Ceramic Nanofiber Materials for Wound Healing and Bone Regeneration: A Brief Review

Ceramic nanofibers have been shown to be a new horizon of research in the biomedical area, due to their differentiated morphology, nanoroughness, nanotopography, wettability, bioactivity, and chemical functionalization properties. Therefore, considering the impact caused by the use of these nanofibers, and the fact that there are still limited data available in the literature addressing the ceramic nanofiber application in regenerative medicine, this review article aims to gather the state-of-the-art research concerning these materials, for potential use as a biomaterial for wound healing and bone regeneration, and to analyze their characteristics when considering their application.

• Publication year

  2022

• Venue

  Materials

• Publication date

  2022-05-31

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.3390/ma15113909PMID 35683207PMCID 9182284
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure and biological compatibility of polycaprolactone/zinc-hydroxyapatite electrospun nanofibers for tissue regeneration

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• Recent progress and challenges in solution blow spinning.

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• 3D nanofibrous bioactive glass scaffolds produced by one-step spinning process

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• Cell behavior on silica-hydroxyapatite coaxial composite

  2021influential reference
• Piezoelectric calcium/manganese-doped barium titanate nanofibers with improved osteogenic activity

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• Antifungal activity of TiO2-CeO2 nanofibers against Candida fungi

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• Facile One-Step Deposition of Ag Nanoparticles on SiO2 Electrospun Nanofiber Surfaces for Label-Free SERS Detection and Antibacterial Dressing.

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• Biodegradable Elastic Sponge from Nanofibrous Biphasic Calcium Phosphate Ceramic as an Advanced Material for Regenerative Medicine

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• Silica nanoparticles-incorporated carbon nanofibers as bioactive biomaterial for bone tissue engineering

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• New Perspective of Nano Fibers: Synthesis and Applications

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• Construction of a nanofiber network within 3D printed scaffolds for vascularized bone regeneration.

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• Overview of methods for enhancing bone regeneration in distraction osteogenesis: Potential roles of biometals

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• Bioactive glasses and electrospun composites that release cobalt to stimulate the HIF pathway for wound healing applications

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• A radial 3D polycaprolactone nanofiber scaffold modified by biomineralization and silk fibroin coating promote bone regeneration in vivo.

  2021cited by this paper
• Bone tissue engineering techniques, advances and scaffolds for treatment of bone defects.

  2021cited by this paper
• Evaluation of nano grain growth of TiO2 fibers fabricated via centrifugal jet spinning

  2020cited by this paper
• Electrospinning preparation and microstructure characterization of homogeneous diphasic mullite ceramic nanofibers

  2020cited by this paper
• Osteoconductive and electroactive carbon nanofibers/hydroxyapatite nanocomposite tailored for bone tissue engineering: in vitro and in vivo studies

  2020cited by this paper
• Magnesium-containing silk fibroin/polycaprolactone electrospun nanofibrous scaffolds for accelerating bone regeneration

  2020cited by this paper
• Macroporous scaffolds developed from CaSiO3 nanofibers regulating bone regeneration via controlled calcination.

  2020cited by this paper
• Joint wound healing using polymeric dressing of chitosan/strontium-doped titanium dioxide with high antibacterial activity

  2020cited by this paper
• Antibacterial Efficiency of Zn, Mg and Sr Doped Bioactive Glass for Bone Tissue Engineering.

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• Successful electrospinning fabrication of ZrO2 nanofibers: A detailed physical – chemical characterization study

  2020cited by this paper
• Fabrication of Multifunctional Cellulose/TiO2 /AgComposite Nanofibers Scaffold with Antibacterial and Bioactivity Properties for Future Tissue Engineering Applications.

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• Plasma-induced FeSiAl@Al2O3@SiO2 core–shell structure for exceptional microwave absorption and anti-oxidation at high temperature

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• A comparative study on SiO2 nanofiber production via two novel non-electrospinning methods: Centrifugal spinning vs solution blowing

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• Wound healing and antimicrobial effect of active secondary metabolites in chitosan-based wound dressings: A review.

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• Electrospun nanofibers in wound healing

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• Calcium ion mediated rapid wound healing by nano-ZnO doped calcium phosphate-chitosan-alginate biocomposites

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• Antibacterial Biohybrid Nanofibers for Wound Dressings.

  2020cited by this paper
• Solution blow spinning (SBS) and SBS-spun nanofibers: Materials, methods, and applications

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• Simple and robust fabrication and characterization of conductive carbonized nanofibers loaded with gold nanoparticles for bone tissue engineering applications.

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• Novel 3D Hybrid Nanofiber Scaffolds for Bone Regeneration

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• Prospects of antibacterial bioactive glass nanofibers for wound healing: An in vitro study

  2020influential reference
• Development of titanium dioxide nanowire incorporated poly(vinylidene fluoride–trifluoroethylene) scaffolds for bone tissue engineering applications

  2019cited by this paper
• Enhancing biological activity of bioactive glass scaffolds by inorganic ion delivery for bone tissue engineering

  2019cited by this paper
• Electrospun polymer biomaterials

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• Therapeutic Metallic Ions in Bone Tissue Engineering: A Systematic Review of The Literature

  2019cited by this paper
• 5. Ultrafine Nanofiber Formation by Centrifugal Spinning

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• Electrospinning 3D bioactive glasses for wound healing

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• In situ assembly of well-dispersed Ag nanoparticles on the surface of polylactic acid-Au@polydopamine nanofibers for antimicrobial applications.

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• Formation of core-shell structured calcium silicate fiber via sol-gel electrospinning and controlled calcination

  2019cited by this paper
• Biomaterials for bone tissue engineering scaffolds: a review

  2019influential reference
• Fabrication and Characterizations of Silica Nanoparticle Embedded Carbon Nanofibers

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• Current advances in bone tissue engineering concerning ceramic and bioglass scaffolds: A review

  2019influential reference
• Complex relationship between alumina and selenium-doped carbonated hydroxyapatite as the ceramic additives to electrospun polycaprolactone scaffolds for tissue engineering applications

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• Synthesis and characterization of alumina fibers using solution blow spinning

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• Calcium phosphate submicrometric fibers produced by solution blow spinning

  2019cited by this paper
• Constructing 3D scaffold with 40-nm-diameter hollow mesoporous bioactive glass nanofibers

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• Stretchable and electrically conductive polyurethane- silver/graphene composite fibers prepared by wet-spinning process

  2019cited by this paper
• Bioactive glass nanofibers for tissue engineering

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• Carbon Nanofibers Coated with Silicon/Calcium-Based Compounds for Medical Application

  2019cited by this paper
• Wound dressings: Current advances and future directions

  2019cited by this paper
• Latest Progress in Electrospun Nanofibers for Wound Healing Applications.

  2019cited by this paper
• Zinc-Based Biomaterials for Regeneration and Therapy.

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• Bone grafts: which is the ideal biomaterial?

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• Electrospun Polycaprolactone Fibrous Membranes Containing Ag, TiO2 and Na2Ti6O13 Particles for Potential Use in Bone Regeneration

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• Bioactive calcium phosphate materials and applications in bone regeneration

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• Innovative Biomaterials for Bone Regrowth

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• Electrospun polycaprolactone/hydroxyapatite/ZnO nanofibers as potential biomaterials for bone tissue regeneration

  2019cited by this paper
• Polylactic acid-based porous scaffolds doped with calcium silicate and dicalcium phosphate dihydrate designed for biomedical application.

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• The facile synthesis and bioactivity of a 3D nanofibrous bioglass scaffold using an amino-modified bacterial cellulose template

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• Porous scaffold prepared from α′L-Dicalcium silicate doped with phosphorus for bone grafts

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• Electrospun polymeric nanofibres as wound dressings: A review.

  2018influential reference
• Fabrication and investigation of silica nanofibers via electrospinning.

  2018cited by this paper
• Different Methods for Nanofiber Design and Fabrication

  2018cited by this paper
• One year in review 2018: progress in osteoporosis treatment.

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• Fabrication and Characterization of Strontium-Substituted Hydroxyapatite-CaO-CaCO3 Nanofibers with a Mesoporous Structure as Drug Delivery Carriers

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• Fabrication and Characteristics of Porous Hydroxyapatite-CaO Composite Nanofibers for Biomedical Applications

  2018influential reference
• Microwave-Induced Plasma-In-Liquid Process for Nanoparticle Production

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• Recent advances on antimicrobial wound dressing: A review.

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• Fabrication, characterization and osteoblast responses of poly (octanediol citrate)/bioglass nanofiber composites.

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• Electrospun Nanofibers: New Concepts, Materials, and Applications.

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• Ceramic nanofiber composites

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• Effects of Ca/P molar ratios on regulating biological functions of hybridized carbon nanofibers containing bioactive glass nanoparticles

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• In vitro degradation and cytocompatibility of g-MgO whiskers/PLLA composites

  2017influential reference
• Nanofiber technology: current status and emerging developments

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• Nanotechnology: A Promising Tool Towards Wound Healing.

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• Sacrificial template method for the synthesis of three-dimensional nanofibrous 58S bioglass scaffold and its in vitro bioactivity and cell responses

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• Development of fish collagen/bioactive glass/chitosan composite nanofibers as a GTR/GBR membrane for inducing periodontal tissue regeneration

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• 3D bioactive composite scaffolds for bone tissue engineering

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• FIBROUS SILICA-HYDROXYAPATITE COMPOSITE BY ELECTROSPINNING

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• Diabetes and Aging: Unique Considerations and Goals of Care

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• Preparation, structural characterization, and in vitro cell studies of three-dimensional SiO2-CaO binary glass scaffolds built ofultra-small nanofibers.

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• Binary Doping of Strontium and Copper Enhancing Osteogenesis and Angiogenesis of Bioactive Glass Nanofibers while Suppressing Osteoclast Activity.

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• Carbon Nanofiber/Polycaprolactone/Mineralized Hydroxyapatite Nanofibrous Scaffolds for Potential Orthopedic Applications.

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• β-Tricalcium phosphate nanofiber scaffolds with fine unidirectional grains

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• High mechanical strength bioactive wollastonite bioceramics sintered from nanofibers

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• Electrospun cerium and gallium-containing silicate based 13-93 bioactive glass fibers for biomedical applications

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• Wet Spinning and Drawing of Human Recombinant Collagen.

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• Skin Infections in Diabetes: A Review

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• Rapid production of bioactive hydroxyapatite fibers via electroblowing

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• Preparation of Nanofibrous Structure of Mesoporous Bioactive Glass Microbeads for Biomedical Applications

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• Constructing a highly bioactive 3D nanofibrous bioglass scaffold via bacterial cellulose-templated sol-gel approach

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• Handbook of Bioceramics and Biocomposites

  2016cited by this paper
• Hierarchical porous hydroxyapatite fibers with a hollow structure as drug delivery carriers

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• Advanced Structural Ceramics

  2016cited by this paper
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• Porous SiO2 nanofiber grafted novel bioactive glass-ceramic coating: A structural scaffold for uniform apatite precipitation and oriented cell proliferation on inert implant.

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• The effect of submicron bioactive glass particles on in vitro osteogenesis

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• Electrospun metal–organic framework-based nanofibers with natural therapeutic agents for enhanced diabetic wound healing

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• Multifunctional scaffold integrating chemo/photothermal therapy and bone defect reconstruction for osteosarcoma: An in vitro evaluation.

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• Bioglasses Versus Bioactive Calcium Phosphate Derivatives as Advanced Ceramics in Tissue Engineering: Comparative and Comprehensive Study, Current Trends, and Innovative Solutions

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• Characterization of a new triaxial nanofiber membrane and osteogenic differentiation capacity of human bone marrow mesenchymal stem cells for bone repair

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• Calcium Phosphate Apatite Filament Co-Wrapped With Perforated Electrospun Sheet of Phosphorylated Chitosan-A Bioinspired Approach Toward Bone Graft Substitute.

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• Emerging nanotechnologies in wound care: The role of metal and polymeric nanocomposites in enhancing healing and combating infections.

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• Nanomaterial-enabled drug transport systems: a comprehensive exploration of current developments and future avenues in therapeutic delivery

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• Nanotechnology invigorated drug delivery and tissue engineering strategies for the management of diabetic foot ulcers: Therapeutic approaches and clinical applications

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• TiO2/SiO2 spiral crimped Janus fibers engineered for stretchable ceramic membranes with high-temperature resistance.

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• Nanotechnology development in surgical applications: recent trends and developments

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• Emerging perspectives on 3D printed bioreactors for clinical translation of engineered and bioprinted tissue constructs.

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• Microbial‐Enabled Photosynthetic Oxygenation for Disease Treatment

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• Wound healing strategies based on nanoparticles incorporated in hydrogel wound patches

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• Hydrothermally reinforcing hydroxyaptatite and bioactive glass on carbon nanofiber scafold for bone tissue engineering

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