High-level bacterial expression of human glutathione transferase P1-1 encoded by semisynthetic DNA.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Protein Expression and Purification

• Publication date

  1995-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1006/PREP.1995.1034PMID 7663160
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases.

  1994cited by this paper
• Isoenzyme-specific quantitative immunoassays for cytosolic glutathione transferases and measurement of the enzymes in blood plasma from cancer patients and in tumor cell lines.

  1994cited by this paper
• A pilot study of pi-class glutathione S-transferase expression in breast cancer: correlation with estrogen receptor expression and prognosis in node-negative breast cancer.

  1993cited by this paper
• Nomenclature for human glutathione transferases.

  1992cited by this paper
• Expression of glutathione transferase pi as a predictor for treatment results at different stages of acute nonlymphoblastic leukemia.

  1992cited by this paper
• Design of two chimaeric human-rat class alpha glutathione transferases for probing the contribution of C-terminal segments of protein structure to the catalytic properties.

  1992cited by this paper
• Heterologous expression of the allelic variant mu-class glutathione transferases mu and psi.

  1991cited by this paper
• High-level translation initiation.

  1990cited by this paper
• Differences among human tumor cell lines in the expression of glutathione transferases and other glutathione-linked enzymes.

  1990cited by this paper
• Primary and secondary structural analyses of glutathione S-transferase pi from human placenta.

  1990cited by this paper
• Codon preferences in free-living microorganisms.

  1990cited by this paper
• Isolation of a cDNA clone and localization of the human glutathione S‐transferase 3 genes to chromosome bands 11q13 and 12q13‐14

  1989cited by this paper
• Glutathione S-transferase isoenzymes in human tumours and tumour derived cell lines.

  1989cited by this paper
• Translation of the sequence AGG-AGG yields 50% ribosomal frameshift.

  1988cited by this paper
• Identification of an anionic form of glutathione transferase present in many human tumors and human tumor cell lines.

  1988cited by this paper
• Isolation of the human anionic glutathione S-transferase cDNA and the relation of its gene expression to estrogen-receptor content in primary breast cancer.

  1988cited by this paper
• The structure of the human glutathione S-transferase pi gene.

  1988cited by this paper
• Characterization of multidrug resistance in SEWA mouse tumor cells: increased glutathione transferase activity and reversal of resistance with verapamil.

  1987cited by this paper
• Expression of class Pi glutathione transferase in human malignant melanoma cells.

  1987cited by this paper
• The separation of glutathione transferase subunits by using reverse-phase high-pressure liquid chromatography.

  1987cited by this paper
• Structure and expression of a human class pi glutathione S-transferase messenger RNA.

  1987cited by this paper
• Organ distribution of glutathione transferase isoenzymes in the human fetus: differences between liver and extrahepatic tissues.

  1986cited by this paper
• Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

  1986cited by this paper
• The human glutathione S-transferases: Developmental aspects of the GST1, GST2, and GST3 loci

  1985cited by this paper
• Regulation of ribosomal RNA promoters with a synthetic lac operator.

  1984cited by this paper
• Solubilization and immune-detection of beta-galactosidase hybrid proteins carrying foreign antigenic determinants.

  1983cited by this paper
• Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli.

  1983cited by this paper
• Purification of a new glutathione S-transferase (transferase mu) from human liver having high activity with benzo(alpha)pyrene-4,5-oxide.

  1981cited by this paper
• Glutathione S-transferase (transferase pi) from human placenta is identical or closely related to glutathione S-transferase (transferase rho) from erythrocytes.

  1981cited by this paper
• Glutathione S-transferase activity in human placenta.

  1980cited by this paper
• Identification of a new glutathione S-transferase in human liver.

  1980cited by this paper
• Purification of glutathione-S-transferase from human placenta.

  1979cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• A simplification of the protein assay method of Lowry et al. which is more generally applicable.

  1977cited by this paper

• Human GST P1-1 Redesigned for Enhanced Catalytic Activity with the Anticancer Prodrug Telcyta and Improved Thermostability

  2024cites this paper
• Exploring the inhibitory potential of hormone replacement therapy drugs on glutathione transferase P1-1

  2024influential citation
• Evaluation of Phenolic Content Diversity along with Antioxidant/Pro-Oxidant, Glutathione Transferase Inhibition, and Cytotoxic Potential of Selected Commonly Used Plants

  2022influential citation
• Preparation and characterization of recombinant human glutathione transferase P1 and screening of novel enzyme inhibitors

  2021cites this paper
• Mutational Analysis of the Binding of Alternative Substrates and Inhibitors to the Active Site of Human Glutathione Transferase P1–1

  2020cites this paper
• Design and synthesis of 2-substituted-5-(4-trifluoromethylphenyl-sulphonamido)benzoxazole derivatives as human GST P1-1 inhibitors

  2018cites this paper
• Synthesis and activity mechanism of some novel 2-substituted benzothiazoles as hGSTP1-1 enzyme inhibitors$

  2017cites this paper
• Exploring sequence-function space of a poplar glutathione transferase using designed information-rich gene variants

  2017cites this paper
• Model Studies on Peroxidic Glutathione Transferase (GST) Inhibitors: C5‐Methylated 1,2,4‐Trioxanes with C6‐Acrylate Side Chains

  2015cites this paper
• Identification of new inhibitors for human hematopoietic prostaglandin D2 synthase among FDA-approved drugs and other compounds.

  2015cites this paper
• Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents

  2015cites this paper
• Drosophila GSTs display outstanding catalytic efficiencies with the environmental pollutants 2,4,6-trinitrotoluene and 2,4-dinitrotoluene

  2015influential citation
• Synthesis and Biological Evaluation of 2‐Substituted‐5‐(4‐nitrophenylsulfonamido)benzoxazoles as Human GST P1‐1 Inhibitors, and Description of the Binding Site Features

  2014cites this paper
• FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

  2013cites this paper
• Inhibition of human glutathione transferase P1-1 by novel benzazole derivatives

  2012cites this paper
• Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1.

  2008cites this paper
• Detection and biochemical characterisation of a novel polymorphism in the human GSTP1 gene.

  2007cites this paper
• Human glutathione transferases catalyzing the bioactivation of anticancer thiopurine prodrugs.

  2007cites this paper
• Replacement surgery with unnatural amino acids in the lock-and-key joint of glutathione transferase subunits.

  2006cites this paper
• Inhibition of human glutathione transferases by multidrug resistance chemomodulators in vitro

  2006cites this paper
• Peptide phage display for probing GST-protein interactions.

  2005cites this paper
• Optimizing the heterologous expression of glutathione transferase.

  2005cites this paper
• Functional Role of the Lock and Key Motif at the Subunit Interface of Glutathione Transferase P1-1*

  2004cites this paper
• Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts.

  2003cites this paper
• Purification and Characterisation of Two GST'S Forms from Rhizobium Leguminosarum with a High Affinity to Herbicides

  2003cites this paper
• Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1*

  2003cites this paper
• Selective Recognition of Peptide Sequences by Glutathione Transferases: A Possible Mechanism for Modulation of Cellular Stress-Induced Signaling Pathways

  2003cites this paper
• A novel glutathione transferase from Haemophilus influenzae which has high affinity towards antibiotics.

  2002cites this paper
• Inhibition of glutathione S‐transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance

  2002cites this paper
• Design of a monomeric human glutathione transferase GSTP1, a structurally stable but catalytically inactive protein.

  2002cites this paper
• Disorder-to-order transition of the active site of human class Pi glutathione transferase, GST P1-1.

  2001cites this paper
• Proposed reductive metabolism of artemisinin by glutathione transferases in vitro

  2001cites this paper
• Tyrosine 50 at the subunit interface of dimeric human glutathione transferase P1-1 is a structural key residue for modulating protein stability and catalytic function.

  2000cites this paper
• A Conserved “Hydrophobic Staple Motif” Plays a Crucial Role in the Refolding of Human Glutathione Transferase P1-1*

  2000cites this paper
• Studies on the differential inhibition of glutathione conjugate formation of (+)-anti-benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide and 1-chloro-2,4-dinitrobenzene in V79 Chinese hamster cells.

  2000cites this paper
• Structures of thermolabile mutants of human glutathione transferase P1-1.

  2000cites this paper
• Structural characterization of acid-induced intermediates of human glutathione transferase P1-1.

  2000cites this paper
• Use of silent mutations in cDNA encoding human glutathione transferase M2-2 for optimized expression in Escherichia coli.

  1999cites this paper
• Catalytic Efficiency of Glutathione Transferase P1-1 Variants Towards Bay- and Fjord-Region Diol Epoxides of Polycyclic Aromatic Hydrocarbons

  1999cites this paper
• Expression and purification of hexahistidine-tagged human glutathione S-transferase P1-1 in Escherichia coli.

  1999cites this paper
• Optimized heterologous expression of glutathione reductase from Cyanobacterium anabaena PCC 7120 and characterization of the recombinant protein.

  1999cites this paper
• Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons.

  1998cites this paper
• The mRNA for GST Pi from FRHK rhesus monkey kidney cells codes for an enzyme with activity towards 1-chloro-2,4-dinitrobenzene in spite of an I68F mutation.

  1998cites this paper
• Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105.

  1998cites this paper
• Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases.

  1998cites this paper
• Ligand‐based protein alignment and isozyme specificity of glutathione S‐transferase inhibitors

  1997cites this paper
• Molecular Cloning, Characterization, and Expression in Escherichia coli of Full-length cDNAs of Three Human Glutathione S-Transferase Pi Gene Variants

  1997cites this paper
• The Conserved N-capping Box in the Hydrophobic Core of Glutathione S-Transferase P1–1 Is Essential for Refolding

  1997cites this paper
• Conjugation of highly reactive aflatoxin B1 exo-8,9-epoxide catalyzed by rat and human glutathione transferases: estimation of kinetic parameters.

  1997cites this paper
• Reduction of thymine hydroperoxide by phospholipid hydroperoxide glutathione peroxidase and glutathione transferases

  1997cites this paper
• Optimized heterologous expression of the polymorphic human glutathione transferase M1-1 based on silent mutations in the corresponding cDNA.

  1996cites this paper
• Glubodies: randomized libraries of glutathione transferase enzymes.

  1996cites this paper
• Optimized heterologous expression of the human zinc enzyme glyoxalase I.

  1996cites this paper
• Isothiocyanates as substrates for human glutathione transferases: structure-activity studies.

  1995cites this paper