Analysis of the mitochondrial proteome in multiple sclerosis cortex.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Biochimica et Biophysica Acta

• Publication date

  2011-05-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.bbadis.2011.01.012PMID 21295140PMCID PMC3074931
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mouse models for multiple sclerosis: historical facts and future implications.

  2011cited by this paper
• Mitochondrial Dysfunction in Parkinson's Disease

  2011cited by this paper
• Radical changes in multiple sclerosis pathogenesis.

  2011cited by this paper
• Mitochondrial Dysfunction in Parkinson's Disease

  2010cited by this paper
• Mitochondria and the Link Between Neuroinflammation and Neurodegeneration

  2010cited by this paper
• Mitochondrial dysfunction in Parkinson's disease.

  2010cited by this paper
• Chemometrics.

  2010cited by this paper
• Neurons express hemoglobin α‐ and β‐chains in rat and human brains

  2009cited by this paper
• Evidence for aerobic ATP synthesis in isolated myelin vesicles.

  2009cited by this paper
• Mitochondria, calcium and cell death: a deadly triad in neurodegeneration.

  2009cited by this paper
• The pathological spectrum of CNS inflammatory demyelinating diseases

  2009cited by this paper
• Magnetic resonance techniques to quantify tissue damage, tissue repair, and functional cortical reorganization in multiple sclerosis.

  2009cited by this paper
• Proteomics/peptidomics tools to find CSF biomarkers for neurodegenerative diseases.

  2009cited by this paper
• Enhanced number and activity of mitochondria in multiple sclerosis lesions

  2009cited by this paper
• Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells

  2009cited by this paper
• Human myelin proteome and comparative analysis with mouse myelin

  2009cited by this paper
• Role of nuclear-encoded subunit Vb in the assembly and stability of cytochrome c oxidase complex: implications in mitochondrial dysfunction and ROS production.

  2009cited by this paper
• Is multiple sclerosis a mitochondrial disease?

  2009cited by this paper
• Quantitative proteomic analysis of the cerebrospinal fluid of patients with multiple sclerosis

  2009cited by this paper
• Mitochondrial proteomics on human fibroblasts for identification of metabolic imbalance and cellular stress

  2009cited by this paper
• Impaired regulation of electron transport chain subunit genes by nuclear respiratory factor 2 in multiple sclerosis.

  2009influential reference
• Gray matter atrophy correlates with MS disability progression measured with MSFC but not EDSS.

  2009cited by this paper
• Clinical proteomics in neurodegenerative disorders

  2008cited by this paper
• Mitochondrial defects in acute multiple sclerosis lesions

  2008cited by this paper
• Expression and regulation of matrix metalloproteinase-12 in experimental autoimmune encephalomyelitis and by bone marrow derived macrophages in vitro.

  2008cited by this paper
• Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

  2008cited by this paper
• Corpora amylacea from multiple sclerosis brain tissue consists of aggregated neuronal cells.

  2008influential reference
• Mitochondrial Medicine for Aging and Neurodegenerative Diseases

  2008cited by this paper
• Gray matter atrophy in multiple sclerosis: A longitudinal study

  2008cited by this paper
• Differential cerebro spinal fluid proteome investigation of Leber hereditary optic neuropathy (LHON) and multiple sclerosis.

  2008cited by this paper
• CSF proteome analysis in multiple sclerosis patients by two‐dimensional electrophoresis

  2008influential reference
• Systems biology approaches for the study of multiple sclerosis

  2008influential reference
• Alzheimer disease and the role of free radicals in the pathogenesis of the disease.

  2008cited by this paper
• Functions and effects of creatine in the central nervous system.

  2008cited by this paper
• The involvement of mitochondria in the pathogenesis of multiple sclerosis.

  2007cited by this paper
• Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

  2007cited by this paper
• A distinctive molecular signature of multiple sclerosis derived from MALDI-TOF/MS and serum proteomic pattern analysis

  2007influential reference
• Discordant white matter N-acetylasparate and diffusion MRI measures suggest that chronic metabolic dysfunction contributes to axonal pathology in multiple sclerosis

  2007cited by this paper
• Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

  2006influential reference
• Assembly of mitochondrial cytochrome c-oxidase, a complicated and highly regulated cellular process.

  2006cited by this paper
• Lumbar cerebrospinal fluid proteome in multiple sclerosis: characterization by ultrafiltration, liquid chromatography, and mass spectrometry.

  2006cited by this paper
• Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

  2006cited by this paper
• Grey matter pathology in multiple sclerosis

  2006cited by this paper
• Axonal conduction and injury in multiple sclerosis: the role of sodium channels

  2006cited by this paper
• Mitochondrial Protein Nitration Primes Neurodegeneration in Experimental Autoimmune Encephalomyelitis*

  2006cited by this paper
• Protein Oxidation and Lipid Peroxidation in Brain of Subjects with Alzheimer's Disease: Insights into Mechanism of Neurodegeneration from Redox Proteomics

  2006cited by this paper
• Grey Matter Pathology in Multiple Sclerosis

  2005cited by this paper
• BMC Medical Genetics BioMed Central Research article Gene expression profiles in Finnish twins with multiple sclerosis

  2005cited by this paper
• Improving feature detection and analysis of surface‐enhanced laser desorption/ionization‐time of flight mass spectra

  2005cited by this paper
• Multi‐slice echo‐planar spectroscopic MR imaging provides both global and local metabolite measures in multiple sclerosis

  2005cited by this paper
• Reactions of peroxynitrite with globin proteins and their possible physiological role.

  2005cited by this paper
• Profiling of myelin proteins by 2D-gel electrophoresis and multidimensional liquid chromatography coupled to MALDI TOF-TOF mass spectrometry.

  2005cited by this paper
• Blue silver: A very sensitive colloidal Coomassie G‐250 staining for proteome analysis

  2004cited by this paper
• Evidence of Nitrosative Damage in the Brain White Matter of Patients with Multiple Sclerosis

  2004cited by this paper
• Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis

  2004cited by this paper
• New antigenic candidates in multiple sclerosis: Identification by serological proteome analysis

  2004cited by this paper
• Proteomic mapping provides powerful insights into functional myelin biology.

  2004cited by this paper
• Nitric oxide and cytochrome oxidase: reaction mechanisms from the enzyme to the cell.

  2003cited by this paper
• Protein Detection in Gels Using Fixation

  2002cited by this paper
• Mitochondrial Abnormalities in Alzheimer's Disease

  2001cited by this paper
• Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions.

  2001cited by this paper
• Neurological disability correlates with spinal cord axonal loss and reduced N‐acetyl aspartate in chronic multiple sclerosis patients

  2000cited by this paper
• Chronic systemic pesticide exposure reproduces features of Parkinson's disease

  2000cited by this paper
• Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis.

  2000cited by this paper
• Axonal transection in the lesions of multiple sclerosis.

  1998cited by this paper
• In‐Gel Digestion of Proteins for MALDI‐MS Fingerprint Mapping

  1998cited by this paper
• AXONAL TRANSECTION IN THE LESIONS OF MULTIPLE SCLEROSIS

  1998cited by this paper
• Cluster analysis and display of genome-wide expression patterns.

  1998cited by this paper
• Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

  1997cited by this paper
• Inhibition of mitochondrial electron transport by peroxynitrite.

  1994cited by this paper
• Microglia, an in vivo source of reactive oxygen species in the brain.

  1993cited by this paper
• The double-edged role of nitric oxide in brain function and superoxide-mediated injury.

  1991cited by this paper
• Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in parkinson's disease

  1991cited by this paper
• Structure and assembly of cytochrome c oxidase.

  1990cited by this paper
• Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease.

  1989cited by this paper
• Mitochondrial Complex I Deficiency in Parkinson's Disease

  1989cited by this paper
• Abnormalities of the electron transport chain in idiopathic parkinson's disease

  1989cited by this paper
• Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis.

  1983cited by this paper
• Distribution of Schwann cell cytoplasm and plasmalemmal vesicles (caveolae) in peripheral myelin sheaths. An electron microscopic study with thin sections and freeze-fracturing

  1977cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Hemoglobin alpha regulates T-lymphocyte activation and mitochondrial function

  2026cites this paper
• Non-canonical hemoglobin: An updated review on its ubiquitous expression

  2025cites this paper
• Epigenetic and Mitochondrial Metabolic Dysfunction in Multiple Sclerosis: A Review of Herbal Drug Approaches and Current Clinical Trials

  2025cites this paper
• Hemoglobin alpha regulates T-lymphocyte activation and mitochondrial function

  2025cites this paper
• Genomic ncRNAs regulating mitochondrial function in neurodegeneration: a neglected clue in the complex etiopathogenesis of multiple sclerosis

  2025cites this paper
• Fueling neurodegeneration: metabolic insights into microglia functions

  2024cites this paper
• The neuropathobiology of multiple sclerosis

  2024cites this paper
• Anti-inflammatory, antioxidant and anti-mitophagy effects of trans sodium crocetinate on experimental autoimmune encephalomyelitis in BALB/C57 mice

  2024cites this paper
• A role for vessel‐associated extracellular matrix proteins in multiple sclerosis pathology

  2024cites this paper
• Heart proteomic profiling discovers MYH6 and COX5B as biomarkers for sudden unexplained death.

  2024cites this paper
• Reactive nitrogen species as therapeutic targets for autophagy/mitophagy modulation to relieve neurodegeneration in multiple sclerosis: Potential application for drug discovery.

  2023cites this paper
• Alterations in Lymphocytic Metabolism—An Emerging Hallmark of MS Pathophysiology?

  2023cites this paper
• Isolated Mitochondrial Preparations and In organello Assays: A Powerful and Relevant Ex vivo Tool for Assessment of Brain (Patho)physiology

  2023cites this paper
• Potential biological contributers to the sex difference in multiple sclerosis progression

  2023cites this paper
• Mitochondrial dysfunction and neurological disorders: A narrative review and treatment overview.

  2023cites this paper
• NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis.

  2023cites this paper
• The complexities of investigating mitochondria dynamics in multiple sclerosis and mouse models of MS

  2023cites this paper
• Advances in human brain proteomics analysis of neurodegenerative diseases

  2022influential citation
• Brain proteome‐wide association study linking‐genes in multiple sclerosis pathogenesis

  2022cites this paper
• Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis

  2022cites this paper
• Proteomics in Multiple Sclerosis: The Perspective of the Clinician

  2022cites this paper
• Integrating Lipidomics and Transcriptomics Reveals the Crosstalk Between Oxidative Stress and Neuroinflammation in Central Nervous System Demyelination

  2022cites this paper
• A Systematic Review of Tissue and Single Cell Transcriptome/Proteome Studies of the Brain in Multiple Sclerosis

  2022cites this paper
• Potential of PINK1 and PARKIN Proteins as Biomarkers for Active Multiple Sclerosis: A Japanese Cohort Study

  2021cites this paper
• Proteomics of Multiple Sclerosis: Inherent Issues in Defining the Pathoetiology and Identifying (Early) Biomarkers

  2021influential citation
• Different neuroinflammatory gene expression profiles in highly active and benign multiple sclerosis.

  2021cites this paper
• Growth Hormone and Neuronal Hemoglobin in the Brain—Roles in Neuroprotection and Neurodegenerative Diseases

  2021cites this paper
• Histological and Top-Down Proteomic Analyses of the Visual Pathway in the Cuprizone Demyelination Model

  2021cites this paper
• The role of complex IV activity in the axonal response of mitochondria to demyelination in experimental disease models of multiple sclerosis

  2021cites this paper
• The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters

  2021cites this paper
• Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis

  2020cites this paper
• Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice

  2020cites this paper
• Targeting endoplasmic reticulum stress and autophagy as therapeutic approaches for neurological diseases.

  2020cites this paper
• Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis

  2020cites this paper
• Genomic, proteomic, and systems biology approaches in biomarker discovery for multiple sclerosis.

  2020cites this paper
• What Have Advances in Transcriptomic Technologies Taught us About Human White Matter Pathologies?

  2020cites this paper
• NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis

  2020cites this paper
• Acteoside ameliorates experimental autoimmune encephalomyelitis through inhibiting peroxynitrite-mediated mitophagy activation.

  2019cites this paper
• Mechanisms of pathophysiology of blood vessels in patients with multiple sclerosis treated with ozone therapy: a systematic review

  2019cites this paper
• Nitration of Drp1 provokes mitophagy activation mediating neuronal injury in experimental autoimmune encephalomyelitis.

  2019cites this paper
• A metabolic perspective on CSF-mediated neurodegeneration in multiple sclerosis.

  2019cites this paper
• The Role of Prostaglandin E2 in the Expression of Hemoglobin During Prenatal and Postnatal Brain Development - Potential Connection to Autism Spectrum Disorders

  2019influential citation
• Mitochondrial dysfunction: maternal protein restriction as a trigger of reactive species overproduction and brainstem energy failure in male offspring brainstem

  2019cites this paper
• Axonal and neuronal degeneration in myelin diseases.

  2019cites this paper
• Targeting mitochondria to protect axons in progressive MS.

  2019cites this paper
• Suppression of the Peripheral Immune System Limits the Central Immune Response Following Cuprizone-Feeding: Relevance to Modelling Multiple Sclerosis

  2019cites this paper
• Mitochondrial Dysfunction and Multiple Sclerosis

  2019cites this paper
• Zone : A Preliminary Study

  2018cites this paper
• Mitochondrial dysfunction and axon degeneration in progressive multiple sclerosis

  2018cites this paper
• Erythropoietin Upregulates Brain Hemoglobin Expression and Supports Neuronal Mitochondrial Activity

  2018cites this paper
• Dysregulation of methionine metabolism in multiple sclerosis

  2018cites this paper
• Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases

  2018cites this paper
• Neurodegeneration in Progressive Multiple Sclerosis.

  2018cites this paper
• Involvement of Mitochondria in Neurodegeneration in Multiple Sclerosis

  2018cites this paper
• An Overview on the Role of Oligodendrocytes and Mitochondria in the Progression of Multiple Sclerosis

  2018cites this paper
• Mitochondrial dynamics in demyelinated axons in a cerebellar slice culture system

  2018cites this paper
• Disturbed Glucose Metabolism in Rat Neurons Exposed to Cerebrospinal Fluid Obtained from Multiple Sclerosis Subjects

  2017cites this paper
• Bioenergetic Failure in Rat Oligodendrocyte Progenitor Cells Treated with Cerebrospinal Fluid Derived from Multiple Sclerosis Patients

  2017cites this paper
• Insights in pathogenesis of multiple sclerosis: nitric oxide may induce mitochondrial dysfunction of oligodendrocytes

  2017cites this paper
• Proteomics of mammalian mitochondria in health and malignancy: From protein identification to function.

  2017cites this paper
• Immunological Enrichment of Low-Abundance Proteins for Comparative Proteomics

  2017cites this paper
• Experimental autoimmune encephalomyelitis from a tissue energy perspective

  2017cites this paper
• Metabolic response to glatiramer acetate therapy in multiple sclerosis patients

  2016cites this paper
• Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease

  2016cites this paper
• Protein undernutrition during development and oxidative impairment in the central nervous system (CNS): potential factors in the occurrence of metabolic syndrome and CNS disease.

  2016cites this paper
• Hemoglobins as new players in multiple sclerosis: metabolic and immune aspects

  2016influential citation
• Insulin-like growth factor 1 (IGF-1) therapy: Mitochondrial dysfunction and diseases.

  2016cites this paper
• Multiple sclerosis is prominent in the Gulf states: Review

  2016cites this paper
• Immunoproteomics technologies in the discovery of autoantigens in autoimmune diseases

  2016cites this paper
• Evidence of extensive RNA oxidation in normal appearing cortex of multiple sclerosis brain.

  2016cites this paper
• Neuronal Hemoglobin Expression and Its Relevance to Multiple Sclerosis Neuropathology

  2016influential citation
• Cross-Species Analysis of Gene Expression and Function in Prefrontal Cortex, Hippocampus and Striatum

  2016cites this paper
• Aging-related diseases and autophagy

  2016cites this paper
• Hemoglobins, Hemorphins, and 11p15.5 Chromosomal Region in Cancer Biology and İmmunity with Special Emphasis for Brain Tumors

  2016cites this paper
• Elucidating the Molecular Basis of Multiple Sclerosis and Understanding theDisease Pathophysiology

  2016cites this paper
• The neuronal metabolite NAA regulates histone H3 methylation in oligodendrocytes and myelin lipid composition

  2016cites this paper
• Analysis of Mitochondrial haemoglobin in Parkinson's disease brain

  2016cites this paper
• Proteomic approaches to the study of renal mitochondria.

  2016cites this paper
• Cerebrovascular pattern improved by ozone autohemotherapy: an entropy-based study on multiple sclerosis patients

  2016cites this paper
• MISSED EVOLUTION OF DEMYELINIZING BRAIN LESIONS DURING SUPPLEMENTATION WITH NATURAL COMPOUNDS: A Case Report.

  2016cites this paper
• Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities.

  2016cites this paper
• Role of autophagy in the pathogenesis of multiple sclerosis

  2015cites this paper
• Changes in Methionine Metabolism and Histone H3 Trimethylation Are Linked to Mitochondrial Defects in Multiple Sclerosis

  2015cites this paper
• Gene expression profiling of prion-infected brains: a novel disease signature for neurodegeneration in non-human primates and in humans

  2015cites this paper
• Upregulation and Mitochondrial Sequestration of Hemoglobin Occur in Circulating Leukocytes during Critical Illness, Conferring a Cytoprotective Phenotype

  2015cites this paper
• The central role of mitochondria in axonal degeneration in multiple sclerosis

  2014cites this paper
• Mammalian nerve globins in search of functions

  2014cites this paper
• Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis.

  2014cites this paper
• Ten years of proteomics in multiple sclerosis

  2014cites this paper
• Therapeutic potential of tyrosine kinase 2 in autoimmunity

  2014cites this paper
• Ozone Autohemotherapy Induces Long-Term Cerebral Metabolic Changes in Multiple Sclerosis Patients

  2014cites this paper
• Metabolic support of axons by oligodendrocytes: Implications for multiple sclerosis.

  2014influential citation
• Localization of hemoglobin in MS cortex and its relevance to MS neuropathology

  2014influential citation
• Neurodegenerative and Fatiguing Illnesses, Infections and Mitochondrial Dysfunction: Use of Natural Supplements to Improve Mitochondrial Function.

  2014cites this paper
• Perturbed Glucose Metabolism: Insights into Multiple Sclerosis Pathogenesis

  2014cites this paper
• Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques

  2014cites this paper
• Time and time-frequency analysis of near-infrared signals for the assessment of ozone autohemotherapy long-term effects in multiple sclerosis

  2013cites this paper
• Investigation of cytocrom c oxidase gene subunits expression on the Multiple sclerosis

  2013cites this paper
• Application of 2D BN/SDS-PAGE coupled with mass spectrometry for identification of VDAC-associated protein complexes related to mitochondrial binding sites for type I brain hexokinase.

  2013cites this paper
• Decreased NAA in Gray Matter is Correlated with Decreased Availability of Acetate in White Matter in Postmortem Multiple Sclerosis Cortex

  2013cites this paper