A nomenclature consensus for nervous system organoids and assembloids

No abstract is available for this paper.

• Publication year

  2022

• Venue

  Nature

• Publication date

  2022-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/s41586-022-05219-6PMID 36171373PMCID PMC10571504
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human brain organogenesis: Toward a cellular understanding of development and disease.

  2021cited by this paper
• High-throughput single-cell transcriptomics on organoids.

  2019cited by this paper
• Assembling human brain organoids

  2019cited by this paper
• Transplantation of Human Brain Organoids: Revisiting the Science and Ethics of Brain Chimeras.

  2019cited by this paper
• Brain organoids: advances, applications and challenges

  2019cited by this paper
• The rise of three-dimensional human brain cultures

  2018cited by this paper
• The ethics of experimenting with human brain tissue

  2018cited by this paper
• The use of brain organoids to investigate neural development and disease

  2017cited by this paper
• Human induced pluripotent stem cells for modelling neurodevelopmental disorders

  2017cited by this paper
• The promises and challenges of human brain organoids as models of neuropsychiatric disease

  2016cited by this paper
• Organogenesis in a dish: Modeling development and disease using organoid technologies

  2014cited by this paper
• Cytosystems dynamics in self-organization of tissue architecture

  2013cited by this paper
• Advances, Applications, and Challenges

  2012cited by this paper
• Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals.

  2008cited by this paper

• Advances in three-dimensional modeling of ischemic injury

  2026cites this paper
• Permeability of the Blood–Brain Barrier (BBB) to Nanoparticles, Bacteria and Phages Studied in BBB Organoids Under Normoxic and Hypoxic Conditions In Vitro

  2026cites this paper
• Brain organoids in environmental neurotoxicology: applications, mechanisms, and future perspectives.

  2026cites this paper
• Guided and unguided neural organoids play complementary roles in studying neurodevelopment and neuroinflammation.

  2026cites this paper
• A Robust Methodological Framework for Generating Whole‐Brain and Cortical Organoids From Diverse Healthy‐ and Patient‐Derived Induced Pluripotent Stem Cell Lines

  2026cites this paper
• Developmental convergence and divergence in human stem cell models of autism.

  2026cites this paper
• A 3D multi-compartment assembloid to study combined immune cell infiltration and cytotoxicity.

  2026cites this paper
• Urgency with integrity: Why the profound autism community needs brain organoids now.

  2026cites this paper
• In silico screening and preclinical validation identify bavisant as a therapeutic candidate for multiple sclerosis.

  2026cites this paper
• Cell-Based Computational Models of Organoids: A Systematic Review

  2026cites this paper
• Neuromechanobiology: Bridging Mechanobiology and Neuroscience Through Evidence and Open Questions

  2026cites this paper
• Tumor immune organoids in immunotherapy resistance and drug screening.

  2026cites this paper
• Microglia-associated progression of multiple sclerosis: target identification and therapeutic engagement in human in vitro models.

  2026cites this paper
• Patient-derived complex organoids are a critical tool to understand and explore pediatric malignant brain tumors

  2026cites this paper
• Transparent multifunctional memristor based on amorphous InAlZnO for biomimetic sensing system

  2025cites this paper
• Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

  2025cites this paper
• Human Brain Organoids: Development and Applications

  2025cites this paper
• 3D Bioprinting Models for Glioblastoma: From Scaffold Design to Therapeutic Application

  2025cites this paper
• Modeling cerebral development in vitro with L-MYC-immortalized human neural stem cell-derived organoids

  2025cites this paper
• Modeling forebrain regional development and connectivity by human brain organoids.

  2025cites this paper
• Bioengineering tools for next-generation neural organoids.

  2025cites this paper
• Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy.

  2025cites this paper
• Advances in physiological and clinical relevance of hiPSC-derived brain models for precision medicine pipelines

  2025cites this paper
• Engineering organoids for dental pulp tissue regeneration and functional reconstruction.

  2025cites this paper
• Vascularised organoids: Recent advances and applications in cancer research

  2025cites this paper
• Exploring human brain development and disease using assembloids.

  2025cites this paper
• 3D cell culture models: how to obtain and characterize the main models

  2025cites this paper
• Application of new approach methodologies for nonclinical safety assessment of drug candidates

  2025cites this paper
• Breakthroughs and challenges of organoid models for assessing cancer immunotherapy: a cutting-edge tool for advancing personalised treatments

  2025cites this paper
• Brain organoid model systems of neurodegenerative diseases: recent progress and future prospects

  2025cites this paper
• Next-Gen Stroke Models: The Promise of Assembloids and Organ-on-a-Chip Systems

  2025cites this paper
• Roadmap for direct and indirect translation of optogenetics into discoveries and therapies for humans

  2025cites this paper
• Establishment and transcriptomic characterization of canine organoids from multiple tissues

  2025cites this paper
• Evolving from organoid to assembloid with enhanced cellular interactions

  2025cites this paper
• Microglia-containing neural organoids as brain microphysiological systems for long-term culture

  2025cites this paper
• Geometrically-engineered human motor assembloids-on-a-chip for neuromuscular interaction readout and hypoxia-driven disease modeling

  2025cites this paper
• Recent Advances in Microfluidics and Bioelectronics for Three-Dimensional Organoid Interfaces

  2025cites this paper
• Stem cell-derived neural organoids as platforms to investigate glioblastoma invasion and migration: A systematic review

  2025cites this paper
• Mechanical impact on neural stem cell lineage decisions in human brain organoids

  2025cites this paper
• Rebuilding the brain: a narrative review of glial transplantation in neurological diseases

  2025cites this paper
• Liminal Bioethics for Liminal Statuses: A New Method for Analysing Novel Biological Entities.

  2025cites this paper
• Dual developmental effects of ARX poly-alanine mutations on human cortical excitatory and inhibitory neurons.

  2025cites this paper
• Organoids and Organoids‐on‐Chip in Traditional Chinese Medicine Research: Applications, Advantages, and Future Prospects

  2025cites this paper
• Brain Organoids: Tools for Understanding the Uniqueness and Individual Variability of the Human Brain.

  2025cites this paper
• Skeletal interoception and prospective application in biomaterials for bone regeneration

  2025cites this paper
• Modelling sex differences of neurological disorders in vitro

  2025cites this paper
• Advances, challenges, and opportunities of human midbrain organoids for modelling of the dopaminergic system

  2025cites this paper
• Skeletal muscle, neuromuscular organoids and assembloids: a scoping review

  2025cites this paper
• Advances in Miniaturized Bioreactors: Bridging Biotechnology and Tissue Engineering for Enhanced Drug Development

  2025cites this paper
• Brain Organoids and Assembloids—From Disease Modeling to Drug Discovery

  2025cites this paper
• Untangling the Molecular Mechanisms Contributing to Autism Spectrum Disorder Using Stem Cells

  2025cites this paper
• Cell Type-Agnostic Transcriptomic Signatures Enable Uniform Comparisons of Neurodevelopment

  2025cites this paper
• Pathway-like Activation of 3D Neuronal Constructs with an Optical Interface

  2025cites this paper
• Ex Vivo Drug Screening: An Emerging Paradigm in the Treatment of Childhood Cancer.

  2025cites this paper
• Linking autism risk genes to morphological and pharmaceutical screening by high‐content imaging: Future directions and opinion

  2025cites this paper
• Brain organoids: building higher-order complexity and neural circuitry models

  2025cites this paper
• From Organoids to Assembloids: Experimental Approaches to Study Human Neuropsychiatric Disorders.

  2025cites this paper
• Thalamic NRXN1-Mediated Input to Human Cortical Progenitors Drives Upper Layer Neurogenesis

  2025cites this paper
• Functional Neurogenomics to Dissect Disease Mechanisms Across Models.

  2025cites this paper
• Assessing the Utility of Organoid Intelligence: Scientific and Ethical Perspectives

  2025cites this paper
• Recent Advances in Three-Dimensional In Vitro Models for Studies of Liver Fibrosis

  2025cites this paper
• Neuromuscular and cardiac organoids and assembloids: Advanced platforms for drug testing.

  2025cites this paper
• Artificial Intelligence for Organoids Multidimensional Assessment

  2025cites this paper
• Using cortical organoids to understand the pathogenesis of malformations of cortical development

  2025cites this paper
• Molecular hallmarks of hydrocephalus.

  2025cites this paper
• Development of a network formation assay for developmental neurotoxicity hazard screening using 3D human iPSC derived BrainSpheres

  2025cites this paper
• The role of endothelial-derived factors in neural tube development: implications for organoid models

  2025cites this paper
• The Evolving Landscape of Functional Models of Autism Spectrum Disorder

  2025cites this paper
• Scalable production of human cortical organoids using a biocompatible polymer

  2025cites this paper
• Nearness by design: modeling brains with organoids

  2025cites this paper
• Building Immunocompetent Cerebral Organoids From a Developmental Perspective

  2025cites this paper
• Mutations in GFAP Alter Early Lineage Commitment of Organoids

  2025cites this paper
• Towards a quality control framework for cerebral cortical organoids

  2025cites this paper
• Innovative strategies for bone organoid: Synergistic application and exploration of advanced technologies

  2025cites this paper
• Human cerebral organoids model tumor initiation and infiltration in an autologous astrocyte-supported setting

  2025cites this paper
• Human myelinated brain organoids with integrated microglia as a model for myelin repair and remyelinating therapies.

  2025cites this paper
• Facing the possibility of consciousness in human brain organoids

  2025cites this paper
• Human Stem Cell-Based Embryo Model Research: Ethics and Regulations.

  2025cites this paper
• Functional recovery through the plastic adaptation of organoid grafts in cortical tissue

  2025cites this paper
• Modelling the human brain in vitro: biofabrication approaches for neural tissue engineering

  2025influential citation
• Unraveling the complexity of cognitive impairment following high-altitude exposure: from preclinical animal models to human organoids

  2025cites this paper
• Single rosette-based generation of uniform cortical assembloids recapitulating cellular interactions between neurons and glial cells

  2025cites this paper
• Current Position and Future Direction of Inflammation in Neuropsychiatric Disorders: A Review.

  2025cites this paper
• Cerebral organoids expressing mutant actin genes reveal cellular mechanism underlying microcephaly

  2025cites this paper
• The need for a global effort to attend to human neural organoid and assembloid research.

  2025cites this paper
• In vitro reconstitution of hippocampal cell assemblies

  2025cites this paper
• Organoid Ethical Typology: varieties of three‐dimensional stem cell constructs and the many issues they raise in bioethics

  2025cites this paper
• Host circuit engagement of human cortical organoids transplanted in rodents

  2024cites this paper
• Recent Advances in the Treatment of Spinal Cord Injury

  2024cites this paper
• Collaborative ethics: innovating collaboration between ethicists and life scientists

  2024cites this paper
• Pluripotent stem cell‐derived organoids: A brief history of curiosity‐led discoveries

  2024cites this paper
• Comparison of primary and passaged tumor cell cultures and their application in personalized medicine

  2024cites this paper
• Bone-organ axes: bidirectional crosstalk

  2024cites this paper
• Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differences

  2024cites this paper
• Recent advances in cell-based in vitro models for predicting drug permeability across brain, intestinal, and pulmonary barriers

  2024cites this paper
• Using Organoids to Model Sex Differences in the Human Brain

  2024cites this paper
• Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application.

  2024cites this paper
• Gnao1 is a molecular switch that regulates the Rho signaling pathway in differentiating neurons

  2024cites this paper
• Establishing Neural Organoid Cultures for Investigating the Effects of Microgravity in Low-Earth Orbit (LEO).

  2024cites this paper
• A Standardized Nomenclature Design for Systematic Referencing and Identification of Animal Cellular Material

  2024cites this paper