Platelet function analyzer (PFA)‐100® closure time in the evaluation of platelet disorders and platelet function

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Thrombosis and Haemostasis

• Publication date

  2006-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1538-7836.2006.01771.xPMID 16420557
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Willebrand disease].

  2006cited by this paper
• Duration of increased bleeding tendency after cessation of aspirin therapy.

  2005cited by this paper
• Platelet dysfunction in primary thrombocythemia using the platelet function analyzer, PFA-100.

  2005cited by this paper
• Monitoring of clopidogrel action: comparison of methods.

  2005cited by this paper
• The role of PFA‐100® testing in the investigation and management of haemostatic defects in children and adults

  2005cited by this paper
• Brief Communication: Duration of Platelet Dysfunction after a 7-Day Course of Ibuprofen

  2005cited by this paper
• Aspirin resistance: position paper of the Working Group on Aspirin Resistance

  2005cited by this paper
• The effect of a pneumatic tube transport system on PFA‐100™ closure time and whole blood platelet aggregation

  2004cited by this paper
• Time lag in platelet function inhibition by clopidogrel in stroke patients as measured by PFA‐100

  2004cited by this paper
• Platelet Function Predicts Myocardial Damage in Patients With Acute Myocardial Infarction

  2004cited by this paper
• Platelet function testing to assess the effectiveness of platelet transfusion therapy.

  2004cited by this paper
• A Practical Concept for Preoperative Identification of Patients with Impaired Primary Hemostasis

  2004cited by this paper
• In vitro aspirin resistance detected by PFA‐100TM closure time: pivotal role of plasma von Willebrand factor

  2004cited by this paper
• Aspirin and Clopidogrel: Efficacy, Safety, and the Issue of Drug Resistance

  2004cited by this paper
• Template bleeding time and PFA‐100® have low sensitivity to screen patients with hereditary mucocutaneous hemorrhages: comparative study in 148 patients

  2004cited by this paper
• Variable inhibition of high-shear-induced platelet plug formation by eptifibatide and tirofiban under conditions of platelet activation and high von Willebrand release: a randomized, placebo-controlled, clinical trial.

  2004cited by this paper
• The effect of a pneumatic tube transport system on PFA-100 trade mark closure time and whole blood platelet aggregation.

  2004cited by this paper
• Platelet function testing to assess effectiveness of platelet transfusion therapy.

  2004cited by this paper
• Are the bleeding time and PFA‐100® useful in the initial screening of patients with mucocutaneous bleedings of hereditary nature?

  2004cited by this paper
• Antiplatelet Effect of Aspirin in Patients With Cerebrovascular Disease

  2003cited by this paper
• A comparison of the effects of aspirin on bleeding time measured using the Simplate method and closure time measured using the PFA-100, in healthy volunteers.

  2003cited by this paper
• Synergistic antiplatelet effects of clopidogrel and aspirin detected with the PFA-100 in stroke patients.

  2003cited by this paper
• Monitoring aspirin 100 mg and clopidogrel 75 mg therapy with the PFA-100 device in patients with peripheral arterial disease.

  2003cited by this paper
• The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression.

  2003cited by this paper
• Relation Between Platelet Response to Exercise and Coronary Angiographic Findings in Patients With Effort Angina

  2003cited by this paper
• Comparison of PFA-100 testing and bleeding time for detecting platelet hypofunction and von Willebrand disease in clinical practice

  2003cited by this paper
• Platelet Function Under Aspirin, Clopidogrel, and Both After Ischemic Stroke: A Case-Crossover Study

  2003cited by this paper
• Comparison of PFA-100 and Bleeding Time Testing in Pediatric Patients With Suspected Hemorrhagic Problems

  2003cited by this paper
• The role of the platelet function analyser (PFA‐100TM) in the characterization of patients with von Willebrand's disease and its relationships with von Willebrand factor and the ABO blood group

  2003cited by this paper
• Platelet function under aspirin, clopidogrel, and both after ischemic stroke: a case-crossover study.

  2003cited by this paper
• Desmopressin antagonizes the in vitro platelet dysfunction induced by GPIIb/IIIa inhibitors and aspirin.

  2003cited by this paper
• GPVI levels in platelets: relationship to platelet function at high shear.

  2003cited by this paper
• Sebastian platelet syndrome: a hereditary macrothrombocytopenia.

  2003cited by this paper
• Effect of fibrinogen concentration and platelet count on the inhibitory effect of abciximab and tirofiban

  2003cited by this paper
• Acquired von Willebrand syndrome in aortic stenosis.

  2003cited by this paper
• Monitoring Aspirin 1 00 mg and Clopidogrel 75 mg Therapy with the PFA-1 00 Device in Patients with Peripheral Arterial Disease

  2003cited by this paper
• Clinical application of the PFA-100®

  2002cited by this paper
• Evaluation of a Platelet Function Analyser (PFA-100) in patients with a bleeding tendency.

  2002cited by this paper
• Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate.

  2002cited by this paper
• Platelet function rather than plasmatic coagulation explains hypercoagulable state in cholestatic liver disease.

  2002cited by this paper
• Aspirin non-responsiveness as measured by PFA-100 in patients with coronary artery disease.

  2002cited by this paper
• Comparison between nasal and intravenous desmopressin for the treatment of aminosalicylic acid-induced platelet dysfunction

  2002cited by this paper
• Effect of low-molecular weight dextran sulfate on coagulation and platelet function tests.

  2002cited by this paper
• The PFA-100: a potential rapid screening tool for the assessment of platelet dysfunction.

  2002cited by this paper
• High-dose aspirin in addition to daily low-dose aspirin decreases platelet activation in patients before and after percutaneous coronary intervention.

  2002cited by this paper
• The effects of flavanol-rich cocoa and aspirin on ex vivo platelet function.

  2002cited by this paper
• Hermansky–Pudlak syndrome: infrequent bleeding and first report of Turkish and Pakistani kindreds

  2002cited by this paper
• Evaluation of the PFA-100 system for monitoring desmopressin therapy in patients with type 1 von Willebrand's disease.

  2002cited by this paper
• Assessment of thrombocytopenic disorders using the Platelet Function Analyzer (PFA‐100®) *

  2002cited by this paper
• Effect of aspirin treatment in patients with peripheral arterial disease monitored with the platelet function analyzer PFA-100

  2002cited by this paper
• Determination of platelet aggregation inhibition during percutaneous coronary intervention with the platelet function analyzer PFA-100.

  2002cited by this paper
• The Effects of Perioperatively Administered Colloids and Crystalloids on Primary Platelet-Mediated Hemostasis and Clot Formation

  2002cited by this paper
• Profile and prevalence of aspirin resistance in patients with cardiovascular disease.

  2001cited by this paper
• Impact of plasmapheresis on platelet hemostatic capacity in healthy voluntary blood donors detected by the platelet function analyzer PFA-100™

  2001cited by this paper
• Influence of ABO blood groups on primary hemostasis

  2001cited by this paper
• Detecting aspirin resistance with the platelet function analyzer (PFA-100).

  2001cited by this paper
• Impact of plasmapheresis on platelet hemostatic capacity in healthy voluntary blood donors detected by the platelet function analyzer PFA-100.

  2001cited by this paper
• Platelet function analyzer (PFA-100): a tool to quantify congenital or acquired platelet dysfunction.

  2001cited by this paper
• Rapid assessment of glycoprotein IIb/IIIa blockade with the platelet function analyzer (PFA-100) during percutaneous coronary intervention.

  2001cited by this paper
• Utility of the PFA‐100® for assessing bleeding disorders and monitoring therapy: a review of analytical variables, benefits and limitations

  2001cited by this paper
• Evaluation of primary hemostasis in neonates with a new in vitro platelet function analyzer.

  2001cited by this paper
• Impaired Platelet Function among Platelet Donors

  2001cited by this paper
• Influence of the ABO Blood Type on the Platelet Function Analyzer PFA-100

  2001cited by this paper
• Reassessment of the Correlation between the von Willebrand Factor Activity, the PFA-100®, and the Bleeding Time in Patients with von Willebrand Disease

  2001cited by this paper
• Laboratory diagnosis of von Willebrand disorder (vWD) and monitoring of DDAVP therapy: efficacy of the PFA‐100® and vWF:CBA as combined diagnostic strategies

  2001cited by this paper
• Diurnal variation in platelet aggregation iwth the PFA-100 platelet function analyser.

  2000cited by this paper
• von Willebrand Factor Ristocetin Cofactor Activity Correlates with Platelet Function in a High Shear Stress System

  2000cited by this paper
• Paroxetine decreases platelet serotonin storage and platelet function in human beings

  2000cited by this paper
• Monitoring of Aspirin (ASA) Pharmacodynamics with the Platelet Function Analyzer PFA-100®

  2000cited by this paper
• [High-shear force-induced platelet aggregation in the screening and diagnosis of von Willebrand disease].

  2000cited by this paper
• A Study of Platelet Functions with a New Analyzer Using High Shear Stress (PFA100™) in Patients Undergoing Coronary Artery Bypass Graft

  2000cited by this paper
• Platelet function analysis with PFA-100 in patients medicated with acetylsalicylic acid strongly depends on concentration of sodium citrate used for anticoagulation of blood sample.

  2000cited by this paper
• Diurnal variation in platelet aggregation with the PFA–100 platelet function analyser

  2000cited by this paper
• Assessment of Primary Hemostasis by PFA-100® Analysis in a Tertiary Care Center

  2000cited by this paper
• Use of the PFA-100™ Apparatus to Assess Platelet Function in Patients Undergoing PTCA during and after Infusion of cE3 Fab in the Presence of other Antiplatelet Agents

  2000cited by this paper
• The Platelet Function Analyzer (PFA-100) may not be suitable for monitoring the therapeutic efficiency of von Willebrand concentrate in type III von Willebrand disease

  1999cited by this paper
• Comparison of PFA-100 closure time and template bleeding time of patients with inherited disorders causing defective platelet function.

  1999cited by this paper
• Use of a novel platelet function analyzer (PFA‐100™) with high sensitivity to disturbances in von willebrand factor to screen for von willebrand's disease and other disorders

  1999cited by this paper
• Performance of the platelet function analyser PFA-100 in testing abnormalities of primary haemostasis.

  1999cited by this paper
• Meloxicam, 15 mg/day, spares platelet function in healthy volunteers

  1999cited by this paper
• Evaluation of acquired platelet dysfunctions in uremic and cirrhotic patients using the platelet function analyzer (PFA-100 ): influence of hematocrit elevation.

  1999cited by this paper
• A simple assay for platelet-mediated hemostasis in flowing whole blood (PFA-100): reproducibility and effects of sex and age.

  1999cited by this paper
• Genetic Risk Factors for Superficial Vein Thrombosis

  1999cited by this paper
• Low Platelet 2β1 Levels in Type I von Willebrand Disease Correlate With Impaired Platelet Function in a High Shear Stress System

  1999cited by this paper
• Evaluation of platelet function with the PFA-100 system in patients with congenital defects of platelet secretion.

  1999cited by this paper
• Inhibition of platelet aggregation after intake of acetylsalicylic acid detected by a platelet function analyzer (PFA-100).

  1999cited by this paper
• State-of-the-Art Review : The Effect of Antiplatelet Drugs, Heparin, and Preanalytical Variables on Platelet Function Detected by the Platelet Function Analyzer (PFA-100®)

  1999cited by this paper
• Therapeutic monitoring of von Willebrand disease: interest and limits of a platelet function analyser at high shear rates

  1999cited by this paper
• Low platelet alpha2beta1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system.

  1999cited by this paper
• Standardization of the PFA‐100® platelet function test in 105 mmol/l buffered citrate: effect of gender, smoking, and oral contraceptives

  1999cited by this paper
• Evaluation of the PFA-100® System in the Diagnosis and Therapeutic Monitoring of Patients with von Willebrand Disease

  1999cited by this paper
• Ultrastructural analysis of the distribution of von Willebrand factor and fibrinogen in platelet aggregates formed in the PFA-100.

  1998cited by this paper
• Screening for von Willebrand disease with a new analyzer using high shear stress: a study of 60 cases.

  1998cited by this paper
• Use of the PFA-100® in the Assessment of Primary, Platelet-Related Hemostasis in a Pediatric Setting

  1998cited by this paper
• PFA-100™ System: A New Method for Assessment of Platelet Dysfunction

  1998cited by this paper
• The Platelet Function Analyzer (PFA‐100®): a novel in‐vitro system for evaluation of primary haemostasis in children

  1998cited by this paper
• Comparison of four commercial citrate blood collection systems for platelet function analysis by the PFA-100 system.

  1997cited by this paper
• Characterization of an In Vitro Platelet Function Analyzer, PFA-100™

  1996cited by this paper
• Antigen Generation in Heparin-Associated Thrombocytopenia: The Nonimmunologic Type and the Immunologic Type Are Closely Linked in Their Pathogenesis

  1995cited by this paper
• Description of an In Vitro Platelet Function Analyzer-PFA-100™

  1995cited by this paper

• Recent advances in point-of-care testing devices for transfusion medicine

  2026cites this paper
• Diagnosis of Inherited Platelet Disorders: Clinical Evaluation and Functional and Molecular Assays

  2025cites this paper
• The effect of testosterone on platelet activation and inflammation in transgender men

  2025cites this paper
• Automation in Platelet Function Testing: Current Challenges and Future Directions

  2025cites this paper
• Platelet function analyzer (PFA-100) in patients with mild to moderate bleeding disorders and bleeding disorder of unknown cause.

  2025cites this paper
• Is primary hemostasis involved in bleeding diathesis in patients with type 1 glycogen storage disease?

  2025cites this paper
• The diagnostic value of the platelet function analyzer in mild to moderate bleeding disorders.

  2025cites this paper
• Platelet activation and inflammation in transgender women using hormone therapy

  2024cites this paper
• Perioperative considerations in the paediatric patient with congenital and acquired coagulopathy

  2024cites this paper
• Randomized Phase I Trial of the α‐Synuclein Antibody Lu AF82422

  2024cites this paper
• Point-of-Care Testing in Patients with Hereditary Disorders of Primary Hemostasis: A Narrative Review

  2024cites this paper
• The Diagnostic Assessment of Inherited Platelet Function Defects - Part 1: An Overview of the Diagnostic Approach and Laboratory Methods

  2024cites this paper
• Guideline for laboratory diagnosis and monitoring of von Willebrand disease: A joint guideline from the United Kingdom Haemophilia Centre Doctors' Organisation and the British Society for Haematology

  2024cites this paper
• Utility of Global Hemostatic Assays in Patients with Bleeding Disorders of Unknown Cause

  2024cites this paper
• Investigation of Bleeding Disorders: When and How Should We Test Platelet Functions?

  2024cites this paper
• The hemostatic profile of cold-stored whole blood from non-greyhound and greyhound dogs over 42 days

  2023cites this paper
• Efficacy and Safety Analysis of Combination Therapy Consisting of Intravenous Immunoglobulin and Corticosteroids versus Respective Monotherapies in the Treatment of Relapsed ITP in Adults

  2023cites this paper
• Testing strategies used in the diagnosis of rare inherited bleeding disorders

  2023cites this paper
• Bleeding Disorder of Unknown Cause: A Diagnosis of Exclusion

  2023cites this paper
• The efficacy of aspirin to inhibit platelet aggregation in patients hospitalised with a severe infection: a multicentre, open-label, randomised controlled trial

  2023cites this paper
• A novel quantitative method to evaluate the contribution of platelet products to white thrombus formation in reconstituted blood under flow conditions

  2023cites this paper
• Understanding clopidogrel resistance: Mechanisms, detections, implications and surmount the clopidogrel resistant in order to potential solutions

  2023cites this paper
• No effect of omega-3 polyunsaturated fatty acid supplementation on inflammatory markers in familial hypercholesterolemia: a randomized crossover trial

  2023cites this paper
• PFA-100 in advanced chronic liver disease: End of the story?

  2023cites this paper
• The prevalence of bleeding disorders in women with proven endometriosis: results of a screening study.

  2023cites this paper
• Platelet function analyzer-200 closure curve analysis and assessment of flow-obstructed samples.

  2023cites this paper
• The evolving knowledge on primary hemostasis in patients with cirrhosis: A comprehensive review

  2023cites this paper
• Towards 50 years of platelet function analyser (PFA) testing

  2022cites this paper
• Multiparameter platelet function analysis of bleeding patients with a prolonged platelet function analyser closure time

  2022cites this paper
• Diagnosing Czech Patients with Inherited Platelet Disorders

  2022cites this paper
• The Pharmacological Effects of Silver Nanoparticles Functionalized with Eptifibatide on Platelets and Endothelial Cells

  2022cites this paper
• Screening and diagnosis of inherited platelet disorders

  2022cites this paper
• Platelet abnormalities in patients with Parkinson's disease undergoing preoperative evaluation for deep brain stimulation

  2022cites this paper
• Platelet function testing: Current practice among clinical centres in Northern Europe

  2022cites this paper
• Diagnostic workup of inherited platelet disorders

  2022cites this paper
• The use of a low-flux hemo-dialyzer is associated with impaired platelet aggregation in patients undergoing chronic hemodialysis

  2022cites this paper
• Advances in the diagnosis of heritable platelet disorders.

  2022cites this paper
• Assay validity of point-of-care platelet function tests in thrombocytopenic blood samples

  2022cites this paper
• Multiplate platelet aggregometry in dogs undergoing laparoscopic liver biopsy for diagnosis of chronic hepatopathy.

  2021cites this paper
• Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet agents at physiological temperature.

  2021cites this paper
• Inherited Platelet Disorders: An Updated Overview

  2021cites this paper
• Platelets

  2021cites this paper
• Diagnostic approach to the patient with a suspected inherited platelet disorder: Who and how to test

  2021cites this paper
• Bleeding and Clotting Disorders

  2021cites this paper
• Heparin's effect on primary hemostasis detected by PFA-200

  2021cites this paper
• Platelet Function Assays for the Diagnosis of Aspirin Resistance

  2021influential citation
• Platelet Phenotyping and Function Testing in Thrombocytopenia

  2021cites this paper
• Establishment of reference intervals for Platelet Function Analyzer -100 closure time in Algerian adults

  2021cites this paper
• Correlation between PlateletWorks® and PFA-100® for Measuring Platelet Function before Urgent Surgery in Patients with Chronic Antiplatelet Therapy

  2021cites this paper
• Platelet Distribution Width Is Associated with P-Selectin Dependent Platelet Function: Results from the Moli-Family Cohort Study

  2021cites this paper
• Comparison of acetylsalicylic acid and clopidogrel non-responsiveness assessed by light transmittance aggregometry and PFA-100® in patients undergoing neuroendovascular procedures

  2020cites this paper
• Scalable manufacture of a disposable, storage-stable eight-channel microfluidic device for rapid testing of platelet, coagulation, and drug function under whole blood flow.

  2020cites this paper
• Cranberry supplementation as a cause of major intraoperative bleeding during vascular surgery due to aspirin-like platelet inhibition.

  2020cites this paper
• Differentiation of Patients with Symptomatic Low von Willebrand Factor from Those with Asymptomatic Low von Willebrand Factor

  2020cites this paper
• Performance evaluation of the Anysis-200 platelet function analyzer in cardiac patients

  2020cites this paper
• Advances in Platelet Function Testing—Light Transmission Aggregometry and Beyond

  2020cites this paper
• The role of platelet function analyzer-200 in predicting perioperative bleeding risk

  2020cites this paper
• Corrigendum to “Patients With Severe Aortic Valve Stenosis and Impaired Platelet Function Benefit From Preoperative Desmopressin Infusion” [Ann Thorac Surg 91 (2011) 1420-1426]

  2020cites this paper
• Diagnostic Challenges in Newborns and Infants with Coagulation Disorders

  2020cites this paper
• Platelet function and microvesicle generation in patients with hemophilia A

  2020cites this paper
• Platelet Function: Meloxicam Intravenous in Whole Blood Samples From Healthy Volunteers

  2020cites this paper
• Disease progression and defects in primary hemostasis as major cause of bleeding in multiple myeloma

  2020cites this paper
• Diagnostic challenges of inherited mild bleeding disorders: a bait for poorly explored clinical and basic research

  2019cites this paper
• Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes

  2019cites this paper
• Antiplatelet Therapy Monitoring

  2019cites this paper
• Platelet functional activity: physiology and laboratory diagnostic methods

  2019cites this paper
• Update on diagnostic testing for platelet function disorders: What is practical and useful?

  2019cites this paper
• Platelet Function Testing in Clinical Research Trials

  2019cites this paper
• Methods for measurement of platelet function in the assessment of nonclinical drug safety and implications for translatability

  2019cites this paper
• Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis

  2019cites this paper
• High-Risk Pregnancies and Their Impact on Neonatal Primary Hemostasis

  2019cites this paper
• Flow Devices to Assess Platelet Function: Historical Evolution and Current Choices

  2019cites this paper
• Fundamentals for a Systematic Approach to Mild and Moderate Inherited Bleeding Disorders: An EHA Consensus Report

  2019cites this paper
• Clinical Tests of Platelet Function

  2019cites this paper
• Platelet function assays in diagnosis: an update

  2019cites this paper
• Функциональная активность тромбоцитов: физиология и методы лабораторной диагностики

  2019cites this paper
• Fundamentals for a Systematic Approach to Mild and Moderate Inherited Bleeding Disorders: A EHA Consensus Report

  2019cites this paper
• Platelet Function Analyzer

  2019cites this paper
• Update in the Investigation of von Willebrand Disease

  2019cites this paper
• Screening for platelet function disorders with Multiplate and platelet function analyzer

  2019cites this paper
• Alteration of von Willebrand Factor after Transcatheter Aortic Valve Replacement in the Absence of Paravalvular Regurgitation

  2018cites this paper
• High-throughput elucidation of thrombus formation reveals sources of platelet function variability

  2018cites this paper
• A Randomized, Placebo‐Controlled, Multiple‐Ascending‐Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Soluble Guanylate Cyclase Stimulator Praliciguat in Healthy Subjects

  2018cites this paper
• Functional Classification of Paediatric Patients with Non-syndromic Delta-Storage Pool Deficiency

  2018cites this paper
• In vitro analysis of platelet function in acute aneurysmal subarachnoid haemorrhage

  2018cites this paper
• University of Birmingham Comparison of nine platelet function tests used to determine responses to different aspirin dosages in people with type 2 Diabetes

  2018cites this paper
• Comparison of nine platelet function tests used to determine responses to different aspirin dosages in people with type 2 diabetes

  2018cites this paper
• Performance and usefulness of platelet aggregation testing

  2018cites this paper
• Platelet aggregation measured by single-platelet counting and using PFA-100 devices

  2018cites this paper
• Laboratory diagnosis of inherited platelet function disorders.

  2018cites this paper
• Von Willebrand factor and the aortic valve: Concepts that are important in the transcatheter aortic valve replacement era.

  2018cites this paper
• Bernard-Soulier Syndrome

  2018cites this paper
• Assessment of Platelet Aggregation, and Fibrinolytic Activity in Egyptian Patients with Decompensated Liver Cirrhosis

  2018cites this paper
• Do Antiplatelet Drugs Increase the Risk of Bleeding After Dental Implant Surgery? A Case-and-Crossover Study.

  2018cites this paper
• Platelets and Hemostasis

  2018cites this paper
• Reduced platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis

  2018cites this paper
• Angiomatoid Fibrous Histiocytoma With Paraneoplastic Platelet Storage Pool Deficiency

  2018cites this paper
• Abnormal Uterine Bleeding in Adolescent Women

  2018cites this paper
• Inherited Platelet Defects

  2018cites this paper
• Evaluation of Coagulation in the Neurosurgery Patient.

  2018cites this paper