SCIENCE@home

iVirus 2.0: Cyberinfrastructure-supported tools and data to power DNA virus ecology

B. Bolduc,Olivier Zablocki,Jiarong Guo,A. Zayed,D. Vik,Paramvir S. Dehal,E. Wood-Charlson,A. Arkin,Nirav C. Merchant,J. Pett‐Ridge,S. Roux,M. Vaughn,M. Sullivan

Published 2021 in ISME Communications

ABSTRACT

Microbes drive myriad ecosystem processes, but under strong influence from viruses. Because studying viruses in complex systems requires different tools than those for microbes, they remain underexplored. To combat this, we previously aggregated double-stranded DNA (dsDNA) virus analysis capabilities and resources into ‘iVirus’ on the CyVerse collaborative cyberinfrastructure. Here we substantially expand iVirus’s functionality and accessibility, to iVirus 2.0, as follows. First, core iVirus apps were integrated into the Department of Energy’s Systems Biology KnowledgeBase (KBase) to provide an additional analytical platform. Second, at CyVerse, 20 software tools (apps) were upgraded or added as new tools and capabilities. Third, nearly 20-fold more sequence reads were aggregated to capture new data and environments. Finally, documentation, as “live” protocols, was updated to maximize user interaction with and contribution to infrastructure development. Together, iVirus 2.0 serves as a uniquely central and accessible analytical platform for studying how viruses, particularly dsDNA viruses, impact diverse microbial ecosystems.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-67 of 67 references · Page 1 of 1

CITED BY

Showing 1-16 of 16 citing papers · Page 1 of 1