Celiac disease: from oral tolerance to intestinal inflammation, autoimmunity and lymphomagenesis

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Mucosal Immunology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/mi.2008.75PMID 19079330
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gluten-sensitive enteropathy.

  2022cited by this paper
• Tissue transglutaminase in celiac disease: role of autoantibodies

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• Presentation and long-term follow-up of refractory celiac disease: comparison of type I with type II.

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• Immunoglobulin A Anti-tissue Transglutaminase Antibody Deposits in the Small Intestinal Mucosa of Children With No Villous Atrophy

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• Review article: future research on coeliac disease – a position report from the European multistakeholder platform on coeliac disease (CDEUSSA)

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• Mechanisms of epithelial translocation of the α2-gliadin-33mer in coeliac sprue

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• Parallels between Pathogens and Gluten Peptides in Celiac Sprue

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• Translational Mini‐Review Series on the Immunogenetics of Gut Disease: Immunogenetics of coeliac disease

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• The cytokine interleukin 21: a new player in coeliac disease?

  2008cited by this paper
• Dependence of antibody-mediated presentation of antigen on FcRn

  2008cited by this paper
• Transepithelial Transport and Enzymatic Detoxification of Gluten in Gluten-Sensitive Rhesus Macaques

  2008cited by this paper
• Gliadin activates HLA class I-restricted CD8+ T cells in celiac disease intestinal mucosa and induces the enterocyte apoptosis.

  2008cited by this paper
• Coeliac disease‐specific autoantibodies targeted against transglutaminase 2 disturb angiogenesis

  2008cited by this paper
• Incidence of autoimmune diseases in celiac disease: protective effect of the gluten-free diet.

  2008cited by this paper
• A Non-Human Primate Model for Gluten Sensitivity

  2008cited by this paper
• Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3.

  2008cited by this paper
• Extracellular Transglutaminase 2 Is Catalytically Inactive, but Is Transiently Activated upon Tissue Injury

  2008cited by this paper
• Newly identified genetic risk variants for celiac disease related to the immune response

  2008cited by this paper
• Small intestinal CD8 + TCRγδ + NKG2A + intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease

  2008cited by this paper
• Infiltration of forkhead box P3‐expressing cells in small intestinal mucosa in coeliac disease but not in type 1 diabetes

  2008cited by this paper
• Intracellular Interaction of Interleukin-15 with Its Receptor α during Production Leads to Mutual Stabilization and Increased Bioactivity*

  2008cited by this paper
• Large-Scale Characterization of Natural Ligands Explains the Unique Gluten-Binding Properties of HLA-DQ21

  2008cited by this paper
• Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families

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• Vitamin effects on the immune system: vitamins A and D take centre stage

  2008cited by this paper
• Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease

  2008cited by this paper
• Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease.

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• Adult celiac disease with severe or partial villous atrophy: a comparative study.

  2008cited by this paper
• Combination enzyme therapy for gastric digestion of dietary gluten in patients with celiac sprue.

  2007cited by this paper
• Interleukin 21 contributes to the mucosal T helper cell type 1 response in coeliac disease

  2007cited by this paper
• Gliadin Regulates the NK-Dendritic Cell Cross-Talk by HLA-E Surface Stabilization1

  2007cited by this paper
• Cutting Edge: Distinct NK Receptor Profiles Are Imprinted on CD8 T Cells in the Mucosa and Periphery during the Same Antigen Challenge: Role of Tissue-Specific Factors1

  2007cited by this paper
• Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease.

  2007cited by this paper
• Structure-based design of alpha-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2.

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• NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice

  2007cited by this paper
• TGFbeta signalling in control of T-cell-mediated self-reactivity.

  2007cited by this paper
• Cutting Edge: Distinct NK receptor profiles are imprinted on CD8 T cells in the mucosa and periphery during the same antigen challenge: role of tissue-specific factors.

  2007cited by this paper
• Celiac disease: pathogenesis of a model immunogenetic disease.

  2007cited by this paper
• TGFβ signalling in control of T-cell-mediated self-reactivity

  2007cited by this paper
• Cyclic and dimeric gluten peptide analogues inhibiting DQ2-mediated antigen presentation in celiac disease.

  2007cited by this paper
• Gliadin Peptides Activate Blood Monocytes from Patients with Celiac Disease

  2007cited by this paper
• Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the FOXP3 gene.

  2007cited by this paper
• Survival in refractory coeliac disease and enteropathy-associated T-cell lymphoma: retrospective evaluation of single-centre experience

  2007cited by this paper
• Inhibition of TGF-beta signaling by IL-15: a new role for IL-15 in the loss of immune homeostasis in celiac disease.

  2007cited by this paper
• Chemistry of gluten proteins.

  2007cited by this paper
• Long-term follow-up of 61 coeliac patients diagnosed in childhood: evolution toward latency is possible on a normal diet

  2007cited by this paper
• IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes1

  2007cited by this paper
• A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

  2007cited by this paper
• Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

  2007cited by this paper
• Interleukin-21: a new modulator of immunity, infection, and cancer.

  2007cited by this paper
• Celiac disease--sandwiched between innate and adaptive immunity.

  2006cited by this paper
• Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming1

  2006cited by this paper
• Numbers of T cell receptor ( TCR ) a + but not of TcR yb + intraepithelial lymphocytes correlate with the grade of villous atrophy in coeliac patients on a long term normal diet

  2006cited by this paper
• Human leukocyte antigen-DQ2 homozygosity and the development of refractory celiac disease and enteropathy-associated T-cell lymphoma.

  2006cited by this paper
• A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells.

  2006cited by this paper
• In Celiac Disease, a Subset of Autoantibodies against Transglutaminase Binds Toll-Like Receptor 4 and Induces Activation of Monocytes

  2006cited by this paper
• FOXP3 polymorphisms in type 1 diabetes and coeliac disease.

  2006cited by this paper
• Adulthood-onset celiac disease is associated with intercellular adhesion molecule-1 (ICAM-1) gene polymorphism.

  2006cited by this paper
• The role of NF-kappaB, IRF-1, and STAT-1alpha transcription factors in the iNOS gene induction by gliadin and IFN-gamma in RAW 264.7 macrophages.

  2006cited by this paper
• Oral proteases: a new approach to managing coeliac disease

  2006cited by this paper
• Gliadin Stimulation of Murine Macrophage Inflammatory Gene Expression and Intestinal Permeability Are MyD88-Dependent: Role of the Innate Immune Response in Celiac Disease1

  2006cited by this paper
• Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor.

  2006cited by this paper
• Rotavirus Infection Frequency and Risk of Celiac Disease Autoimmunity in Early Childhood: A Longitudinal Study

  2006cited by this paper
• NKG2 receptor-mediated regulation of effector CTL functions in the human tissue microenvironment.

  2006cited by this paper
• IL-21 Down-Regulates NKG2D/DAP10 Expression on Human NK and CD8+ T Cells1

  2006cited by this paper
• IL-15/IL-15 receptor biology: a guided tour through an expanding universe.

  2006cited by this paper
• Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease.

  2006cited by this paper
• Growth factor-like activity of gliadin, an alimentary protein: implications for coeliac disease

  2006cited by this paper
• Reprogramming of CTLs into natural killer–like cells in celiac disease

  2006cited by this paper
• Refractory coeliac disease.

  2005cited by this paper
• Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function

  2005cited by this paper
• Coeliac disease

  2005cited by this paper
• Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

  2005cited by this paper
• Gliadin Fragments Induce Phenotypic and Functional Maturation of Human Dendritic Cells1

  2005cited by this paper
• The role of TCR stimulation and TGF‐β in controlling the expression of CD94/NKG2A receptors on CD8 T cells

  2005cited by this paper
• Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease

  2005cited by this paper
• Unexpected role of surface transglutaminase type II in celiac disease.

  2005cited by this paper
• The role of NF-κB, IRF-1, and STAT-1α transcription factors in the iNOS gene induction by gliadin and IFN-γ in RAW 264.7 macrophages

  2005cited by this paper
• Small-bowel mucosal transglutaminase 2-specific IgA deposits in coeliac disease without villous atrophy: A prospective and randomized clinical study

  2005cited by this paper
• Immunoglobulin, complement and epidermal transglutaminase deposition in the cutaneous vessels in dermatitis herpetiformis

  2005cited by this paper
• Refining the Rules of Gliadin T Cell Epitope Binding to the Disease-Associated DQ2 Molecule in Celiac Disease: Importance of Proline Spacing and Glutamine Deamidation1

  2005cited by this paper
• Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect

  2005cited by this paper
• T-cell aj 3 + and yS 3 deficient mice display abnormal but distinct phenotypes toward a natural , widespread infection of the intestinal epithelium

  2005cited by this paper
• Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

  2004cited by this paper
• Adaptive changes of duodenal iron transport proteins in celiac disease.

  2004cited by this paper
• IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.

  2004cited by this paper
• A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease.

  2004cited by this paper
• A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice.

  2004cited by this paper
• Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease.

  2004cited by this paper
• Antigen Presentation to Celiac Lesion-Derived T Cells of a 33-Mer Gliadin Peptide Naturally Formed by Gastrointestinal Digestion1

  2004cited by this paper
• Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

  2004cited by this paper
• IL-15/IL-15Rα-mediated avidity maturation of memory CD8 + T cells

  2004cited by this paper
• Presence of Bacteria and Innate Immunity of Intestinal Epithelium in Childhood Celiac Disease

  2004cited by this paper
• Gluten-free diet, chromosomal abnormalities, and cancer risk in coeliac disease.

  2004cited by this paper
• Celiac Disease Association with CD8+ T Cell Responses: Identification of a Novel Gliadin-Derived HLA-A2-Restricted Epitope1

  2003cited by this paper
• The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses

  2003cited by this paper
• Constitutive activation of the signal transducer and activator of transcription pathway in celiac disease lesions.

  2003cited by this paper
• Refractory coeliac sprue is a diffuse gastrointestinal disease

  2003cited by this paper
• Alterations of the intestinal transport and processing of gliadin peptides in celiac disease.

  2003cited by this paper
• Is Candida albicans a trigger in the onset of coeliac disease?

  2003cited by this paper
• Roles of the NKG2D immunoreceptor and its ligands

  2003cited by this paper

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