Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  The Lancet

• Publication date

  2002-06-29

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0140-6736(02)09292-9PMID 12103287
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• SF-36 health survey: Manual and interpretation guide

  2003cited by this paper
• Limb salvage in musculoskeletal oncology.

  2003cited by this paper
• Localized Ewing tumor of bone: final results of the cooperative Ewing's Sarcoma Study CESS 86.

  2001cited by this paper
• A comparison of staging systems for localized extremity soft tissue sarcoma

  2000cited by this paper
• The treatment of high-grade soft tissue sarcomas with preoperative thermoradiotherapy.

  1999cited by this paper
• Evaluating functional outcome in patients with lower extremity sarcoma.

  1999cited by this paper
• Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity.

  1998cited by this paper
• Improved survival with preoperative radiotherapy in resectable rectal cancer.

  1997cited by this paper
• Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma.

  1996cited by this paper
• Development of a measure of physical function for patients with bone and soft tissue sarcoma

  1996cited by this paper
• Soft tissue sarcomas: Preoperative versus postoperative radiotherapy

  1996cited by this paper
• Mobilization of tumour cells during biopsy in an infant with Ewing sarcoma

  1996cited by this paper
• Analysis of variables affecting wound healing after musculoskeletal sarcoma resections

  1996cited by this paper
• Oxford textbook of oncology

  1996cited by this paper
• Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)

  1995cited by this paper
• Detection of intraoperative tumor cell dissemination in patients with breast cancer by use of reverse transcription and polymerase chain reaction.

  1995cited by this paper
• Wound‐Healing Complications after Soft‐Tissue Sarcoma Surgery

  1994cited by this paper
• Local control of soft tissue sarcoma of the extremity: the experience of a multidisciplinary sarcoma group with definitive surgery and radiotherapy.

  1994cited by this paper
• Prescribing, recording, and reporting photon beam therapy

  1993cited by this paper
• Preoperative radiation, surgical margins, and local control of extremity sarcomas of soft tissues

  1993cited by this paper
• Wound complication in surgery of soft tissue sarcoma. Analysis of 103 consecutive patients managed without adjuvant therapy.

  1993cited by this paper
• Wound healing after preoperative radiation for sarcoma of soft tissues.

  1993cited by this paper
• Sarcoma therapy: functional outcome and relationship to treatment parameters.

  1992cited by this paper
• Functional outcome in patients treated with surgery and irradiation for soft tissue tumours

  1991cited by this paper
• Preoperative and postoperative irradiation of soft tissue sarcomas: effect of radiation field size.

  1991cited by this paper
• Preoperative, intraoperative, and postoperative radiation in the treatment of primary soft tissue sarcoma

  1985cited by this paper
• The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy.

  1982cited by this paper
• Sarcomas of soft tissues.

  1963cited by this paper
• Sarcomas of the soft tissues

  1961cited by this paper
• Nonparametric Estimation from Incomplete Observations

  1958cited by this paper
• Individual Comparisons by Ranking Methods

  1945cited by this paper

• The Impact of Radiotherapy Timing on Postoperative Outcomes in Chordoma Patients—A TriNetX Study

  2026cites this paper
• The Role of Radiotherapy in the Management of Chest Wall Soft Tissue Sarcomas

  2026cites this paper
• Transiliac Bone Tunnel Route for Lower Limb Vascular Reconstruction

  2026cites this paper
• Outcomes Following Combined Modality Treatment to the Primary Site in Select Patients With Metastatic Soft Tissue Sarcoma.

  2026cites this paper
• Radiotherapy Response Prediction in Myxofibrosarcomas and Undifferentiated Soft Tissue Sarcomas Using DNA Methylation and Copy Number Profiling.

  2026cites this paper
• A Primer for Pediatric Plastic Surgeons on Pediatric Head and Neck Malignancies: Part IV-Common Disease-Specific Management Strategies for Pediatric Head and Neck Tumors.

  2026cites this paper
• Preoperative hypofractionated radiotherapy in soft tissue sarcomas: institutional experience and clinical implications

  2026influential citation
• Functional and Oncological Outcomes in Patients With Surgically Treated Lower Extremity Soft Tissue Sarcoma

  2025cites this paper
• Principles of Surgical Treatment of Soft Tissue Sarcomas

  2025influential citation
• SCOPES: Short Course Of Preoperative Radiotherapy in Head and Neck, Trunk and Extremity Soft Tissue sarcomas; a randomized phase II clinical trial

  2025cites this paper
• Clinician's primer for soft tissue sarcomas: Nuances of histologic subtypes

  2025cites this paper
• Association of Histologic Subtype With Radiation Response and Survival Outcomes in Synovial Sarcoma

  2025cites this paper
• The Impact of Radiation Dose to Bowel on the Risk of Developing Gastrointestinal Toxicities When Treating Abdominopelvic Soft-Tissue Sarcomas With Preoperative Radiation Therapy

  2025cites this paper
• Management of peripheral-vein leiomyosarcomas, recurrence patterns and individualised treatment strategy.

  2025cites this paper
• Pedicled latissimus dorsi flap and internal mammary perforator flaps for coverage of the latero-cervico-thoracic area after soft-tissue sarcoma resection: A case report.

  2025cites this paper
• Diagnosis and Therapy of Soft Tissue Sarcomas: Spanish Group for Research in Sarcomas (GEIS) Guidelines

  2025cites this paper
• A Comparative Study of Sequential Boost Versus Simultaneous Integrated Boost Radiation Therapy in Postoperative Treatment of Extremity and Trunk Wall Soft Tissue Sarcoma.

  2025cites this paper
• Preoperative intensity‐modulated radiation therapy in lower extremity soft tissue sarcomas with and without dose avoidance of uninvolved skin/subcutaneous tissue

  2025cites this paper
• Outcomes of local therapies for recurrent and radiation associated soft tissue sarcomas of the extremities and trunk: is there a role for re-irradiation?

  2025cites this paper
• Refining surveillance in Myxoid liposarcoma: long-term recurrence patterns and functional outcomes after surgery ± radiotherapy in 186 patients.

  2025cites this paper
• Society of Surgical Oncology Medical Student & Trainee Primer for Skin, Soft Tissue, and Endocrine Surgical Oncology

  2025cites this paper
• The effect of intraoperative radiotherapy in musculoskeletal malignancy: A population study from US SEER database

  2025cites this paper
• Short-term morbidity following primary closure, skin grafting and flap reconstruction after surgical resection of extremity soft-tissue sarcomas: Pushing the limits of limb preservation.

  2025cites this paper
• Lower Levels of TAZ Expression Associated with Post-Surgical Wound Healing Complications in Soft Tissue Sarcoma Patients Treated with Preoperative Radiation

  2025cites this paper
• Clinicopathological background of local recurrence in high grade sarcoma of the extremity with preoperative chemotherapy: a supplementary analysis of JCOG0304

  2025cites this paper
• Advances in Radiation Oncology in Soft Tissue Sarcoma

  2025cites this paper
• Five-Day Preoperative Radiation Therapy for Patients With High-Risk Soft Tissue Sarcoma

  2025cites this paper
• Resektion von Weichteilsarkomen am Oberschenkel

  2025cites this paper
• "Current Use and Clinical Applications of Intraoperative Radiotherapy in Soft Tissue Sarcomas: Insights from a National Survey in Spain".

  2025cites this paper
• A rare case of high-grade synovial sarcoma of the hindfoot.

  2025cites this paper
• Local Antibiotic Administration Decreases Surgical Site Infections Following Extremity Sarcoma Surgery

  2025cites this paper
• The Effect of Lurbinectedin as a Monotherapy and in Combination with Ionizing Radiation on Sarcoma Cell Lines

  2025cites this paper
• Current and Future Developments in Radiation Oncology Approach for Rhabdomyosarcoma

  2025cites this paper
• Innovative sarcoma therapy using multifaceted nano-PROTAC-induced EZH2 degradation and immunity enhancement.

  2025cites this paper
• Treatment strategies for extremity sarcoma patients: a population-based analysis on German clinical cancer registry data

  2025cites this paper
• Top advances of the year: Sarcoma

  2025cites this paper
• [Intensity modulated radiation therapy for treatment of soft tissue sarcomas of the extremities: results of the one arm phase 2 IMRiS study].

  2025cites this paper
• Outcomes and prognostic factors in primary intrathoracic soft tissue sarcoma

  2025cites this paper
• Pandemic driven preoperative moderate hypofractionated radiotherapy for soft tissue sarcomas.

  2025cites this paper
• ESMO-ESTRO consensus statements on the safety of combining radiotherapy with immune checkpoint inhibitors, VEGF(R) inhibitors, or multitargeted tyrosine kinase inhibitors.

  2025cites this paper
• Preoperative accelerated hypofractionated radiotherapy (PHYPORT): state of art and potential clinical application

  2025cites this paper
• [Therapeutic strategy for soft tissue tumors and peripheral sarcomas in adults].

  2025cites this paper
• Neoadjuvant radiochemotherapy in patients with high-risk locally advanced cervical cancer—results of a clinical series

  2025cites this paper
• Radiotherapy Combined with Immune Checkpoint Inhibitor on Murine Fibrosarcoma and a Narrative Review of Clinical Studies

  2025cites this paper
• The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers

  2025cites this paper
• The Landmark Series: Neoadjuvant Radiotherapy in Extremity Soft Tissue Sarcoma—The Way to Hypofractionation

  2025cites this paper
• Local Control in Soft Tissue Sarcomas.

  2025cites this paper
• Radiotherapy and surgery: can this combination be further optimized for patients with metastatic spine disease?

  2025cites this paper
• Indocyanine Green as a Marker for Tissue Ischemia in Spinal Tumor Resections and Extended Revisions: A Technical Note

  2025cites this paper
• Eine randomisierte klinische Studie an PatientInnen mit Weichgewebesarkom der Extremitäten. Verglichen wird Strahlentherapie plus Operation mit vs. ohne zusätzlicher Gabe von Pembrolizumab

  2025cites this paper
• Lokalisierte Weichgewebesarkome

  2025cites this paper
• The Impact of Surgical Margin Distance on Local Recurrence and Survival in Patients with Soft Tissue Sarcoma

  2025cites this paper
• Rhabdomyosarcoma Surgical Update

  2025cites this paper
• SEOM-GEIS Spanish clinical guidelines for the management of soft‑tissue sarcomas (2024)

  2025cites this paper
• Imaging of Peripheral Intraneural Tumors: A Comprehensive Review for Radiologists

  2025cites this paper
• Synovial Sarcoma of the Hand: A Case Report and Literature Review on a Significant Challenge in Treatment

  2025cites this paper
• Functional and donor-site morbidity outcomes of muscle-sparing latissimus dorsi flap in sarcoma defects reconstruction: A single-center cohort study.

  2025cites this paper
• The Challenge of Healing Wounds in Radiation-Injured Skin.

  2025cites this paper
• Hypofractionated Preoperative Radiation Therapy for Extremity and Superficial Trunk Soft Tissue Sarcomas: Results of a Prospective, Phase II Trial.

  2025cites this paper
• Predictors of early soft tissue complications following upper extremity soft tissue sarcoma surgery: a contemporary single-center cohort

  2025cites this paper
• Reporting Matters: Severe Adverse Events in Soft Tissue Sarcoma Therapy—A 30-Year Systematic Review of Placebo- and Non-Systemic-Controlled Randomized Trials

  2025cites this paper
• Technical aspects in sarcoma surgery – a surgical survey among surgeons at sarcoma centers in Germany and Switzerland

  2025influential citation
• ASO Practice Guidelines Series: Soft Tissue Sarcoma of the Extremities and Superficial Trunk

  2025cites this paper
• Präoperative Strahlentherapie und Pembrolizumab bei lokalisierten Weichteilsarkomen der Extremitäten: Ergebnisse der multizentrischen, randomisierten SU2C-SARC032-Studie

  2025cites this paper
• Synovial sarcoma: The influence of clinicopathological variables on overall survival in a UK population.

  2025cites this paper
• Matched Cohort Analysis of Ultra-hypofractionated Versus Standard Fractionation Preoperative Radiation Therapy for Soft Tissue Sarcoma.

  2025cites this paper
• Hypofractionated Radiotherapy for Soft Tissue Sarcomas

  2025cites this paper
• Wound Healing Complications after Neoadjuvant Radiotherapy Combined with Targeted Therapies in Soft Tissue Sarcoma Patients.

  2025cites this paper
• Systematic Review of Soft Tissue Sarcomas in Latin America

  2025cites this paper
• Neoadjuvant Immunotherapy for Resectable Dedifferentiated Liposarcoma: A National Cohort Analysis

  2025cites this paper
• From Intensification to Optimization: Balancing Efficacy, Safety, and Costs in High-Risk Localized Soft Tissue Sarcomas

  2025cites this paper
• Long-term outcome and prognostic factors after chest wall resection and reconstruction

  2025cites this paper
• Radiographic and pathologic response of myxoid liposarcoma treated with preoperative radiotherapy

  2025influential citation
• Preoperative Chemoradiation (Modified Eilber Protocol) Versus Preoperative/Postoperative Radiotherapy for Soft Tissue Sarcomas: A Population-Based Analysis

  2025cites this paper
• Balancing the dose: A meta-analysis of preoperative radiotherapy strategies for soft tissue sarcomas.

  2025cites this paper
• Normal tissue outlining guidelines development for soft tissue sarcoma of the extremities

  2025cites this paper
• Extremity and Truncal Soft Tissue Sarcoma: Risk Assessment and Multidisciplinary Management.

  2024cites this paper
• Update on Dosing and Fractionation for Neoadjuvant Radiotherapy for Localized Soft Tissue Sarcoma

  2024cites this paper
• Immunotherapy and Radiotherapy Combinations for Sarcoma.

  2024cites this paper
• Use of Vacuum-Assisted Closure to Reduce the Likelihood of Wound Complications After Limb-Sparing Resection of Pediatric Primary Bone Sarcomas of the Femur.

  2024cites this paper
• A Pilot Study of Pembrolizumab Combined With Stereotactic Ablative Radiotherapy for Patients With Advanced or Metastatic Sarcoma

  2024cites this paper
• Well-differentiated liposarcomas and dedifferentiated liposarcomas: Systemic treatment options for two sibling neoplasms.

  2024cites this paper
• Are We Ready for Life in the Fast Lane? A Critical Review of Preoperative Hypofractionated Radiotherapy for Localized Soft Tissue Sarcoma.

  2024cites this paper
• MULTIDISCIPLINARY MANAGEMENT OF PLEOMORPHIC DERMAL SARCOMA OF THE SCALP: A SINGLE INSTITUTION STUDY

  2024cites this paper
• Assessment of local complications with preoperative versus postoperative radiotherapy in patients with soft tissue sarcoma in extremities: A randomized comparative clinical trial.

  2024cites this paper
• Frontline and Relapsed Rhabdomyosarcoma (FaR-RMS) Clinical Trial: A Report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

  2024cites this paper
• Evaluation of the Prognostic Value of Pretherapeutic Magnetic Resonance Imaging in Predicting Soft Tissue Sarcoma Radiation Response: A Retrospective Study from a Large Institutional Sarcoma Imaging Database

  2024cites this paper
• Efficacy and Safety of Adjuvant Radiotherapy for Soft Tissue Sarcoma: A Two-Institution Retrospective Observational Study

  2024cites this paper
• A Systematic Review of the Orthoplastic Approach in Adult Lower Extremity Soft Tissue Sarcoma Flap Reconstruction

  2024cites this paper
• Surgical Margins in Musculoskeletal Sarcoma

  2024cites this paper
• Unraveling the Myth of Radiation Resistance in Soft Tissue Sarcomas.

  2024cites this paper
• The Impact of Nanomedicine on Soft Tissue Sarcoma Treated by Radiotherapy and/or Hyperthermia: A Review

  2024influential citation
• Radiotherapy versus limb‐sparing surgery alone in low‐grade soft‐tissue sarcoma of the extremity and trunk wall: a systematic review and meta‐analysis

  2024cites this paper
• Neoadjuvant radiotherapy and wound complication: literature review and review of single surgeon series of myxoid liposarcoma treated with neoadjuvant radiotherapy followed by surgery

  2024cites this paper
• Local treatment in initially unresected non‐rhabdomyosarcoma soft‐tissue sarcomas of children and adolescents: A retrospective single‐center experience

  2024cites this paper
• MOF@COF Nanocapsules Enhance Soft Tissue Sarcoma Treatment: Synergistic Effects of Photodynamic Therapy and PARP Inhibition on Tumor Growth Suppression and Immune Response Activation

  2024cites this paper
• Case report: The first account of undifferentiated sarcoma with epithelioid features originating in the pleura

  2024cites this paper
• Refusal of Adjuvant Therapies and Its Impact on Local Control and Survival in Patients with Bone and Soft Tissue Sarcomas of the Extremities and Trunk

  2024cites this paper
• FLASH Radiotherapy: What Can FLASH's Ultra High Dose Rate Offer to the Treatment of Patients With Sarcoma?

  2024cites this paper
• A Narrative Review of the Assessment and Treatment of Physical Impairments Commonly Seen in Sarcoma Cancer Survivors Using a Rehabilitative Approach

  2024cites this paper