Leukotrienes and other lipoxygenase products in the pathogenesis and therapy of psoriasis and other dermatoses.

No abstract is available for this paper.

• Publication year

  1983

• Venue

  Archives of Dermatology

• Publication date

  1983-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1001/ARCHDERM.1983.01650310003001PMID 6305285
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nutritional and pharmacological factors in eicosanoid biology.

  2009cited by this paper
• Lipoxygenation of arachidonic acid by subcellular preparations from murine keratinocytes.

  1984cited by this paper
• Local Effects of Synthetic Leukotrienes (LTC4, LTD4, and LTB4) in Human Skin

  1983cited by this paper
• Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin.

  1983cited by this paper
• Regulation of T-lymphocyte mitogenesis by the leukocyte product 15-hydroxy-eicosatetraenoic acid (15-HETE).

  1982cited by this paper
• 2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis.

  1982cited by this paper
• Selective inhibition of 5‐lipoxygenase by 5,6‐methanoleukotriene A4, a stable analogue of leukotriene A4

  1982cited by this paper
• Inhibition of leukotriene biosynthesis by acetylenic analogs

  1982cited by this paper
• The effect of systemic prednisolone on arachidonic acid, and prostaglandin E2 and F2 alpha levels in human cutaneous inflammation.

  1982cited by this paper
• Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid.

  1982cited by this paper
• Enrichment of human platelet phospholipids with linoleic acid diminishes thromboxane release.

  1982cited by this paper
• Evening primrose oil, a dietary prostaglandin precursor, diminishes vascular reactivity to renin and angiotensin II in rats.

  1982cited by this paper
• Benoxaprofen: effect on cutaneous lesions in psoriasis.

  1982cited by this paper
• Effects of phorbol esters on basal epidermal cells derived from ear skin of adult guniea pigs.

  1982cited by this paper
• Treatment of nodular prurigo with benoxaprofen

  1982cited by this paper
• Chemotactic leukotrienes in psoriasis.

  1982cited by this paper
• Benoxaprofen*

  1982cited by this paper
• Effect of benoxaprofen on release of slow-reacting substances from human lung tissue in vitro.

  1982cited by this paper
• Effect of 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin 1(1) (U-60,257), an inhibitor of leukotriene synthesis, on human neutrophil function.

  1982cited by this paper
• Multiple effects of a new anti-inflammatory agent, timegadine, on arachidonic acid release and metabolism in neutrophils and platelets.

  1982cited by this paper
• The pharmacology of benoxaprofen with particular to effects on lipoxygenase product formation.

  1982cited by this paper
• The effect of leukotriene C4 and D4 on cutaneous blood flow in humans.

  1982cited by this paper
• Benoxaprofen: effect on cutaneous lesions in psoriasis.

  1982cited by this paper
• Benoxaprofen for nodular acne.

  1982cited by this paper
• Psoriasis and leukotriene B4.

  1982cited by this paper
• Oral evening-primrose-seed oil improves atopic eczema.

  1982cited by this paper
• Inhibition of arachidonic acid oxidation in vitro by vehicle components.

  1982cited by this paper
• The effect of leucotriene C4 and D4 on cutaneous blood flow in humans

  1982cited by this paper
• Prostaglandins and Dermatology

  1982cited by this paper
• Chapter 20. Lipoxygenase and the Related Arachidonic Acid Metabolites

  1982cited by this paper
• 2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis

  1982cited by this paper
• Commentary: Cyclic Adenosine Monophosphate Regulation of Normal and Psoriatic Epidermis

  1982cited by this paper
• The effect of heat due to ir irradiation on human skin prostaglandin concentrations

  1982cited by this paper
• Inhibition of leukotriene biosynthesis by acetylenic analogs.

  1982cited by this paper
• Evidence for inhibition of leukotriene A4 synthesis by 5,8,11,14-eicosatetraynoic acid in guinea pig polymorphonuclear leukocytes.

  1981cited by this paper
• Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases.

  1981cited by this paper
• Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.

  1981cited by this paper
• Prostacyclin, thromboxane and prostaglandin F2 alpha in suction blister fluid of human skin: effect of systemic aspirin and local glucocorticosteroid treatment.

  1981cited by this paper
• Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.

  1981cited by this paper
• EXACERBATION OF PSORIASIS INDUCED BY INDOMETHACIN

  1981cited by this paper
• Prostaglandin E-mediated mitogenic stimulation of mouse epidermis in vivo by divalent cation ionophore A 23187 and by tumor promoter 12-O-tetradecanoylphorbol-13-acetate.

  1981cited by this paper
• Leukotrienes: mediators of allergic reactions and inflammation.

  1981cited by this paper
• Time course changes in levels of arachidonic acid and prostaglandins D2, E2, F2 alpha in human skin following ultraviolet B irradiation.

  1980cited by this paper
• The inhibitory effects of BW 755C on arachidonic acid metabolism in human polymorphonuclear leukocytes

  1980cited by this paper
• Flavonoids and related compounds as inhibition of arachidonic acid peroxidation.

  1980cited by this paper
• Leukotriene C5: a slow reacting substance derived from eicosapentaenoic acid.

  1980cited by this paper
• Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids

  1980cited by this paper
• Early prostaglandin E synthesis is an obligatory event in the induction of cell proliferation in mouse epidermis in vivo by the phorbol ester TPA.

  1980cited by this paper
• Phospholipase A activity in the skin. Modulators of arachidonic acid release from phosphatidylcholine.

  1979cited by this paper
• Arachidonic acid transformations in normal and psoriatic skin.

  1979cited by this paper
• The effect of indomethacin on cell proliferation induced by chemical and mechanical means in mouse epidermis in vivo.

  1979cited by this paper
• Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway.

  1979cited by this paper
• Prostaglandins E2, F2α and arachidonic acid levels in irradiated and unirradiated skin of psoriatic patients receiving PUVA treatment

  1978cited by this paper
• Stimulation of human eosinophil and neutrophil polymorphonuclear leukocyte chemotaxis and random migration by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid.

  1977cited by this paper
• Inhibition of prostaglandin synthesis by lysolecithin.

  1977cited by this paper
• Glucocorticoid in inflammatory proliferative skin disease reduces arachidonic and hydroxyeicosatetraenoic acids.

  1977cited by this paper
• In vivo chemotaxis induced by polyunsaturated fatty acids.

  1977cited by this paper
• Effects of topical prostaglandin E analogue on normal hairless mouse epidermal DNA synthesis.

  1977cited by this paper
• Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

  1975cited by this paper
• Inhibitor(s) of prostaglandin synthesis in psoriatic plaque

  1975cited by this paper
• Prostaglandin and DNA synthesis in human skin: possible relationship to ultraviolet light effects.

  1975cited by this paper
• Lipid Biochemistry: An Introduction

  1971cited by this paper
• Suppression of sebaceous gland activity with eicosa-5:8:11:14-tetraynoic acid.

  1967cited by this paper
• ROLE OF TRAUMA IN ISOMORPHIC RESPONSE IN PSORIASIS.

  1965cited by this paper

• Leukotriene Antagonists in Dermatology

  2021cites this paper
• Omega-3 Versus Omega-6 Polyunsaturated Fatty Acids in the Prevention and Treatment of Inflammatory Skin Diseases

  2020cites this paper
• Fish Oils and Omega-3 Fatty Acids

  2020cites this paper
• Cytochrome P450 1A1 enhances inflammatory responses and impedes phagocytosis of bacteria in macrophages during sepsis

  2020cites this paper
• Investigation of the immunomodulatory, mitigating and cell reinforcement exercises of night primrose oil in adjuvant-actuated joint inflammation in rodents

  2020cites this paper
• The role of the 12(S)-HETE/GPR31/12-HETER axis in cancer and ischemia-reperfusion injury.

  2019cites this paper
• 12-Lipoxygenase is a Critical Mediator of Type II Pneumocyte Senescence, Macrophage Polarization and Pulmonary Fibrosis after Irradiation.

  2019cites this paper
• Maternal plasma n-3 and n-6 polyunsaturated fatty acids during pregnancy and features of fetal health: Fetal growth velocity, birth weight and duration of pregnancy.

  2017cites this paper
• FTIR AND CARBON ANALYSIS AS TOOLS FOR MONITORING CLINICAL RESPONSE TO MUD THERAPY IN PATIENTS SUFFERING FROM SKIN DISORDERS: CORRELATION OF CHEMICAL AND CLINICAL DATA

  2016cites this paper
• Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3.

  2016cites this paper
• Modulation of Cox-1, 5-, 12- and 15-Lox by Popular Herbal Remedies Used in Southern Italy Against Psoriasis and Other Skin Diseases

  2014cites this paper
• Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1

  2014cites this paper
• Increased risk of sexual dysfunction in male patients with psoriasis: a nationwide population-based follow-up study.

  2013cites this paper
• Fish Oils (Omega-3 Fatty Acids, Docosahexaenoic Acid, Eicosapentaenoic Acid, Dietary Fish, and Fish Oils)

  2013cites this paper
• A Review of Drugs that Induce or Exacerbate Psoriasis

  2012cites this paper
• The management of psoriasis through diet

  2012cites this paper
• Emerging concepts in diet and psoriasis : importance of functional foods

  2012cites this paper
• Study of the immunomodulatory and anti-inflammatory effects of evening primrose oil in adjuvant arthritis

  2008cites this paper
• Pharmacotherapy of diseases mediated by 5-lipoxygenase pathway eicosanoids.

  2007cites this paper
• Leukotriene B(4) enhances tumour necrosis factor-alpha-induced CCL27 production in human keratinocytes.

  2007cites this paper
• Leukotriene B4 enhances tumour necrosis factor‐α‐induced CCL27 production in human keratinocytes

  2007cites this paper
• Inhibition of U 937 Eicosanoid and DNA Synthesis by 5 , 8 , 11 , 14-Eicosatetraynoie Acid , an Inhibitor of Arachidonic Acid Metabolism and Its Partial Reversal by Leukotriene C 4

  2006cites this paper
• Psoriasis : diagnostic et étiopathogénie

  2006cites this paper
• 12-6 and 12-3 Essential fatty acids in rheumatoid arthritis and other rheumatic conditions

  2005cites this paper
• Etretinate or cyclosporin-A treatment normalizes the enhanced respiratory burst of polymorphonuclear leukocytes in psoriasis

  2004cites this paper
• Psoriasis Medical Nutrition Therapy as a Potential Complementary Treatment for Psoriasis-Five Case Reports

  2004cites this paper
• Psoriatic skin reveals the in vivo presence of an epidermal IL-1 inhibitor

  2004cites this paper
• Prostaglandin E(2) suppresses CCL27 production through EP2 and EP3 receptors in human keratinocytes.

  2004cites this paper
• Cytochrome p450: a target for drug development for skin diseases.

  2004cites this paper
• Melanin pigmentation in mammalian skin and its hormonal regulation.

  2004cites this paper
• Cytochrome P-450-dependent production of chemotactic arachidonate metabolites from human neutrophils

  2004cites this paper
• Medical nutrition therapy as a potential complementary treatment for psoriasis--five case reports.

  2004cites this paper
• 15-Hydroxyeicosatetraenoic acid (15-HETE) specifically inhibits the LTB4-induced skin response

  2004influential citation
• Immune-modulating effects of polyunsaturated fatty acids : focus on dihomo-G-linolenic acid

  2004cites this paper
• Plasma n-3 and n-6 fatty acid profiles and their correlations to hair coat scores in horses kept under Malaysian conditions

  2004cites this paper
• Psoriasis‐like factitial dermatitis

  2003cites this paper
• Potential Use of Leukotriene Inhibitors in Treatment of Psoriasis

  2003cites this paper
• The modulatory effects of prostaglandin‐E on cytokine production by human peripheral blood mononuclear cells are independent of the prostaglandin subtype

  2002cites this paper
• NSAIDS in Dermatologic Therapy: Review and Preview

  2002cites this paper
• NSAIDs in Dermatologic Therapy: Review and Preview

  2002cites this paper
• New N -pyridinyl(methyl)-indole-2- and 3-(Alkyl)carboxamides and Derivatives Acting as Systemic and Topical Inflammation Inhibitors

  2002cites this paper
• Lipids and Immunity

  2001cites this paper
• Evaluation der okklusiven Effekte von Hydrokolloidfolien bei chronischer stationärer Psoriasis vulgaris

  2001cites this paper
• N-pyridinyl-indole-3-(alkyl)carboxamides and derivatives as potential systemic and topical inflammation inhibitors.

  2001cites this paper
• Evening primrose oil and borage oil in rheumatologic conditions.

  2000influential citation
• Medikamentöse Therapie der Arthritis psoriatica

  2000cites this paper
• Systemic aspects of psoriasis. An integrative model based on intestinal etiology.

  2000cites this paper
• VML 295 (LY‐293111), a novel LTB4 antagonist, is not effective in the prevention of relapse in psoriasis

  2000cites this paper
• Psoriasis and the arachidonic acid cascade.

  1999influential citation
• Dietary supplementation with omega 3 and omega 6 fatty acids reduces induced white blood cell aggregation in healthy volunteers.

  1998cites this paper
• n-6 and n-3 Essential fatty acids in rheumatoid arthritis and other rheumatic conditions

  1998cites this paper
• 6-Amino-2,4-lutidine carboxamides: α-aminoamide derivatives as systemic and topical inflammation inhibitors

  1998cites this paper
• Investigation on a novel and specific leukotriene B4 receptor antagonist in the treatment of stable plaque psoriasis

  1998cites this paper
• Fettsäuren und Epidermis

  1997cites this paper
• Double-blind pilot study on the effects of ketoconazole on intradermal skin test and leukotriene C4 concentration in the skin of atopic dogs.

  1997cites this paper
• The regulation of CD11b integrin levels on human blood leukocytes and leukotriene B4-stimulated skin by a specific leukotriene B4 receptor antagonist (LY293111).

  1997cites this paper
• Recent advances in the treatment of psoriasis.

  1997cites this paper
• Glucosamine for psoriasis?

  1997cites this paper
• [Fatty acids and the epidermis].

  1997cites this paper
• Tacalcitol (1,24(OH)2D3, TV-02) inhibits phorbol ester-induced epidermal proliferation and cutaneous inflammation, and induces epidermal differentiation in mice

  1996cites this paper
• Psoriasis—An Immunological Disease

  1996cites this paper
• Lipid mediators, free fatty acids and psoriasis.

  1995cites this paper
• Eicosapentaenoic acid‐induced changes in membrane fluidity and cell adhesion molecules in cultured human keratinocytes

  1995cites this paper
• Clinical activity of leukotriene inhibitors.

  1995cites this paper
• Exacerbation and induction of psoriasis by angiotensin-converting enzyme inhibitors.

  1995cites this paper
• Topical auranofin ointment for the treatment of plaque psoriasis.

  1995cites this paper
• Effects of dietary γ-linolenic acid-enriched evening primrose seed oil on the 5-lipoxygenase pathway of neutrophil leukocytes in patients with atopic dermatitis

  1995cites this paper
• Signal transduction pathways in epidermal proliferation and cutaneous inflammation.

  1995cites this paper
• 大豆粕乾留タール(Glyteer)の薬理学的研究(第5報)-抗菌作用-

  1995cites this paper
• The effect of dietary omega-3, -6, and -9 fatty acid supplements on serum fatty acid concentrations in renal dialysis patients: Implications for immune response

  1995cites this paper
• Treatment of refractory psoriatic arthritis.

  1995cites this paper
• Dynamics of epidermal growth and keratinization in psoriasis

  1995cites this paper
• Human in vivo phosphorus 31 magnetic resonance spectroscopy of psoriasis. A noninvasive tool to monitor response to treatment and to study pathophysiology of the disease.

  1994cites this paper
• Elevated expression of human nonpancreatic phospholipase A2 in psoriatic tissue

  1994cites this paper
• Eicosanoids and essential fatty acid modulation in chronic disease and the chronic fatigue syndrome.

  1994cites this paper
• Oxidation and keto reduction of 12-hydroxy-5,8,10,14-eicosatetraenoic acids in bovine corneal epithelial microsomes.

  1994cites this paper
• The effect of very long-chain n-3 fatty acids on immune-related skin diseases.

  1993cites this paper
• The effect of combined fish oil and evening primrose oil (Efamol Marine) on the remission phase of psoriasis: A 7-month double-blind randomized placebo-controlled trial

  1993cites this paper
• Influence of inflammatory mediators and cytokines on human melanocyte function.

  1993cites this paper
• Role of eicosanoids in the pathogenesis of atopic dermatitis.

  1993cites this paper
• Diet and dermatology

  1993cites this paper
• ICAM-1 and E-selectin expression in lesional biopsies of psoriasis patients responding to systemic FK 506 therapy.

  1993cites this paper
• A double-blind, randomized, placebo-controlled trial of n-3 fatty acid based lipid infusion in acute, extended guttate psoriasis

  1993cites this paper
• Chronic growth stimulation of human adult melanocytes by inflammatory mediators in vitro: implications for nevus formation and initial steps in melanocyte oncogenesis.

  1993cites this paper
• THE EFFECTS OF LEUKOTRIENES ON GLIOMA CELL PROLIFERATION IN VITRO

  1993cites this paper
• Effect of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis.

  1993cites this paper
• 1α,25‐dihydroxyvitamin D3 modulates Ia antigen expression induced by interferon‐γ and prostaglandin E2 production in Pam 212 cells

  1992cites this paper
• Leukotriene B4-induced human melanocyte pigmentation and leukotriene C4-induced human melanocyte growth are inhibited by different isoquinolinesulfonamides.

  1992cites this paper
• The inter‐relation between inflammation and epidermal proliferation in normal skin following epicutaneous application of leukotriene‐B4—an immunohistochemical study

  1992cites this paper
• Oxidative Injury in Dermatopathology

  1992cites this paper
• Studies and perspectives of signal transduction in the skin

  1992cites this paper
• Percutaneous Absorption and Metabolism of Lonapalene in Psoriatic Skin

  1992cites this paper
• 5-lipoxygenase inhibitors and their anti-inflammatory activities.

  1992cites this paper
• 1 alpha,25-dihydroxyvitamin D3 modulates Ia antigen expression induced by interferon-gamma and prostaglandin E2 production in Pam 212 cells.

  1992cites this paper
• Successful treatment of therapy-resistant acral psoriatic lesions with intravenous administration of Lipo PGE1 (prostaglandin E1 incorporated into lipid microspheres)

  1992cites this paper
• Immunohistochemical Localization of Superoxide Dismutase in Normal Human Skin, Psoriasis Vulgaris and Atopic Dermatitis

  1992cites this paper
• Effects of novel synthesized retinobenzoic acid (Am-80) on adenylate cyclase and arachidonic acid release in pig epidermis.

  1992cites this paper
• Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea.

  1992cites this paper
• Inhibition of leukotriene B4 biosynthesis by disulfiram and A-64077 during carrageenan-induced pleurisy in the rat.

  1991cites this paper
• Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs.

  1991cites this paper