vertebrates: Structure, function and their regulation.

  2021cites this paper
• Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome

  2021cites this paper
• Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome.

  2021cites this paper
• Peripheral versus central insulin and leptin resistance: Role in metabolic disorders, cognition, and neuropsychiatric diseases.

  2021cites this paper
• Current Knowledge on the Multifactorial Regulation of Corpora Lutea Lifespan: The Rabbit Model

  2021cites this paper
• Post-Transcriptional Regulation of Gnrhr: A Checkpoint for Metabolic Control of Female Reproduction

  2021cites this paper
• Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers

  2021cites this paper
• Associations of Obesity with Linear Growth and Puberty

  2021cites this paper
• The follicular levels of adipokines and their ratio as the prognostic markers of in vitro fertilization outcomes

  2021cites this paper
• The Importance of Leptin to Reproduction.

  2020cites this paper
• The Role of the Adipokines in the Most Common Gestational Complications

  2020cites this paper
• Inactivation of AMPK alpha 1 Induces Asthenozoospermia and Alters Spermatozoa Morphology

  2020cites this paper
• Effect of supplementing additives in leptin-enriched maturation medium during in vitro maturation and vitrification of goat oocytes

  2020cites this paper
• Leptin role in reproductive system regulation and its perspectives in assisted reproductive technologies

  2020cites this paper
• Leptin and Gestational Diabetes Mellitus

  2020cites this paper
• Salt Inducible Kinases Are Critical Determinants of Female Fertility.

  2020cites this paper
• Роль лептина в регуляции репродуктивной системы и перспективы его использования во вспомогательных репродуктивных технологиях

  2020cites this paper
• Localization and quantification of leptin and leptin receptor in the canine corpus luteum , placenta and uterus during pregnancy

  2019cites this paper
• Relationships between eating disorder psychopathology, sexual hormones and sexual behaviours.

  2019cites this paper
• Computational and artificial neural network based study of functional SNPs of human LEPR protein associated with reproductive function

  2019cites this paper
• Effects of Follicular Fluid Components on Oocyte Maturation and Embryo Development In vivo and In vitro

  2019cites this paper
• Leptin in sperm analysis can be a new indicator.

  2019cites this paper
• Glucoregulatory actions of leptin in rodent models of diabetes

  2019cites this paper
• Obesity as a Risk Factor for Alzheimer’s Disease: Implication of Leptin and Glutamate

  2019cites this paper
• МОЛЕКУЛЯРНЫЕ МЕХАНИЗМЫ ДЕЙСТВИЯ ЛЕПТИНА НА ГИПОТАЛАМО-ГИПОФИЗАРНО-ГОНАДНУЮ ОСЬ, "Цитология"

  2018cites this paper
• Hormones Rule the Roost: Hormonal Influences on Sex Ratio Adjustment in Birds and Mammals

  2018cites this paper
• The role of peptidases in (in) fertility

  2018cites this paper
• Expression of leptin and leptin receptor transcript in ovine corpus luteum

  2018cites this paper
• Physiological predictors of leptin vary during menses and ovulation in healthy women.

  2018cites this paper
• Fertility in classical galactosaemia, a study of N-glycan, hormonal and inflammatory gene interactions

  2018cites this paper
• Role of Leptin in Reproduction

  2017cites this paper
• Leptin Immunohistochemical Staining in the Porcine Ovary

  2017cites this paper
• Putative Effects of Obesity on Linear Growth and Puberty


  2017cites this paper
• Evaluation of Blood Levels of Leptin Hormone before and after the Treatment with Metformin

  2017cites this paper
• Leptin action in normal and pathological pregnancies

  2017cites this paper
• Uterine artery leptin receptors during the ovarian cycle and pregnancy regulate angiogenesis in ovine uterine artery endothelial cells

  2017cites this paper
• The Effect of Leptin on Luteal Angiogenic Factors in the Developing Porcine Corpus Luteum

  2017cites this paper
• Determination of KISS1, KISS1R and Kisspeptin in Fat Tissue of Normal Weight and Obese Humans and Correlations between Serum Kisspeptin and Leptin

  2017cites this paper
• LEPTIN, THE MEDIATOR OF ENERGY RESERVE HAS ROLE IN FERTILITY: A REVIEW

  2017cites this paper
• Erratum: Uterine artery leptin receptors during the ovarian cycle and pregnancy regulate angiogenesis in ovine uterine artery endothelial cells

  2017cites this paper
• The Effect of Leptin on the Hypothalamic-Pituitary Gonadal Axis and Puberty

  2017cites this paper
• The role of stress in PCOS

  2017cites this paper
• Superactive human leptin antagonist (SHLA), triple Lan1 and quadruple Lan2 leptin mutein as a promising treatment for human folliculoma

  2017cites this paper
• Leptin-like immunoreactivity in the central nervous system, digestive organs, and gonads of the giant freshwater prawn, Macrobrachium rosenbergii.

  2017cites this paper
• Obesity and Female Fertility: The Bridging Role of Leptin

  2017cites this paper
• Adipokines as metabolic modulators of ovarian functions in livestock: A mini-review -

  2016cites this paper
• The Deep Correlation between Energy Metabolism and Reproduction: A View on the Effects of Nutrition for Women Fertility

  2016cites this paper
• Sexuality in eating disorders patients: etiological factors, sexual dysfunction and identity issues. A systematic review

  2016cites this paper
• Leptin and body mass index in polycystic ovary syndrome

  2016cites this paper
• The physiology of functional hypothalamic amenorrhea associated with energy deficiency in exercising women and in women with anorexia nervosa

  2016cites this paper
• The role of leptin in the pathogenesis of ovarian insufficiency in obesity women

  2016cites this paper
• Investigating impacts of altered central metabolism on ovarian function

  2016cites this paper
• Effect of leptin on in vitro development of ovine preantral ovarian follicles.

  2016cites this paper
• Effects of Metformin on Serum Levels of Secreted Klotho and Leptin in PCOS Women

  2016cites this paper
• Modulatory role of leptin on ovarian functions in water buffalo (Bubalus bubalis).

  2016cites this paper
• Investigating the Relationship between Serum Leptin levels and Insulin Resistance in Poly Cystic Ovary Syndrome (PCOS) Patients

  2016cites this paper
• Maternal High-Fat Diet-Induced Loss of Fetal Oocytes Is Associated with Compromised Follicle Growth in Adult Rat Offspring

  2016cites this paper
• Leptin and its potential interest in assisted reproduction cycles.

  2016cites this paper
• Leptin-Induced CART (Cocaine- and Amphetamine-Regulated Transcript) Is a Novel Intraovarian Mediator of Obesity-Related Infertility in Females.

  2016cites this paper
• Regulation of the ovarian oxidative status by leptin during the ovulatory process in rats.

  2015cites this paper
• Leptin’s role in oral physiology and physiopathology.

  2015cites this paper
• Genetic analysis and cAMP measurement: comparison between lean and obese anovulating mice.

  2015cites this paper
• Papel de la leptina en la fisiología y fisiopatología oral

  2015cites this paper
• THE EFFECTS OF LEPTIN ON PREGNANCY AND NEONATAL OUTCOME, A REVIEW

  2015influential citation
• Direct effects of leptin and adiponectin on peripheral reproductive tissues: a critical review.

  2015cites this paper
• Immunohistochemical Evaluation of Leptin Role in Skin Tags

  2015cites this paper
• The importance of gastrointestinal hormones in the development of obesity-related hypertension

  2015cites this paper
• Leptin gene polymorphism in Lohi, Kajli and Spili breeds of sheep.

  2015cites this paper
• Roles of leptin in reproduction, pregnancy and polycystic ovary syndrome: consensus knowledge and recent developments.

  2015cites this paper
• Duplicated Leptin Receptors in Two Species of Eel Bring New Insights into the Evolution of the Leptin System in Vertebrates

  2015cites this paper
• Hormonal State Comparison (Progesterone, Estradiol, and Leptin) of Body Fat and Body Mass Indices in Mexican Women as a Risk Factor for Neonatal Physiologic Condition.

  2015cites this paper
• Role of Leptin in Growth, Reproduction and Milk Production in Farm Animals: A Review

  2015cites this paper
• Role of leptin in female reproduction

  2015cites this paper
• fat, reproductive, nutritional, and endocrine factors Plasma leptin in female athletes: relationship with body

  2015cites this paper
• Neuropeptide Y regulates the leptin receptors in rat hypothalamic and pituitary explant cultures.

  2014cites this paper
• Assessment of follicular fluid leptin levels and insulin resistance as outcome predictors in women undergoing in vitro fertilization-intracytoplasmic sperm injection.

  2014cites this paper
• Mouse models to study polycystic ovary syndrome: a possible link between metabolism and ovarian function?

  2014cites this paper
• Gestational carrier BMI and reproductive, fetal and neonatal outcomes: are the risks the same with increasing obesity?

  2014cites this paper
• Role of leptin in the regulation of sterol/steroid biosynthesis in goose granulosa cells.

  2014cites this paper
• An updated view of leptin on implantation and pregnancy: a review.

  2014cites this paper
• Opposing Roles of Leptin and Ghrelin in the Equine Corpus Luteum Regulation: An In Vitro Study

  2014cites this paper
• The effect of leptin on luteal angiogenic factors during the luteal phase of the estrous cycle in goats.

  2014cites this paper
• Leptin : A Metabolic Regulator of Reproduction in Livestock

  2014cites this paper
• The effect of Ramadan fasting on LH, FSH, oestrogen, progesterone and leptin in pregnant women

  2014cites this paper
• Effect of Leptin Supplementation in Maturation Medium on in vitro Nuclear Maturation and Fertilization of Camel Oocytes (Camelus dromedarius)

  2014cites this paper
• Serum leptin level in obese women with polycystic ovary syndrome, and its relation to insulin resistance

  2014cites this paper
• Association between obesity and sexual maturation in Chinese children: a muticenter study

  2014cites this paper