The role of the sympathetic nervous system in obesity-related hypertension

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Current Hypertension Reports

• Publication date

  2009-05-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/S11906-009-0036-3PMID 19442330PMCID PMC2814329
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Obesity and hypertension: two epidemics or one?

  2004influential reference
• Aldosterone Antagonism Attenuates Obesity-Induced Hypertension and Glomerular Hyperfiltration

  2004cited by this paper
• Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity*

  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
• Mechanisms of obesity-associated cardiovascular and renal disease.

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  2001cited by this paper
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  2000cited by this paper
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  1999influential reference
• Lisinopril versus hydrochlorothiazide in obese hypertensive patients: a multicenter placebo-controlled trial. Treatment in Obese Patients With Hypertension (TROPHY) Study Group.

  1997cited by this paper
• Plasma angiotensinogen concentrations in obese patients.

  1997cited by this paper
• Renal denervation attenuates the sodium retention and hypertension associated with obesity.

  1995cited by this paper
• Body mass index and blood pressure in Korean men and women: the Korean National Blood Pressure Survey

  1994cited by this paper
• Resistance to metabolic actions of insulin and its role in hypertension.

  1994cited by this paper
• The Surprising Kidney‐Fluid Mechanism for Pressure Control ‐Its Infinite Gain!

  1990cited by this paper
• Chronic angiotensin II infusion decreases renal norepinephrine overflow in conscious dogs.

  1984cited by this paper

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