Molecular mechanism of growth hormone action.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Annual Review of Physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1146/ANNUREV.PH.58.030196.001155PMID 8815791
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mediation of Growth Hormone-dependent Transcriptional Activation by Mammary Gland Factor/Stat 5 (*)

  1995cited by this paper
• Growth Hormone Stimulates the Tyrosine Phosphorylation of the Insulin Receptor Substrate-1 and Its Association with Phosphatidylinositol 3-Kinase in Primary Adipocytes (*)

  1995cited by this paper
• Characterization of deoxyribonucleic acid-protein interactions at a growth hormone-inducible nuclease hypersensitive site in the rat insulin-like growth factor-I gene.

  1995cited by this paper
• Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription.

  1995cited by this paper
• Effects of growth hormone antagonists on 3T3-F442A preadipocyte differentiation.

  1995cited by this paper
• Activation of Acute Phase Response Factor (APRF)/Stat3 Transcription Factor by Growth Hormone (*)

  1995cited by this paper
• Intracellular Tyrosine Residues of the Human Growth Hormone Receptor Are Not Required for the Signaling of Proliferation or Jak-STAT Activation (*)

  1995cited by this paper
• Requirement of Tyrosine Residues 333 and 338 of the Growth Hormone (GH) Receptor for Selected GH-stimulated Function (*)

  1995cited by this paper
• In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3.

  1995cited by this paper
• The Conserved Box 1 Motif of Cytokine Receptors Is Required for Association with JAK Kinases (*)

  1995cited by this paper
• Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

  1995cited by this paper
• Growth Hormone-promoted Tyrosyl Phosphorylation of SHC Proteins and SHC Association with Grb2 (*)

  1995cited by this paper
• Regions of the JAK2 Tyrosine Kinase Required for Coupling to the Growth Hormone Receptor (*)

  1995cited by this paper
• Amino acids of the human growth hormone receptor that are required for proliferation and Jak-STAT signaling.

  1995cited by this paper
• Growth Hormone, Interferon-γ, and Leukemia Inhibitory Factor Promoted Tyrosyl Phosphorylation of Insulin Receptor Substrate-1 (*)

  1995cited by this paper
• Early responses of trans-activating factors to growth hormone in preadipocytes: differential regulation of CCAAT enhancer-binding protein-beta (C/EBP beta) and C/EBP delta.

  1995cited by this paper
• Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor.

  1994cited by this paper
• Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2

  1994cited by this paper
• Lymphocyte responses and cytokines.

  1994cited by this paper
• Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

  1994cited by this paper
• Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors.

  1994cited by this paper
• Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells

  1994cited by this paper
• Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no changes in deoxyribonucleic acid-protein interactions within the second promoter.

  1994cited by this paper
• Growth hormone stimulates tyrosine phosphorylation of insulin receptor substrate-1.

  1994cited by this paper
• Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

  1994cited by this paper
• Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase.

  1994cited by this paper
• Growth hormone specifically regulates serine protease inhibitor gene transcription via gamma-activated sequence-like DNA elements.

  1994cited by this paper
• Ligand‐induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91).

  1994cited by this paper
• Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.

  1994cited by this paper
• Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91.

  1994cited by this paper
• Identification of Intracellular Domains in the Growth Hormone Receptor Involved in Signal Transduction

  1994cited by this paper
• Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation

  1994cited by this paper
• Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase.

  1994cited by this paper
• The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements.

  1994cited by this paper
• Distinct cytoplasmic regions of the growth hormone receptor are required for activation of JAK2, mitogen-activated protein kinase, and transcription.

  1994cited by this paper
• Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

  1994cited by this paper
• In vitro mutagenesis of growth hormone receptor Asn-linked glycosylation sites.

  1994cited by this paper
• Cloning of a murine IL‐11 receptor alpha‐chain; requirement for gp130 for high affinity binding and signal transduction.

  1994cited by this paper
• PI-3-kinase inhibitor Wortmannin blocks the insulin-like effects of growth hormone in isolated rat adipocytes.

  1994cited by this paper
• Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.

  1994cited by this paper
• Growth hormone regulation of lipid metabolism in cells transfected with growth hormone receptor cDNA.

  1994cited by this paper
• The extended box 2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells.

  1994cited by this paper
• Cytoplasmic sequences of the growth hormone receptor necessary for signal transduction.

  1994cited by this paper
• Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no alterations in deoxyribonucleic acid-protein interactions within the major promoter.

  1994cited by this paper
• Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions.

  1994cited by this paper
• Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells.

  1994cited by this paper
• Signal Transduction by the Growth Hormone Receptor

  1994cited by this paper
• Human growth hormone increases cytosolic free calcium in cultured human IM-9 lymphocytes: a novel mechanism of growth hormone transmembrane signalling.

  1994cited by this paper
• Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

  1994cited by this paper
• Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor.

  1993cited by this paper
• The regulation by growth hormone of lipoprotein lipase gene expression is mediated by c-fos protooncogene.

  1993cited by this paper
• Extracellular signals and reversible protein phosphorylation: what to Mek of it all.

  1993cited by this paper
• The growth hormone/prolactin receptor family.

  1993cited by this paper
• A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity

  1993cited by this paper
• Human growth hormone (GH) receptor is characterized as the 134-kilodalton tyrosine-phosphorylated protein activated by GH treatment in IM-9 cells.

  1993cited by this paper
• Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase.

  1993cited by this paper
• Mutational analysis of the intracellular domain of the human growth hormone receptor.

  1993cited by this paper
• Stimulation of tyrosine phosphorylation in human cells by activation of the growth hormone receptor.

  1993cited by this paper
• Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

  1993cited by this paper
• Evidence for involvement of the growth hormone receptor-associated tyrosine kinase in actions of growth hormone.

  1993cited by this paper
• The proline-rich motif (PRM): a novel feature of the cytokine/hematopoietin receptor superfamily.

  1993cited by this paper
• The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain.

  1993cited by this paper
• Growth hormone (GH) stimulates insulin-like growth factor-I (IGF-I) and IGF-I-binding protein-3, but not GH receptor gene expression in livers of juvenile rats.

  1993cited by this paper
• The serum response element can mediate induction of c-fos by growth hormone.

  1993cited by this paper
• Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by growth hormone in rat white adipose tissue.

  1993cited by this paper
• Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

  1993cited by this paper
• The mitogen-activated protein kinase signal transduction pathway.

  1993cited by this paper
• JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin.

  1993cited by this paper
• SH2 and SH3 domains.

  1993cited by this paper
• Activation of ternary complex factor Elk‐1 by MAP kinases.

  1993cited by this paper
• A receptor for interleukin 10 is related to interferon receptors.

  1993cited by this paper
• Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation.

  1993cited by this paper
• Growth hormone activates mitogen-activated protein kinase and S6 kinase and promotes intracellular tyrosine phosphorylation in 3T3-F442A preadipocytes.

  1992cited by this paper
• Growth hormone stimulates the tyrosine phosphorylation of 42- and 45-kDa ERK-related proteins.

  1992cited by this paper
• Stimulation by growth hormone of MAP kinase activity in 3T3-F442A fibroblasts.

  1992cited by this paper
• JAK2, a third member of the JAK family of protein tyrosine kinases.

  1992cited by this paper
• Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

  1992cited by this paper
• Growth hormone (GH) induction of tyrosine phosphorylation and activation of mitogen-activated protein kinases in cells transfected with rat GH receptor cDNA.

  1992cited by this paper
• The serum response element.

  1992cited by this paper
• Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.

  1992cited by this paper
• Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.

  1992cited by this paper
• Growth hormone increases intracellular free calcium in rat adipocytes: correlation with actions on carbohydrate metabolism.

  1992cited by this paper
• Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo.

  1992cited by this paper
• Rational design of potent antagonists to the human growth hormone receptor.

  1992cited by this paper
• Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase.

  1992cited by this paper
• Hepatic steroid hydroxylating enzymes are controlled by the sexually dimorphic pattern of growth hormone secretion in normal and dwarf rats

  1992cited by this paper
• Cellular mechanism of the insulin-like effect of growth hormone in adipocytes. Rapid translocation of the HepG2-type and adipocyte/muscle glucose transporters.

  1992cited by this paper
• Expression and regulation of growth hormone (GH) receptor messenger ribonucleic acid (mRNA) in rat adipose tissue, adipocytes, and adipocyte precursor cells: GH regulation of GH receptor mRNA.

  1991cited by this paper
• Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors.

  1991cited by this paper
• Recurrent nonsense mutations in the growth hormone receptor from patients with Laron dwarfism.

  1991cited by this paper
• Antibodies to cytoplasmic sequences of cloned liver growth hormone (GH) receptors recognize GH receptors associated with tyrosine kinase activity.

  1991cited by this paper
• Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule.

  1991cited by this paper
• Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

  1991cited by this paper
• Refractoriness to growth hormone is associated with increased intracellular calcium in rat adipocytes.

  1991cited by this paper
• Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

  1991cited by this paper
• The prolactin/growth hormone receptor family.

  1991cited by this paper
• Growth hormone induces expression of c-jun and jun B oncogenes and employs a protein kinase C signal transduction pathway for the induction of c-fos oncogene expression.

  1991cited by this paper
• A role for protein kinases in the growth hormone regulation of cytochrome P4502C12 and insulin-like growth factor-I messenger RNA expression in primary adult rat hepatocytes.

  1991cited by this paper
• ERKs, extracellular signal-regulated MAP-2 kinases.

  1991cited by this paper
• Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

  1991cited by this paper

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