Dietary wine phenolics catechin, quercetin, and resveratrol efficiently protect hypercholesterolemic hamsters against aortic fatty streak accumulation.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Agricultural and Food Chemistry

• Publication date

  2005-02-17

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/JF048177QPMID 15769129
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phenolics from commercialized grape extracts prevent early atherosclerotic lesions in hamsters by mechanisms other than antioxidant effect.

  2004cited by this paper
• Vascular effects of wine polyphenols.

  2004cited by this paper
• Does systemic inflammation trigger local exercise-induced oxidative stress in COPD?

  2004cited by this paper
• Dealcoholized red wine decreases atherosclerosis in apolipoprotein E gene-deficient mice independently of inhibition of lipid peroxidation in the artery wall.

  2004cited by this paper
• Vascular protection by dietary polyphenols.

  2004cited by this paper
• Hydroxycinnamic acids do not prevent aortic atherosclerosis in hypercholesterolemic golden Syrian hamsters.

  2004cited by this paper
• Profound negative regulatory effects by resveratrol on vascular smooth muscle cells: a role of p53-p21(WAF1/CIP1) pathway.

  2003cited by this paper
• Human apo A-I and rat transferrin are the principal plasma proteins that bind wine catechins.

  2002cited by this paper
• Red wine phenolic compounds reduce plasma lipids and apolipoprotein B and prevent early aortic atherosclerosis in hypercholesterolemic golden Syrian hamsters (Mesocricetus auratus).

  2002cited by this paper
• Comparison of red wine extract and polyphenol constituents on endothelin-1 synthesis by cultured endothelial cells.

  2002cited by this paper
• Moderate Wine and Alcohol Consumption: Beneficial Effects on Cardiovascular Disease

  2001cited by this paper
• Antioxidant effects of phenolic rye (Secale cereale L.) extracts, monomeric hydroxycinnamates, and ferulic acid dehydrodimers on human low-density lipoproteins.

  2001cited by this paper
• Red wine, dealcoholized red wine, and especially grape juice, inhibit atherosclerosis in a hamster model.

  2001cited by this paper
• Genistein prevents the glucose autoxidation mediated atherogenic modification of low density lipoprotein

  2001cited by this paper
• Induction of Oxidatively Modified Proteins in Skeletal Muscle by Electrical Stimulation and Its Suppression by Dietary Supplementation of (-)-Epigallocatechin Gallate

  2000cited by this paper
• Does a glass of red wine improve endothelial function?

  2000cited by this paper
• Plant-derived phenolic antioxidants.

  2000cited by this paper
• Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids.

  1999cited by this paper
• Comparative study of polyphenol scavenging activities assessed by different methods.

  1999cited by this paper
• Cardioprotection of red wine: role of polyphenolic antioxidants.

  1999cited by this paper
• Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease.

  1999cited by this paper
• Inhibitory effect of quercetin metabolites and their related derivatives on copper ion-induced lipid peroxidation in human low-density lipoprotein.

  1999cited by this paper
• Structural dependence of flavonoid interactions with Cu2+ ions: implications for their antioxidant properties.

  1998cited by this paper
• Determination of Advanced Glycation End Products in Serum by Fluorescence Spectroscopy and Competitive ELISA

  1997cited by this paper
• Wine as a biological fluid: History, production, and role in disease prevention

  1997cited by this paper
• Erythropoietin and oxidative stress in haemodialysis: beneficial effects of vitamin E supplementation.

  1997cited by this paper
• Resveratrol inhibits metal ion-dependent and independent peroxidation of porcine low-density lipoproteins.

  1997cited by this paper
• Advanced oxidation protein products as a novel marker of oxidative stress in uremia.

  1996cited by this paper
• Alcohol consumption, serum low density lipoprotein cholesterol concentration, and risk of ischaemic heart disease: six year follow up in the Copenhagen male study

  1996cited by this paper
• Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits?

  1996cited by this paper
• Phenolic content of various beverages determines the extent of inhibition of human serum and low-density lipoprotein oxidation in vitro: identification and mechanism of action of some cinnamic acid derivatives from red wine.

  1996cited by this paper
• The relative antioxidant activities of plant-derived polyphenolic flavonoids.

  1995cited by this paper
• The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.

  1995cited by this paper
• Antiplatelet activity of synthetic and natural resveratrol in red wine.

  1995cited by this paper
• Total antioxidant status in plasma and body fluids.

  1994cited by this paper
• Actions of flavonoids and coumarins on lipoxygenase and cyclooxygenase.

  1994cited by this paper
• Role of flavonoids and iron chelation in antioxidant action.

  1994cited by this paper
• The correlation between active oxygens scavenging and antioxidative effects of flavonoids.

  1994cited by this paper
• Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine.

  1993cited by this paper
• Mesorectal excision for rectal cancer.

  1993cited by this paper
• Inhibition of human LDL oxidation by resveratrol.

  1993cited by this paper
• Wine, alcohol, platelets, and the French paradox for coronary heart disease

  1992cited by this paper
• Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages.

  1990cited by this paper
• Quantification of high-density-lipoprotein cholesterol in plasma from hamsters by differential precipitation.

  1990cited by this paper
• Assays for superoxide dismutase based on autoxidation of hematoxylin.

  1990cited by this paper
• Determination of superoxide dismutase activity by purely chemical system based on NAD(P)H oxidation.

  1990cited by this paper
• Quantitation of oil red O staining of the aorta in hypercholesterolemic rats.

  1989cited by this paper
• Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.

  1989cited by this paper
• Immunoturbidimetric assays of apolipoproteins A, AI, AII, and B in serum.

  1986cited by this paper
• Measurement of protein using bicinchoninic acid.

  1985cited by this paper
• Assays of lipoxygenase, 1,4-pentadiene fatty acids, and O2 concentrations: chemiluminescence methods.

  1984cited by this paper
• Catalase in vitro.

  1984cited by this paper
• Influence of ashing techniques on the analysis of trace elements in animal tissue

  1981cited by this paper

• Resveratrol suppresses hepatic fatty acid synthesis and increases fatty acid β-oxidation via the microRNA-33/SIRT6 signaling pathway

  2024cites this paper
• Beneficial effects of flavonoids on animal models of atherosclerosis: A systematic review and meta-analysis

  2023cites this paper
• Effects of beer, wine, and baijiu consumption on non-alcoholic fatty liver disease: Potential implications of the flavor compounds in the alcoholic beverages

  2023cites this paper
• New supramolecular complex of quercetin with triterpene glycoside alpha-hederin

  2022cites this paper
• Ecogeographic Conditions Dramatically Affect Trans-Resveratrol and Other Major Phenolics’ Levels in Wine at a Semi-Arid Area

  2022cites this paper
• Influence of Different Defoliation Timings on Quality and Phenolic Composition of the Wines Produced from the Serbian Autochthonous Variety Prokupac (Vitis vinifera L.)

  2022cites this paper
• Changes in Major Phenolic Compounds of Seeds, Skins, and Pulps from Various Vitis spp. and the Effect of Powdery and Downy Mildew Diseases on Their Levels in Grape Leaves

  2021cites this paper
• Date Palm Bioactive Compounds: Nutraceuticals, Functional Nutrients, and Pharmaceuticals

  2021cites this paper
• Unripe grapes: an overview of the composition, traditional and innovative applications, and extraction methods of a promising waste of viticulture

  2021cites this paper
• Characterisation of Extracts Obtained from Unripe Grapes and Evaluation of Their Potential Protective Effects against Oxidation of Wine Colour in Comparison with Different Oenological Products

  2021cites this paper
• Improvement in antioxidant activities and cholesterol secretion inhibition abilities of black raspberry extracts upon maturation

  2020cites this paper
• Pistacia lentiscus extract enhances mammary epithelial cells’ productivity by modulating their oxidative status

  2020cites this paper
• Comparison of protective effects between oat β-glucan and phenol-rich extracts in hyperlipidemic ICR mice

  2020cites this paper
• Herbal Medicine for Slowing Aging and Aging-Associated Conditions: Efficacy, Mechanisms, and Safety.

  2020cites this paper
• Could grape-based food supplements prevent the development of chronic kidney disease?

  2020cites this paper
• Dietary Grape Pomace Supplementation in Dairy Cows: Effect on Nutritional Quality of Milk and Its Derived Dairy Products

  2020cites this paper
• Grape Polyphenolics

  2020cites this paper
• The use of catechins in CHO cell media for the improvement of monoclonal antibody yields and a reduction of acidic species.

  2020cites this paper
• Dates (Phoenix Dactylifera) and Date Vinegar: Preventive Role against Various Diseases and Related in Vivo Mechanisms

  2020cites this paper
• Regulation of apolipoprotein B by natural products and nutraceuticals: a comprehensive review.

  2020cites this paper
• Medicinal plants and bioactive natural compounds as inhibitors of HMG‐CoA reductase: A literature review

  2020cites this paper
• Total phenolic, flavonoid content and metabolite profiling of methanol extract of date (Phoenix dactylifera) seeds by LC-QTOF-MS

  2020cites this paper
• Molecular complex of quercetin with hederasaponin C

  2020cites this paper
• Chemical characterization and anti‐breast cancer effects of silver nanoparticles using Phoenix dactylifera seed ethanolic extract on 7,12‐Dimethylbenz[a] anthracene‐induced mammary gland carcinogenesis in Sprague Dawley male rats

  2019cites this paper
• Activity profiling of Serbian and some other European Merlot wines in inflammation and oxidation processes.

  2019cites this paper
• Dietary natural products as emerging lipoprotein(a)‐lowering agents

  2019cites this paper
• Date Palm (Phoenix dactylifera): Novel Findings and Future Directions for Food and Drug Discovery.

  2019cites this paper
• Vectisol Formulation Enhances Solubility of Resveratrol and Brings Its Benefits to Kidney Transplantation in a Preclinical Porcine Model

  2019cites this paper
• Molecular complex of quercetin with glycyram

  2019cites this paper
• Role of Resveratrol on Indoxyl Sulfate-Induced Endothelial Hyperpermeability via Aryl Hydrocarbon Receptor (AHR)/Src-Dependent Pathway

  2019cites this paper
• Effect of grape seed extract on maternal toxicity and in utero development in mice treated with zearalenone

  2019cites this paper
• Anti-Atherosclerotic Effect of a Polyphenol-Rich Ingredient, Oleactiv®, in a Hypercholesterolemia-Induced Golden Syrian Hamster Model

  2018cites this paper
• Effects of Talinum triangulare leaf flavonoid extract on streptozotocin‐induced hyperglycemia and associated complications in rats

  2018cites this paper
• Antiaging Interventions: An Insight into Polyphenols and Brain Aging

  2018cites this paper
• Screening and development of natural compounds as tools to improve IgG production and quality in recombinant CHO cell culture

  2018cites this paper
• Regulatory Roles of Flavonoids on Inflammasome Activation during Inflammatory Responses

  2018cites this paper
• The effects of wine consumption on cardiovascular disease and associated risk factors: a narrative review

  2018cites this paper
• Phenolic Compounds and Antioxidant Activity in Grape Juices: A Chemical and Sensory View

  2018cites this paper
• A Novel Fluorimetric Method to Evaluate Red Wine Antioxidant Activity

  2018cites this paper
• Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis

  2017cites this paper
• Quercetin improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice fed a high-fat diet

  2017cites this paper
• Grapefruit Flavonoid Naringenin Regulates the Expression of LXRα in THP-1 Macrophages by Modulating AMP-Activated Protein Kinase.

  2017cites this paper
• Curcumin-3,4-Dichloro Phenyl Pyrazole (CDPP) overcomes curcumin's low bioavailability, inhibits adipogenesis and ameliorates dyslipidemia by activating reverse cholesterol transport.

  2017cites this paper
• The Role of Quercetin on some CardioVascular Parameters in Rats with Insulin Resistance Syndrome

  2017cites this paper
• Evaluation of different training systems on Annurca apple fruits revealed by agronomical, qualitative and NMR-based metabolomic approaches.

  2017cites this paper
• Impact of Clonal Variability on Phenolics and Radical Scavenging Activity of Grapes and Wines: A Study on the Recently Developed Merlot and Cabernet Franc Clones (Vitis vinifera L.)

  2016cites this paper
• Celastrus Orbiculatus Thunb. Reduces Lipid Accumulation by Promoting Reverse Cholesterol Transport in Hyperlipidemic Mice

  2016cites this paper
• Hypolipidemic and antiatherogenic effects of Cynara scolymus in cholesterol-fed rats

  2016cites this paper
• Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway.

  2015cites this paper
• Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes.

  2015cites this paper
• Resveratrol protects against homocysteine‐induced cell damage via cell stress response in neuroblastoma cells

  2015cites this paper
• Encapsulation of the Ethanol Extract of Garcina kola and Evaluation of Its Physicochemical Properties

  2015cites this paper
• Technological Aspects of By-Product Utilization

  2015cites this paper
• Resveratrol Supplementation Reduces Aortic Atherosclerosis and Calcification and Attenuates Loss of Aerobic Capacity in a Mouse Model of Uremia

  2014influential citation
• Resveratrol and cardiovascular health--promising therapeutic or hopeless illusion?

  2014cites this paper
• Antiartherosclerotic Effects of Plant Flavonoids

  2014cites this paper
• Effect of antioxidant potential of tropical fruit juices on antioxidant enzyme profiles and lipid peroxidation in rats.

  2014cites this paper
• The polyphenol extract from Sechium edule shoots inhibits lipogenesis and stimulates lipolysis via activation of AMPK signals in HepG2 cells.

  2014cites this paper
• Rohitukine inhibits in vitro adipogenesis arresting mitotic clonal expansion and improves dyslipidemia in vivo[S]

  2014cites this paper
• Flavone Composition and Antihypercholesterolemic and Antihyperglycemic Activities of Chrysanthemum coronarium L.

  2014cites this paper
• Protective Effect of Grape Seed and Skin Extract Against High-Fat Diet-Induced Liver Steatosis and Zinc Depletion in Rat

  2014cites this paper
• Inhibition of VEGF Signaling by Polyphenols in Relation to Atherosclerosis and Cardiovascular Disease

  2014cites this paper
• Grapevine stilbenoids: Bioavailability and neuroprotection

  2013cites this paper
• Resveratrol and related compounds as antioxidants with an allosteric mechanism of action in epigenetic drug targets.

  2013cites this paper
• Sasa quelpaertensis and p-Coumaric Acid Attenuate Oleic Acid-Induced Lipid Accumulation in HepG2 Cells

  2013cites this paper
• Resveratrol ameliorates high-glucose-induced hyperpermeability mediated by caveolae via VEGF/KDR pathway

  2013cites this paper
• Quercetin up-regulates expressions of peroxisome proliferator-activated receptor γ, liver X receptor α, and ATP binding cassette transporter A1 genes and increases cholesterol efflux in human macrophage cell line.

  2013cites this paper
• Curcumin decreases oleic acid-induced lipid accumulation via AMPK phosphorylation in hepatocarcinoma cells.

  2013cites this paper
• THE INFLUENCE OF A NEW RUTIN DERIVATIVE ON HOMOCYSTEINE, CHOLESTEROL AND TOTAL ANTIOXIDATIVE STATUS IN EXPERIMENTAL DIABETES IN RAT

  2013cites this paper
• Resveratrol administration or SIRT1 overexpression does not increase LXR signaling and macrophage-to-feces reverse cholesterol transport in vivo.

  2013cites this paper
• Antioxidant and antiapoptotic effects of proanthocyanidin and ginkgo biloba extract against doxorubicin‐induced cardiac injury in rats

  2013cites this paper
• Mulberry leaf polyphenol extracts reduced hepatic lipid accumulation involving regulation of adenosine monophosphate activated protein kinase and lipogenic enzymes

  2013cites this paper
• Pleiotropic beneficial effects of epigallocatechin gallate, quercetin and delphinidin on cardiovascular diseases associated with endothelial dysfunction.

  2013cites this paper
• Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1.

  2013cites this paper
• Effects of flavonoids on the vascular endothelium: What is known and what is next?

  2012cites this paper
• Anti-atherosclerotic effects of fruit bioactive compounds: A review of current scientific evidence

  2012cites this paper
• A dietary resveratrol-rich grape extract prevents the developing of atherosclerotic lesions in the aorta of pigs fed an atherogenic diet.

  2012cites this paper
• Efecto hipoglicemiante del extracto acuoso de las hojas de Smallanthus sonchifolius (Yacón) en pacientes con diabetes mellitus tipo 2

  2012cites this paper
• Anti-atherosclerotic effects of fruit bioactive compounds: A review of current scientific evidence

  2012cites this paper
• Vineatrol and cardiovascular disease: beneficial effects of a vine-shoot phenolic extract in a hamster atherosclerosis model.

  2012cites this paper
• Resveratrol in Cholesterol Metabolism and Atherosclerosis

  2012cites this paper
• Apple peel flavonoid- and triterpene-enriched extracts differentially affect cholesterol homeostasis in hamsters

  2012cites this paper
• Quercetin enhances ABCA1 expression and cholesterol efflux through a p38-dependent pathway in macrophages

  2012cites this paper
• Recent Patents on Biomedical Applications for the Treatment of Atherosclerosis

  2012cites this paper
• Resveratrol Exerts Dosage and Duration Dependent Effect on Human Mesenchymal Stem Cell Development

  2012cites this paper
• The Sirtuin System: The Holy Grail of Resveratrol?

  2012cites this paper
• Proatherogenic Macrophage Activities Are Targeted by the Flavonoid Quercetin

  2012cites this paper
• Dietary Antioxidants: From Micronutrients and Phytochemicals to Enzymes - Preventive Effects on Early Atherosclerosis and Obesity

  2012influential citation
• Natural products as anti-glycation agents: possible therapeutic potential for diabetic complications.

  2012cites this paper
• Antioxidant, Anti-inflammatory and Hypolipidemic Properties of Apple Flavonols

  2012cites this paper
• Modulation of endogenous antioxidant system by wine polyphenols in human disease.

  2011cites this paper
• Metabolic profiling of strawberry grape ( Vitis × labruscana cv. 'Isabella') components by nuclear magnetic resonance (NMR) and evaluation of their antioxidant and antiproliferative properties.

  2011cites this paper
• 3-Hydroxy-3-methylglutaryl coenzyme A reductase regulation by antioxidant compounds: new therapeutic tools for hypercholesterolemia?

  2011cites this paper
• A review of the chemistry and pharmacology of the date fruits (Phoenix dactylifera L.)

  2011cites this paper
• Hypocholesterolemic effects of Auricularia auricula ethanol extract in ICR mice fed a cholesterol-enriched diet

  2011cites this paper
• Inhibition of Tumor Growth by Grape Seed Extract (GSE).

  2011cites this paper
• Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study)

  2011cites this paper
• Rutin inhibits oleic acid induced lipid accumulation via reducing lipogenesis and oxidative stress in hepatocarcinoma cells.

  2011cites this paper
• Calorie restriction and resveratrol in cardiovascular health and disease.

  2011cites this paper
• Effect of resveratrol on platelet activation in hypercholesterolemic rats: CD40-CD40L system as a potential target.

  2011cites this paper