Rodent Models of Spinal Cord Injury: From Pathology to Application

No abstract is available for this paper.

• Publication year

  2022

• Venue

  Neurochemical Research

• Publication date

  2022-10-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s11064-022-03794-8PMID 36303082
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• VX-765 reduces neuroinflammation after spinal cord injury in mice

  2021cited by this paper
• Sonic Hedgehog modulates the inflammatory response and improves functional recovery after spinal cord injury in a thoracic contusion–compression model

  2021cited by this paper
• HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats

  2021cited by this paper
• The thrombin receptor modulates astroglia‐neuron trophic coupling and neural repair after spinal cord injury

  2021cited by this paper
• Long-Term Effects of Neural Precursor Cell Transplantation on Secondary Injury Processes and Functional Recovery after Severe Cervical Contusion-Compression Spinal Cord Injury

  2021cited by this paper
• Extracellular vesicles derived from melatonin‐preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2

  2021cited by this paper
• Effect of electroacupuncture on inhibition of inflammatory response and oxidative stress through activating ApoE and Nrf2 in a mouse model of spinal cord injury

  2021cited by this paper
• Gsx1 promotes locomotor functional recovery after spinal cord injury

  2021cited by this paper
• Rapamycin Preserves Neural Tissue, Promotes Schwann Cell Myelination and Reduces Glial Scar Formation After Hemi-Contusion Spinal Cord Injury in Mice

  2021cited by this paper
• USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1

  2021cited by this paper
• Spinal cord injury inhibits the differentiation and maturation of NG2 cells in the cerebellum in mice.

  2021cited by this paper
• Highly Permeable DNA Supramolecular Hydrogel Promotes Neurogenesis and Functional Recovery after Completely Transected Spinal Cord Injury

  2021cited by this paper
• Effects of aerobic exercise training on muscle plasticity in a mouse model of cervical spinal cord injury

  2021cited by this paper
• Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury.

  2021cited by this paper
• miR‐378‐3p alleviates contusion spinal cord injury by negatively regulating ATG12

  2021cited by this paper
• Anatomical and Behavioral Outcomes following a Graded Hemi-contusive Cervical Spinal Cord Injury Model in Mice.

  2021cited by this paper
• Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury

  2021cited by this paper
• Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model

  2021cited by this paper
• Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis

  2021cited by this paper
• Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia.

  2021cited by this paper
• Effect of fecal microbiota transplantation on neurological restoration in a spinal cord injury mouse model: involvement of brain-gut axis

  2020cited by this paper
• Astrocytic YAP Promotes the Formation of Glia Scars and Neural Regeneration after Spinal Cord Injury

  2020cited by this paper
• TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress

  2020cited by this paper
• Alternate thermal stimulation ameliorates thermal sensitivity and modulates calbindin‐D 28K expression in lamina I and II and dorsal root ganglia in a mouse spinal cord contusion injury model

  2020cited by this paper
• Small molecules combined with collagen hydrogel direct neurogenesis and migration of neural stem cells after spinal cord injury.

  2020cited by this paper
• Induction of Complete Transection-Type Spinal Cord Injury in Mice.

  2020cited by this paper
• MiRNA-411 attenuates inflammatory damage and apoptosis following spinal cord injury.

  2020cited by this paper
• The Effects of a Ketogenic Diet on Sensorimotor Function in a Thoracolumbar Mouse Spinal Cord Injury Model

  2020cited by this paper
• Exogenous activation of cannabinoid-2 receptor modulates TLR4/MMP9 expression in a spinal cord ischemia reperfusion rat model

  2020cited by this paper
• NIMA-related kinase 7 amplifies NLRP3 inflammasome pro-inflammatory signaling in microglia/macrophages and mice models of spinal cord injury.

  2020cited by this paper
• Facial grimace testing as an assay of neuropathic pain-related behavior in a mouse model of cervical spinal cord injury.

  2020cited by this paper
• LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3

  2020cited by this paper
• The effects of mouse strain and age on a model of unilateral cervical contusion spinal cord injury

  2020cited by this paper
• Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function.

  2020cited by this paper
• Permanent diaphragmatic deficits and spontaneous respiratory plasticity in a mouse model of incomplete cervical spinal cord injury.

  2020cited by this paper
• Ezetimibe protects against spinal cord injury by regulating autophagy and apoptosis through inactivation of PI3K/AKT/mTOR signaling.

  2020cited by this paper
• Effect of Velocity and Duration of Residual Compression in a Rat Dislocation Spinal Cord Injury Model

  2020cited by this paper
• FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model

  2020cited by this paper
• Perforin affects regeneration in a mouse spinal cord injury model

  2020cited by this paper
• The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury

  2020cited by this paper
• Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury

  2020cited by this paper
• Combined Treatment with Fasudil and Menthol Improves Functional Recovery in Rat Spinal Cord Injury Model

  2020cited by this paper
• Congenital exercise ability ameliorates muscle atrophy but not spinal cord recovery in spinal cord injury mouse model

  2019cited by this paper
• Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling

  2019cited by this paper
• Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination

  2019cited by this paper
• Scaffold-facilitated locomotor improvement post complete spinal cord injury: Motor axon regeneration versus endogenous neuronal relay formation.

  2019cited by this paper
• Targeting CARD6 attenuates spinal cord injury (SCI) in mice through inhibiting apoptosis, inflammation and oxidative stress associated ROS production

  2019cited by this paper
• Curcumin promotes functional recovery and inhibits neuronal apoptosis after spinal cord injury through the modulation of autophagy

  2019cited by this paper
• SRμCT Reveals 3D Microstructural Alterations of the Vascular and Neuronal Network in a Rat Model of Chronic Compressive Thoracic Spinal Cord Injury

  2019cited by this paper
• Innovative mouse model mimicking human-like features of spinal cord injury: efficacy of Docosahexaenoic acid on acute and chronic phases

  2019cited by this paper
• Silencing miR‐21 induces polarization of astrocytes to the A2 phenotype and improves the formation of synapses by targeting glypican 6 via the signal transducer and activator of transcription‐3 pathway after acute ischemic spinal cord injury

  2019cited by this paper
• TGN‐020 alleviates edema and inhibits astrocyte activation and glial scar formation after spinal cord compression injury in rats

  2019cited by this paper
• Spinal cord injury by clip-compression induces anxiety and depression-like behaviours in female rats: The role of the inflammatory response.

  2019cited by this paper
• Functional Local Proprioceptive Feedback Circuits Initiate and Maintain Locomotor Recovery after Spinal Cord Injury.

  2019cited by this paper
• H-reflex disinhibition by lumbar muscle inflammation in a mouse model of spinal cord injury.

  2019cited by this paper
• Melatonin Treatment Alleviates Spinal Cord Injury-Induced Gut Dysbiosis in Mice

  2019cited by this paper
• Intravenous transplantation of olfactory bulb ensheathing cells for a spinal cord hemisection injury rat model

  2019cited by this paper
• Human gingival mesenchymal stem cells pretreated with vesicular moringin nanostructures as a new therapeutic approach in a mouse model of spinal cord injury

  2019cited by this paper
• Basic biomechanics of spinal cord injury — How injuries happen in people and how animal models have informed our understanding

  2019cited by this paper
• Reactivity of microglia and astrocytes after an excitotoxic injury induced by kainic acid in the rat spinal cord.

  2019cited by this paper
• A Laser-Guided Spinal Cord Displacement Injury in Adult Mice

  2018cited by this paper
• Graded photochemical spinal cord injury results in chronic hyperalgesia and depression-like behaviour but no anxiety exacerbation in female BALB/c mice.

  2018cited by this paper
• The attenuation of neurological injury from the use of simvastatin after spinal cord ischemia-reperfusion injury in rats

  2018cited by this paper
• Transient activation of Wnt/β-catenin signaling reporter in fibrotic scar formation after compression spinal cord injury in adult mice.

  2018cited by this paper
• Feasibility study on mouse live imaging after spinal cord injury and poly(lactide-co-glycolide) bridge implantation

  2018cited by this paper
• Locomotor recovery following contusive spinal cord injury does not require oligodendrocyte remyelination

  2018cited by this paper
• Time course of diffusion tensor imaging metrics in the chronic spinal cord compression rat model

  2018cited by this paper
• Schwann Cell Transplantation Subdues the Pro-Inflammatory Innate Immune Cell Response after Spinal Cord Injury

  2018cited by this paper
• Transplantation of rat-derived microglial cells promotes functional recovery in a rat model of spinal cord injury

  2018cited by this paper
• The prevention of delirium in elderly with obstructive sleep apnea (PODESA) study: protocol for a multi-centre prospective randomized, controlled trial

  2018cited by this paper
• The Biology of Regeneration Failure and Success After Spinal Cord Injury.

  2018cited by this paper
• Recent update on basic mechanisms of spinal cord injury

  2018cited by this paper
• Acrolein Contributes to the Neuropathic Pain and Neuron Damage after Ischemic-Reperfusion Spinal Cord Injury.

  2018cited by this paper
• Blood Glutamate Scavenger as a Novel Neuroprotective Treatment in Spinal Cord Injury

  2018cited by this paper
• Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury

  2018cited by this paper
• Safety and Efficacy of Rose Bengal Derivatives for Glial Scar Ablation in Chronic Spinal Cord Injury

  2018cited by this paper
• Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.

  2018cited by this paper
• Effect of combined chondroitinase ABC and hyperbaric oxygen therapy in a rat model of spinal cord injury

  2018influential reference
• Prophylactic Riluzole Attenuates Oxidative Stress Damage in Spinal Cord Distraction

  2018cited by this paper
• Level-Specific Differences in Systemic Expression of Pro- and Anti-Inflammatory Cytokines and Chemokines after Spinal Cord Injury

  2018cited by this paper
• Lentivirus-mediated silencing of the CTGF gene suppresses the formation of glial scar tissue in a rat model of spinal cord injury.

  2018cited by this paper
• Repeatability of a Dislocation Spinal Cord Injury Model in a Rat-A High-Speed Biomechanical Analysis.

  2017cited by this paper
• D‐β‐hydroxybutyrate promotes functional recovery and relieves pain hypersensitivity in mice with spinal cord injury

  2017cited by this paper
• The neuronal differentiation microenvironment is essential for spinal cord injury repair

  2017cited by this paper
• A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions.

  2017cited by this paper
• Mechanism of Neuroprotection Against Experimental Spinal Cord Injury by Riluzole or Methylprednisolone

  2017cited by this paper
• Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice

  2017cited by this paper
• Effects of propofol and dexmedetomidine anesthesia on Th1/Th2 of rat spinal cord injury.

  2017cited by this paper
• Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditions

  2017cited by this paper
• Traumatic spinal cord injury

  2017cited by this paper
• Atraumatic Spine Distraction Induces Metabolic Distress in Spinal Motor Neurons

  2017cited by this paper
• ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury.

  2017cited by this paper
• A Mouse Model of Bilateral Cervical Contusion-Compression Spinal Cord Injury

  2017cited by this paper
• The combined application of human adipose derived stem cells and Chondroitinase ABC in treatment of a spinal cord injury model.

  2017cited by this paper
• Animal models of spinal cord injury: a systematic review

  2017cited by this paper
• Rodent, large animal and non-human primate models of spinal cord injury.

  2017cited by this paper
• Intramedullary Lesion Length on Postoperative Magnetic Resonance Imaging is a Strong Predictor of ASIA Impairment Scale Grade Conversion Following Decompressive Surgery in Cervical Spinal Cord Injury

  2017cited by this paper
• Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury

  2017cited by this paper
• Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype

  2017cited by this paper
• Generating level-dependent models of cervical and thoracic spinal cord injury: Exploring the interplay of neuroanatomy, physiology, and function.

  2017cited by this paper

• Long-Term Management and Monitoring of the Bladder After Spinal Cord Injury in a Rodent Model

  2025cites this paper
• Spinal cord injury models: Advantages and disadvantages in the view of pathophysiology and clinical significance

  2025influential citation
• Effects of repetitive transcranial magnetic stimulation on apoptosis and MAPK/PI3K-AKT signaling pathways in rats with spinal cord injury.

  2025cites this paper
• Differential Gene Expression Across Species Following Spinal Cord Injury: A Systematic Review and Meta-Analysis

  2025cites this paper
• Combining clinically common drugs with hindlimb stretching in spinal cord injured rodents

  2024cites this paper
• Knockout of TNF-α in microglia decreases ferroptosis and convert microglia phenotype after spinal cord injury

  2024cites this paper
• Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos

  2023cites this paper