Roles of Immune Cells and Mechanisms of Immune Responses in Periodontitis.

No abstract is available for this paper.

• Publication year

  2022

• Venue

  The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association

• Publication date

  2022-01-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3290/j.cjdr.b2440547PMID 35029093
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Downloaded from jdr.sagepub.com at PENNSYLVANIA STATE UNIV on February 23, 2013 For personal use only. No other uses without permission. International and American Associations for Dental ResearchCRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE The Junctional

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  1991cited by this paper
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  1989cited by this paper
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