The numbers of limb motor neurons in the human lumbosacral cord throughout life.

No abstract is available for this paper.

• Publication year

  1977

• Venue

  Journal of Neurological Sciences

• Publication date

  1977-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0022-510X(77)90069-7PMID 925710
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The numbers of limb motor neurones in the individual segments of the human lumbosacral spinal cord.

  1974cited by this paper
• Total numbers of limb motor neurones in the human lumbosacral cord and an analysis of the accuracy of various sampling procedures.

  1973cited by this paper
• Histochemical aspects of five limb muscles in old age. An autopsy study.

  1971cited by this paper
• Quantitative methods in histology.

  1970cited by this paper
• GOWER'S TRACT AND SPINAL BORDER CELLS

  1940cited by this paper

• Ageing of human myofibres in the Vastus Lateralis muscle: a narrative review.

  2026cites this paper
• Tongue Blade Neuromuscular Junction Defects in Old F344 Rats.

  2026cites this paper
• Nerve, muscle and adiposity: Associations with gait speed across adulthood in the Baltimore Longitudinal Study of Aging.

  2026cites this paper
• Structural and mitochondrial dendritic degenerations in old hypoglossal motor neurons.

  2026cites this paper
• Leg-specific modulation of muscle synergies during Tai Chi heel kick in elite athletes

  2026cites this paper
• Episodic denervation as a driver of loss of skeletal muscle redox homeostasis and muscle weakness in sarcopenia: Possible amelioration by exercise

  2025cites this paper
• Redox-regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age-related muscle weakness.

  2025cites this paper
• Motor performance and aging in males and females.

  2025cites this paper
• Neural Cues and Genomic Clues: NGS Insights into Neurogenic Sarcopenia and Muscle Atrophy

  2025cites this paper
• Performance fatigability on a constant-load dynamic task is greater in females with moderate-severity Parkinson's disease than healthy-aging controls.

  2025cites this paper
• On the concept of ‘mild motor impairment’: A neuromotor harbinger of sarcopenia and frailty?

  2025cites this paper
• Dendritic alterations precede age‐related dysphagia and nucleus ambiguus motor neuron death

  2025cites this paper
• Grasp-Dependent Modulations in EEG-EMG Coherence Are Observed in Young but Not Older Adults

  2025cites this paper
• Age-related changes and lack of effect of midlife resistance wheel exercise on afferent connectivity of lumbar alpha motor neurons in ageing mouse spinal cord

  2025cites this paper
• The decision support system for preventing non-elderly sarcopenia: data from NHANES 2011-2018

  2025cites this paper
• Exploration of the effects of Tai Chi practice on lower limb corticomuscular coherence during balance-demanding virtual reality conditions in older adults

  2025cites this paper
• Muscle spindle afferent neurons preferentially degenerate with aging

  2025cites this paper
• Intracellular and Extracellular Redox Signals During Exercise and Aging.

  2025cites this paper
• Mechanisms of Biological Aging with Special Reference to the Skeletal Muscle.

  2025cites this paper
• Exercise Strategies for Parkinson Disease Management

  2025cites this paper
• Systematic review of mitochondrial dysfunction and oxidative stress in aging: A focus on neuromuscular junctions

  2025cites this paper
• Klotho Deficiency Promotes Skeletal Muscle Weakness and Is Associated with Impaired Motor Unit Connectivity

  2025cites this paper
• Diaphragm Muscle: A Pump That Can Not Fail.

  2025cites this paper
• Unacylated Ghrelin Protects Against Age‐Related Loss of Muscle Mass and Contractile Dysfunction in Skeletal Muscle

  2024cites this paper
• Age-related increase in the excitability of mouse layer V pyramidal neurons in the primary motor cortex is accompanied by an increased persistent inward current

  2024cites this paper
• Common synaptic inputs and persistent inward currents of vastus lateralis motor units are reduced in older male adults

  2024cites this paper
• Neurological Aspects of Sarcopenia: A Comprehensive Update on Pathophysiology, Diagnosis, and Therapeutic Advances

  2024cites this paper
• Molecular hallmarks of ageing in amyotrophic lateral sclerosis

  2024cites this paper
• Autophagy markers LC3 and p62 in aging lumbar motor neurons

  2024cites this paper
• Incidence and mortality of ALS: a 42-year population-based nationwide study

  2024cites this paper
• Spinal maps of motoneuron activity during human locomotion: neuromechanical considerations

  2024cites this paper
• Morphometric analysis of spinal motor neuron degeneration in sporadic amyotrophic lateral sclerosis.

  2024cites this paper
• Cortical and spinal responses to short-term strength training and detraining in young and older adults in rectus femoris muscle

  2024cites this paper
• Ageing leads to selective type II myofibre deterioration and denervation independent of reinnervative capacity in human skeletal muscle

  2024cites this paper
• Muscle fibroblasts and stem cells stimulate motor neurons in an age and exercise‐dependent manner

  2024cites this paper
• Differences in muscle activity of extrinsic and intrinsic foot muscles in toe grip and push-down movements of the great toe.

  2024cites this paper
• The role of physical activity in mitigating age-related changes in the neuromuscular control of gait

  2024cites this paper
• Delayed neuromuscular fatigue recovery unveils reduced fatigue tolerance in elderly following maximal intermittent exercise

  2024cites this paper
• Deletion of Sod1 in Motor Neurons Exacerbates Age-Related Changes in Axons and Neuromuscular Junctions in Mice

  2023cites this paper
• Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men

  2023cites this paper
• Revisiting specific force loss in human permeabilized single skeletal muscle fibers obtained from older individuals

  2023cites this paper
• Pathogenesis, Intervention, and Current Status of Drug Development for Sarcopenia: A Review

  2023cites this paper
• Muscle power-related parameters in middle-aged and older Brazilian women: a cross-sectional study

  2023cites this paper
• Age‐related differences in the neuromuscular performance of fatigue‐provoking exercise under severe whole‐body hyperthermia conditions

  2023cites this paper
• Sarcopenia of the longitudinal tongue muscles in rats.

  2023cites this paper
• Exercise Interventions for the Management of Sarcopenia: Possibilities and Challenges

  2023cites this paper
• Sex‐ and age‐specific normative values of lower extremity muscle power in Italian community‐dwellers

  2023cites this paper
• Loss of larger hypoglossal motor neurons in aged Fischer 344 rats.

  2023cites this paper
• Regional recruitment and differential behaviour of motor units during postural control in older adults.

  2023cites this paper
• A Computer Interface Controlled by Upper Limb Muscles: Effects of a Two Weeks Training on Younger and Older Adults

  2023cites this paper
• Plantar intrinsic foot muscle activation during functional exercises compared to isolated foot exercises in younger adults

  2023cites this paper
• Modification of the locomotor pattern when deviating from the characteristic heel-to-toe rolling pattern during walking

  2023cites this paper
• Human motor neurons are rare and can be transcriptomically divided into known subtypes

  2023cites this paper
• Aging affects the number and morphological heterogeneity of rat phrenic motor neurons and phrenic motor axons

  2023cites this paper
• Muscle fiber type grouping does not change in response to prolonged resistance exercise training in healthy older men.

  2023cites this paper
• Deletion of quinolinate phosphoribosyltransferase gene accelerates frailty phenotypes and neuromuscular decline with aging in a sex‐specific pattern

  2023cites this paper
• Neuromuscular Dysfunction Precedes Cognitive Impairment in a Mouse Model of Alzheimer’s Disease

  2023cites this paper
• The Brain and Spinal Microvasculature in Normal Aging.

  2023cites this paper
• Aging alters mechanisms underlying voluntary movements in spinal motor neurons of mice, primates, and humans

  2023cites this paper
• Bioenergetic Evaluation of Muscle Fatigue in Murine Tongue

  2022cites this paper
• Acylated Ghrelin Receptor Agonist HM01 Decreases Lean Body and Muscle Mass, but Unacylated Ghrelin Protects against Redox-Dependent Sarcopenia

  2022cites this paper
• Structure and Function of the Mammalian Neuromuscular Junction.

  2022cites this paper
• Homeostatic changes maintain the gain control of spinal motoneurones across the lifetime of C57BL/6J mice

  2022cites this paper
• Human skeletal muscle acetylcholine receptor gene expression in elderly males performing heavy resistance exercise.

  2022cites this paper
• Changes in neuromuscular function in elders: Novel techniques for assessment of motor unit loss and motor unit remodeling with aging.

  2022cites this paper
• Enhancing Locomotor Learning With Transcutaneous Spinal Electrical Stimulation and Somatosensory Augmentation: A Pilot Randomized Controlled Trial in Older Adults

  2022cites this paper
• Reinnervation of Vastus lateralis is increased significantly in seniors (70-years old) with a lifelong history of high-level exercise (2013, revisited here in 2022)

  2022cites this paper
• Pharmacologic treatment with OKN-007 reduces alpha-motor neuron loss in spinal cord of aging mice

  2022cites this paper
• Redox Control of Signalling Responses to Contractile Activity and Ageing in Skeletal Muscle

  2022cites this paper
• Evaluation of Spatiotemporal Patterns of the Spinal Muscle Coordination Output during Walking in the Exoskeleton

  2022cites this paper
• Deletion of Sod1 in motor neurons exacerbates age-related changes in axons and NMJs associated with premature muscle atrophy in aging mice

  2022cites this paper
• DO MOTONEURON DISCHARGE RATES SLOW WITH AGING? A SYSTEMATIC REVIEW AND META-ANALYSIS.

  2022cites this paper
• Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia

  2022cites this paper
• Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise

  2022influential citation
• Motor unit firing rates during constant isometric contraction: establishing and comparing an age-related pattern among muscles.

  2021cites this paper
• Age-related changes in upper limb coordination in a complex reaching task

  2021cites this paper
• Older adults use a motor plan that is detrimental to endpoint control

  2021cites this paper
• Skeletal Development During the First Three Decades in Life

  2021cites this paper
• Characteristics of the Electrophysiological Properties of Neuromuscular Motor Units and Its Adaptive Strategy Response in Lower Extremity Muscles for Seniors with Pre-Sarcopenia: A Preliminary Study

  2021cites this paper
• Terminal Schwann Cell Aging: Implications for Age-Associated Neuromuscular Dysfunction

  2021cites this paper
• Assessment of functional sit-to-stand muscle power: Cross-sectional trajectories across the lifespan.

  2021cites this paper
• Ipsilateral Motor Evoked Potentials as a Measure of the Reticulospinal Tract in Age-Related Strength Changes

  2021cites this paper
• DO MOTONEURONS’ DISCHARGE RATE SLOW WITH AGING? A SYSTEMATIC REVIEW AND META-ANALYSIS

  2021cites this paper
• The Influence of Motor Unit Number and Muscle Activation on Early Phase Rate of Torque Development in Younger and Older Men

  2021cites this paper
• Effect of Caloric Restriction on Aging: Fixing the Problems of Nutrient Sensing in Postmitotic Cells?

  2021cites this paper
• Variation in muscle and neuromuscular junction morphology between atrophy-resistant and atrophy-prone muscles supports failed re-innervation in aging muscle atrophy.

  2021cites this paper
• Voluntary wheel running with and without follistatin overexpression improves NMJ transmission but not motor unit loss in late life of C57BL/6J mice.

  2021cites this paper
• Deletion of Neuronal CuZnSOD Accelerates Age-Associated Muscle Mitochondria and Calcium Handling Dysfunction That Is Independent of Denervation and Precedes Sarcopenia

  2021cites this paper
• The role of the neuromuscular junction in sarcopenia

  2021cites this paper
• Neuromuscular Age-Related Adjustment of Gait When Moving Upwards and Downwards

  2021cites this paper
• Age-related changes in the neuromuscular control of forward and backward locomotion.

  2021cites this paper
• Linking mitochondrial dysfunction to sarcopenia

  2021cites this paper
• Motor Unit Remodeling

  2021cites this paper
• From mitochondria to sarcopenia: Role of inflammaging and RAGE-ligand axis implication.

  2021cites this paper
• Anconeus motor unit firing rates during isometric and muscle shortening contraction comparing young and very old adults.

  2021cites this paper
• Shared and Distinct Mechanisms of Skeletal Muscle Atrophy: A Narrative Review.

  2021cites this paper
• Sarcopenia versus cancer cachexia: the muscle wasting continuum in healthy and diseased aging

  2021cites this paper
• Flexible Corticospinal Control of Muscles

  2021cites this paper
• Natural Compounds Attenuate Denervation-Induced Skeletal Muscle Atrophy

  2021cites this paper
• The Impact of Milk Fat Globule Membrane with Exercise on Age-Related Degeneration of Neuromuscular Junctions

  2021cites this paper