Comparison of dexamethasone and ondansetron in the prophylaxis of emesis induced by moderately emetogenic chemotherapy.

No abstract is available for this paper.

• Publication year

  1991

• Venue

  The Lancet

• Publication date

  1991-08-24

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0140-6736(91)90554-3PMID 1678453
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Comparison of the 5-hydroxytryptamine3 (serotonin) antagonist ondansetron (GR 38032F) with high-dose metoclopramide in the control of cisplatin-induced emesis.

  1990cited by this paper
• Efficacy of ondansetron (GR 38032F) and the role of serotonin in cisplatin-induced nausea and vomiting.

  1990cited by this paper
• Dexamethasone can potentiate the anti-emetic action of a 5HT3 receptor antagonist on cyclophosphamide induced vomiting in the ferret.

  1990cited by this paper
• Ondansetron with and without dexamethasone to treat chemotherapy-induced emesis.

  1989cited by this paper
• Incidence and duration of chemotherapy-induced nausea and vomiting in the outpatient oncology population.

  1989cited by this paper
• The role of ondansetron in the treatment of emesis induced by non-cisplatin-containing chemotherapy regimes.

  1989cited by this paper
• Detection of tumours with nuclear magnetic resonance spectroscopy of plasma.

  1989cited by this paper
• GR 38032F (GR-C507/75): a novel compound effective in the prevention of acute cisplatin-induced emesis.

  1989cited by this paper
• Dose-ranging evaluation of the serotonin antagonist GR-C507/75 (GR38032F) when used as an antiemetic in patients receiving anticancer chemotherapy.

  1988cited by this paper
• A log-linear model for binary crossover data

  1988cited by this paper
• A Log‐Linear Model for Binary Cross‐Over Data

  1987cited by this paper
• Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding

  1987cited by this paper
• Comparison of antiemetic efficacy of domperidone, metoclopramide, and dexamethasone in patients receiving outpatient chemotherapy regimens.

  1987cited by this paper
• Prevention of emesis in patients receiving cytotoxic drugs by GR38032F, a selective 5-HT3 receptor antagonist.

  1987cited by this paper
• Antiemetic efficacy of high-dose dexamethasone: randomized, double-blind, crossover study with high-dose metoclopramide in patients receiving cancer chemotherapy.

  1986cited by this paper
• Antiemetic studies: a methodological discussion.

  1986cited by this paper
• Incidence, course, and severity of delayed nausea and vomiting following the administration of high-dose cisplatin.

  1985cited by this paper
• Antiemetic efficacy of dexamethasone. Randomized, double-blind, crossover study with prochlorperazine in patients receiving cancer chemotherapy.

  1984cited by this paper
• Peripheral 5-hydroxytryptamine receptors and their classification.

  1984cited by this paper
• Double-blind crossover study of the antiemetic efficacy of high-dose dexamethasone versus high-dose metoclopramide.

  1984cited by this paper
• On the receiving end--patient perception of the side-effects of cancer chemotherapy.

  1983cited by this paper
• Methylprednisolone as an antiemetic during cancer chemotherapy--a pilot study.

  1980cited by this paper
• Incidence of nausea and vomiting with cytotoxic chemotherapy: a prospective randomised trial of antiemetics.

  1979cited by this paper
• The use of non-parametric methods in the statistical analysis of the two-period change-over design.

  1972cited by this paper

• A study comparing the effectiveness of ondansetron versus ondansetron combined with dexamethasone for preventing postoperative nausea and vomiting in laparoscopic surgeries

  2024cites this paper
• Chemotherapy-induced gastrointestinal toxicity: Pathogenesis and current management.

  2023cites this paper
• Prevenção e tratamento das náuseas e vômitos induzidos pela quimioterapia antineoplásica

  2022cites this paper
• Approach the prevention of chemotherapy-induced nausea and vomiting in older patients with care

  2022cites this paper
• Prevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes

  2021cites this paper
• 20 – Palliative Care and Quality of Life

  2018cites this paper
• Delayed anaphylactic reaction to intravenous infusion of ondansetron report of 3 cases

  2017cites this paper
• Fatal anaphylactic reaction to intravenous infusion of Ondansetron: a report of two cases

  2017cites this paper
• A Comparasion of Perioperative Ramosetron and Ramosetron with Dexamethasone Prophylaxis for the Prevention of Postoperative Nausea and Vomiting Following Laparoscopic Cholecystectomy under General Anaesthesia

  2017cites this paper
• Effect of Intravenous Dexamethasone on Spinal Anaesthesia With Bupivacaine Plus Fentanyl in Patients Undergoing Vaginal Hysterectomy

  2017cites this paper
• Nausee e vomiti postoperatori

  2016cites this paper
• Combination of 5-HT3 Antagonist and Dexamethasone Is Superior to 5-HT3 Antagonist Alone for PONV Prophylaxis After Laparoscopic Surgeries: A Meta-analysis

  2016cites this paper
• Dexamethasone combined with other antiemetics versus single antiemetics for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: An updated systematic review and meta-analysis.

  2016cites this paper
• Nausées et vomissements postopératoires

  2016cites this paper
• Comparative Evaluation of the Influence of Intravenous Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Surgeries

  2015cites this paper
• A Comparative Study of Suppression of Post Operative nausea and vomiting in Elective Cesarean section under Spinal Anaesthesia using Granisetron, Granisetron+Dexamethasone and Granisetron + Dexamethasone+ Glycopyrrolate

  2015cites this paper
• Efficacy of different antiemetics with different mechanism of action on xylazine induced emesis in cats.

  2014cites this paper
• Comparison of efficacy of ondansetron and dexamethasone combination and ondansetron alone in preventing postoperative nausea and vomiting after laparoscopic cholecystectomy.

  2014cites this paper
• Anticipatory nausea in animal models: a review of potential novel therapeutic treatments

  2014influential citation
• DEXAMETHASONE PROPHYLAXIS ON INCIDENCES OF POST-OPERATIVE NAUSEA AND VOMITING (PONV) IN PATIENTS UNDERGOING GYNECOLOGICAL SURGERIES UNDER SPINAL ANESTHESIA

  2014cites this paper
• Postoperative nausea and vomiting in patients undergoing total abdominal hysterectomy under subarachnoid block: a randomized study of dexamethasone prophylaxis.

  2013cites this paper
• Effect of dexamethasone on emesis after morphine administration in animal model

  2013cites this paper
• Palonosetron for the prevention of chemotherapy-induced nausea and vomiting

  2013cites this paper
• Antiemetic Control with Palonosetron in Patients with Gastrointestinal Cancer Receiving a Fluoropyrimidine-Based Regimen in Addition to Either Irinotecan or Oxaliplatin: A Retrospective Study

  2012cites this paper
• Palliative Care and Quality of Life

  2012cites this paper
• Pharmacological Agents Affecting Emesis

  2012cites this paper
• THE EFFECT OF DEXAMETHASONE ON POST TONSILLECTOMY MORBIDITIES IN CHILDREN

  2011cites this paper
• Clinical evaluation of two antiemetic combinations palonosetron dexamethasone versus ondansetron dexamethasone in chemotherapy of head and neck cancer.

  2010cites this paper
• [Chemotherapy induced emesis: pathophysiology and prevention].

  2010cites this paper
• Preparation of a fast dissolving oral thin film containing dexamethasone: a possible application to antiemesis during cancer chemotherapy.

  2009cites this paper
• Symptom Management in Children with Cancer

  2009cites this paper
• Antiemetic prophylaxis against postoperative nausea and vomiting with ondansetron-dexamethasone combination compared to ondansetron or dexamethasone alone for patients undergoing laparoscopic cholecystectomy.

  2009cites this paper
• Management der Chemotherapie-induzierten Emesis: Was ist Standard nach 20 Jahren klinischer Forschung?

  2009cites this paper
• Antiemetics: an update and the MASCC guidelines applied in clinical practice

  2008cites this paper
• Chemotherapy-induced nausea and vomiting.

  2008cites this paper
• Anti-emetic therapy in cancer chemotherapy: current status.

  2007cites this paper
• Prevention of postoperative nausea and vomiting in children following adenotonsillectomy, using tropisetron with or without low-dose dexamethasone

  2007cites this paper
• Chapter 21 – Palliative Care and Quality of Life

  2007cites this paper
• Nausea e vomito postoperatori

  2007cites this paper
• Nausées et vomissements postopératoires

  2007cites this paper
• Valutazione dei costi della profilassi di un episodio di nausea e vomito indotto da chemioterapia: palonosetron versus 5-HT3 inibitori di prima generazione

  2007cites this paper
• Náuseas y vómitos postoperatorios

  2007cites this paper
• Management of Postoperative Nausea and Vomiting in Children

  2007cites this paper
• Effects of Dexamethasone, Metoclopramide or Acepromazine on Emesis in Cats Sedated with Xylazine Hydrochloride

  2006cites this paper
• Drug Class Review on Newer Antiemetics

  2006cites this paper
• Royal College Recommendations to Improve Academic Anesthesia in the United Kingdom : How They Compare with United States Proposals

  2006cites this paper
• Royal College recommendations to improve academic anesthesia in the United kingdom: how they compare with United States proposals.

  2006cites this paper
• Gastrointestinal toxicity of chemotherapeutic agents.

  2006cites this paper
• Integrate Our International Anesthesia Research Potential Anesthesiologist Scientist: Endangered Species

  2006cites this paper
• Anesthesiologist scientist: endangered species.

  2006cites this paper
• Synthesis and characterization of AP5346, a novel polymer-linked diaminocyclohexyl platinum chemotherapeutic agent.

  2006cites this paper
• Daily challenges in oncology practice. What do we need to know about antiemetics?

  2006cites this paper
• Tumor lysis syndrome induced by dexamethasone.

  2006cites this paper
• Prevention of Delayed Chemotherapy-Induced Nausea and Vomiting After Moderately High to Highly Emetogenic Chemotherapy: Comparison of Ondansetron, Prochlorperazine, and Dexamethasone

  2005cites this paper
• Antiemetische Prophylaxe bei der Chemotherapie gastrointestinaler Tumoren

  2005cites this paper
• Inhalation Induction of Anesthesia with 8% Sevoflurane in Pediatric Ambulatory Surgery: Conditions for Nasotracheal Intubation and the Effects of Dexamethasone on Postoperative Nausea and Vomiting

  2005cites this paper
• Ondansetron and Granisetron in Prophylaxis of Nausea and Emesis Inducedby Cisplatin in Dogs

  2005cites this paper
• Efficacy and tolerability of aprepitant for the prevention of chemotherapy‐induced nausea and emesis over multiple cycles of moderately emetogenic chemotherapy

  2005cites this paper
• Chemotherapy-induced emesis: quality of life and economic impact in the context of current practice in Canada.

  2005cites this paper
• Acute emesis: moderately emetogenic chemotherapy

  2005influential citation
• 5-Hydroxytryptamine-receptor antagonists versus prochlorperazine for control of delayed nausea caused by doxorubicin: a URCC CCOP randomised controlled trial.

  2005cites this paper
• Antitumor active trans-platinum compounds.

  2004cites this paper
• Minimum effective dose of dexamethasone after tonsillectomy

  2004cites this paper
• Treatment of chemotherapy-induced emesis in the 1990s: impact of the 5-HT3 receptor antagonists

  2004cites this paper
• An open, randomized study to compare the efficacy and tolerability of tropisetron with that of a metoclopramidecontaining antiemetic cocktail in the prevention of cisplatin-induced emesis

  2004cites this paper
• Delayed emesis following anticancer chemotherapy

  2004influential citation
• Antiemetic effect of dexamethasone on cisplatin-induced early and delayed emesis in the pigeon.

  2004cites this paper
• Perioperative steroids in tonsillectomy using electrocautery and sharp dissection techniques.

  2004cites this paper
• Comparison of ondansetron with ondansetron plus dexamethasone for antiemetic prophylaxis in children undergoing strabismus surgery.

  2004cites this paper
• Risk-benefit of antiemetics in prevention and treatment of chemotherapy-induced nausea and vomiting.

  2004cites this paper
• Betamethasone does not prevent nausea and vomiting induced by ipecacuanha

  2004cites this paper
• Chemotherapy-related nausea and vomiting - past reflections, present practice and future management.

  2004cites this paper
• 5-HT3-receptor antagonists in the control of delayed-onset emesis.

  2003cites this paper
• Update on Antiemetic Strategies

  2003cites this paper
• Current position of 5HT3 antagonists and the additional value of NK1 antagonists; a new class of antiemetics

  2003cites this paper
• Chemotherapy-Induced Delayed Emesis: What is the Role of 5-HT 3 Antagonists?

  2003cites this paper
• Dexamethasone reduces postoperative vomiting and pain after pediatric tonsillectomy

  2003cites this paper
• Combination Antiemetics: What Is the Evidence?

  2003cites this paper
• Current position of 5HT3 antagonists and the additional value of NK1 antagonists; a new class of antiemetics

  2003cites this paper
• Cost-effectiveness of antiemetics use during cancer chemotherapy

  2003cites this paper
• Dexamethasone is as effective as ondansetron for the prevention of postoperative nausea and vomiting following breast surgery

  2003cites this paper
• Antiemetic therapy.

  2002cites this paper
• Management of Postoperative Nausea and Vomiting in Children

  2002cites this paper
• Dexamethasone reduces pain after tonsillectomy in adults.

  2002cites this paper
• Cost-efficacy analysis of ondansetron regimens for control of emesis induced by noncisplatin, moderately emetogenic chemotherapy.

  2002cites this paper
• Low-dose dexamethasone reduces nausea and vomiting after epidural morphine: a comparison of metoclopramide with saline.

  2002cites this paper
• Corticosteroids in advanced cancer.

  2001cites this paper
• The Effect of Dexamethasone on Postoperative Pain and Emesis After Intrathecal Neostigmine

  2001cites this paper
• Ondansetron P lus M etopimazine C ompared W ith Ondansetron P lus M etopimazine P lus P rednisolone a s Antiemetic P rophylaxis i n P atients R eceiving M ultiple Cycles o f M oderately E metogenic C hemotherapy

  2001cites this paper
• Effects of Smoked Cannabis and Oral δ9-Tetrahydrocannabinol on Nausea and Emesis After Cancer Chemotherapy

  2001cites this paper
• Dexamethasone is a cost-effective alternative to ondansetron in preventing PONV after paediatric strabismus repair.

  2001cites this paper
• Prevention of vomiting after strabismus surgery in children: dexamethasone alone versus dexamethasone plus low‐dose ondansetron

  2001cites this paper
• Ondansetron plus metopimazine compared with ondansetron plus metopimazine plus prednisolone as antiemetic prophylaxis in patients receiving multiple cycles of moderately emetogenic chemotherapy.

  2001cites this paper
• Current status of trans-platinum compounds in cancer therapy

  2001cites this paper
• Effects of dexamethasone on emesis in cats sedated with xylazine hydrochloride.

  2001cites this paper
• Corticosteroids in advanced cancer.

  2001cites this paper
• Dexamethasone for the Prevention of Postoperative Nausea and Vomiting: A Quantitative Systematic Review

  2000cites this paper
• Contribution of dexamethasone to control of chemotherapy-induced nausea and vomiting: a meta-analysis of randomized evidence.

  2000cites this paper
• Contribution o f D examethasone t o C ontrol o f Chemotherapy-Ind uced N ausea a nd V omiting: A M eta-Analysis o f R andomized E vidence

  2000cites this paper
• Antiemetic efficacy of combination therapy with granisetron plus prednisolone plus the dopamine D2 antagonist metopimazine during multiple cycles of moderately emetogenic chemotherapy in patients refractory to previous antiemetic therapy

  2000cites this paper