T follicular helper cell differentiation, function, and roles in disease.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Immunity

• Publication date

  2014-10-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.immuni.2014.10.004PMID 25367570PMCID PMC4223692
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• T Follicular Helper Cells

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• T follicular Helper Cells

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• Memory B cells contribute to rapid Bcl6 expression by memory follicular helper T cells

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• The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells

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• Faculty Opinions recommendation of Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development.

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• In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation.

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• Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells.

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• The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells

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• Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

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