Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Neurochemistry

• Publication date

  2008-08-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/j.1471-4159.2008.05488.xPMID 18489716
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes.

  2008cited by this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

  2008cited by this paper
• Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis.

  2007cited by this paper
• Oxidative stress‐induced phosphorylation, degradation and aggregation of α‐synuclein are linked to upregulated CK2 and cathepsin D

  2007cited by this paper
• Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells.

  2007cited by this paper
• Mechanisms involved in the formation of dopamine‐induced intracellular bodies within striatal neurons

  2007cited by this paper
• Autophagosome formation: core machinery and adaptations

  2007cited by this paper
• Induction of Autophagy Promotes Fusion of Multivesicular Bodies with Autophagic Vacuoles in K562 Cells

  2007cited by this paper
• How to Interpret LC3 Immunoblotting

  2007cited by this paper
• Identification of the Substrate Binding Region of Vesicular Monoamine Transporter-2 (VMAT-2) Using Iodoaminoflisopolol as a Novel Photoprobe

  2007cited by this paper
• Cell death in the nervous system

  2006cited by this paper
• Rapamycin pre-treatment protects against apoptosis.

  2006cited by this paper
• Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

  2006cited by this paper
• The roles of intracellular protein-degradation pathways in neurodegeneration

  2006cited by this paper
• Autophagy in neurodegenerative disease: friend, foe or turncoat?

  2006cited by this paper
• Microtubules Facilitate Autophagosome Formation and Fusion of Autophagosomes with Endosomes

  2006cited by this paper
• High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells.

  2006cited by this paper
• Autophagy‐dependent cell survival and cell death in an autosomal dominant familial neurohypophyseal diabetes insipidus in vitro model

  2005cited by this paper
• Autophagy and signaling: their role in cell survival and cell death

  2005cited by this paper
• Autophagy and Its Possible Roles in Nervous System Diseases, Damage and Repair

  2005cited by this paper
• Autophagy in cell death: an innocent convict?

  2005cited by this paper
• Autophagy: molecular machinery for self-eating

  2005cited by this paper
• Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

  2005cited by this paper
• Maturation of Autophagic Vacuoles in Mammalian Cells

  2005cited by this paper
• Reversible Inhibition of α-Synuclein Fibrillization by Dopaminochrome-mediated Conformational Alterations*

  2005cited by this paper
• Another way to die: autophagic programmed cell death

  2005cited by this paper
• Ubiquitin-immunoreactive structures in the midbrain of methamphetamine abusers.

  2005cited by this paper
• Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene

  2005cited by this paper
• The Dynamics of Autophagy Visualised in Live Cells: from Autophagosome Formation to Fusion with Endo/lysosomes

  2005cited by this paper
• Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

  2004cited by this paper
• Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

  2004cited by this paper
• Autophagy: in sickness and in health.

  2004cited by this paper
• Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.

  2004cited by this paper
• α-Synuclein Is Degraded by Both Autophagy and the Proteasome*

  2003cited by this paper
• On the Dynamics of

  2003cited by this paper
• The role of alpha-synuclein in Parkinson's disease: insights from animal models.

  2003cited by this paper
• The role of α-synuclein in Parkinson's disease: insights from animal models

  2003cited by this paper
• Methamphetamine produces neuronal inclusions in the nigrostriatal system and in PC12 cells

  2003cited by this paper
• Induction of Autophagy Causes Dramatic Changes in the Subcellular Distribution of GFP‐Rab24

  2002cited by this paper
• Recent advances in the genetics and pathogenesis of Parkinson disease

  2002cited by this paper
• Methamphetamine-Induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis

  2002cited by this paper
• Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation.

  2001cited by this paper
• The autophagosomal–lysosomal compartment in programmed cell death

  2001cited by this paper
• Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

  2001cited by this paper
• Expression of A53T Mutant But Not Wild-Type α-Synuclein in PC12 Cells Induces Alterations of the Ubiquitin-Dependent Degradation System, Loss of Dopamine Release, and Autophagic Cell Death

  2001cited by this paper
• Beclin–phosphatidylinositol 3‐kinase complex functions at the trans‐Golgi network

  2001cited by this paper
• LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

  2000influential reference
• Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy.

  2000cited by this paper
• Induction of autophagy and inhibition of tumorigenesis by beclin 1

  1999cited by this paper
• The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes.

  1997cited by this paper
• Striatal dopamine nerve terminal markers in human, chronic methamphetamine users

  1996cited by this paper
• Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): Evidence from using CuZn‐superoxide dismutase transgenic mice

  1995cited by this paper
• Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress

  1994cited by this paper
• Autophagic vacuoles rapidly fuse with pre-existing lysosomes in cultured hepatocytes.

  1992cited by this paper
• Prelysosomal and lysosomal connections between autophagy and endocytosis.

  1992cited by this paper
• In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome

  1990cited by this paper
• 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes.

  1982cited by this paper
• Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain.

  1982cited by this paper
• Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine.

  1980cited by this paper

• Retinoic Acid Promotes Neuronal Differentiation While Increasing Proteins and Organelles Related to Autophagy

  2025cites this paper
• Differentially Expressed Nedd4-binding Protein Ndfip1 Protects Neurons Against Methamphetamine-induced Neurotoxicity

  2025cites this paper
• Methamphetamine Increases Tubulo-Vesicular Areas While Dissipating Proteins from Vesicles Involved in Cell Clearance

  2024cites this paper
• Methamphetamine and the brain: Emerging molecular targets and signaling pathways involved in neurotoxicity

  2024cites this paper
• In situ stoichiometry amounts of p62 and poly-ubiquitin exceed the increase of alpha-synuclein during degeneration of catecholamine cells induced by autophagy inhibition in vitro

  2024cites this paper
• Neuroprotective role of chloroquine via modulation of autophagy and neuroinflammation in MPTP-induced Parkinson’s disease

  2023cites this paper
• Lithium engages autophagy for neuroprotection and neuroplasticity: translational evidence for therapy.

  2023cites this paper
• Alterations of Mitochondrial Structure in Methamphetamine Toxicity

  2022cites this paper
• Molecular mechanisms of programmed cell death in methamphetamine-induced neuronal damage

  2022cites this paper
• Lactoferrin Protects against Methamphetamine Toxicity by Modulating Autophagy and Mitochondrial Status

  2021influential citation
• Methamphetamine-induced dopaminergic neurotoxicity as a model of Parkinson’s disease

  2021cites this paper
• Inhibition of Autophagy In Vivo Extends Methamphetamine Toxicity to Mesencephalic Cell Bodies

  2021influential citation
• Neuroprotective Effects of Curcumin in Methamphetamine-Induced Toxicity

  2021influential citation
• Morphology, clearing efficacy, and mTOR dependency of the organelle autophagoproteasome

  2021cites this paper
• Autophagy as a gateway for the effects of methamphetamine: From neurotransmitter release and synaptic plasticity to psychiatric and neurodegenerative disorders.

  2021influential citation
• Neurotoxicity of methamphetamine: Main effects and mechanisms.

  2021cites this paper
• Norepinephrine Protects against Methamphetamine Toxicity through β2-Adrenergic Receptors Promoting LC3 Compartmentalization

  2021cites this paper
• Alpha-Synuclein Toxicity: An Insight on Controversial Issues

  2021cites this paper
• MPTP Neurotoxicity: Actions, Mechanisms, and Animal Modeling of Parkinson’s Disease

  2021cites this paper
• MPTP-induced mouse model of Parkinson’s disease: A promising direction for therapeutic strategies

  2020cites this paper
• Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.

  2020cites this paper
• Differential gene expression and stereological analyses of the cerebellum following methamphetamine exposure

  2020cites this paper
• Promiscuous Roles of Autophagy and Proteasome in Neurodegenerative Proteinopathies

  2020influential citation
• Differential effects of N‐TiO2 nanoparticle and its photo‐activated form on autophagy and necroptosis in human melanoma A375 cells

  2020cites this paper
• Compulsive methamphetamine taking induces autophagic and apoptotic markers in the rat dorsal striatum

  2020cites this paper
• LC3 and ATG5 Overexpression and Neuronal Cell Death in the Prefrontal Cortex of Postmortem Chronic Methamphetamine Users.

  2020cites this paper
• Merging the Multi-Target Effects of Phytochemicals in Neurodegeneration: From Oxidative Stress to Protein Aggregation and Inflammation

  2020cites this paper
• Methamphetamine induces neurotoxicity-associated pathways and stereological changes in prefrontal cortex.

  2019cites this paper
• Cell Clearing Systems Bridging Neuro-Immunity and Synaptic Plasticity

  2019cites this paper
• Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism

  2019cites this paper
• The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability

  2019cites this paper
• Involvement of Mitochondrial Dysfunction on the Toxic Effects Caused by Drugs of Abuse and Addiction

  2018cites this paper
• mTOR Modulates Methamphetamine-Induced Toxicity through Cell Clearing Systems

  2018cites this paper
• Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway

  2018cites this paper
• The Neuroprotective Effects of Cinnamic Aldehyde in an MPTP Mouse Model of Parkinson’s Disease

  2018cites this paper
• Methamphetamine exposure triggers apoptosis and autophagy in neuronal cells by activating the C/EBPβ‐related signaling pathway

  2018cites this paper
• mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders

  2018influential citation
• Interdependency Between Autophagy and Synaptic Vesicle Trafficking: Implications for Dopamine Release

  2018cites this paper
• Epigenetic Effects Induced by Methamphetamine and Methamphetamine-Dependent Oxidative Stress

  2018cites this paper
• Ambiguous Effects of Autophagy Activation Following Hypoperfusion/Ischemia

  2018cites this paper
• Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors

  2017cites this paper
• Role of Autophagy in HIV Pathogenesis and Drug Abuse

  2017cites this paper
• Molecular, Behavioral, and Physiological Consequences of Methamphetamine Neurotoxicity: Implications for Treatment

  2017cites this paper
• A Focus on the Beneficial Effects of Alpha Synuclein and a Re-Appraisal of Synucleinopathies

  2017cites this paper
• Methamphetamine increases Prion Protein and induces dopamine-dependent expression of protease resistant PrPsc.

  2017cites this paper
• Axonal Transport, Parkin, And Α-Synuclein; Novel Therapeutic Targets To Treat Methamphetamine Neurotoxicity

  2017cites this paper
• Resveratrol protects neuronal‐like cells expressing mutant Huntingtin from dopamine toxicity by rescuing ATG4‐mediated autophagosome formation

  2017cites this paper
• Uncovering the hepatotoxic and neurotoxic potential of ß-keto amphetamine (cathinone) derivates: in vitro mechanistic studies.

  2017cites this paper
• Role of Mitochondria in Methamphetamine-Induced Dopaminergic Neurotoxicity: Involvement in Oxidative Stress, Neuroinflammation, and Pro-apoptosis—A Review

  2017cites this paper
• Escalating Methamphetamine Regimen Induces Compensatory Mechanisms, Mitochondrial Biogenesis, and GDNF Expression, in Substantia Nigra

  2017cites this paper
• Nupr1 Modulates Methamphetamine-Induced Dopaminergic Neuronal Apoptosis and Autophagy through CHOP-Trib3-Mediated Endoplasmic Reticulum Stress Signaling Pathway

  2017cites this paper
• Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

  2017cites this paper
• Methamphetamine potentiates HIV-1 gp120-mediated autophagy via Beclin-1 and Atg5/7 as a pro-survival response in astrocytes

  2016cites this paper
• HIV‐1, Drug Addiction, and Autophagy

  2016cites this paper
• The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders

  2016cites this paper
• Protein misfolding and aggregation: Mechanism, factors and detection

  2016cites this paper
• Effects of DDIT4 in Methamphetamine-Induced Autophagy and Apoptosis in Dopaminergic Neurons

  2016cites this paper
• The Autophagoproteasome a Novel Cell Clearing Organelle in Baseline and Stimulated Conditions

  2016cites this paper
• Dopamine exacerbates mutant Huntingtin toxicity via oxidative-mediated inhibition of autophagy in SH-SY5Y neuroblastoma cells: Beneficial effects of anti-oxidant therapeutics.

  2016cites this paper
• Autophagy in acute brain injury

  2016cites this paper
• Proteasome inhibition attenuates rasfonin-induced autophagy concurring with the upregulation of caspase-dependent apoptosis

  2016cites this paper
• Potential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and Methamphetamine.

  2016cites this paper
• HIV‐1, Drug Addiction, and Autophagy HIV ‐ 1, Drug Addiction, and Autophagy

  2016cites this paper
• Epothilone D prevents binge methamphetamine‐mediated loss of striatal dopaminergic markers

  2016cites this paper
• Neuroleptička svojstva urapidila u uvjetima in vitro i in vivo

  2016cites this paper
• Methamphetamine-induced toxicity: The role of autophagy?

  2016influential citation
• Sirtuins and Proteolytic Systems: Implications for Pathogenesis of Synucleinopathies

  2015cites this paper
• Autophagy Inhibition by Caffeine Increases Toxicity of Methamphetamine in SH-SY5Y Neuroblastoma Cell Line

  2015cites this paper
• Rab GTPases

  2015cites this paper
• Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection

  2015cites this paper
• The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations

  2015cites this paper
• Recent Advances in Methamphetamine Neurotoxicity Mechanisms and Its Molecular Pathophysiology

  2015cites this paper
• The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders

  2015cites this paper
• Mitochondria: key players in the neurotoxic effects of amphetamines

  2015cites this paper
• Quantitative bead-based flow cytometry for assaying Rab7 GTPase interaction with the Rab-interacting lysosomal protein (RILP) effector protein.

  2015cites this paper
• Genetics and Molecular Biology of Parkinson Disease

  2015cites this paper
• Cell to cell spreading of misfolded proteins as a therapeutic target in motor neuron disease.

  2014cites this paper
• Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor

  2014influential citation
• MPTP Neurotoxicity: Actions, Mechanisms, and Animal Modelling of Parkinson’s Disease

  2014cites this paper
• DJ-1 AND ATP13A2: TWO PROTEINS INVOLVED IN PARKINSON’S DISEASE

  2014cites this paper
• Chapter 18 Neuronal Autophagy and Prion Proteins

  2013cites this paper
• Re-defining Parkinson's disease.

  2013cites this paper
• Neuronal autophagy and prion proteins

  2013cites this paper
• How Parkinsonian Toxins Dysregulate the Autophagy Machinery

  2013cites this paper
• Existing and emerging mitochondrial-targeting therapies for altering Parkinson's disease severity and progression.

  2013cites this paper
• Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases

  2013cites this paper
• Neurobiology and neuroanatomy of psychiatric symptoms in parkinsonism.

  2013cites this paper
• Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in dopaminergic neuronal cells.

  2012cites this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  2012cites this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy

  2012cites this paper
• Mitochondria and Parkinson's Disease

  2012cites this paper
• A “non-classical” and reliable method for transmission immunoelectronmicroscopy.

  2012cites this paper
• A subcellular analysis of genetic modulation of PINK1 on mitochondrial alterations, autophagy and cell death.

  2012cites this paper
• Defective Autophagy in Parkinson’s Disease: Role of Oxidative Stress

  2012cites this paper
• Altered expression of autophagic genes in the peripheral leukocytes of patients with sporadic Parkinson's disease.

  2011cites this paper
• Diversity in the Regulation of Autophagy and Mitophagy: Lessons from Parkinson's Disease

  2011cites this paper
• Spinal cord and parkinsonism: neuromorphological evidences in humans and experimental studies.

  2011cites this paper
• Transmission of prions within the gut and towards the central nervous system

  2011cites this paper
• Protein clearing pathways in ALS.

  2011cites this paper
• Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation.

  2011cites this paper