Type 2 diabetes mellitus and exercise impairment

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Reviews in Endocrine & Metabolic Disorders

• Publication date

  2013-01-09

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s11154-012-9234-4PMID 23299658PMCID PMC3593997
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Impaired response to exercise intervention in the vasculature in metabolic syndrome

  2013cited by this paper
• Nationwide Study on Trends in Hospital Admissions for Major Cardiovascular Events and Procedures Among People With and Without Diabetes in England, 2004–2009

  2012cited by this paper
• Adverse Metabolic Response to Regular Exercise: Is It a Rare or Common Occurrence?

  2012cited by this paper
• Intermittent exercise with and without hypoxia improves insulin sensitivity in individuals with type 2 diabetes.

  2012cited by this paper
• The joint association of physical activity and glycaemic control in predicting cardiovascular death and all-cause mortality in the US population

  2012cited by this paper
• Muscle Perfusion

  2012cited by this paper
• Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC–InterAct Study

  2012cited by this paper
• Physical Activity and Mortality in Individuals With Diabetes Mellitus: A Prospective Study and Meta-analysis.

  2012cited by this paper
• Association Between Extracellular Matrix Expansion Quantified by Cardiovascular Magnetic Resonance and Short-Term Mortality

  2012cited by this paper
• Can increases in capillarization explain the early adaptations in metabolic regulation in human muscle to short-term training?

  2012cited by this paper
• Seven days of aerobic exercise training improves conduit artery blood flow following glucose ingestion in patients with type 2 diabetes.

  2011cited by this paper
• Postmaximal contraction blood volume responses are blunted in obese and type 2 diabetic subjects in a muscle-specific manner.

  2011cited by this paper
• Trends over 5 Decades in U.S. Occupation-Related Physical Activity and Their Associations with Obesity

  2011cited by this paper
• Value of primordial and primary prevention for cardiovascular disease: a policy statement from the American Heart Association.

  2011cited by this paper
• Bed rest reduces metabolic protein content and abolishes exercise-induced mRNA responses in human skeletal muscle.

  2011cited by this paper
• Cardiac output is not related to the slowed O2 uptake kinetics in type 2 diabetes.

  2011cited by this paper
• Acute hypoxia and exercise improve insulin sensitivity (SI2*) in individuals with type 2 diabetes

  2011cited by this paper
• Lifetime sedentary living accelerates some aspects of secondary aging.

  2011cited by this paper
• Older type 2 diabetic males do not exhibit abnormal pulmonary oxygen uptake and muscle oxygen utilization dynamics during submaximal cycling exercise.

  2011cited by this paper
• Comparisons of leisure-time physical activity and cardiorespiratory fitness as predictors of all-cause mortality in men and women

  2010cited by this paper
• Mortality trends in the general population: the importance of cardiorespiratory fitness

  2010cited by this paper
• All-Cause Mortality Risk Among a National Sample of Individuals With Diabetes

  2010cited by this paper
• Insulin resistance in adolescents with type 1 diabetes and its relationship to cardiovascular function.

  2010cited by this paper
• Obesity impairs skeletal muscle AMPK signaling during exercise: role of AMPKα2 in the regulation of exercise capacity in vivo

  2010cited by this paper
• Exercise capacity and mortality in older men: a 20-year follow-up study.

  2010cited by this paper
• Exercise Capacity and All-Cause Mortality in African American and Caucasian Men With Type 2 Diabetes

  2009cited by this paper
• Continuous, non-invasive measurement of the haemodynamic response to submaximal exercise in patients with diabetes mellitus: evidence of impaired cardiac reserve and peripheral vascular response

  2009cited by this paper
• Cardiac dysfunction during exercise in uncomplicated type 2 diabetes.

  2009cited by this paper
• Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature.

  2009cited by this paper
• Physical activity, cardiorespiratory fitness and the incidence of type 2 diabetes in a prospective study of men

  2009cited by this paper
• Insulin resistance in adolescents with type 2 diabetes is associated with impaired exercise capacity.

  2009cited by this paper
• The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

  2009cited by this paper
• Volume of exercise and fitness nonresponse in sedentary, postmenopausal women.

  2009cited by this paper
• Impaired stroke volume and aerobic capacity in female adolescents with type 1 and type 2 diabetes mellitus

  2008cited by this paper
• Inflammation and exercise (INFLAME): study rationale, design, and methods.

  2008cited by this paper
• Acute Normobaric Hypoxia Stimulates Erythropoietin Release

  2008cited by this paper
• Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle.

  2008cited by this paper
• Transient Hypoxia Stimulates Mitochondrial Biogenesis in Brain Subcortex by a Neuronal Nitric Oxide Synthase-Dependent Mechanism

  2008cited by this paper
• Exercise Capacity and Cardiovascular/Metabolic Characteristics of Overweight and Obese Individuals With Type 2 Diabetes

  2007cited by this paper
• Skeletal Muscle Deoxygenation Following the Onset of Moderate Exercise Suggests Slowed Microvascular Blood Flow Kinetics in Type 2 Diabetes

  2007cited by this paper
• Insulin Resistance, the Metabolic Syndrome, and Complication Risk in Type 1 Diabetes

  2007cited by this paper
• Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients

  2007cited by this paper
• Normalization of diastolic dysfunction in type 2 diabetics after exercise training.

  2007influential reference
• Improvement in coronary vascular dysfunction produced with euglycaemic control in patients with type 2 diabetes

  2006cited by this paper
• Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the Expression of eNOS

  2005cited by this paper
• Determinants of exercise capacity in patients with type 2 diabetes.

  2005cited by this paper
• Differential effects of exercise on aortic mitochondria.

  2005cited by this paper
• Inactivity, Exercise, and Visceral Fat. STRRIDE: A Randomized, Controlled Study of Exercise Intensity and Amount.

  2005cited by this paper
• A potential decline in life expectancy in the United States in the 21st century.

  2005cited by this paper
• Rosiglitazone improves exercise capacity in individuals with type 2 diabetes.

  2005influential reference
• Risk factors for coronary heart disease in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study.

  2004cited by this paper
• Dose Response to Exercise in Women aged 45-75 yr (DREW): design and rationale.

  2004cited by this paper
• Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes.

  2004cited by this paper
• Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide

  2003cited by this paper
• Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus.

  2003cited by this paper
• Novel actions of thiazolidinediones on vascular function and exercise capacity.

  2003cited by this paper
• Insulin resistance-related factors, but not glycemia, predict coronary artery disease in type 1 diabetes: 10-year follow-up data from the Pittsburgh Epidemiology of Diabetes Complications Study.

  2003cited by this paper
• Abnormal Cardiac and Skeletal Muscle Energy Metabolism in Patients With Type 2 Diabetes

  2003cited by this paper
• Exercise capacity and mortality among men referred for exercise testing.

  2002cited by this paper
• Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

  2002cited by this paper
• Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.

  2001cited by this paper
• Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity.

  2001cited by this paper
• Impact of left ventricular diastolic dysfunction on maximal treadmill performance in normotensive subjects with well-controlled type 2 diabetes mellitus.

  2000cited by this paper
• Low Cardiorespiratory Fitness and Physical Inactivity as Predictors of Mortality in Men with Type 2 Diabetes

  2000influential reference
• Can clinical factors estimate insulin resistance in type 1 diabetes?

  2000cited by this paper
• Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men.

  1999influential reference
• Effects of exercise training on oxygen uptake kinetic responses in women with type 2 diabetes.

  1999cited by this paper
• Cardiorespiratory fitness, body composition, and all-cause and cardiovascular disease mortality in men.

  1999cited by this paper
• Abnormal oxygen uptake kinetic responses in women with type II diabetes mellitus.

  1998cited by this paper
• Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men.

  1995cited by this paper
• Effects of non-insulin-dependent diabetes on oxygen consumption during treadmill exercise.

  1995cited by this paper
• The HERITAGE family study. Aims, design, and measurement protocol.

  1995cited by this paper
• Physical Fitness and All-Cause Mortality

  1995cited by this paper
• Effects of non-insulin-dependent diabetes on oxygen consumption during treadmill exercise.

  1995cited by this paper
• Diabetes Control and Complications Trial

  1993cited by this paper
• Hyperglycemic Pseudohypoxia and Diabetic Complications

  1993cited by this paper
• Physical activity and incidence of non-insulin-dependent diabetes mellitus in women.

  1991cited by this paper
• Glucoregulation and hormonal responses to maximal exercise in non-insulin-dependent diabetes.

  1990cited by this paper
• Effect of physical activity on age-related glucose intolerance.

  1990cited by this paper
• Physical fitness and all-cause mortality. A prospective study of healthy men and women.

  1989cited by this paper
• Abnormal glucoregulation during exercise in type II (non-insulin-dependent) diabetes.

  1987cited by this paper
• Natural course of insulin resistance in type I diabetes.

  1986cited by this paper
• Insulin resistance is a prominent feature of patients with pancreatogenic diabetes.

  1986cited by this paper
• Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus.

  1985cited by this paper
• Relationship Between the Plasma Insulin Response to Oral Glucose and Insulin-stimulated Glucose Utilization in Normal Subjects

  1984cited by this paper
• Studies on the mechanism of improved glucose control during regular exercise in Type 2 (non-insulin-dependent) diabetes

  1984cited by this paper
• Insulin Resistance is a Prominent Feature of Insulin-dependent Diabetes

  1982cited by this paper

• PHYSICAL ACTIVITY AND REHABILITATION STRATEGIES IN THE COMPREHENSIVE MANAGEMENT OF TYPE 2 DIABETES

  2025cites this paper
• Exploring the limits of exercise capacity in adults with type II diabetes

  2025cites this paper
• Physiological mechanisms of neuromuscular impairment in diabetes‐related complications: Can physical exercise help prevent it?

  2025cites this paper
• Ketone monoester ingestion improves cardiac function in adults with type 2 diabetes: a double-blind, placebo controlled, randomised, crossover trial.

  2025cites this paper
• Interrelationship Between Cardiopulmonary Exercise Testing Indices and Markers of Subclinical Cardiovascular Dysfunction in Those with Type 2 Diabetes—An Observational Cross-Sectional Analysis

  2025cites this paper
• Exercise MR of Skeletal Muscles, the Heart, and the Brain

  2024cites this paper
• Impacts of a 12-week aerobic, resistance, and combined exercise training on serum FAM19A5, glucose homeostasis, and novel cardiovascular risk factors among adults with obesity

  2024cites this paper
• Impaired muscle oxygenation despite normal pulmonary function in uncomplicated type 2 diabetes.

  2024cites this paper
• Impact of exercise training in combination with dapagliflozin on physical function in adults with type 2 diabetes mellitus: study protocol for the Dapagliflozin, Exercise Training and physicAl function (DETA) randomised controlled trial

  2024cites this paper
• Association between subclinical right ventricular alterations and aerobic exercise capacity in type 2 diabetes

  2024cites this paper
• Effect of Cardiac Rehabilitation on Cardiorespiratory Fitness in Patients With Acute Myocardial Infarction

  2024cites this paper
• The Effectiveness of Clinician-Led Community-Based Group Exercise Interventions on Health Outcomes in Adults with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

  2024cites this paper
• Data‐driven classification of health status of older adults with diabetes: The diabetes and aging study

  2023cites this paper
• THE EFFECT OF SODIUM BUTYRATE AND AEROBIC EXERCISE WITH TREADMILL, ALONE OR IN COMBINATION, ON BODY WEIGHT AND GLYCEMIC PARAMETERS IN DIABETIC RATS WITH HIGH-FAT-STREPTOZOTOCIN DIET

  2023cites this paper
• Links between Exercise Capacity, Exercise Training, and Metabolism.

  2023cites this paper
• Effect of Exercise Training on Some Anti-Inflammatory Adipokines, High Sensitivity C-Reactive Protein, and Clinical Outcomes in Sedentary Adults With Metabolic Syndrome

  2023cites this paper
• Geriatrische Aspekte bei Diabetes mellitus (Update 2023)

  2023cites this paper
• Type 2 Diabetes Related Mitochondrial Defects in Peripheral Mononucleated Blood Cells from Overweight Postmenopausal Women

  2023cites this paper
• Canagliflozin Prevents Hyperglycemia-Associated Muscle Extracellular Matrix Accumulation and Improves the Adaptive Response to Aerobic Exercise

  2022cites this paper
• Cardiac function and exercise capacity in patients with metabolic syndrome: A cross-sectional study

  2022cites this paper
• Physical performance and glycemic control under SGLT-2-inhibitors in patients with type 2 diabetes and established atherosclerotic cardiovascular diseases or high cardiovascular risk (PUSH): Design of a 4-week prospective observational study

  2022cites this paper
• Activity-related dyspnea in older adults participating in the Canadian Longitudinal Study on Aging

  2022cites this paper
• Type 2 Diabetes and Impaired Physical Function: A Growing Problem

  2022cites this paper
• Muscle Microcirculatory Responses to Incremental Exercises Are Correlated with Peak Oxygen Uptake in Individuals With and Without Type 2 Diabetes Mellitus

  2022cites this paper
• Treadmill running increases the calcium sensitivity of myofilaments in diabetic rats.

  2022cites this paper
• Correlates of cardiorespiratory fitness among overweight or obese individuals with type 2 diabetes

  2022cites this paper
• Re-examining the Classification of Older Adults with Diabetes by Comorbidities and Relationship with Frailty, Disability, and 5-year Mortality.

  2021cites this paper
• Prevalence of peripheral arterial disease and associated factors in people with type 2 diabetes

  2021cites this paper
• Can exercise training help redress sexual dimorphism in type II diabetes outcomes?

  2021cites this paper
• The Application of Exercise Training for Diabetic Peripheral Neuropathy

  2021cites this paper
• Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-controlled trial

  2021cites this paper
• Community-Based Exercise and Lifestyle Program Improves Health Outcomes in Older Adults with Type 2 Diabetes

  2021cites this paper
• Microcirculatory Responses to Muscle and Tendon Exercises in Individuals With and Without Type 2 Diabetes Mellitus and the Association Between Microcirculatory and Exercise Performance

  2021cites this paper
• Inflammatory, antioxidant and glycemic status to different mode of high-intensity training in type 2 diabetes mellitus

  2021cites this paper
• Neurovascular Dysregulation During Exercise in Type 2 Diabetes

  2021cites this paper
• Effects of physical activity on cell‐to‐cell communication during type 2 diabetes: A focus on miRNA signaling

  2021cites this paper
• Cardiorespiratory Fitness and Atherosclerotic Cardiovascular Outcomes by Levels of Baseline Predicted Cardiovascular Risk: The Look AHEAD Study.

  2021cites this paper
• Cardiovascular and systemic determinants of exercise capacity in people with type 2 diabetes mellitus

  2021cites this paper
• Skeletal muscle proteins important for work capacity are altered with type 2 diabetes — Effect of 10‐20‐30 training

  2021cites this paper
• Chronic Medical Conditions:

  2021cites this paper
• The cardiovascular determinants of physical function in patients with end-stage kidney disease on haemodialysis

  2020cites this paper
• Advances in Diabetes Treatment - Once-Weekly Insulin.

  2020cites this paper
• Exercise Training in Diabetes: Start Earlier or Exercise Harder.

  2020cites this paper
• Subclinical Inflammation Is Associated With Reductions in Muscle Oxygenation, Exercise Capacity and Quality of Life in Adults With Type 2 Diabetes.

  2020cites this paper
• Cardiorespiratory Fitness as a Correlate of Cardiovascular, Anthropometric, and Physical Risk Factors: Using the Ruffier Test as a Template

  2020cites this paper
• Near-infrared Spectroscopy of Vastus Lateralis Muscle during Incremental Cycling Exercise in patients with Type 2 Diabetes.

  2020cites this paper
• Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction

  2020cites this paper
• Association between the tissue accumulation of advanced glycation end products and exercise capacity in cardiac rehabilitation patients

  2020cites this paper
• SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism

  2020cites this paper
• Metabolomics reveals the impact of type 2 diabetes on local muscle and vascular responses to ischemic stress.

  2020cites this paper
• Device‐measured physical activity and its association with physical function in adults with type 2 diabetes mellitus

  2020cites this paper
• Greater α1-adrenergic mediated vasoconstriction in contracting skeletal muscle of patients with type 2 diabetes.

  2020cites this paper
• Cardiovascular Determinants of Aerobic Exercise Capacity in Adults With Type 2 Diabetes

  2020cites this paper
• SWELL1-LRRC8 complex regulates skeletal muscle cell size, intracellular signalling, adiposity and glucose metabolism

  2020cites this paper
• Sildenafil enhances central hemodynamic responses to exercise, but not VO2peak, in people with diabetes mellitus.

  2019cites this paper
• Pregnancy and post-partum muscle and cerebral oxygenation during intermittent exercise in gestational diabetes: A pilot study.

  2019cites this paper
• Can an Exercise-Based Educational and Motivational Intervention be Durably Effective in Changing Compliance to Physical Activity and Anthropometric Risk in People with Type 2 Diabetes? A Follow-Up Study

  2019cites this paper
• Association between functional capacity and heart rate variability in patients with uncomplicated type 2 diabetes

  2019cites this paper
• Effect of PPARγ agonist on aerobic exercise capacity in relation to body fat distribution in men with type 2 diabetes mellitus and coronary artery disease: a 1-yr randomized study.

  2019cites this paper
• Physical Activity, Cardiorespiratory Fitness, and the Diabetes Spectrum

  2019cites this paper
• Geriatrische Aspekte bei Diabetes mellitus (Update 2019)

  2019cites this paper
• Factors associated with glycemic control in community-dwelling elderly individuals with type 2 diabetes mellitus in Zhejiang, China: a cross-sectional study

  2019cites this paper
• Quantification of Mitochondrial Oxidative Phosphorylation in Metabolic Disease: Application to Type 2 Diabetes

  2019cites this paper
• Exercise in Metabolic Syndrome and Diabetes: A Central Role for Insulin Sensitivity

  2019cites this paper
• Circulatory and ventilatory power in diabetic patients: Secondary analysis of a randomized controlled trial.

  2019cites this paper
• Modalities of Exercise Intervention for Type 2 Diabetes Mellitus: Narrative Review

  2019cites this paper
• Prognostic value of preprocedural 6-min walk test in patients undergoing transcatheter mitral valve repair—insights from the German transcatheter mitral valve interventions registry

  2018cites this paper
• Exercise intolerance in Type 2 diabetes: is there a cardiovascular contribution?

  2018influential citation
• Rosiglitazone lowers resting and blood pressure response to exercise in men with type 2 diabetes: A 1‐year randomized study

  2018cites this paper
• Aiding sleep in type 2 diabetes: therapeutic considerations.

  2018cites this paper
• Effects of a community-based exercise and motivational intervention on physical fitness of subjects with type 2 diabetes

  2018cites this paper
• Neuropeptide Y1 and alpha‐1 adrenergic receptor‐mediated decreases in functional vasodilation in gluteus maximus microvascular networks of prediabetic mice

  2018cites this paper
• Variations in subclinical left ventricular dysfunction, functional capacity, and clinical outcomes in different heart failure aetiologies

  2018cites this paper
• Diagnosis and Significance of Pulmonary Microvascular Disease in Diabetes

  2018cites this paper
• Exercise capacity and clinical outcomes in adults followed in the Cooperative Study of Sickle Cell Disease (CSSCD)

  2018cites this paper
• Exercise, Blood Flow, and the Skeletal Muscle Microcirculation in Diabetes Mellitus

  2018cites this paper
• Adiposity predicts low cardiorespiratory fitness in individuals with metabolic diseases.

  2018cites this paper
• Metabolomics study of regulatory effects of exercise training on db/db type 2 diabetic mice

  2018cites this paper
• Chronic Medical Conditions: Pulmonary Disease, Organ Transplantation, and Diabetes

  2018cites this paper
• Increased insulin‐stimulated glucose uptake in both leg and arm muscles after sprint interval and moderate‐intensity training in subjects with type 2 diabetes or prediabetes

  2018cites this paper
• Reduced endothelial activation after exercise is associated with improved HbA1c in patients with type 2 diabetes and coronary artery disease

  2017cites this paper
• A conceptual framework for predicting and addressing the consequences of disease‐related microvascular dysfunction

  2017cites this paper
• High-intensity aerobic interval training improves aerobic fitness and HbA1c among persons diagnosed with type 2 diabetes

  2017cites this paper
• Dissociation of local and global skeletal muscle oxygen transport metrics in type 2 diabetes.

  2017cites this paper
• Transport Metrics in Type 2 Diabetes Running title : Oxygenation heterogeneity in diabetes

  2017cites this paper
• The effect of exercise training on clinical outcomes in patients with the metabolic syndrome: a systematic review and meta-analysis

  2017cites this paper
• The effect of training intensity, age and diet on aerobic capacity and metabolic risk factors: testing procedures and training interventions

  2017cites this paper
• Characterization of an in vitro exercise model and the effects of a metabolic endotoxemia on skeletal muscle adaptation to electric pulse stimulation

  2017cites this paper
• Baroreflex and neurovascular responses to skeletal muscle mechanoreflex activation in humans: an exercise in integrative physiology.

  2017cites this paper
• Pulmonary oxygen uptake and muscle deoxygenation responses during ramp incremental exercise and moderate- and heavy-intensity exercise subsequent to priming exercise in type 2 diabetes.

  2017influential citation
• Are Vascular Function and Oxygen Uptake Kinetics Related in People with Type 1 Diabetes

  2017cites this paper
• Association between physical activity patterns and anthropometric characteristics of adults: an issue of public health?

  2017cites this paper
• Mitochondrial dysfunction in calf muscles of patients with combined peripheral arterial disease and diabetes type 2.

  2017cites this paper
• Functional, Structural and Molecular Alterations in the Heart and Kidney During Diabetes Mellitus

  2016influential citation
• Impact of a community-based exercise programme on physical fitness in middle-aged and older patients with type 2 diabetes.

  2016cites this paper
• Peripheral Neuropathy: A Single-Group Clinical Trial Safety of Aerobic Exercise in People With Diabetic

  2016cites this paper
• Physical Activity in Adults with Diabetes Following Prosthetic Rehabilitation.

  2016cites this paper
• The endothelial glycocalyx promotes homogenous blood flow distribution within the microvasculature.

  2016cites this paper
• Physical activity of relatively high intensity in mid‐pregnancy predicts lower glucose tolerance levels

  2016cites this paper
• 当院に教育入院をした薬物未治療の2型糖尿病患者のHomeostasis model assessment-insulin resistanceと6分間歩行試験の関連

  2016cites this paper