The metabolic syndrome in overweight epileptic patients treated with valproic acid

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Epilepsia

• Publication date

  2010-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1528-1167.2009.02206.xPMID 19682024
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Metabolic Complications of Childhood Obesity

  2008cited by this paper
• Prevalence and risk factors of metabolic syndrome in obese children and adolescents: the role of the severity of obesity

  2008influential reference
• Increased oxidative stress in epileptic children treated with valproic acid.

  2008cited by this paper
• Insulin resistance and obesity in childhood.

  2008cited by this paper
• Development of insulin resistance and its relation to diet in the obese child

  2007cited by this paper
• Characterization of Insulin Secretion in Valproate‐treated Patients with Epilepsy

  2006cited by this paper
• Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr)

  2006cited by this paper
• Insulin-related metabolic changes during treatment with valproate in patients with epilepsy.

  2006cited by this paper
• Valproate-induced Insulin Resistance in Prepubertal Girls with Epilepsy

  2005cited by this paper
• Molecular mediators of hepatic steatosis and liver injury.

  2004cited by this paper
• Comparison of a low-fat diet to a low-carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in free-living, overweight men and women.

  2004influential reference
• Prevalence of the insulin resistance syndrome in obesity

  2004cited by this paper
• The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity.

  2004cited by this paper
• Lamotrigine Versus Valproate Monotherapy—Associated Weight Change in Adolescents With Epilepsy: Results From a Post Hoc Analysis of a Randomized, Double-Blind Clinical Trial

  2003influential reference
• Valproic acid-associated weight gain in older children and teens with epilepsy.

  2003cited by this paper
• Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia.

  2003cited by this paper
• Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994.

  2003influential reference
• Obesity, insulin resistance, diabetes, and cardiovascular risk in children: an American Heart Association scientific statement from the Atherosclerosis, Hypertension, and Obesity in the Young Committee (Council on Cardiovascular Disease in the Young) and the Diabetes Committee (Council on Nutrition,

  2003cited by this paper
• Epidemiology, implications and mechanisms underlying drug-induced weight gain in psychiatric patients.

  2003influential reference
• The foetal origins of the metabolic syndrome--a South African perspective.

  2002cited by this paper
• Italian cross-sectional growth charts for height, weight and BMI (6–20 y)

  2002cited by this paper
• Session 2: Type 2 Diabetes and MODY

  2002cited by this paper
• Serum Insulin and Leptin Levels in Valproate‐associated Obesity

  2002influential reference
• Insulin Resistance in Epileptic Girls Who Gain Weight After Therapy With Valproic Acid

  2002cited by this paper
• Diabetes Therapeutics News

  2002cited by this paper
• Insulin resistance in childhood obesity.

  2002cited by this paper
• Early programming of glucose-insulin metabolism.

  2002cited by this paper
• Prevalence of impaired glucose tolerance among children and adolescents with marked obesity.

  2002cited by this paper
• Longitudinal study on pubertal insulin resistance.

  2001cited by this paper
• Presence of metabolic cardiovascular syndrome in obese children

  2000cited by this paper
• Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance.

  1999cited by this paper
• Serum leptin changes in epileptic patients who gain weight after therapy with valproic acid

  1999influential reference
• Risk of Excessive Weight Gain in Epileptic Children Treated with Valproate

  1999cited by this paper
• Valproate, lamotrigine, and insulin‐mediated risks in women with epilepsy

  1998cited by this paper
• Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation

  1998cited by this paper
• Distributions and trends of serum lipid levels among United States children and adolescents ages 4-19 years: data from the Third National Health and Nutrition Examination Survey.

  1998cited by this paper
• Acute Effects of Insulin in the Control of VLDL Production in Humans: Implications for the insulin-resistant state

  1996cited by this paper
• Differences in lipolysis between human subcutaneous and omental adipose tissues.

  1995cited by this paper
• Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy.

  1994influential reference
• Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians.

  1993cited by this paper
• Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state.

  1992cited by this paper
• [Insulin resistance in childhood obesity].

  1992cited by this paper
• Seasonal variations of glycosylated haemoglobin in diabetic children

  1989cited by this paper
• Role of Insulin Resistance in Human Disease

  1988cited by this paper
• Banting lecture 1988. Role of insulin resistance in human disease.

  1988cited by this paper
• Sodium Valproate: Monotherapy and Polytherapy

  1982cited by this paper
• Effects of sodium valproate in 100 children with special reference to weight.

  1981cited by this paper
• Valproate induced changes in GABA metabolism at the subcellular level.

  1981cited by this paper
• Fractionation of human serum lipoproteins by single-spin gradient ultracentrifugation: quantification of apolipoproteins B and A-1 and lipid components.

  1977influential reference
• Determinants of human adipose tissue lipoprotein lipase. Effect of diabetes and obesity on basal- and diet-induced activity.

  1975cited by this paper
• Variations in the Pattern of Pubertal Changes in Boys

  1970cited by this paper
• Variations in pattern of pubertal changes in girls.

  1969cited by this paper

• Association between dietary fiber intake and gallstones among American adults: a cross-sectional study

  2025cites this paper
• Is Cardiovascular Mortality Among People with Epilepsy increasing? A retrospective US population study

  2025cites this paper
• Treatment with brivaracetam has no apparent long‐term effects on body weight in pediatric patients with epilepsy

  2024cites this paper
• Tiny pills, big impacts: A systematic review on the endocrine disrupting effects of paediatric pharmaceuticals.

  2024cites this paper
• Association of dietary fiber intake with epileptic seizures in U.S. adults: A Population-base study of 13,277 participants.

  2024cites this paper
• Cardiometabolic biomarkers and comorbid metabolic syndrome in schizophrenia: A cross-sectional study of long-term clozapine/olanzapine users.

  2024cites this paper
• Obesity and Metabolic Syndrome in Patients with Epilepsy, their Relation with Epilepsy Control

  2023cites this paper
• Drug-induced hyperglycemia and diabetes.

  2023cites this paper
• A novel marker to predict cardiac arrhythmia in epilepsy patients: frontal QRS-T angle.

  2023cites this paper
• The Study of Carotid Artery Intima-Media Thickness in Children With Epilepsy on Anti-Epileptic Drugs

  2023cites this paper
• Association of Long-term Antiseizure Medication Use and Incident Type 2 Diabetes Mellitus

  2023cites this paper
• A Leading Cause of Epilepsy

  2023cites this paper
• Post­‑stroke epilepsy

  2023cites this paper
• Metabolic syndrome and its associated factors among epileptic patients at Dessie Comprehensive Specialized Hospital, Northeast Ethiopia; a hospital-based comparative cross-sectional study

  2022cites this paper
• Effect of Sodium Valproate on Weight, Body Mass Index, Uric Acid, Vitamin D3, Blood Insulin, and Serum Lipid Profile in Children

  2022cites this paper
• Cross sectional descriptive study to study the prevalence of metabolic syndrome among patients with epilepsy on antiepileptic drugs in a tertiary care centre

  2022cites this paper
• effect of patient’s characteristics on CYP2C19 polymorphisms based on weight and gender groups of epileptic seizure patients taking divalproex sodium

  2022cites this paper
• Insulin Resistance in children on Sodium Valproate – A hospital based cross-sectional study in Indian children

  2022cites this paper
• Effect of long-term valproic acid therapy on lipid profiles in paediatric patients with epilepsy: a meta-analysis

  2022cites this paper
• Relationship between CYP2C19 polymorphisms and weight gain in epilepsy patients treated with divalproex sodium: does gender matter?

  2022cites this paper
• The effects of valproate on serum leptin, insulin, and lipid levels in epileptic children

  2021cites this paper
• Analysis of gut microbiota in patients with epilepsy treated with valproate: Results from a three months observational prospective cohort study.

  2021cites this paper
• Effects of Long-term Antiepileptic Therapy on Carotid Artery Intima- Media Thickness

  2021cites this paper
• Zonisamide Therapy Reduces Metabolic Consequences and Diminishes Nonalcoholic Fatty Liver Disease in Patients with Epilepsy

  2021cites this paper
• Associations of overweight and obesity with drug-resistant epilepsy.

  2021cites this paper
• Incidence of the Metabolic Syndrome among Patients with Epilepsy Attending a Neuropsychiatric Hospital in Kigali, Rwanda

  2021cites this paper
• Epilepsy, antiepileptic drugs, and the risk of major cardiovascular events

  2021cites this paper
• Cardiometabolic factors in pediatric patients with chronic diseases.

  2021cites this paper
• Frequency of metabolic syndrome and insulin resistance in epileptic patients treated with sodium valproate or carbamazepine monotherapy: A Case-Control Study 

  2021cites this paper
• Metabolic syndrome in people with epilepsy.

  2020cites this paper
• Medication-induced hyperglycemia: pediatric perspective

  2020cites this paper
• Metabolic syndrome and obstructive sleep apnea syndrome among patients with epilepsy on monotherapy.

  2020cites this paper
• Longitudinal changes in insulin resistance in children with epilepsy on ketogenic diet: Prevalence and risk factors.

  2020cites this paper
• Effects of Valproic Acid on Selected Kidney Function Indices in Rats

  2020cites this paper
• Evaluation of The Metabolic Syndrome Criteria And Body Composition in Ambulatory Children with Epilepsy UsingSodium Valproate and Carbamazepine In Southern Iran: A Case-Control Study

  2020influential citation
• Cerebrovascular Disease; A Leading Cause of Epilepsy

  2020cites this paper
• Influence of sodium valproate treatment on body mass and insulin resistance parameters in children with epilepsy

  2020cites this paper
• Recent advancement in the discovery and development of anti-epileptic biomolecules: An insight into structure activity relationship and Docking.

  2020cites this paper
• Evaluation of factors influencing obesity and the effect of a 12-week home-based exercise program in people with epilepsy - Randomized control trial.

  2020cites this paper
• Animal Models of Metabolic Epilepsy and Epilepsy Associated Metabolic Dysfunction: A Systematic Review

  2020cites this paper
• Medication Use and the Risk of Newly Diagnosed Diabetes in Patients with Epilepsy: A Data Mining Application on a Healthcare Database

  2020cites this paper
• Insulin Resistance in Chronic Disease

  2019cites this paper
• Medikamenteninduzierter Diabetes mellitus

  2019cites this paper
• Impact of Drugs on Diabetes Risk and Glycemic Control

  2019cites this paper
• Lipidomic Profiling Reveals Disruption of Lipid Metabolism in Valproic Acid-Induced Hepatotoxicity

  2019cites this paper
• Valproic Acid and Epilepsy: From Molecular Mechanisms to Clinical Evidences

  2019cites this paper
• Moving beyond sodium valproate: choosing the right anti-epileptic drug in children

  2019cites this paper
• Endoplasmic Reticulum Stress-induced Upregulation of STARD1 Promotes Acetaminophen-induced Acute Liver Failure.

  2019cites this paper
• Mitochondrial Dysfunction in Drug‐Induced Liver Injury

  2018cites this paper
• Serum Homocysteine Level and Lipid Profile in Migraine Patients Treated with Sodium Valproate

  2018cites this paper
• Psychotropic use and risk of stroke among patients with bipolar disorders: 10-year nationwide population based study.

  2018cites this paper
• Biochemical derangements related to metabolic syndrome in epileptic patients on treatment with valproic acid.

  2018cites this paper
• The effects of valproate and topiramate use on serum insulin, leptin, neuropeptide Y and ghrelin levels in epileptic children.

  2018cites this paper
• The impact of valproic acid treatment on weight gain in pediatric patients with epilepsy.

  2017cites this paper
• Assessment of atherosclerotic risk among patients with epilepsy on valproic acid, lamotrigine, and carbamazepine treatment

  2017cites this paper
• Nutritional status and metabolic profile in neurologically impaired pediatric surgical patients

  2017cites this paper
• Metabolic effects of acute and chronic treatment with valproic acid in people with epilepsy

  2017cites this paper
• Diagnostic Yield and Accuracy of Different Metabolic Syndrome Criteria in Adult Patients with Epilepsy

  2017cites this paper
• Effect of valproic acid on metabolic status and endocrine system in pediatric patients with epilepsy: systematic literature review

  2017cites this paper
• Does Valproic Acid Have Potential in the Treatment of Diabetes Mellitus?

  2017cites this paper
• Effect of antiepileptic drug (valproic acid) on children growth

  2016cites this paper
• Metabolic syndrome and anticonvulsants: A comparative study of valproic acid and carbamazepine.

  2016cites this paper
• Metabolic syndrome in young adults with epilepsy.

  2016cites this paper
• Drug therapy of epileptic seizures among adult epileptic outpatients of University of Gondar Referral and Teaching Hospital, Gondar, North West Ethiopia

  2016cites this paper
• The New Antiepileptic Drugs: Their Neuropharmacology and Clinical Indications

  2016cites this paper
• Post-epilepsy stroke: A review

  2016cites this paper
• ASSESSMENT OF ANTHROPOMETRIC PROFILE OF EPILEPTIC ADULT POPULATION OF TIRUPATI REGION

  2016cites this paper
• Improvement of oral contraceptive-induced glucose dysregulation and dyslipidemia by valproic acid is independent of circulating corticosterone

  2016cites this paper
• Weight gain in children on oxcarbazepine monotherapy.

  2016cites this paper
• Valproic acid and nonalcoholic fatty liver disease: A possible association?

  2015cites this paper
• Possible association between moderate intellectual disability and weight gain in valproic acid–treated patients with epilepsy

  2015cites this paper
• Drug-Induced Hyperglycaemia and Diabetes

  2015cites this paper
• Serum Lipids and Thyroid Functions in Young Epileptic Patients Undergoing Monotherapy with Valproate or Levetiracetam

  2015cites this paper
• Association of LEPR and ANKK1 Gene Polymorphisms with Weight Gain in Epilepsy Patients Receiving Valproic Acid

  2015cites this paper
• Antiepileptic drugs and the risk of ischaemic stroke and myocardial infarction: a population-based cohort study

  2015cites this paper
• Parameters of metabolic syndrome in Indian children with epilepsy on valproate or phenytoin monotherapy

  2015cites this paper
• Valproic Acid as a potentiator of metabolic syndrome in institutionalized residents on concomitant antipsychotics: fat chance, or slim to none?

  2015cites this paper
• Insulin resistance in patients on valproic acid: relation to adiponectin

  2015cites this paper
• [The prevalence of obesity and metabolic syndrome in paediatric patients with epilepsy treated in monotherapy with valproic acid].

  2015cites this paper
• ANTHROPOMETRIC PROFILE AND NUTRITIONAL INTAKE IN PATIENTS WITH EPILEPSY.

  2015cites this paper
• Reproductive Hormones in Epilepsy Therapy: From Old Promises to New Hopes

  2015cites this paper
• Somatic co‐morbidities in epilepsy

  2015cites this paper
• Obesity and Epilepsy

  2015cites this paper
• Prevalencia de obesidad y síndrome metabólico en pacientes pediátricos con epilepsia tratados en monoterapia con ácido valproico

  2015cites this paper
• Genetic Exploration of Valproate Induced Weight Gain

  2015cites this paper
• Quality of care measures in multimorbidity.

  2014cites this paper
• The effects of antiepileptic drugs on vascular risk factors: a narrative review.

  2014cites this paper
• Comparison of the Metabolic Syndrome Risk in Valproate-Treated Patients with Epilepsy and the General Population in Estonia

  2014cites this paper
• Effect of Antiepilepsy Drug Therapy on Ventricular Function in Children With Epilepsy: A Tissue Doppler Imaging Study

  2014cites this paper
• Study of effects of antiepileptic therapy on various biochemical and hematological parameters patients suffering of epilepsy

  2014cites this paper
• Weight and fat distribution in patients taking valproate: A valproate‐discordant gender‐matched twin and sibling pair study

  2014influential citation
• A Possible Association of Sex Hormone-Binding Globulin with Weight Gain in the Valproic Acid-Treated Female Patients with Epilepsy

  2014cites this paper
• The use of psychiatric drugs and worsening body mass index among inpatients with schizophrenia

  2014cites this paper
• The Long-Term Safety of Antiepileptic Drugs

  2013cites this paper
• Class I Lysine Deacetylases Facilitate Glucocorticoid Receptor-Mediated Transcriptional Activation

  2013cites this paper
• Effects of Longterm Antiepileptic Drugs on Vascular Risk Factors and Atherosclerosis.

  2013cites this paper
• Metabolic and endocrine effects of valproic acid chronic treatment.

  2013cites this paper
• Interictal 12-lead electrocardiography in patients with epilepsy.

  2013cites this paper
• Adverse drug reactions induced by valproic acid.

  2013cites this paper
• Evaluation of Oral Glucose Tolerance Test in Children With Epilepsy

  2013cites this paper