This information is current as Activation Tyrosine Kinases , Btk and Lyn , in Mast Cell Redundant and Opposing Functions of Two

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  2000

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• Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cbeta.

  2000cited by this paper
• Bruton’s Tyrosine Kinase as an Inhibitor of the Fas/CD95 Death-inducing Signaling Complex*

  1999cited by this paper
• Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1

  1999cited by this paper
• Different Protein Tyrosine Kinases Are Required for B Cell Antigen Receptor–mediated Activation of Extracellular Signal–Regulated kinase, c-Jun NH2-terminal Kinase 1, and p38 Mitogen-activated Protein Kinase

  1998cited by this paper
• Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes.

  1998cited by this paper
• Abrogation of autoimmune disease in Lyn-deficient mice by the mutation of the Btk gene.

  1998influential reference
• Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways

  1998influential reference
• Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.

  1998cited by this paper
• Phosphatidylinositol‐3,4,5‐trisphosphate (PtdIns‐3,4,5‐P3)/Tec kinase‐dependent calcium signaling pathway: a target for SHIP‐mediated inhibitory signals

  1998cited by this paper
• A Double-Edged Kinase Lyn: A Positive and Negative Regulator for Antigen Receptor–mediated Signals

  1998cited by this paper
• Inhibition of the B Cell by CD22: A Requirement for Lyn

  1998cited by this paper
• Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production

  1998influential reference
• Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway.

  1998cited by this paper
• Lyn-mediated down-regulation of B cell antigen receptor signaling: inhibition of protein kinase C activation by Lyn in a kinase-independent fashion.

  1998cited by this paper
• IgE Enhances Mouse Mast Cell FcεRI Expression In Vitro and In Vivo: Evidence for a Novel Amplification Mechanism in IgE-dependent Reactions

  1997cited by this paper
• The Unique Domain as the Site on Lyn Kinase for Its Constitutive Association with the High Affinity Receptor for IgE*

  1997cited by this paper
• Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

  1997cited by this paper
• Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity.

  1997influential reference
• Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells.

  1997cited by this paper
• Itk and Fyn Make Independent Contributions to T Cell Activation

  1997cited by this paper
• Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation.

  1997cited by this paper
• Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity.

  1997cited by this paper
• syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction.

  1997influential reference
• Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells.

  1996cited by this paper
• IgE antibody up-regulates high affinity IgE binding on murine bone marrow-derived mast cells.

  1996cited by this paper
• Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells

  1996cited by this paper
• Persistent Activation of c-Jun N-terminal Kinase 1 (JNK1) in γ Radiation-induced Apoptosis (*)

  1996cited by this paper
• A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2

  1996cited by this paper
• Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides

  1996influential reference
• Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp

  1996cited by this paper
• Regulation of Btk function by a major autophosphorylation site within the SH3 domain.

  1996cited by this paper
• Cytokine signaling through nonreceptor protein tyrosine kinases.

  1995cited by this paper
• Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice.

  1995cited by this paper
• Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation.

  1995cited by this paper
• The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases (*)

  1995cited by this paper
• Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

  1995cited by this paper
• A Requirement for Syk in the Activation of the Microtubule-associated Protein Kinase/Phospholipase A2 Pathway by FcεR1 Is Not Shared by a G Protein-coupled Receptor (*)

  1995cited by this paper
• Defective B cell development and function in Btk-deficient mice.

  1995cited by this paper
• Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

  1995cited by this paper
• New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL)

  1995cited by this paper
• Impaired expansion of mouse B cell progenitors lacking Btk.

  1995cited by this paper
• Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation.

  1994cited by this paper
• Tyrosine kinases Lyn and Syk regulate B cell receptor‐coupled Ca2+ mobilization through distinct pathways.

  1994cited by this paper
• Identification of a protein, SPY75, with repetitive helix-turn-helix motifs and an SH3 domain as a major substrate for protein tyrosine kinase(s) activated by Fc epsilon RI cross-linking.

  1994influential reference
• Src homology 2 domains of Syk and Lyn bind to tyrosine-phosphorylated subunits of the high affinity IgE receptor.

  1994cited by this paper
• THE GENE INVOLVED IN X-LINKED AGAMMAGLOBULINEMIA IS A MEMBER OF THE SRC FAMILY OF PROTEIN-TYROSINE KINASES

  1994cited by this paper
• Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor.

  1994cited by this paper
• Signal transduction by Fc receptors: the Fc&RI case

  1993cited by this paper
• Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia.

  1993cited by this paper
• Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter

  1993cited by this paper
• Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes.

  1993cited by this paper
• Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells.

  1993cited by this paper
• Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.

  1993influential reference
• Tyrosine Phosphorylation is Required for Mast Cell Activation by FcεRI Cross-Linking.

  1992cited by this paper
• Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

  1992cited by this paper
• Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent. Partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha.

  1991cited by this paper
• Studies with a monoclonal antibody to the beta subunit of the receptor with high affinity for immunoglobulin E.

  1988cited by this paper
• The role of protein kinase C in cell surface signal transduction and tumour promotion

  1984cited by this paper
• The CBA/N mouse strain: an experimental model illustrating the influence of the X-chromosome on immunity.

  1982cited by this paper
• Release of histamine from human leukocytes stimulated with the tumor-promoting phorbol diesters. I. Characterization of the response.

  1981cited by this paper
• An automated continuous-flow system for the extraction and fluorometric analysis of histamine.

  1974cited by this paper

• No citing papers are available for this paper.