Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

Two cytokines that signal through the common gamma chain receptor, IL-7 and IL-15, are responsible for the differentiation of developing thymocytes into CD8+ cytotoxic lineage T cells in mice.

• Publication year

  2012

• Venue

  Journal of Experimental Medicine

• Publication date

  2012-11-19

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/jem.20121505PMID 23109710PMCID 3501363
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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