Hydrogen exchange measurement of the free energy of structural and allosteric change in hemoglobin.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Science

• Publication date

  1992-06-19

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1126/SCIENCE.256.5064.1684PMID 1609279PMCID PMC3562468
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Primary structure effects on peptide group hydrogen exchange

  1993cited by this paper
• Protein folding studied using hydrogen-exchange labeling and two-dimensional NMR.

  1992cited by this paper
• Molecular code for cooperativity in hemoglobin.

  1992cited by this paper
• Hydrogen-exchange labeling study of the allosteric R-state to T-state equilibrium in methemoglobin

  1991cited by this paper
• Salt, phosphate and the Bohr effect at the hemoglobin beta chain C terminus studied by hydrogen exchange.

  1988cited by this paper
• Allosteric energy at the hemoglobin beta chain C terminus studied by hydrogen exchange.

  1988cited by this paper
• Oxygen binding constants for human hemoglobin tetramers.

  1987cited by this paper
• Allosteric sensitivity in hemoglobin at the alpha-subunit N-terminus studied by hydrogen exchange.

  1986cited by this paper
• Individual breathing reactions measured by functional labeling and hydrogen exchange methods.

  1986cited by this paper
• Two-dimensional 1H NMR studies of cytochrome c: hydrogen exchange in the N-terminal helix.

  1986cited by this paper
• Protein hydrogen exchange studied by the fragment separation method.

  1985cited by this paper
• Exchange behavior of the H-bonded amide protons in the 3 to 13 helix of ribonuclease S.

  1983cited by this paper
• Hydrogen exchange studies of proteins: recent advances in medium and high resolution methods.

  1983cited by this paper
• Identification of an allosterically sensitive unfolding unit in hemoglobin.

  1983cited by this paper
• Amide protein exchange and surface conformation of the basic pancreatic trypsin inhibitor in solution. Studies with two-dimensional nuclear magnetic resonance.

  1982cited by this paper
• Individual breathing reactions measured in hemoglobin by hydrogen exchange methods.

  1980cited by this paper
• The slowest allosterically responsive hydrogens in hemoglobin. Completion of the hydrogen exchange survey.

  1980cited by this paper
• An experimental procedure for increasing the structural resolution of chemical hydrogen-exchange measurements on proteins: application to ribonuclease S peptide.

  1979cited by this paper
• Haemoglobin: the structural changes related to ligand binding and its allosteric mechanism.

  1979cited by this paper
• Thermodynamic studies on the oxygenation and subunit association of human hemoglobin. Temperature dependence of the linkage between dimer-tetramer association and oxygenation state.

  1979cited by this paper
• Thermodynamic studies on subunit assembly in human hemoglobin. Temperature dependence of the dimer-tetramer association constants for oxygenated and unliganded hemoglobins.

  1977cited by this paper
• MEASUREMENT OF STRUCTURAL AND FREE ENERGY CHANGES IN HEMOGLOBIN BY HYDROGEN EXCHANGE METHODS

  1975cited by this paper
• Stereochemistry of cooperative effects in haemoglobin.

  1970cited by this paper
• Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

  1970cited by this paper
• Hydrogen exchange in proteins.

  1966cited by this paper
• Comparison of experimental binding data and theoretical models in proteins containing subunits.

  1966cited by this paper
• LINKED FUNCTIONS AND RECIPROCAL EFFECTS IN HEMOGLOBIN: A SECOND LOOK.

  1964cited by this paper
• Deuterium exchange of poly-DL-alanine in aqueous solution.

  1957cited by this paper

• Cooperative Substructure and Energetics of Allosteric Regulation of the Catalytic Core of the E3 Ubiquitin Ligase Parkin by Phosphorylated Ubiquitin

  2024cites this paper
• How to design a protein that can be switched on and off

  2024cites this paper
• Hydrogen/deuterium exchange for the analysis of carbohydrates.

  2023cites this paper
• HX and Me: Understanding Allostery, Folding, and Protein Machines.

  2022cites this paper
• Hydrogen/Deuterium Exchange and Nuclear Magnetic Resonance Spectroscopy Reveal Dynamic Allostery on Multiple Time Scales in the Serine Protease Thrombin.

  2021cites this paper
• Allostery in Orai1 binding to calmodulin revealed from conformational thermodynamics

  2019cites this paper
• Application of Hydrogen / Deuterium Exchange Mass Spectrometry in Structural Biology and Molecular Medicine

  2017cites this paper
• Role of Terahertz (THz) Fluctuations in the Allosteric Properties of the PDZ Domains

  2017cites this paper
• Measuring hydrogen exchange rates in invisible protein excited states

  2014cites this paper
• Hydrogen-deuterium exchange studies by mass spectrometry: A method for obtaining conformational structures of proteins in solution

  2014cites this paper
• Preparation and characterization of chemically synthesized polyaniline–polystyrene blends as a carbon dioxide gas sensor

  2013cites this paper
• Hot-wire vapor deposited tungsten and molybdenum oxide films used for carrier injection/transport in organic optoelectronic devices

  2013cites this paper
• Radiation damping in modern NMR experiments: progress and challenges.

  2013cites this paper
• Local electronic properties at organic-metal interfaces: thiophene derivatives on Pt(111).

  2012cites this paper
• Measuring rapid hydrogen exchange in the homodimeric 36 kDa HIV‐1 integrase catalytic core domain

  2011cites this paper
• Measuring rapid hydrogen exchange in the homodimeric 36 kDa HIV‐1 integrase catalytic core domain

  2011cites this paper
• Shikimate kinase (EC 2.7.1.71) from Mycobacterium tuberculosis: kinetics and structural dynamics of a potential molecular target for drug development.

  2011cites this paper
• Interface Engineering for Organic Electronics

  2010cites this paper
• Controllable Shifts in Threshold Voltage of Top‐Gate Polymer Field‐Effect Transistors for Applications in Organic Nano Floating Gate Memory

  2010cites this paper
• Room temperature ionic liquids in electrosynthesis and spectroelectrochemical characterization of poly(para-phenylene)

  2010cites this paper
• Field effect transistor fabricated from polyaniline-polyvinyl alcohol nanocomposite

  2010cites this paper
• Local Conformational Stability of HIV-1 gp120 in Unliganded and CD4-Bound States as Defined by Amide Hydrogen/Deuterium Exchange

  2010cites this paper
• On the roles of substrate binding and hinge unfolding in conformational changes of adenylate kinase.

  2010cites this paper
• Energy‐Level Alignment at Organic/Metal and Organic/Organic Interfaces

  2009cites this paper
• Protein Loop Prediction by Fragment Assembly

  2007cites this paper
• New p-type Organic Semiconducting Materials for Organic Transistor

  2006cites this paper
• Cooperative alpha-helix unfolding in a protein-DNA complex from hydrogen-deuterium exchange.

  2006cites this paper
• Cooperative α‐helix unfolding in a protein–DNA complex from hydrogen–deuterium exchange

  2006cites this paper
• Effects of co-operative ligand binding on protein amide NH hydrogen exchange.

  2006cites this paper
• Large Area Electronics Using Printing Methods

  2005cites this paper
• Understanding noncovalent interactions: ligand binding energy and catalytic efficiency from ligand-induced reductions in motion within receptors and enzymes.

  2004cites this paper
• Noncovalent interactions: defining cooperativity. Ligand binding aided by reduced dynamic behavior of receptors. Binding of bacterial cell wall analogues to ristocetin A.

  2004cites this paper
• Ligandeninduzierte Bewegungseinschränkung mit Stärkung nichtkovalenter Wechselwirkungen in Rezeptoren und Enzymen: Quelle für Bindungsenergie und katalytische Wirkung

  2004cites this paper
• Mass Spectrometric Approaches Using Electrospray Ionization Charge States and Hydrogen-Deuterium Exchange for Determining Protein Structures and Their Conformational Changes*

  2004cites this paper
• The stability of the cytochrome c scaffold as revealed by NMR spectroscopy.

  2004cites this paper
• A cooperative model for proton pumping in cytochrome c oxidase.

  2004cites this paper
• Structural model for an alkaline form of ferricytochrome C.

  2003cites this paper
• Protein structure change studied by hydrogen-deuterium exchange, functional labeling, and mass spectrometry

  2003cites this paper
• Hydrogen Exchange-Mass Spectrometry

  2002cites this paper
• Early intermediates in the folding of dihydrofolate reductase from Escherichia coli detected by hydrogen exchange and NMR

  2002cites this paper
• The problem of proton transfer in membranes.

  2002cites this paper
• Hydrogen Exchange-Mass Spectrometry OPTIMIZATION

  2002cites this paper
• Prediction of a 12-residue loop in bovine pancreatic trypsin inhibitor: effects of buried water.

  2001cites this paper
• Backbone Dynamics of Plastocyanin in Both Oxidation States

  2001cites this paper
• Mechanisms and uses of hydrogen exchange S

  2001cites this paper
• Redox-dependent hydration of cytochrome c and cytochrome b(5) studied through (17)O NMRD.

  2001cites this paper
• A signature of the T → R transition in human hemoglobin

  2001cites this paper
• Distal ligand reactivity and quaternary structure studies of proximally detached hemoglobins.

  2001cites this paper
• A further clue to understanding the mobility of mitochondrial yeast cytochrome c: a (15)N T1rho investigation of the oxidized and reduced species.

  2001cites this paper
• Hydrogen-deuterium exchange as a probe of folding and assembly in viral capsids.

  2001cites this paper
• Structural Characterization of Protein Kinase A as a Function of Nucleotide Binding

  2001cites this paper
• Perspectives in inorganic structural biology: solution structures of metalloproteins

  2000cites this paper
• Ligand-induced changes in the structure and dynamics of a human class Mu glutathione S-transferase.

  2000cites this paper
• Fractal ion-channel behavior generates fractal firing patterns in neuronal models.

  1999cites this paper
• Connection between the taxonomic substates and protonation of histidines 64 and 97 in carbonmonoxy myoglobin.

  1999cites this paper
• Denatured states of human carbonic anhydrase II: an NMR study of hydrogen/deuterium exchange at tryptophan‐indole‐HN sites

  1999cites this paper
• Solution structure of reduced horse heart cytochrome c

  1999cites this paper
• Energetic components of the allosteric machinery in hemoglobin measured by hydrogen exchange.

  1998cites this paper
• The solution structure of oxidized rat microsomal cytochrome b5.

  1998cites this paper
• The orientation and dynamics of substance P in lipid environments

  1998cites this paper
• Crystal structure of the S-nitroso form of liganded human hemoglobin.

  1998cites this paper
• Two structural subdomains of barstar detected by rapid mixing NMR measurement of amide hydrogen exchange

  1998cites this paper
• Protein stability function relations: beta-lactoglobulin-A sulphydryl group reactivity and its relationship to protein unfolding stability.

  1998cites this paper
• Hydrogen exchange and protein folding.

  1998cites this paper
• Effect of osmolytes on the exchange rates of backbone amide protons in proteins.

  1998cites this paper
• Reduction in the amide hydrogen exchange rates of an anti-lysozyme Fv fragment due to formation of the Fv-lysozyme complex.

  1997cites this paper
• Human recombinant [C22A] FK506‐binding protein amide hydrogen exchange rates from mass spectrometry match and extend those from NMR

  1997cites this paper
• Solution structure of oxidized Saccharomyces cerevisiae iso-1-cytochrome c.

  1997cites this paper
• Amide hydrogen exchange determined by mass spectrometry: application to rabbit muscle aldolase.

  1996cites this paper
• Global changes in amide hydrogen exchange rates for a protein antigen in complex with three different antibodies.

  1996cites this paper
• Loop problem in proteins: Developments on Monte Carlo simulated annealing approach

  1996cites this paper
• Thermal-induced unfolding domains in aldolase identified by amide hydrogen exchange and mass spectrometry.

  1996cites this paper
• Mechanisms and uses of hydrogen exchange.

  1996cites this paper
• Hydrogen bond stabilities in membrane-reconstituted alamethicin from amide-resolved hydrogen-exchange measurements.

  1996cites this paper
• Adenylate kinase from Sulfolobus acidocaldarius: expression in Escherichia coli and characterization by Fourier transform infrared spectroscopy.

  1996cites this paper
• Using fractals and nonlinear dynamics to determine the physical properties of ion channel proteins.

  1996cites this paper
• Thermally induced hydrogen exchange processes in small proteins as seen by FTIR spectroscopy

  1996cites this paper
• Three extremely thermostable proteins from Sulfolobus and a reappraisal of the 'traffic rules'.

  1996cites this paper
• [15] Thermodynamic parameters from hydrogen exchange measurements

  1995cites this paper
• Local perturbations by ligand binding of hydrogen deuterium exchange kinetics in a four-helix bundle protein, acyl coenzyme A binding protein (ACBP).

  1995cites this paper
• Protein folding intermediates: native-state hydrogen exchange.

  1995cites this paper
• On the pH dependence of amide proton exchange rates in proteins.

  1995cites this paper
• Thermodynamic parameters from hydrogen exchange measurements.

  1995cites this paper
• Noncooperativity of biotin binding to tetrameric streptavidin.

  1995cites this paper
• Early intermediates in the folding of dihydrofolate reductase from escherichia coli detected by hydrogen exchange and NMR

  1995cites this paper
• A statistical mechanical model for hydrogen exchange in globular proteins

  1995cites this paper
• Noncooperativity of biotin binding to tetrameric streptavidin.

  1995cites this paper
• THE THERMALLY INDUCED HYDROGEN EXCHANGE IN DIFFERENT PROTEINS AS SEEN BY FTIR SPECTROSCOPY

  1995cites this paper
• Quantitative endoproteinase GluC footprinting of cooperative Ca2+ binding to calmodulin: proteolytic susceptibility of E31 and E87 indicates interdomain interactions.

  1995cites this paper
• Structure and energy change in hemoglobin by hydrogen exchange labeling.

  1994cites this paper
• Probing high order structure of proteins by fast-atom bombardment mass spectrometry

  1994cites this paper
• Structural dynamics in an electron–transfer complex

  1994cites this paper
• How much is a stabilizing bond worth?

  1994cites this paper
• Protein stability parameters measured by hydrogen exchange

  1994cites this paper
• Hydrogen-deuterium exchange in the free and immunoglobulin G-bound protein G B-domain.

  1994cites this paper
• Proton NMR studies of the structural and dynamical effect of chemical modification of a single aromatic side-chain in a snake cardiotoxin. Relation to the structure of the putative binding site and the cytolytic activity of the toxin.

  1994cites this paper
• The loop problem in proteins: A monte carlo simulated annealing approach

  1993cites this paper
• Single‐site modifications of half‐ligated hemoglobin reveal autonomous dimer cooperativity within a quaternary T tetramer

  1993cites this paper
• Hydrogen exchange in unligated and ligated staphylococcal nuclease.

  1993cites this paper
• Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

  1993cites this paper