The effect of environmental hypercapnia and salinity on the expression of NHE-like isoforms in the gills of a euryhaline fish (Fundulus heteroclitus).

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Experimental Zoology Part A Comparative Experimental Biology

• Publication date

  2005-06-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1002/JEZ.A.175PMID 15880778
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sodium-hydrogen exchange isoform expression in blood cells: implications for studies in diabetes mellitus.

  2009cited by this paper
• Channels, pumps, and exchangers in the gill and kidney of freshwater fishes: their role in ionic and acid-base regulation.

  2003cited by this paper
• Mechanism of acid adaptation of a fish living in a pH 3.5 lake.

  2003influential reference
• Role of glycosylation in the renal electrogenic Na+-HCO3- cotransporter (NBCe1).

  2003cited by this paper
• Molecular cloning of NHE1 from winter flounder RBCs: activation by osmotic shrinkage, cAMP, and calyculin A.

  2003cited by this paper
• Renal expression of novel Na+/H+ exchanger isoform NHE8.

  2003cited by this paper
• Acid-base regulation in fishes: cellular and molecular mechanisms.

  2002cited by this paper
• Immunolocalisation of sodium/proton exchanger-like proteins in the gills of elasmobranchs.

  2002cited by this paper
• Immunological detection of Na(+)/H(+) exchangers in the gills of a hagfish, Myxine glutinosa, an elasmobranch, Raja erinacea, and a teleost, Fundulus heteroclitus.

  2002cited by this paper
• Expression and cell-specific and membrane-specific localization of NHE-3 in the human and guinea pig upper gastrointestinal tract

  2001cited by this paper
• Expression of Na(+) / H(+) exchanger mRNA in the gills of the Atlantic hagfish (Myxine glutinosa) in response to metabolic acidosis.

  2001influential reference
• Cloning and molecular characterisation of the trout (Oncorhynchus mykiss) vacuolar H(+)-ATPase B subunit.

  2000influential reference
• Immunolocalization of ion-transport proteins to branchial epithelium mitochondria-rich cells in the mudskipper (Periophthalmodon schlosseri).

  2000cited by this paper
• Immunolocalisation of NHE3‐like immunoreactivity in the gills of the rainbow trout (Oncorhynchus mykiss) and the blue‐throated wrasse (Pseudolabrus tetrious)

  1999cited by this paper
• Regulation and intracellular localization of the epithelial isoforms of the Na+/H+ exchangers NHE2 and NHE3.

  1999cited by this paper
• A mechanism for branchial acid excretion in marine fish: identification of multiple Na+/H+ antiporter (NHE) isoforms in gills of two seawater teleosts.

  1999influential reference
• Ion and acid-base regulation in the freshwater mummichog (Fundulus heteroclitus): A departure from the standard model for freshwater teleosts

  1999influential reference
• Proline-rich Motifs of the Na+/H+Exchanger 2 Isoform

  1999cited by this paper
• Quantitative contribution of NHE 2 and NHE 3 to rabbit ileal brush-border Na 1 / H 1 exchange

  1998cited by this paper
• Identification of a Mitochondrial Na+/H+Exchanger*

  1998cited by this paper
• Regulation of apical membrane Na+/H+exchangers NHE2 and NHE3 in intestinal epithelial cell line C2/bbe.

  1998cited by this paper
• Quantitative contribution of NHE2 and NHE3 to rabbit ileal brush-border Na+/H+exchange.

  1998cited by this paper
• Regulation of apical membrane Na+/H+ exchangers NHE2 and NHE3 in intestinal epithelial cell line C2/bbe.

  1998cited by this paper
• Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney.

  1997influential reference
• Na+/H+ exchanger subtypes in the renal tubule: function and regulation in physiology and disease.

  1997cited by this paper
• Molecular physiology of vertebrate Na+/H+ exchangers.

  1997cited by this paper
• Tissue distribution of Na+/H+exchanger isoforms NHE2 and NHE4 in rat intestine and kidney.

  1997cited by this paper
• Mechanisms of acid-base excretion across the gills of a marine fish

  1997cited by this paper
• Tissue distribution of Na+/H+ exchanger isoforms NHE2 and NHE4 in rat intestine and kidney.

  1997cited by this paper
• Na+/H+ Exchanger Isoform 2 (NHE2) is Expressed in the Apical Membrane of the Medullary Thick Ascending Limb

  1997cited by this paper
• Characterization of ion and acid‐base transport in the fresh water adapted mummichog (Fundulus heteroclitus)

  1997cited by this paper
• Sapecin B, a novel fly toxin, blocks macroscopic K+ currents in the GH3 rat pituitary cell line.

  1997cited by this paper
• Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice.

  1997influential reference
• Na+/H+ Exchangers of Mammalian Cells*

  1997cited by this paper
• An avian sodium-hydrogen exchanger.

  1997cited by this paper
• Epithelial localization of a reptilian Na+/H+ exchanger homologous to NHE-1.

  1997cited by this paper
• Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 mRNA.

  1997cited by this paper
• Role of NHE3 in Mediating Renal Brush Border Na+-H+ Exchange

  1996cited by this paper
• NHE2 and NHE3 are human and rabbit intestinal brush-border proteins.

  1996cited by this paper
• Transient Expression of Na+/H+ Exchanger Isoform NHE-2 in LLC-PK1 Cells: Inhibition of Endogenous NHE-3 and Regulation by Hypertonicity

  1996cited by this paper
• Glycosylation of the Na+/H+ exchanger isoform NHE-3 is species specific.

  1996cited by this paper
• Localization of mRNA for the proton pump (H+-ATPase) and exchanger in the rainbow trout gill

  1996cited by this paper
• Biosynthesis and cell surface delivery of the NHE1 isoform of Na+/H+ exchanger in A6 cells.

  1996cited by this paper
• Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney.

  1996cited by this paper
• Differential localization of Na+/H+ exchanger isoforms (NHE1 and NHE3) in polarized epithelial cell lines.

  1996cited by this paper
• Differential regulation of Na+/H+ exchange and H+ -ATPase by pH and HCO3− in kidney proximal tubules

  1995cited by this paper
• Immunolocalization of proton pumps (H+-ATPase) in pavement cells of rainbow trout gill

  1995cited by this paper
• Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3.

  1995cited by this paper
• Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1.

  1995cited by this paper
• 9 Proton Pumps in Fish Gills

  1995cited by this paper
• Na+/H+ exchanger isoforms NHE-2 and NHE-1 in inner medullary collecting duct cells. Expression, functional localization, and differential regulation.

  1994cited by this paper
• ACID-BASE REGULATION, BRANCHIAL TRANSFERS AND RENAL OUTPUT IN A MARINE TELEOST FISH (THE LONG-HORNED SCULPIN MYOXOCEPHALUS OCTODECIMSPINOSUS) DURING EXPOSURE TO LOW SALINITIES

  1994cited by this paper
• Regulation of renal proximal tubular Na/H-exchange: a tissue culture approach.

  1994cited by this paper
• IMMUNOLOCALIZATION OF H+-ATPase IN THE GILL EPITHELIA OF RAINBOW TROUT

  1994cited by this paper
• Na+/H+ exchangers, NHE-1 and NHE-3, of rat intestine. Expression and localization.

  1994cited by this paper
• Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger.

  1993cited by this paper
• Chronic regulation of the Na/H antiporter.

  1993cited by this paper
• Structure/function studies of the epithelial isoforms of the mammalian Na+/H+ exchanger gene family

  1993cited by this paper
• H+-ATPase ACTIVITY IN CRUDE HOMOGENATES OF FISH GILL TISSUE: INHIBITOR SENSITIVITY AND ENVIRONMENTAL AND HORMONAL REGULATION

  1993cited by this paper
• NHE3: a Na+/H+ exchanger isoform of renal brush border.

  1993cited by this paper
• Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2).

  1993cited by this paper
• Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3).

  1992influential reference
• Cloning and expression of a cAMP-activated Na+/H+ exchanger: evidence that the cytoplasmic domain mediates hormonal regulation.

  1992cited by this paper
• Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney.

  1992cited by this paper
• cDNA cloning and immunolocalization of a Na(+)-H+ exchanger in LLC-PK1 renal epithelial cells.

  1991cited by this paper
• ACID-BASE REGULATION IN THE ATLANTIC HAGFISH MYXINE GLUTINOSA

  1991influential reference
• Kinetic analysis of electrogenic 2 Na+-1 H+ antiport in crustacean hepatopancreas.

  1989cited by this paper
• Electrogenic sodium-proton exchange in membrane vesicles from crab (Carcinus maenas) gill.

  1989cited by this paper
• Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter.

  1989cited by this paper
• Acid-Base Regulation

  1988cited by this paper
• A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH.

  1984cited by this paper
• H+ excretion in the marine teleost Parophrys vetulus.

  1982influential reference
• Mechanisms of Acid Extrusion by Two Marine Fishes: The Teleost, Opsanus Beta, and the Elasmobranch, Squalus Acanthias

  1982cited by this paper
• Acid-base regulation.

  1966cited by this paper
• Osmotic Regulation in Aquatic Animals

  1965cited by this paper
• THE ABSORPTION AND EXCRETION OF WATER AND SALTS BY MARINE TELEOSTS

  1930cited by this paper

• The development and plasticity of acid excretion mechanisms in early life stage red drum, Sciaenops ocellatus.

  2025cites this paper
• Unveiling Osmoregulation and Immunological Adaptations in Eleutheronema tetradactylum Gills through High-Throughput Single-Cell Transcriptome Sequencing.

  2024cites this paper
• Hypersalinity tolerance of mummichogs (Fundulus heteroclitus): A branchial transcriptomic analysis.

  2024cites this paper
• Gill ionocyte remodeling mediates blood pH regulation in rockfish (Sebastes diploproa) exposed to environmentally relevant hypercapnia

  2024cites this paper
• Are the effects of catch-and-release angling evident in changes to mRNA abundances related to metabolism, acid–base regulation and stress in lake trout (Salvelinus namaycush) gills?

  2023cites this paper
• Genome−wide expression profile analysis of the NHE and NKA gene family in Rachycentron canadum (Linnaeus, 1766) and its response to salinity adaptation

  2023cites this paper
• Expression of Ion Transporters and Na+/K+-ATPase and H+-ATPase Activities in the Gills and Kidney of Silver Catfish (Rhamdia quelen) Exposed to Different pHs

  2022cites this paper
• Mechanisms of Na+ uptake from freshwater habitats in animals

  2022cites this paper
• Molecular targets of prolactin in mummichogs (Fundulus heteroclitus): ion transporters/channels, aquaporins, and claudins.

  2022cites this paper
• Role of the Basolateral Na+/H+ Exchanger-2 (NHE2) in Ionocytes of Seawater- Acclimated Medaka (Oryzias latipes)

  2022cites this paper
• Genome-wide identification of the NHE gene family in Coilia nasus and its response to salinity challenge and ammonia stress

  2022cites this paper
• Rainbow Trout (Oncorhynchus mykiss) Na+/H+ Exchangers tNhe3a and tNhe3b Display Unique Inhibitory Profiles Dissimilar from Mammalian NHE Isoforms

  2021cites this paper
• Rapid blood acid–base regulation by European sea bass (Dicentrarchus labrax) in response to sudden exposure to high environmental CO2

  2021cites this paper
• The early life stages of the orange-spotted grouper, Epinephelus coioides, exhibit robustness to hypercapnia

  2020cites this paper
• Mechanisms of acid-base regulation following respiratory alkalosis in red drum (Sciaenops ocellatus).

  2020cites this paper
• Acid-base physiology and CO2 homeostasis: Regulation and compensation in response to elevated environmental CO2

  2019cites this paper
• The Use of Immunochemistry in the Study of Branchial Ion Transport Mechanisms

  2019cites this paper
• Evidence for a role of arginine vasotocin receptors in the gill during salinity acclimation by a euryhaline teleost fish.

  2019cites this paper
• Molecular characterization, cellular localization, and light-enhanced expression of Beta-Na+/H+ Exchanger-like in the whitish inner mantle of the giant clam, Tridacna squamosa, denote its role in light-enhanced shell formation.

  2019cites this paper
• Na+/H+ exchanger (NHE) in Pacific white shrimp (Litopenaeus vannamei): Molecular cloning, transcriptional response to acidity stress, and physiological roles in pH homeostasis

  2019cites this paper
• Ion uptake pathways in European sea bass Dicentrarchus labrax.

  2019cites this paper
• Functional aspects of the osmorespiratory compromise in fishes

  2019cites this paper
• Physiological mechanism of osmoregulatory adaptation in anguillid eels

  2018cites this paper
• Dynamics of Gene Expression Responses for Ion Transport Proteins and Aquaporins in the Gill of a Euryhaline Pupfish during Freshwater and High-Salinity Acclimation

  2018cites this paper
• Pharmacological evidence that DAPI inhibits NHE2 in Fundulus heteroclitus acclimated to freshwater.

  2018cites this paper
• Light‐dependent expression of a Na+/H+ exchanger 3‐like transporter in the ctenidium of the giant clam, Tridacna squamosa, can be related to increased H+ excretion during light‐enhanced calcification

  2017influential citation
• Carbon dioxide induced plasticity of branchial acid-base pathways in an estuarine teleost

  2017cites this paper
• Physiological implications of ocean acidification for marine fish: emerging patterns and new insights

  2017cites this paper
• Na+/H+ Exchanger 3 Is Expressed in Two Distinct Types of Ionocyte, and Probably Augments Ammonia Excretion in One of Them, in the Gills of the Climbing Perch Exposed to Seawater

  2017cites this paper
• Functional classification of gill ionocytes and spatiotemporal changes in their distribution after transfer from seawater to freshwater in Japanese seabass

  2017cites this paper
• Transcriptional stress responses to environmental and husbandry stressors in aquaculture species

  2016cites this paper
• Branchial Ionoregulatory Mechanisms of Sodium Regulation in Freshwater Salmonids with Conservational Implications for Arctic Grayling (Thymallus arcticus)

  2016cites this paper
• Research in the Early Twenty-First Century: The Year-Round Research Program Comes of Age

  2015cites this paper
• Ocean warming and acidification modulate energy budget and gill ion regulatory mechanisms in Atlantic cod (Gadus morhua)

  2015cites this paper
• Gill membrane remodeling with soft-water acclimation

  2015cites this paper
• Defining the metabolic compensation pathways employed during low-level hypercapnia in red drum (Sciaenops ocellatus)

  2015cites this paper
• Acid–base regulation in the Dungeness crab (Metacarcinus magister)

  2014cites this paper
• Diverse mechanisms for body fluid regulation in teleost fishes.

  2014cites this paper
• Acid–base regulation in the Dungeness crab (Metacarcinus magister)

  2014cites this paper
• Osmoregulation and branchial plasticity after acute freshwater transfer in red drum, Sciaenops ocellatus.

  2014cites this paper
• Yusuke Kumai and Steve F . Perry larval zebrafish , Danio rerio , in acidic water uptake in + Ammonia excretion via Rhcg 1 facilitates Na

  2014cites this paper
• Physiological impacts of elevated carbon dioxide and ocean acidification on fish.

  2014cites this paper
• Functional characterization of renal ammonia transport and acid-base regulation in teleost and elasmobranch fishes

  2014cites this paper
• Measuring titratable alkalinity by single versus double endpoint titration: An evaluation in two cyprinodont species and implications for characterizing net H+ flux in aquatic organisms.

  2013cites this paper
• Differential acid-base regulation in various gills of the green crab Carcinus maenas: Effects of elevated environmental pCO2.

  2013cites this paper
• Branchial ionocyte organization and ion-transport protein expression in juvenile alewives acclimated to freshwater or seawater

  2012cites this paper
• Molecular cloning and gene expression analysis in aquaculture science: a review focusing on respiration and immune responses in European sea bass (Dicentrarchus labrax)

  2012influential citation
• 8 - Osmoregulation in Estuarine and Intertidal Fishes

  2012cites this paper
• Principles and Patterns of Osmoregulation and Euryhalinity in Fishes

  2012cites this paper
• Osmoregulatory Physiology of Pupfish (Cyprinodon spp.) in Freshwater

  2012influential citation
• Mechanisms and regulation of Na(+) uptake by freshwater fish.

  2012cites this paper
• Identification and Localization of H+-ATPase, NHE2 and NHE3 in the gills of the southern Appalachian brook trout, Salvelinus fontinalis

  2012cites this paper
• Diet influences salinity preference of an estuarine fish, the killifish Fundulus heteroclitus

  2012cites this paper
• The effect of environmental salinity on H+ efflux in the euryhaline barramundi (Lates calcarifer)

  2012cites this paper
• Structures and immunolocalization of Na+, K+ -ATPase, Na+ /H+ exchanger 3 and vacuolar-type H+ -ATPase in the gills of blennies (Teleostei: Blenniidae) inhabiting rocky intertidal areas.

  2012cites this paper
• Effect of hypercapnia on intracellular pH regulation in a rainbow trout hepatoma cell line, RTH 149

  2011cites this paper
• Freshwater Fish Gill Ion Transport: August Krogh to morpholinos and microprobes

  2011cites this paper
• Modulation of ion transporter expression in gill mitochondrion-rich cells of eels acclimated to low-Na(+) or-Cl(-) freshwater.

  2011cites this paper
• Intestinal anion exchange in marine teleosts is involved in osmoregulation and contributes to the oceanic inorganic carbon cycle

  2011cites this paper
• Molecular and Immunohistochemical Identification of a Sodium Hydrogen Exchanger-2C (Nhe2C) Paralog in the Gills of Marine Longhorn Sculpin (Myoxocephalus Octodecemspinosus)

  2011influential citation
• Ammonia excretion via Rhcg1 facilitates Na (cid:1) uptake in larval zebrafish, Danio rerio , in acidic water via facilitates

  2011cites this paper
• Morphofunctional modifications in gill mitochondria-rich cells of Mozambique tilapia transferred from freshwater to 70% seawater, detected by dual observations of whole-mount immunocytochemistry and scanning electron microscopy.

  2011cites this paper
• Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water.

  2011cites this paper
• Rh glycoprotein expression is modulated in pufferfish (Takifugu rubripes) during high environmental ammonia exposure

  2010influential citation
• Molecular identification of Na(+)-H(+) exchanger isoforms (NHE2) in the gills of the euryhaline teleost Fundulus heteroclitus.

  2010cites this paper
• Hypercapnia induced shifts in gill energy budgets of Antarctic notothenioids

  2010cites this paper
• Physiological responses associated with aquatic hypercarbia in the CO₂-tolerant white sturgeon, Acipenser transmontanus

  2010cites this paper
• Acute responses of gill mitochondria-rich cells in Mozambique tilapia Oreochromis mossambicus following transfer from normal freshwater to deionized freshwater

  2009cites this paper
• Molecular characterization and expression analysis of Na+/H+ exchanger (NHE)-1 and c-Fos genes in sea bass (Dicentrarchus labrax, L) exposed to acute and chronic hypercapnia

  2009cites this paper
• A new paradigm for ammonia excretion in aquatic animals: role of Rhesus (Rh) glycoproteins

  2009cites this paper
• Patterns of Acid–Base Regulation During Exposure to Hypercarbia in Fishes

  2009cites this paper
• Complete intracellular pH protection during extracellular pH depression is associated with hypercarbia tolerance in white sturgeon, Acipenser transmontanus.

  2009influential citation
• mRNA expression analysis of the physiological responses to ammonia infusion in rainbow trout

  2009cites this paper
• Ancel Keys Teleost fish osmoregulation : what have we learned

  2008cites this paper
• Osmotic and Ionic Regulation in Fishes

  2008cites this paper
• Gene expression and morphological localization of NHE3, NCC and NKCC1a in branchial mitochondria-rich cells of Mozambique tilapia (Oreochromis mossambicus) acclimated to a wide range of salinities.

  2008cites this paper
• Physiological and molecular mechanisms of osmoregulatory plasticity in killifish after seawater transfer

  2008cites this paper
• Acclimation of ion regulatory capacities in gills of marine fish under environmental hypercapnia.

  2008cites this paper
• Teleost fish osmoregulation: what have we learned since August Krogh, Homer Smith, and Ancel Keys.

  2008cites this paper
• The effects of CO2 and external buffering on ammonia excretion and Rhesus glycoprotein mRNA expression in rainbow trout

  2008cites this paper
• Branchial expression and localization of SLC9A2 and SLC9A3 sodium/hydrogen exchangers and their possible role in acid–base regulation in freshwater rainbow trout (Oncorhynchus mykiss)

  2008cites this paper
• Extracellular acid-base regulation during short-term hypercapnia is effective in a shallow-water crab, but ineffective in a deep-sea crab

  2007cites this paper
• Gill membrane remodeling with soft-water acclimation in zebrafish (Danio rerio).

  2007cites this paper
• Seasonal changes in ionoregulatory variables of the glass eel Anguilla anguilla following estuarine entry: comparison with resident elvers

  2007cites this paper
• Effect of chronic elevated carbon dioxide on the expression of acid-base transporters in the neonatal and adult mouse.

  2007cites this paper
• Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics.

  2007cites this paper
• Modulation of branchial ion transport protein expression by salinity in glass eels (Anguilla anguilla L.)

  2007cites this paper
• Characterization of Na+/H+Exchanger-3 (Nhe3) in the Gills of Longhorn Sculpin (Myoxocephalus Octodecemspinosus)

  2007cites this paper
• Acid-base balance and CO2 excretion in fish: unanswered questions and emerging models.

  2006cites this paper
• Appearance of cuboidal cells in relation to salinity in gills of Fundulus heteroclitus, a species exhibiting branchial Na+ but not Cl− uptake in freshwater

  2006cites this paper
• Na+/H+ antiporter, V-H+-ATPase and Na+/K+-ATPase immunolocalization in a marine teleost (Myoxocephalus octodecemspinosus)

  2006influential citation
• Gene expression after freshwater transfer in gills and opercular epithelia of killifish: insight into divergent mechanisms of ion transport

  2005cites this paper
• Intestinal Anion Exchange in Marine Teleosts Is Involved in Osmoregulation and Contributes to the Oceanic Inorganic Carbon Cycle

  year unknowncites this paper
• The Effects of Salinity on Gene Expression of Ion Transporters in Gulf Killifish ( Fundulus grandis ) Embryos

  year unknowncites this paper