The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification

The PP2A subunit Twins and the SV40 small T antigen, a functional mimic of Twins, counteract Plk4 autophosphorylation, leading to its stabilization and to subsequent centriole amplification.

• Publication year

  2011

• Venue

  Journal of Cell Biology

• Publication date

  2011-10-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201107086PMID 21987638PMCID 3198173
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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