Endothelial Cell Dysfunction Leading to Diabetic Nephropathy: Focus on Nitric Oxide

No abstract is available for this paper.

• Publication year

  2001

• Venue

  HYPERTENSION

• Publication date

  2001-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.HYP.37.2.744PMID 11230367
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Delayed branching of endothelial capillary-like cords in glycated collagen I is mediated by early induction of PAI-1.

  2001cited by this paper
• [Nephropathy in type 2 diabetes mellitus].

  2000cited by this paper
• Microalbuminuria, blood pressure and diabetic renal disease: origin and development of ideas

  1999cited by this paper
• Endothelial cells in physiology and in the pathophysiology of vascular disorders.

  1998cited by this paper
• Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells

  1998cited by this paper
• Relationship between fasting plasma glucose, atherosclerosis risk factors and carotid intima media thickness in non-diabetic individuals

  1998cited by this paper
• Nephropathy of type-2 diabetes mellitus.

  1998cited by this paper
• Polymorphisms of angiotensin converting enzyme and plasminogen activator inhibitor-1 genes in diabetes and macroangiopathy1.

  1998cited by this paper
• Endothelial Dysfunction: Implications for Therapy of Cardiovascular Diseases

  1998cited by this paper
• Recent Progress in Advanced Glycation End Products and Diabetic Complications

  1997cited by this paper
• Nitric oxide in diabetic nephropathy.

  1997cited by this paper
• Future horizons in cardiovascular molecular therapeutics.

  1997cited by this paper
• Nitric Oxide and the Kidney

  1997cited by this paper
• NO in Diabetic Nephropathy

  1997cited by this paper
• Vascular effects of acute hyperglycemia in humans are reversed by L-arginine. Evidence for reduced availability of nitric oxide during hyperglycemia.

  1997cited by this paper
• Significance of tubulointerstitial changes in diabetic renal disease.

  1996cited by this paper
• Preglomerular sudanophilia in L-NAME hypertensive rats: involvement of endothelin.

  1996cited by this paper
• Molecular insights into renal interstitial fibrosis.

  1996cited by this paper
• Altered proliferation of retinal microvascular cells on glycated matrix.

  1995cited by this paper
• Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

  1995cited by this paper
• Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors.

  1995cited by this paper
• Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene.

  1995cited by this paper
• Nitric oxide activity in the human coronary circulation. Impact of risk factors for coronary atherosclerosis.

  1995cited by this paper
• Gene therapy inhibiting neointimal vascular lesion

  1995cited by this paper
• S-nitroso-N-acetylpenicillamine reduces leukocyte adhesion to type I collagen

  1994cited by this paper
• Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils.

  1994cited by this paper
• Nitric oxide released by platelets inhibits neutrophil B2 integrin function following acute carbon monoxide poisoning.

  1994cited by this paper
• L-arginine decreases the infiltration of the kidney by macrophages in obstructive nephropathy and puromycin-induced nephrosis.

  1994cited by this paper
• Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism.

  1994cited by this paper
• Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging.

  1994cited by this paper
• Structure-function relationships associated with extracellular matrix alterations in diabetic glomerulopathy.

  1994cited by this paper
• Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis.

  1994cited by this paper
• Topical hyperglycemia rapidly suppresses EDRF-mediated vasodilation of normal rat arterioles.

  1993cited by this paper
• The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.

  1993cited by this paper
• NITRIC OXIDE AND THE KIDNEY

  1993cited by this paper
• Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: a model for diabetic and aging complications.

  1992cited by this paper
• Nitric oxide: an endogenous modulator of leukocyte adhesion.

  1991cited by this paper
• Glycosylation products as toxic mediators of diabetic complications.

  1991cited by this paper
• Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

  1991cited by this paper
• Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis.

  1991cited by this paper
• Albuminuria reflects widespread vascular damage

  1989cited by this paper
• Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

  1989cited by this paper
• The microvascular extracellular matrix. Developmental changes during angiogenesis in the aortic ring-plasma clot model.

  1987cited by this paper
• Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries.

  1986cited by this paper
• Nonenzymatic glycosylation and the pathogenesis of diabetic complications.

  1984cited by this paper
• In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices

  1983cited by this paper
• Histotypic angiogenesis in vitro: Light microscopic, ultrastructural, and radioautographic studies

  1982cited by this paper
• The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

  1980cited by this paper

• The Role of TLRs in Obesity and Its Related Metabolic Disorders

  2025cites this paper
• Effect of On-Pump Versus Off-Pump Surgery on the Renal Function of Diabetic Patients: A Systematic Review

  2025cites this paper
• Integrated analysis of miRNA and mRNA expression profiles in diabetic mouse kidney treated to Korean Red Ginseng

  2022cites this paper
• Pathophysiologic Mechanisms and Potential Biomarkers in Diabetic Kidney Disease

  2022cites this paper
• Metabolomic Analysis of Serum and Tear Samples from Patients with Obesity and Type 2 Diabetes Mellitus

  2022cites this paper
• The efficacy of PDE5 inhibitors in diabetic patients

  2022cites this paper
• An overview of the efficacy and signaling pathways activated by stem cell-derived extracellular vesicles in diabetic kidney disease

  2022cites this paper
• Renoprotective Effect of Liraglutide Is Mediated via the Inhibition of TGF-Beta 1 in an LLC-PK1 Cell Model of Diabetic Nephropathy

  2022cites this paper
• Phenotypic diversity and metabolic specialization of renal endothelial cells

  2021cites this paper
• Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway.

  2021cites this paper
• Pathophysiology of diabetic kidney disease: impact of SGLT2 inhibitors

  2021cites this paper
• Homoarginine ameliorates diabetic nephropathy independent of nitric oxide synthase‐3

  2021cites this paper
• Incidence and Predictors of Chronic Kidney Disease among Diabetes Mellitus Patients: A Retrospective Follow-Up Study at a Tertiary Health-Care Setting of Ethiopia

  2021cites this paper
• Heart failure in diabetes.

  2021cites this paper
• Premature Ejaculation and Endocrine Disorders: A Literature Review

  2021cites this paper
• Acute Kidney Injury and Progressive Diabetic Kidney Disease: An Epidemiological Perspective

  2021cites this paper
• Enhancing Kidney DDAH-1 Expression by Adenovirus Delivery Reduces ADMA and Ameliorates Diabetic Nephropathy.

  2020cites this paper
• Microhemodynamic Parameters of Cortical Substance of Kidneys at Experimental Hydronephrosis

  2020cites this paper
• Some haematological parameters, manganese and zinc levels among diabetic patients of African descent attending Specialist Hospital Sokoto, Nigeria

  2019cites this paper
• Prolonged Exhaustion and Inadequate Food

  2019cites this paper
• Acute Kidney Injury and Progression of Diabetic Kidney Disease.

  2018cites this paper
• Plasma Ferritin Levels, Oxidative Stress and Nephropathy in Diabetes

  2018cites this paper
• Calcitonin and Omega-3 Fatty Acids Exhibit Antagonistic and Non-Additive Effects in Experimental Diabetes.

  2018cites this paper
• Some Haematological Parameters, Malondialdehyde and Glutathione Peroxidase Status of Diabetic Patients in Sokoto, Nigeria

  2018cites this paper
• Cardiovascular effects of sodium glucose cotransporter 2 inhibitors

  2018cites this paper
• Microvascular Damage and Hemodynamic Alterations in Diabetic Nephropathy

  2018cites this paper
• Nefropatia diabética não albuminúrica: uma via alternativa de lesão?

  2018cites this paper
• MEG3 damages fetal endothelial function induced by gestational diabetes mellitus via AKT pathway.

  2018cites this paper
• Arginase: A Multifaceted Enzyme Important in Health and Disease.

  2018cites this paper
• Vascular endothelium in diabetes.

  2017cites this paper
• Effects of chronic nitric oxide synthase inhibition on V’O2max and exercise capacity in mice

  2017cites this paper
• Endothelial Dysfunction Markers as Predictive of Nephropathy in Pediatric Type 1 Diabetes

  2017cites this paper
• Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Dovepress

  2017cites this paper
• Novel rhynchophylline analogues as microvascular relaxation agents for the treatment of microvascular dysfunction caused by diabetes.

  2017cites this paper
• High Glucose-Induced Hypomethylation Promotes Binding of Sp-1 to Myo-Inositol Oxygenase: Implication in the Pathobiology of Diabetic Tubulopathy.

  2017cites this paper
• Aryl Hydrocarbon Receptor Deficiency Attenuates Oxidative Stress-Related Mesangial Cell Activation and Macrophage Infiltration and Extracellular Matrix Accumulation in Diabetic Nephropathy

  2016cites this paper
• EFFECT OF HESPERETIN ON HYPERGLYCEMIA-MEDIATED OXIDATIVE DAMAGE IN THE HEPATIC AND RENAL TISSUES OF EXPERIMENTAL DIABETIC RATS

  2016cites this paper
• Premature ejaculation in type II diabetes mellitus patients: association with glycemic control

  2016cites this paper
• Genetic Targeting of Arginase-II in Mouse Prevents Renal Oxidative Stress and Inflammation in Diet-Induced Obesity

  2016cites this paper
• Synthesis and preliminary therapeutic evaluation of copper nanoparticles against diabetes mellitus and -induced micro- (renal) and macro-vascular (vascular endothelial and cardiovascular) abnormalities in rats

  2016cites this paper
• LXR agonist T0901317 upregulates thrombomodulin expression in glomerular endothelial cells by inhibition of nuclear factor‑κB.

  2016cites this paper
• Apelin and New-Onset Diabetes After Transplant in Living Kidney Allograft Recipients.

  2015cites this paper
• Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis

  2015cites this paper
• Renal Endothelial Dysfunction in Diabetic Nephropathy

  2015cites this paper
• Wen-Xin Decoction ameliorates vascular endothelium dysfunction via the PI3K/AKT/eNOS pathway in experimental atherosclerosis in rats

  2015cites this paper
• Nitric oxide in the normal kidney and in patients with diabetic nephropathy

  2015cites this paper
• Renal endothelial dysfunction in diabetic nephropathy.

  2014cites this paper
• Fisiopatología de la hiperfiltración glomerular en la diabetes. Parte 1

  2014cites this paper
• Alterations of the kidney cortex proteome in response to exercise training in normoglycemic and hyperglycemic conditions.

  2014cites this paper
• DIABETIC NEPHROPATHY AND DIABETIC RETINOPATHY AS MAJOR HEALTH BURDENS IN MODERN ERA

  2014cites this paper
• Patofisiología de la hiperfiltración glomerular en la diabetes. Parte II

  2014cites this paper
• Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.

  2014influential citation
• Promoting Effects of the Adipokine, Apelin, on Diabetic Nephropathy

  2013cites this paper
• Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism

  2013cites this paper
• Diabetic nephropathy: traditional to proteomic markers.

  2013cites this paper
• Relationship between serum nitric oxide and sialic acid in coexisted diabetes, hypertension and nephropathy.

  2013cites this paper
• Vascular response to vasodilator treatment in microalbuminuric diabetic kidney disease.

  2013cites this paper
• Gene Expression and Stereologic Analysis of Tubulointerstitial Remodeling in a Rodent Model of Chronic Proteinuria.

  2012cites this paper
• Mannose 6-Phosphate Receptor and Sortilin Mediated Endocytosis of α-Galactosidase A in Kidney Endothelial Cells

  2012cites this paper
• Involvement of the endothelin and nitric oxide systems in the pathogenesis of renal ischemic damage in an experimental diabetic model.

  2012cites this paper
• Title Mannose 6-phosphate receptor and sortilin mediatedendocytosis of α-galactosidase A in kidney endothelial cells

  2012cites this paper
• Glycemic control, dyslipidemia and endothelial dysfunction in coexisted diabetes, hypertension and nephropathy.

  2012cites this paper
• Coupled and Uncoupled Operational Mode of Nitric Oxide Synthase and the Regulation of the Sarcolemmal Na+- K+ ATPase: Receptor and Non-receptor Pathways

  2012cites this paper
• Glucagon-like peptide 1 protects microvascular endothelial cells by inactivating the PARP-1/iNOS/NO pathway.

  2011cites this paper
• Arginase-2 Mediates Diabetic Renal Injury

  2011cites this paper
• Polymorphisms of eNOS gene are associated with diabetic nephropathy: a meta-analysis.

  2011cites this paper
• Oxidative stress in early diabetic nephropathy: fueling the fire

  2011cites this paper
• Pathophysiology of the diabetic kidney.

  2011cites this paper
• Associations between cardio-ankle vascular index and microvascular complications in type 2 diabetes mellitus patients.

  2011cites this paper
• Targeted antioxidant therapies in hyperglycemia-mediated endothelial dysfunction.

  2011cites this paper
• Endothelial Progenitor Cells in Long-Standing Asymptomatic Type 1 Diabetic Patients with or without Diabetic Nephropathy

  2011cites this paper
• Insulin resistance of amino acid and protein metabolism in type 2 diabetes.

  2011cites this paper
• Human mesangial cells resist glycoxidative stress through an antioxidant response.

  2011cites this paper
• DIABETIC NEPHROPATHY- PATHOGENESIS AND NEWER TARGETS IN TREATMENT Review Article

  2011cites this paper
• Endothelial Dysfunction, Inflammation, and Apoptosis in Diabetes Mellitus

  2010cites this paper
• Nitric Oxide Synthesis Is Reduced in Subjects With Type 2 Diabetes and Nephropathy

  2010influential citation
• Gene Expression Programs of Mouse Endothelial Cells in Kidney Development and Disease

  2010cites this paper
• Microalbuminuria is not associated with endothelial dysfunction and coronary atherosclerosis in patients with acute coronary syndromes

  2010cites this paper
• Serum Nitric Oxide and Sialic Acid: Possible Biochemical Markers for Progression of Diabetic Nephropathy

  2010cites this paper
• Diabetes Mellitus is Not Only A Risk Factor But A Cardiovascular Disease

  2010cites this paper
• Nitric oxide synthesis is reduced in subjects with Type 2 Diabetes and nephropathy Short running title: Insulin-resistance to NO metabolism in T2DM

  2010cites this paper
• Vascular endothelial dysfunction: a tug of war in diabetic nephropathy?

  2009cites this paper
• Asymmetric dimethylarginine is closely associated with the development and progression of nephropathy in patients with type 2 diabetes.

  2009cites this paper
• Diabetes and Hypertension: Correlation Between Glycosylated Hemoglobin (HbA1c) and Serum Nitric Oxide (NO),

  2009cites this paper
• Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus.

  2009cites this paper
• Value of Plasma Level of Endothelin-1 and Nitric Oxide in Diabetic Nephropathy

  2009cites this paper
• The role of microalbuminuria and insulin resistance as significant risk factors for white matter lesions in Japanese type 2 diabetic patients

  2008cites this paper
• Overexpression of calmodulin in pancreatic beta cells induces diabetic nephropathy.

  2008cites this paper
• Hyperglycemia induces apoptosis of human pancreatic islet endothelial cells: effects of pravastatin on the Akt survival pathway.

  2008cites this paper
• Renal Activity of Akt Kinase in Obese Zucker Rats

  2008cites this paper
• Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal endothelial function in patients with type 2 diabetes

  2008cites this paper
• The anti-atherogenic effects of thiazolidinediones.

  2007cites this paper
• Correlations of urinary albumin excretion and atherosclerosis in Japanese type 2 diabetic patients.

  2007cites this paper
• Papel do exercício físico na disfunção endotelial de pacientes com síndrome metabólica e Diabetes mellitus

  2007cites this paper
• Hipertensão arterial, aterosclerose e inflamação: o endotélio como órgão-alvo Arterial hypertension, atherosclerosis and inflammation: the endothelium as target organ

  2007cites this paper
• Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis

  2007cites this paper
• Diabetes and Angiogenesis

  2007cites this paper
• Two-week treatment with pravastatin improves ventriculo-vascular haemodynamic interactions in young men with type 1 diabetes

  2007cites this paper
• Endothelial dysfunction in insulin resistance : the role of EDHF and gap junction communication

  2007cites this paper
• Pharmacological mechanisms involved in the vasodilator effects of extracts from Echinodorus grandiflorus.

  2007cites this paper