Association of the Herpes Simplex Virus Type 1 Us11 Gene Product with the Cellular Kinesin Light-Chain-Related Protein PAT1 Results in the Redistribution of Both Polypeptides

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of Virology

• Publication date

  2003-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.77.17.9192-9203.2003PMID 12915535PMCID PMC187382
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Association of a Mr 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2a and premature shutoff of protein synthesis after infection with y134.5- mutants of herpes simplex virus 1

  2005cited by this paper
• Identification of a Lytic-Cycle Epstein-Barr Virus Gene Product That Can Regulate PKR Activation

  2003cited by this paper
• Gene expression and the myth of the average cell.

  2003cited by this paper
• Principles of cargo attachment to cytoplasmic motor proteins.

  2002cited by this paper
• Unique Motif for Nucleolar Retention and Nuclear Export Regulated by Phosphorylation

  2002influential reference
• Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior

  2002cited by this paper
• Herpesvirus Assembly and Egress

  2002cited by this paper
• AbetaPP, apoptosis and Alzheimer's disease.

  2002cited by this paper
• Characterization of RNA Determinants Recognized by the Arginine- and Proline-Rich Region of Us11, a Herpes Simplex Virus Type 1-Encoded Double-Stranded RNA Binding Protein That Prevents PKR Activation

  2002cited by this paper
• Herpes Simplex Virus Tegument Protein US11 Interacts with Conventional Kinesin Heavy Chain

  2002influential reference
• Function of dynein and dynactin in herpes simplex virus capsid transport.

  2002cited by this paper
• AβPP, Apoptosis and Alzheimer's disease

  2002cited by this paper
• Inhibition of PACT-Mediated Activation of PKR by the Herpes Simplex Virus Type 1 Us11 Protein

  2002cited by this paper
• mRNA Degradation by the Virion Host Shutoff (Vhs) Protein of Herpes Simplex Virus: Genetic and Biochemical Evidence that Vhs Is a Nuclease

  2002cited by this paper
• The Herpes Simplex Virus Type 1 US11 Protein Interacts with Protein Kinase R in Infected Cells and Requires a 30-Amino-Acid Sequence Adjacent to a Kinase Substrate Domain

  2002influential reference
• The Herpes Simplex Virus Type 1 US11 Protein Binds the Coterminal UL12, UL13, and UL14 RNAs and Regulates UL13 Expression In Vivo

  2002influential reference
• Egress of Alphaherpesviruses: Comparative Ultrastructural Study

  2001cited by this paper
• A role for a rat homolog of staufen in the transport of RNA to neuronal dendrites.

  2001cited by this paper
• Localization and translation of mRNA in dentrites and axons

  2001cited by this paper
• mRNA Decay during Herpesvirus Infections: Interaction between a Putative Viral Nuclease and a Cellular Translation Factor

  2001cited by this paper
• The γ-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

  2001cited by this paper
• Protein synthesis at synaptic sites on dendrites.

  2001cited by this paper
• A conserved α-herpesvirus protein necessary for axonal localization of viral membrane proteins

  2001cited by this paper
• Herpesviruses use bidirectional fast-axonal transport to spread in sensory neurons

  2001cited by this paper
• Getting the message across: the intracellular localization of mRNAs in higher eukaryotes.

  2001cited by this paper
• RNAs Extracted from Herpes Simplex Virus 1 Virions: Apparent Selectivity of Viral but Not Cellular RNAs Packaged in Virions

  2001cited by this paper
• Inhibition of PKR Activation by the Proline-Rich RNA Binding Domain of the Herpes Simplex Virus Type 1 Us11 Protein

  2000cited by this paper
• Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein.

  2000cited by this paper
• Evidence that Herpes Simplex Virus VP16 Is Required for Viral Egress Downstream of the Initial Envelopment Event

  2000cited by this paper
• Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I.

  2000cited by this paper
• A subset of viral transcripts packaged within human cytomegalovirus particles.

  2000cited by this paper
• A function for kinesin I in the posterior transport of oskar mRNA and Staufen protein.

  2000cited by this paper
• A Herpesvirus Ribosome-Associated, RNA-Binding Protein Confers a Growth Advantage upon Mutants Deficient in a GADD34-Related Function

  1999cited by this paper
• The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease

  1998cited by this paper
• The Herpes Simplex Virus US11 Protein Effectively Compensates for the γ134.5 Gene if Present before Activation of Protein Kinase R by Precluding Its Phosphorylation and That of the α Subunit of Eukaryotic Translation Initiation Factor 2

  1998cited by this paper
• Distinct domains in herpes simplex virus type 1 US11 protein mediate post-transcriptional transactivation of human T-lymphotropic virus type I envelope glycoprotein gene expression and specific binding to the Rex responsive element.

  1998cited by this paper
• The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.

  1998cited by this paper
• PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.

  1998cited by this paper
• The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.

  1998cited by this paper
• The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase.

  1997cited by this paper
• The γ134.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the α subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase

  1997cited by this paper
• Structure and function in the herpes simplex virus 1 RNA-binding protein U(s)11: mapping of the domain required for ribosomal and nucleolar association and RNA binding in vitro

  1996cited by this paper
• A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function.

  1996cited by this paper
• Herpes simplex virus VP16 rescues viral mRNA from destruction by the virion host shutoff function.

  1996cited by this paper
• Post-transcriptional transactivation of human retroviral envelope glycoprotein expression by herpes simplex virus Us11 protein

  1996influential reference
• Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herpes simplex virus 1.

  1995cited by this paper
• The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein.

  1993cited by this paper
• The US 9, 10, 11, and 12 genes of herpes simplex virus type 1 are of no importance for its neurovirulence and latency in mice.

  1993cited by this paper
• Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis

  1993cited by this paper
• The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60S subunits

  1992cited by this paper
• The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells.

  1992cited by this paper
• Herpes simplex virus 1 RNA-binding protein US11 negatively regulates the accumulation of a truncated viral mRNA

  1991influential reference
• The herpes simplex virus Us11 open reading frame encodes a sequence-specific RNA-binding protein

  1990influential reference
• Generation of an inverting herpes simplex virus 1 mutant lacking the L-S junction a sequences, an origin of DNA synthesis, and several genes including those specifying glycoprotein E and the alpha 47 gene

  1986cited by this paper
• The y134.5 gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

  year unknowninfluential reference

• Isolation, structural characterization, and antiviral activity of a sulfated polysaccharide (LJP-1) from Laminaria japonica.

  2025cites this paper
• Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

  2025cites this paper
• TDP-43 promotes efficient HSV-1 replication in human DRG-derived neurons

  2025cites this paper
• TDP-43 promotes efficient HSV-1 replication in human DRG-derived neurons

  2025cites this paper
• Import of extracellular 2'-3'cGAMP by the folate transporter, SLC19A1, establishes an antiviral response that limits Herpes Simplex Virus-1.

  2024cites this paper
• Suppression of HSV-1 infection and viral reactivation by CRISPR-Cas9 gene editing in 2D and 3D culture models

  2024cites this paper
• Herpes Simplex Virus-1 targets the 2’-3’cGAMP importer SLC19A1 as an antiviral countermeasure

  2024cites this paper
• A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

  2024cites this paper
• Herpes simplex virus-1 targets the 2'-3'cGAMP importer SLC19A1 as an antiviral countermeasure.

  2024cites this paper
• BiP/GRP78 is a pro-viral factor for diverse dsDNA viruses that promotes the survival and proliferation of cells upon KSHV infection

  2024cites this paper
• HSV-1 Infection Alters MAPT Splicing and Promotes Tau Pathology in Neural Models of Alzheimer’s Disease

  2024cites this paper
• BiP/GRP78 is a pro-viral factor for diverse dsDNA viruses that promotes the survival and proliferation of cells upon KSHV infection

  2023cites this paper
• Data mining reveals tissue-specific expression and host lineage-associated forms of Apis mellifera filamentous virus

  2023cites this paper
• Discovery of a Novel Intron in US10/US11/US12 of HSV-1 Strain 17

  2023cites this paper
• Comprehensive analysis of liquid–liquid phase separation propensities of HSV‐1 proteins and their interaction with host factors

  2023cites this paper
• Development of broadly neutralizing antibodies targeting the cytomegalovirus subdominant antigen gH

  2022cites this paper
• DLK-dependent biphasic reactivation of herpes simplex virus latency established in the absence of antivirals

  2022influential citation
• Recent insights into viral infections as a trigger and accelerator in alzheimer's disease

  2022influential citation
• An eIF3d-dependent switch regulates HCMV replication by remodeling the infected cell translation landscape to mimic chronic ER stress

  2022cites this paper
• DLK-Dependent Biphasic Reactivation of Herpes Simplex Virus Latency Established in the Absence of Antivirals

  2022influential citation
• Preventing translational inhibition from ribosomal protein insufficiency by a herpes simplex virus–encoded ribosome-associated protein

  2021cites this paper
• PML‐NB‐dependent type I interferon memory results in a restricted form of HSV latency

  2021influential citation
• TMEM41B is a pan-flavivirus host factor

  2020cites this paper
• E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes

  2020cites this paper
• “Non-Essential” Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review

  2020cites this paper
• Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

  2020influential citation
• TMEM41B Is a Pan-flavivirus Host Factor

  2020influential citation
• Inhibitory effects of baicalein against herpes simplex virus type 1

  2020cites this paper
• Subjugating Translational Inhibition in Response to Ribosomal Protein Insufficiency by a Herpesvirus Ribosome-Associated Protein

  2020cites this paper
• Neuronal hyperexcitability is a DLK-dependent trigger of HSV-1 reactivation that can be induced by IL-1

  2020cites this paper
• Herpes simplex virus type 1 and Alzheimer’s disease: link and potential impact on treatment

  2019cites this paper
• The Kinesin Light Chain–Related Protein PAT1 Promotes Superoxide Anion Production in Human Phagocytes

  2019cites this paper
• Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen

  2019cites this paper
• The US11 Gene of Herpes Simplex Virus 1 Promotes Neuroinvasion and Periocular Replication following Corneal Infection

  2019cites this paper
• TOP2β-Dependent Nuclear DNA Damage Shapes Extracellular Growth Factor Responses via Dynamic AKT Phosphorylation to Control Virus Latency.

  2019cites this paper
• Topoisomerase 2β-dependent nuclear DNA damage shapes extracellular growth factor responses through AKT phosphorylation dynamics to control virus latency

  2019cites this paper
• The regulatory factor ELF1 triggers a critical wave of transcription in the antiviral response to type I interferon

  2019cites this paper
• Protein interacting with Amyloid Precursor Protein tail-1 (PAT1) is involved in early endocytosis

  2019cites this paper
• Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off

  2019cites this paper
• Using Primary SCG Neuron Cultures to Study Molecular Determinants of HSV-1 Latency and Reactivation.

  2019cites this paper
• The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response

  2019cites this paper
• Microtubule-Dependent Trafficking of Alphaherpesviruses in the Nervous System: The Ins and Outs

  2019cites this paper
• Topoisomerase 2β-dependent nuclear DNA damage shapes extracellular growth factor responses via dynamic AKT phosphorylation to control virus latency

  2019cites this paper
• RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β

  2018cites this paper
• Proteomic profile associated with cell death induced by androgens in Taenia crassiceps cysticerci: proposed interactome

  2018cites this paper
• Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton

  2018cites this paper
• Restriction of γ34.5-Deleted Oncolytic Herpes Simplex Virus-1 in Glioblastoma Stem Cells and Therapies to Treat Them

  2018cites this paper
• Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors

  2017influential citation
• Shared ancestry of herpes simplex virus 1 strain Patton with recent clinical isolates from Asia and with strain KOS63.

  2017influential citation
• Investigations into the mechanisms involved in baculovirus nucleocapsid egress

  2017cites this paper
• Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons

  2017cites this paper
• Herpesvirus Late Gene Expression: A Viral-Specific Pre-initiation Complex Is Key

  2016cites this paper
• HSV-1 tegument protein and the development of its genome editing technology

  2016cites this paper
• ISG15 deficiency and increased viral resistance in humans but not mice

  2016cites this paper
• Comparative Study of Colon Cancer Subclones Uncovers Potential Roles for AKAP7 and TP53RK in the Antiviral Response.

  2016cites this paper
• Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11

  2015cites this paper
• Superior Versus Inferior Vestibular Neuritis: Are There Intrinsic Differences in Infection, Reactivation, or Production of Infectious Particles Between the Vestibular Ganglia?

  2015cites this paper
• PAT1 inversely regulates the surface Amyloid Precursor Protein level in mouse primary neurons

  2015cites this paper
• The Effects of Dexamethasone and Acyclovir on a Cell Culture Model of Delayed Facial Palsy

  2014cites this paper
• CytoskeletonInteractions with the Host

  2014cites this paper
• IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

  2014cites this paper
• PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System

  2014cites this paper
• Co-opting the Fanconi anemia genomic stability pathway enables herpesvirus DNA synthesis and productive growth.

  2014cites this paper
• Suppression of PACT-Induced Type I Interferon Production by Herpes Simplex Virus 1 Us11 Protein

  2013cites this paper
• Manipulation of Cellular Processing Bodies and Their Constituents by Viruses

  2013cites this paper
• Plus-end tracking proteins, CLASPs, and a viral Akt mimic regulate herpesvirus-induced stable microtubule formation and virus spread

  2013cites this paper
• Directional Spread of Alphaherpesviruses in the Nervous System

  2013cites this paper
• A Cell Culture Model of Facial Palsy Resulting From Reactivation of Latent Herpes Simplex Type 1

  2012cites this paper
• A primary neuron culture system for the study of herpes simplex virus latency and reactivation.

  2012cites this paper
• Axonal Sorting and Transport During Alphaherpesvirus Infection in Neurons

  2012cites this paper
• Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E

  2012cites this paper
• Coupling viruses to dynein and kinesin‐1

  2011cites this paper
• Regulation de la nadph oxydase phagocytaire par la pat1 « protein interacting with app tail 1

  2011cites this paper
• Nucleolin Interacts with US11 Protein of Herpes Simplex Virus 1 and Is Involved in Its Trafficking

  2011cites this paper
• Cultured vestibular ganglion neurons demonstrate latent HSV1 reactivation

  2011cites this paper
• RNA binding properties of the US11 protein from four primate simplexviruses

  2011cites this paper
• Alphaherpesviruses and the Cytoskeleton in Neuronal Infections

  2011cites this paper
• Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System

  2011cites this paper
• Étude de la sortie du virus herpès simplex de type 1 (HSV 1) hors du noyau

  2010cites this paper
• APP, APOE, complement receptor 1, clusterin and PICALM and their involvement in the herpes simplex life cycle.

  2010cites this paper
• Molecular anatomy of subcellular localization of HSV-1 tegument protein US11 in living cells

  2010cites this paper
• Nature and duration of growth factor signaling through receptor tyrosine kinases regulates HSV-1 latency in neurons.

  2010cites this paper
• Role of tegument proteins in herpesvirus assembly and egress

  2010cites this paper
• Plus- and Minus-End Directed Microtubule Motors Bind Simultaneously to Herpes Simplex Virus Capsids Using Different Inner Tegument Structures

  2010cites this paper
• Herpes simplex virus type 1 infection increases the carbohydrate binding activity and the secretion of cellular galectin-3

  2009cites this paper
• Requirement for microtubule integrity in the SOCS1‐mediated intracellular dynamics of HIV‐1 Gag

  2009cites this paper
• Functional roles of the tegument proteins of herpes simplex virus type 1.

  2009cites this paper
• Comparing the activities of US11, a herpes simplex virus protein that binds double-stranded RNA and inhibits PKR

  2008cites this paper
• Transport and egress of herpes simplex virus in neurons

  2008cites this paper
• Inflammation as a potential mediator for the association between periodontal disease and Alzheimer’s disease

  2008cites this paper
• Herpesvirus Interactions with the Host Cytoskeleton

  2008cites this paper
• Interactions between the products of the Herpes simplex genome and Alzheimer's disease susceptibility genes: relevance to pathological-signalling cascades.

  2008cites this paper
• Herpes simplex virus infection causes cellular beta-amyloid accumulation and secretase upregulation.

  2007cites this paper
• Three-Dimensional Structure of the Human Cytomegalovirus Cytoplasmic Virion Assembly Complex Includes a Reoriented Secretory Apparatus

  2007cites this paper
• Herpes simplex virus type 1, apolipoprotein E, and cholesterol: a dangerous liaison in Alzheimer's disease and other disorders.

  2006cites this paper
• Hepatitis B Virus X Protein Induces Perinuclear Mitochondrial Clustering in Microtubule- and Dynein-Dependent Manners

  2006cites this paper
• Reconstitution of Herpes Simplex Virus Microtubule-Dependent Trafficking In Vitro

  2006cites this paper
• Viral stop-and-go along microtubules: taking a ride with dynein and kinesins.

  2005cites this paper
• Herpes simplex virus type 2 membrane protein UL56 associates with the kinesin motor protein KIF1A.

  2005cites this paper
• HIV infection and AIDS Antigen presentation and the role of dendritic cells in HIV Related review: Antigenpresentation and the role of dendritic cells in HIV (pp 1–6)

  2004cites this paper