Morphogenesis of vascular and neuronal networks and the relationship between their remodeling processes.

Vascular and neuronal networks represent important examples of body structures created by processes of branching morphogenesis. Migration to an appropriate target in both axons and blood vessels are mediated by chemo-repulsive and attractive signals and the proximity of nerves and blood vessels suggest that there may be molecular crosstalk and common cues between nerves and blood vessels. Vascular endothelial growth factor (VEGF), a key angiogenetic factor, also has direct effects on the nervous system in terms of axon outgrowth and survival. Conversely, nerve growth factor (NGF), a well-known neurotropic molecule, also exhibits angiogenic properties. Available data on the morphogenesis of vascular and neuronal networks and on the relationship between their remodeling processes will be the focus of the present study.

• Publication year

  2022

• Venue

  Brain Research Bulletin

• Publication date

  2022-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.brainresbull.2022.05.015PMID 35659566
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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