Ribavirin efficiently suppresses porcine nidovirus replication

Highlights ► Ribavirin effectively inhibited porcine nidovirus infection in a dose-dependent manner. ► Ribavirin affected post-entry steps of the replication cycle of PRRSV and PEDV. ► GTP depletion may be essential for the ribavirin activity against porcine nidoviruses. ► Ribavirin did not trigger catastrophic mutations in the nidoviral genome. ► Treatment of ribavirin could be a good antiviral therapy against porcine nidoviruses.

• Publication year

  2012

• Venue

  Virus Research

• Publication date

  2012-10-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.virusres.2012.10.018PMID 23108045PMCID 7114464
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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