Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Chemico-Biological Interactions

• Publication date

  2008-01-10

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/J.CBI.2007.09.005PMID 17950719
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Methods of Enzymatic Analysis

  2019cited by this paper
• Spinal mechanisms of antinociceptive action caused by diphenyl diselenide.

  2007cited by this paper
• Low cadmium exposure triggers a biphasic oxidative stress response in mice kidneys.

  2007cited by this paper
• Cadmium induced mitochondrial injury and apoptosis in vero cells: protective effect of diallyl tetrasufide from garlic.

  2007cited by this paper
• Acute liver damage induced by 2-nitropropane in rats: effect of diphenyl diselenide on antioxidant defenses.

  2006cited by this paper
• Antisecretory and antiulcer effects of diphenyl diselenide.

  2006cited by this paper
• Oral exposure to cadmium chloride triggers an acute inflammatory response in the intestines of mice, initiated by the over-expression of tissue macrophage inflammatory protein-2 mRNA.

  2006cited by this paper
• Role of trace elements in cadmium chloride uptake in hepatoma cell lines.

  2006cited by this paper
• Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress.

  2006cited by this paper
• Protective effect of diphenyl diselenide on acute liver damage induced by 2-nitropropane in rats.

  2005cited by this paper
• Diphenyl diselenide reverses cadmium-induced oxidative damage on mice tissues.

  2005cited by this paper
• Efficacy of 2,3-dimercapto-1-propanesulfonic acid (DMPS) and diphenyl diselenide on cadmium induced testicular damage in mice.

  2005cited by this paper
• Cadmium induced testicular damage and its response to administration of succimer and diphenyl diselenide in mice.

  2004cited by this paper
• Protective role of aryl and alkyl diselenides on lipid peroxidation.

  2004cited by this paper
• Cadmium inhibits the electron transfer chain and induces reactive oxygen species.

  2004cited by this paper
• Organoselenium and organotellurium compounds: toxicology and pharmacology.

  2004cited by this paper
• Expression of adhesion molecules during cadmium hepatotoxicity.

  2004cited by this paper
• Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and beta-carotene.

  2004cited by this paper
• Involvement of calcium channels in the sexual dimorphism of cadmium-induced hepatotoxicity.

  2003cited by this paper
• Anti-inflammatory and antinociceptive activity of diphenyl diselenide

  2003cited by this paper
• A global perspective on cadmium pollution and toxicity in non-occupationally exposed population.

  2003cited by this paper
• Differential hepatotoxicity induced by cadmium in Fischer 344 and Sprague-Dawley rats.

  2002cited by this paper
• Molecular inhibitory mechanisms of antioxidant enzymes in rat liver and kidney by cadmium.

  2002cited by this paper
• Handbook of Toxicology

  2001cited by this paper
• Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice.

  2001cited by this paper
• Lysosomal membrane stability and metallothioneins in digestive gland of Mussels (Mytilus galloprovincialis Lam.) as biomarkers in a field study.

  2001cited by this paper
• Mechanisms of cadmium‐mediated acute hepatotoxicity

  2000cited by this paper
• Attenuation of cadmium-induced liver injury in senescent male fischer 344 rats: role of Kupffer cells and inflammatory cytokines.

  2000cited by this paper
• Binding of tellurium to hepatocellular selenoproteins during incubation with inorganic tellurite: consequences for the activity of selenium-dependent glutathione peroxidase.

  1999cited by this paper
• Treatment of chronic cadmium nephrotoxicity by N-acetyl cysteine.

  1999cited by this paper
• Influence of glycine on the damage induced in isolated perfused rat liver by five hepatotoxic agents.

  1998cited by this paper
• Cadmium‐induced renal dysfunction: New mechanism, treatment and prevention

  1998cited by this paper
• A simple spectrophotometric method for metallothionein evaluation in marine organisms: an application to Mediterranean and Antarctic molluscs

  1997cited by this paper
• 15 – Renal Effects of Metals

  1995cited by this paper
• Toxicology of cadmium

  1995cited by this paper
• Inhibition of Na(+)-glucose cotransport in kidney cortical cells by cadmium and copper: protection by zinc.

  1994cited by this paper
• Effect of cadmium on some enzyme activities in first-trimester human placentae.

  1992cited by this paper
• Zn(II), Cd(II) and Cu(II) interactions on glutathione reductase and glucose-6-phosphate dehydrogenase.

  1989cited by this paper
• Interaction of cadmium with brush border membrane vesicles from the rat small intestine.

  1989cited by this paper
• In vitro effects of cadmium and arsenite on glutathione peroxidase, aspartate and alanine aminotransferases, cholinesterase and glucose-6-phosphate dehydrogenase activities in blood.

  1989cited by this paper
• Selenium Reagents and Intermediates in Organic Synthesis

  1986cited by this paper
• Organic hydroperoxide-induced lipid peroxidation and cell death in isolated hepatocytes.

  1985cited by this paper
• Catalase in vitro.

  1984cited by this paper
• International Federation of Clinical Chemistry, (IFCC), Scientific Committee, Analytical Section. IFCC methods for the measurement of catalytic concentration of enzymes. Part 4. IFCC method for gamma-glutamyltransferase [(gamma-glutamyl)-peptide: amino acid gamma-glutamyltransferase, EC 2.3.2.2].

  1983cited by this paper
• Delta-aminolevulinic acid dehydratase assay.

  1982cited by this paper
• Acute exposure to cadmium causes severe liver injury in rats.

  1982cited by this paper
• Cadmium toxicity and lipid peroxidation in isolated rat hepatocytes.

  1980cited by this paper
• Nature of materials in serum that interfere in the glucose oxidase-peroxidase-0-dianisidine method for glucose, and their mode of action.

  1975cited by this paper
• Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

  1974cited by this paper
• The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase.

  1972cited by this paper
• A method for the colorimetric estimation of glycogen with iodine.

  1962cited by this paper
• Tissue sulfhydryl groups.

  1959cited by this paper
• A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.

  1957cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper
• THE DETERMINATION OF BILIRUBIN WITH THE PHOTOELECTRIC COLORIMETER

  1937cited by this paper
• THE CONCENTRATION OF UREA IN THE BLOOD OF NORMAL INDIVIDUALS.

  1927cited by this paper

• Diphenyl diselenide promotes antioxidant activity and reduces apoptosis, offering hepatorenal protection in Wistar rats exposed to diethyl nitrosamine.

  2025cites this paper
• Oral Administration of Cadmium Chloride Induces Oxidative Stress, DNA Damage and Histopathological Changes in Rat Intestine: A Dose‐Dependent Study

  2025cites this paper
• PROTECTIVE MODULATORY POTENTIAL OF AZOLLA PINNATA EXTRACT ON LIPID METABOLISM, HEPATIC DYSFUNCTIONING, ALONG WITH MITIGATION OF OXIDATIVE STRESS IN TRITON X-100 INDUCED HYPERLIPIDEMIC RATS

  2025cites this paper
• Evaluation of cadmium effects on the glucose metabolism on insulin resistance HepG2 cells

  2024cites this paper
• Assessment of toxic interaction of lead and chromium metals in binary mixture in quails: A hematological study

  2024cites this paper
• Oxidative stress-induced by different stressors alters kidney tissue antioxidant markers and levels of creatinine and urea: the fate of renal membrane integrity

  2023cites this paper
• Assessment of Oxidative Stress Indices in Tissues of Cadmium-challenged Female Wistar Rats Treated with Combined Ethanolic Leaf Extract of Manihot esculenta and Citrus sinensis

  2022cites this paper
• Bioactive phytochemicals from Salvia officinalis attenuate cadmium-induced oxidative damage and genotoxicity in rats

  2021cites this paper
• Lead nitrate and cadmium chloride induced hepatotoxicity and nephrotoxicity: Protective effects of sesamol on biochemical indices and pathological changes.

  2021cites this paper
• Toxicology and pharmacology of synthetic organoselenium compounds: an update

  2021cites this paper
• Cadmium Toxicity on Chondrocytes and the Palliative Effects of 1α, 25-Dihydroxy Vitamin D3 in White Leghorns Chicken's Embryo

  2021cites this paper
• Continuous-flow electrosynthesis of selenium-substituted iminoisobenzofuran via oxidative cyclization of olefinic amides and diselenides.

  2021cites this paper
• Comparison of Protective Effect of Apium graveolens and Aloe vera Supplemented with Zinc on Cadmium Induced Hepato and Nephro-Toxicity in Wistar Rats

  2021cites this paper
• Similar hepatoprotective effectiveness of diphenyl diselenide and Ebselen against cisplatin-induced disruption of metabolic homeostasis and redox balance in juvenile rats.

  2020cites this paper
• Effect of feeding strategy of probiotic Enterococcus faecium on growth performance, hematologic, biochemical parameters and non-specific immune response of Nile tilapia

  2020cites this paper
• Oxidative stress, DNA damage and apoptosis induced by tebuconazole in kidney of male Wistar rats.

  2020cites this paper
• Protective Effect of Grape and Apple Juices against Cadmium Intoxication in the Kidney of Rats

  2020cites this paper
• Diphenyl diselenide is as effective as Ebselen in a juvenile rat model of cisplatin-induced nephrotoxicity.

  2020cites this paper
• POSSIBLE PROTECTIVE EFFECT OF CARNOSINE ON CADMIUM-INDUCED RENAL DYSFUNCTION IN OLD RATS

  2019cites this paper
• Organodiselenides: Organic Catalysis and Drug Design Learning from Glutathione Peroxidase

  2019cites this paper
• Long-term effect of diet amended by risk elements contaminated soils on risk element penetration and physiological parameters of rats

  2018cites this paper
• The impacts of Elaeagnus umbellata Thunb. leaf and fruit aqueous extracts on mice hepatic, extrahepatic antioxidant and drug metabolizing enzymes related structures

  2018influential citation
• Hepatotoxicity of Copper, Iron, Cadmium, and Arsenic

  2018cites this paper
• Are Grapes Able to Mitigate the Noxious Effects Induced by Cadmium Exposure in Different Tissues and/or Organs? A Mini Review

  2018cites this paper
• Protective effects of polydatin and grape seed extract in rats exposed to cadmium

  2018cites this paper
• Investigation into the intracellular fates, speciation and mode of action of selenium-containing neuroprotective agents using XAS and XFM.

  2018cites this paper
• Protective effect of methanolic Peel extract of Punica granatum on cadmium- induced hepatotoxicity in mice: Histological and ultrastructural investigation

  2017cites this paper
• Curcumin attenuates memory deficits and the impairment of cholinergic and purinergic signaling in rats chronically exposed to cadmium

  2017influential citation
• Metabolomic analysis for combined hepatotoxicity of chlorpyrifos and cadmium in rats.

  2017cites this paper
• Copper‐Iodide‐ and Diorganyl‐Diselenide‐Promoted Cyclization of 2‐Alkynylphenols: Alternative Approach to 3‐Organoselanylbenzo[b]furans

  2017cites this paper
• Pre and Post-Treatment Effects: Estimation of Serum Testosterone and Lipid Peroxidation Levels on Moringa olifera Extract Induced Cadmium Exposed Rats

  2017cites this paper
• Biochemical and histopathological changes of subacute cadmium intoxication in male rats

  2017cites this paper
• Antioxidant compound (E)-2-benzylidene-4-phenyl-1,3-diselenole protects rats against thioacetamide-induced acute hepatotoxicity.

  2017cites this paper
• Effect of high fructose administration on histopathology of kidney, heart and aorta of rats

  2017cites this paper
• Effect of Lead Intoxication and Fresh Camel Milk Treatment on Kidney Functions Indices in Albino Rats

  2017cites this paper
• Are food compounds able to modulate noxious activities induced by cadmium exposure?

  2017cites this paper
• Effect of Selenium Supplementation on Serum Amylase, Lactate Dehydrogenase and Alkaline Phosphatase Activities in Rats Exposed to Cadmium or Lead

  2015cites this paper
• Oxidative stress, biochemical alterations, and hyperlipidemia in female rats induced by lead chronic toxicity during puberty and post puberty periods

  2015cites this paper
• Histopathological evidences for effect beneficial of Satureja hortensis extract on hepatic lesion by cadmium–induced in Rat

  2015cites this paper
• Apple juice attenuates genotoxicity and oxidative stress induced by cadmium exposure in multiple organs of rats.

  2015cites this paper
• Diphenyl diselenide protects against metabolic disorders induced by acephate acute exposure in rats

  2014cites this paper
• Positive effects of Green Tea ( Camellia Sinensis ) on Hepatic Dysfunction induced by lead Acetate in Male Rat

  2014cites this paper
• Protective effects of blueberries (Vaccinium corymbosum L.) extract against cadmium-induced hepatotoxicity in mice.

  2014cites this paper
• Hepatoprotective Effect of Arctium lappa Root Extract on Cadmium Toxicity in Adult Wistar Rats

  2014cites this paper
• Antimutagenic and antigenotoxic potential of grape juice concentrate in blood and liver of rats exposed to cadmium

  2014cites this paper
• Protective Effects of Alpha-lipoic Acid and Melatonin Against Cadmium-induced Oxidative Stress in Erythrocytes of Rats

  2014cites this paper
• Positive effects of Green Tea ( Camellia Sinensis ) on Hepatic Dysfunction induced by lead Acetate in Male Rat www . ijddr . in

  2014cites this paper
• Regulation effect of polysaccharides from Pleurotus tuber-regium (Fr.) on the immune activity of mice macrophages.

  2014cites this paper
• Seleno- and telluro-xylofuranosides attenuate Mn-induced toxicity in C. elegans via the DAF-16/FOXO pathway.

  2014cites this paper
• On the effect of chelating agents and antioxidants on cadmium-induced organ toxicity. An overview

  2013cites this paper
• Effectiveness of Maifanite in Reducing the Detrimental Effects of Cadmium on Growth Performance, Cadmium Residue, Hematological Parameters, Serum Biochemistry, and the Activities of Antioxidant Enzymes in Pigs

  2013cites this paper
• Histopathological evidences for effect beneficial of walnut extract on hepatic lesion by cadmium-induced in Rat

  2013cites this paper
• Effects of diphenyl diselenide and diphenyl ditellurite on chicken embryo development

  2013cites this paper
• NTPDase and 5′‐nucleotidase activities from synaptosomes and platelets of rats exposed to cadmium and treated with N‐acetylcysteine

  2013cites this paper
• Fenugreek seeds, a hepatoprotector forage crop against chronic AlCl3 toxicity

  2013cites this paper
• Histopathology and cytotoxicity as biomarkers in treated rats with cadmium and some therapeutic agents.

  2013cites this paper
• Poly (lactide-co-glycolide) nano-encapsulation of chelidonine, an active bioingredient of greater celandine (Chelidonium majus), enhances its ameliorative potential against cadmium induced oxidative stress and hepatic injury in mice.

  2013cites this paper
• Diphenyl diselenide prevents hepatic alterations induced by paraquat in rats.

  2013cites this paper
• Quercetin potentially attenuates cadmium induced oxidative stress mediated cardiotoxicity and dyslipidemia in rats.

  2013cites this paper
• Fenugreek seeds reduce aluminum toxicity associated with renal failure in rats

  2013cites this paper
• Protective effect of ascorbic acid after single and repetitive administration of cadmium in Swiss mice

  2012cites this paper
• Hematological indices and activity of NTPDase and cholinesterase enzymes in rats exposed to cadmium and treated with N-acetylcysteine

  2012cites this paper
• Route-dependent effects of cadmium/cadmium and magnesium acute treatment on parameters of oxidative stress in rat liver.

  2012cites this paper
• Protective effect of caffeic acid phenethyl ester against cadmium-induced renal damage in mice.

  2012cites this paper
• UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL INSTITUTO DE CIÊNCIAS BÁSICAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS BIOLÓGICAS: BIOQUÍMICA AVALIAÇÃO DE RESPOSTAS BIOQUÍMICAS, COMPORTAMENTAIS, HEMATOLÓGICAS E DE BIOACUMULAÇÃO EM RATOS EXPOSTOS AO CÁDMIO E TRATADOS COM N-ACETILCISTEÍNA

  2012cites this paper
• Diphenyl diselenide attenuates hepatic and hematologic toxicity induced by chlorpyrifos acute exposure in rats

  2012cites this paper
• Quercetin protects against cadmium-induced biochemical and structural changes in rat liver revealed by FT-IR spectroscopy

  2012cites this paper
• Effects of oral and intraperitoneal magnesium treatment against cadmium-induced oxidative stress in plasma of rats

  2012cites this paper
• Protective effects of ascorbic acid and zinc against cadmium-induced histopathological, histochemical and cytogenetic changes in rats

  2012cites this paper
• The effects of some boron compounds against heavy metal toxicity in human blood.

  2012cites this paper
• Ebselen reduces hyperglycemia temporarily-induced by diazinon: a compound with insulin-mimetic properties.

  2012cites this paper
• Involvement of catalase in the protective effect of binaphthyl diselenide against renal damage induced by glycerol.

  2011cites this paper
• Effect of Chronic Oral Administration of Chloroquine on the Histology of the Liver in Wistar Rats

  2011cites this paper
• Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds

  2011cites this paper
• Effect of Selenium Pre-treatment on Antioxidative Enzymes and Lipid Peroxidation in Cd-exposed Suckling Rats

  2011cites this paper
• Bradykinin potentiating factor isolated from Buthus occitanus venom has a protective effect against cadmium-induced rat liver and kidney damage.

  2011cites this paper
• Effect of age‐dependent exposure to lead on hepatotoxicity and nephrotoxicity in male rats

  2011cites this paper
• (E)‐2‐benzylidene‐4‐phenyl‐1,3‐diselenole has antioxidant and hepatoprotective properties against oxidative damage induced by 2‐nitropropane in rats

  2011cites this paper
• Effect of wheat bran and flaxseed on cadmium effects and retention in rats

  2011cites this paper
• Protective Effect of Methanolic Extract of Caesalpinia Bonduc (L.) on ArtesunateInduced Hepatotoxicity in Rats

  2010cites this paper
• Diphenyl diselenide in its selenol form has dehydroascorbate reductase and glutathione S‐transferase‐like activity dependent on the glutathione content

  2010cites this paper
• A comparative study on the biochemical effect of ocular and oral cadmium administration in rabbits

  2010cites this paper
• Alteration in the activity of oxidative enzymes in the tissues of male Wistar albino rats exposed to cadmium.

  2010cites this paper
• Environmental contaminants and human health in the Canadian Arctic.

  2010cites this paper
• 9.23 – Hepatotoxicity of Copper, Iron, Cadmium, and Arsenic

  2010cites this paper
• Amelioration of cadmium-induced oxidative stress, impairment in lipids and plasma lipoproteins by the combined treatment with quercetin and α-tocopherol in rats.

  2010cites this paper
• Association between diphenyl diselenide and cadmium chloride attenuates the toxicity of both in tissues of mice in vitro.

  2010cites this paper
• Glycine reduces cadmium-induced alterations in the viability and activation of macrophage U937 cells.

  2010cites this paper
• Comparative effect of water and food-chain mediated cadmium exposure in rats

  2010cites this paper
• Cadmium and Selenium Interaction in Mammals

  2010influential citation
• N-acetylcysteine prevents memory deficits, the decrease in acetylcholinesterase activity and oxidative stress in rats exposed to cadmium.

  2010cites this paper
• Involvement of selenoprotein P and GPx4 gene expression in cadmium-induced testicular pathophysiology in rat.

  2010cites this paper
• EFFECT OF CHRONIC ORAL ADMINISTRATION OF CHLOROQUINE ON THE WEIGHT OF THE HEART IN WISTAR RATS

  2010cites this paper
• Evidence against a direct role for oxidative stress in cadmium-induced axial malformation in the chick embryo.

  2010cites this paper
• Histological Effects of Oral Administration of Artesunate on the Liver in Wistar Rats

  2010cites this paper
• EFEITO HEPATOPROTETOR CAUSADO PELO 3-ALQUINIL SELENOFENO CONTRA O DANO OXIDATIVO INDUZIDO POR AGENTES QUÍMICOS EM RATOS

  2009cites this paper
• Selection and Identification of Differential Proteins of Liver Revealed with Proteomics in Achatina Fulica Under Induction of Cadmium

  2009cites this paper
• Influência de produtos alimentícios ricos em fibra na biodisponibilidade de cádmio e de metais essenciais

  2009cites this paper
• Involvement of non-enzymatic antioxidant defenses in the protective effect of diphenyl diselenide on testicular damage induced by cadmium in mice.

  2009cites this paper
• Enhanced zinc consumption prevents cadmium-induced alterations in lipid metabolism in male rats.

  2009cites this paper