Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Nature Genetics

• Publication date

  1996-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/ng1196-277PMID 8896556
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Expanded polyglutamine in the Machado–Joseph disease protein induces cell death in vitro and in vivo

  1996cited by this paper
• Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2

  1996cited by this paper
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  1996cited by this paper
• Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats

  1996cited by this paper
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• Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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• Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

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• Direct detection of expanded (CAG/CTG) repeats in the myotonin-protein kinase genes of myotonic dystrophy patients using a high-stringency hybridization method.

  1995cited by this paper
• Molecular cloning of a full-length cDNA for dentatorubral-pallidoluysian atrophy and regional expressions of the expanded alleles in the CNS.

  1995cited by this paper
• Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli

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• CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

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• Autosomal dominant cerebellar ataxia with retinal degeneration

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• Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p

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• Unstable expansion of CAG repeat in hereditary dentatorubral–pallidoluysian atrophy (DRPLA)

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• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

  1993cited by this paper
• Chromosomal assignment of the second locus for autosomal dominant cerebellar ataxia (SCA2) to chromosome 12q23–24.1

  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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• Anticipation in bipolar affective disorder.

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• Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I

  1993cited by this paper
• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

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• supplemental information

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