Title: Jealous protons sour another happy marriage; the story of how TRPV5 and PI(4,5)P2 split up.

TRPV5 is a highly selective calcium channel that finetunes urinary calcium excretion by reabsorbing calcium from the pro-urine. New structural findings show how PTH and pH control TRPV5 activity by altering the binding of endogenous ligands calmodulin and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2).

• Publication year

  2022

• Venue

  Cell Calcium

• Publication date

  2022-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.ceca.2022.102609PMID 35667882
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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