Identification and analysis of the plant peroxisomal targeting signal 1 receptor NtPEX5.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1998-10-27

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1073/PNAS.95.22.13336PMID 9789089PMCID PMC23804
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Difference in Recognition of Terminal Tripeptides as Peroxisomal Targeting Signal 1 between Yeast and Human Is Due to Different Affinities of Their Receptor Pex5p to the Cognate Signal and to Residues Adjacent to It*

  1998cited by this paper
• Protein Transport into Higher Plant Peroxisomes (In Vitro Import Assay Provides Evidence for Receptor Involvement)

  1997cited by this paper
• Identification of the peroxisomal targeting signal for cottonseed catalase.

  1997cited by this paper
• Pex14p is a member of the protein linkage map of Pex5p

  1997cited by this paper
• Diverse Amino Acid Residues Function within the Type 1 Peroxisomal Targeting Signal (Implications for the Role of Accessory Residues Upstream of the Type 1 Peroxisomal Targeting Signal)

  1997cited by this paper
• Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways.

  1997cited by this paper
• Changes in targeting efficiencies of proteins to plant microbodies caused by amino acid substitutions in the carboxy-terminal tripeptide.

  1997cited by this paper
• A unified nomenclature for peroxisome biogenesis factors

  1996cited by this paper
• The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins

  1996cited by this paper
• Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor

  1996cited by this paper
• Targeting and processing of a chimeric protein with the N-terminal presequence of the precursor to glyoxysomal citrate synthase.

  1996cited by this paper
• Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor

  1996cited by this paper
• cDNA cloning and expression of a gene for 3-ketoacyl-CoA thiolase in pumpkin cotyledons

  1996cited by this paper
• Labeling of peroxisomes with green fluorescent protein in living P. pastoris cells.

  1996cited by this paper
• Immunogold labeling of yeast cells: an efficient tool for the study of protein targeting and morphological alterations due to overexpression and inactivation of genes

  1996cited by this paper
• Protein Translocation into Peroxisomes*

  1996cited by this paper
• Tetratrico peptide repeat interactions: to TPR or not to TPR?

  1995cited by this paper
• BEAUTY: an enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results.

  1995cited by this paper
• Identification and Characterization of the Putative Human Peroxisomal C-terminal Targeting Signal Import Receptor (*)

  1995cited by this paper
• Comparison of methods for searching protein sequence databases

  1995cited by this paper
• Peroxisomes and their Assembly in Higher Plants

  1995cited by this paper
• How proteins penetrate peroxisomes.

  1995cited by this paper
• Specific binding of the peroxisomal protein targeting sequence to glyoxysomal membranes.

  1994cited by this paper
• Mutational analysis of the N-terminal topogenic signal of watermelon glyoxysomal malate dehydrogenase using the heterologous host Hansenula polymorpha.

  1994cited by this paper
• Conservative amino acid substitutions of the C-terminal tripeptide (Ala-Arg-Met) on cottonseed isocitrate lyase preserve import in vivo into mammalian cell peroxisomes.

  1994cited by this paper
• The tetratricopeptide repeat-domain of the PAS10 protein of Saccharomyces cerevisiae is essential for binding the peroxisomal targeting signal-SKL.

  1994cited by this paper
• Construction of an improved host strain for two hybrid screening.

  1994cited by this paper
• Two independent peroxisomal targeting signals in catalase A of Saccharomyces cerevisiae

  1993cited by this paper
• Targeting of castor bean glyoxysomal isocitrate lyase to tobacco leaf peroxisomes

  1993cited by this paper
• Protein import into peroxisomes and biogenesis of the organelle.

  1993cited by this paper
• Targeting of glyoxysomal proteins to peroxisomes in leaves and roots of a higher plant.

  1993cited by this paper
• Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun.

  1992cited by this paper
• A novel genetic system to detect protein–protein interactions

  1989cited by this paper
• Molecular cloning : a laboratory manual. Cold Spring Harbor, NY

  1989cited by this paper
• Identification of a peroxisomal targeting signal at the carboxy terminus of firefly luciferase

  1987cited by this paper
• Immunocytochemical Analysis Shows that Glyoxysomes Are Directly Transformed to Leaf Peroxisomes during Greening of Pumpkin Cotyledons.

  1986cited by this paper
• Yeast/E. coli shuttle vectors with multiple unique restriction sites

  1986cited by this paper
• Investigation of the glyoxysome-peroxisome transition in germinating cucumber cotyledons using double-label immunoelectron microscopy

  1985cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Experiments in molecular genetics

  1972cited by this paper

• A non-canonical fungal peroxisome PTS-1 signal, SYM, and its evolutionary aspects

  2025cites this paper
• Identification of Auxiliary Organellar Targeting Signals for Plant Peroxisomes Using Bioinformatic Analysis of Large Protein Sequence Datasets Followed by Experimental Validation.

  2024cites this paper
• Peroxisomal Localization of Benzyl Alcohol O-Benzoyltransferase HSR201 is Mediated by a Non-canonical Peroxisomal Targeting Signal and Required for Salicylic Acid Biosynthesis

  2024cites this paper
• Engineering yeast for the de novo synthesis of jasmonates

  2023cites this paper
• Modulation in gene expression and enzyme activity suggested the roles of monodehydroascorbate reductase in development and stress response in bread wheat.

  2023cites this paper
• Defining upstream enhancing and inhibiting sequence patterns for plant peroxisome targeting signal type 1 using large‐scale in silico and in vivo analyses

  2022cites this paper
• Ubiquitin-conjugating activity by PEX4 is required for efficient protein transport to peroxisomes in Arabidopsis thaliana

  2022cites this paper
• Evolutionary Maintenance of the PTS2 Protein Import Pathway in the Stramenopile Alga Nannochloropsis

  2020cites this paper
• The type-2 peroxisomal targeting signal.

  2019cites this paper
• A Mechanistic Perspective on PEX1 and PEX6, Two AAA+ Proteins of the Peroxisomal Protein Import Machinery

  2019cites this paper
• Distinct Roles for Peroxisomal Targeting Signal Receptors Pex5 and Pex7 in Drosophila

  2018cites this paper
• Predicting Peroxisomal Targeting Signals to Elucidate the Peroxisomal Proteome of Mammals.

  2018cites this paper
• Peroxisomal monoubiquitinated PEX5 interacts with the AAA ATPases PEX1 and PEX6 and is unfolded during its dislocation into the cytosol

  2018cites this paper
• Peroxisomal Targeting as a Sensitive Tool to Detect Protein-Small RNA Interactions through in Vivo Piggybacking

  2018cites this paper
• Functional characterization of peroxisome biogenic proteins Pex5 and Pex7 of Drosophila

  2018cites this paper
• Prediction of Peroxisomal Matrix Proteins in Plants.

  2018cites this paper
• University of Groningen Functional similarity between the peroxisomal PTS 2 receptor binding protein Pex 18 p and the N-terminal half of the PTS 1 receptor Pex 5

  2017influential citation
• The peroxisomal matrix protein import machinery - a PEX5 - centered perspective

  2017influential citation
• Enzymatic characterization of two acetyl-CoA synthetase genes from Populus trichocarpa

  2016cites this paper
• Characterization, prediction and evolution of plant peroxisomal targeting signals type 1 (PTS1s).

  2016cites this paper
• Peroxisome protein import: a complex journey

  2016cites this paper
• The similarity between N-terminal targeting signals for protein import into different organelles and its evolutionary relevance

  2015cites this paper
• Structural Insights into Cargo Recognition by the Yeast PTS1 Receptor*

  2015cites this paper
• Revisiting the intraperoxisomal pathway of mammalian PEX7

  2015cites this paper
• A pollen-specific calmodulin-binding protein, NPG1, interacts with putative pectate lyases

  2014cites this paper
• Protein Phosphatase 2A Holoenzyme Is Targeted to Peroxisomes by Piggybacking and Positively Affects Peroxisomal β-Oxidation1[OPEN]

  2014cites this paper
• Particle bombardment-mediated transient expression to identify localization signals in plant disease resistance proteins and target sites for the proteolytic activity of pathogen effectors.

  2014cites this paper
• PP2A affects peroxisomal -oxidation

  2014cites this paper
• Proteomic Analysis Reveals That the Rab GTPase RabE1c Is Involved in the Degradation of the Peroxisomal Protein Receptor PEX7 (Peroxin 7)*

  2013cites this paper
• Non-canonical peroxisome targeting signals: identification of novel PTS1 tripeptides and characterization of enhancer elements by computational permutation analysis

  2012cites this paper
• Arabidopsis ABERRANT PEROXISOME MORPHOLOGY9 Is a Peroxin That Recruits the PEX1-PEX6 Complex to Peroxisomes[W]

  2011cites this paper
• Identification of Novel Plant Peroxisomal Targeting Signals by a Combination of Machine Learning Methods and in Vivo Subcellular Targeting Analyses[W]

  2011cites this paper
• An evolutionary study on the role of the PEX11 gene family as a key player in peroxisome proliferation in A. thaliana

  2011cites this paper
• A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum

  2010cites this paper
• Comparison of the peroxisomal matrix protein import system of different organisms. Exploration of possibilities for developing inhibitors of the import system of trypanosomatids for anti-parasite chemotherapy.

  2010cites this paper
• Getting a camel through the eye of a needle: the import of folded proteins by peroxisomes

  2010cites this paper
• In-Depth Proteome Analysis of Arabidopsis Leaf Peroxisomes Combined with in Vivo Subcellular Targeting Verification Indicates Novel Metabolic and Regulatory Functions of Peroxisomes1[W][OA]

  2009cites this paper
• Peroxisome Biogenesis and Function

  2009influential citation
• Mapping the Cargo Protein Membrane Translocation Step into the PEX5 Cycling Pathway*♦

  2009cites this paper
• Diversity in subcellular targeting of the PP2A B′η subfamily members

  2009cites this paper
• Improved prediction of peroxisomal PTS1 proteins from genome sequences based on experimental subcellular targeting analyses as exemplified for protein kinases from Arabidopsis.

  2008influential citation
• Cellular Mechanisms of Gravitropism in ARG1 (Altered Response to Gravity) Mutants of Arabidopsis Thaliana

  2008cites this paper
• MPB2C, a Microtubule-Associated Protein, Regulates Non-Cell-Autonomy of the Homeodomain Protein KNOTTED1[W][OA]

  2007influential citation
• Molecular characterization of the PEX5 gene encoding peroxisomal targeting signal 1 receptor from the methylotrophic yeast Pichia methanolica

  2007cites this paper
• IBR3, a novel peroxisomal acyl-CoA dehydrogenase-like protein required for indole-3-butyric acid response

  2007cites this paper
• Proteome Analysis of Arabidopsis Leaf Peroxisomes Reveals Novel Targeting Peptides, Metabolic Pathways, and Defense Mechanisms[W]

  2007cites this paper
• Molecular and functional characterization of monocot-specific Pex5p splicing variants, using OsPex5pL and OsPex5pS from rice (Oryza sativa).

  2007cites this paper
• Dynamic architecture of the peroxisomal import receptor Pex5p.

  2006cites this paper
• Peroxisome targeting signal 1: is it really a simple tripeptide?

  2006cites this paper
• Cloning of two splice variants of the rice PTS1 receptor, OsPex5pL and OsPex5pS, and their functional characterization using pex5-deficient yeast and Arabidopsis.

  2006cites this paper
• The Arabidopsis pex12 and pex13 mutants are defective in both PTS1- and PTS2-dependent protein transport to peroxisomes.

  2006cites this paper
• Profile and Analysis of Gene Expression Changes during Early Development in Germinating Spores of Ceratopteris richardii1[w]

  2005cites this paper
• A New Type of Peroxisomal Acyl-Coenzyme A Synthetase from Arabidopsis thaliana Has the Catalytic Capacity to Activate Biosynthetic Precursors of Jasmonic Acid*

  2005cites this paper
• Expression profile analysis of early development and gravity response of germinating Ceratopteris richardii spores

  2005cites this paper
• Plant peroxisomes.

  2005cites this paper
• AtLACS7 interacts with the TPR domains of the PTS1 receptor PEX5.

  2005cites this paper
• Specification of the Peroxisome Targeting Signals Type 1 and Type 2 of Plant Peroxisomes by Bioinformatics Analyses1[w]

  2004influential citation
• AraPerox. A Database of Putative Arabidopsis Proteins from Plant Peroxisomes1[w]

  2004cites this paper
• Biogenesis of peroxisomes and glycosomes: trypanosomatid glycosome assembly is a promising new drug target.

  2004cites this paper
• Proteome studies on leaf peroxisomes from Spinacia oleracea L. and Arabidopsis thaliana (L.) Heynh.

  2004cites this paper
• Functional Similarity between the Peroxisomal PTS2 Receptor Binding Protein Pex18p and the N-Terminal Half of the PTS1 Receptor Pex5p

  2004influential citation
• PTS1-independent targeting of isocitrate lyase to peroxisomes requires the PTS1 receptor Pex5p

  2003cites this paper
• Identification of peroxisomal targeting signal of pumpkin catalase and the binding analysis with PTS1 receptor.

  2003cites this paper
• Entering a new era of research on plant peroxisomes.

  2003cites this paper
• Functional differentiation of peroxisomes revealed by expression profiles of peroxisomal genes in Arabidopsis thaliana.

  2003cites this paper
• Correlating structure and affinity for PEX5:PTS1 complexes.

  2003cites this paper
• An in silico assessment of gene function and organization of the phenylpropanoid pathway metabolic networks in Arabidopsis thaliana and limitations thereof.

  2003cites this paper
• Genetic Approaches to Understand Plant Peroxisomes

  2002cites this paper
• Plant Peroxisomes

  2002cites this paper
• Direct interaction and determination of binding domains among peroxisomal import factors in Arabidopsis thaliana.

  2002cites this paper
• STRUCTURE-FUNCTION STUDIES OF THE MAMMALIAN PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2 (MFE-2)

  2002cites this paper
• PEX Genes in Plants and Other Organisms

  2002cites this paper
• Structure-function studies of the mammalian peroxisomal multifunctional enzyme type 2 (MFE-2)

  2002cites this paper
• Targeting and Import of Matrix Proteins into Peroxisomes

  2002cites this paper
• Building new models for peroxisome biogenesis.

  2001cites this paper
• The tetratricopeptide repeat domains of human, tobacco, and nematode PEX5 proteins are functionally interchangeable with the analogous native domain for peroxisomal import of PTS1-terminated proteins in yeast

  2001cites this paper
• Identification and characterisation of PEX6 orthologues from plants.

  2001cites this paper
• Peroxisomal Remnant Structures in Hansenula polymorpha pex5 Cells Can Develop into Normal Peroxisomes upon Induction of the PTS2 Protein Amine Oxidase*

  2001cites this paper
• Sorting of matrix proteins to peroxisomes in the methylotrophic yeast Hansenula polymorpha

  2001cites this paper
• Molecular evolution of the intracellular targeting of alanine glyoxylate aminotransferase.

  2001cites this paper
• The paradox of plastid transit peptides: conservation of function despite divergence in primary structure.

  2001cites this paper
• Peroxisome biogenesis.

  2001cites this paper
• Domain Mapping of Human PEX5 Reveals Functional and Structural Similarities to Saccharomyces cerevisiae Pex18p and Pex21p*

  2001cites this paper
• The Arabidopsis pxa1 mutant is defective in an ATP-binding cassette transporter-like protein required for peroxisomal fatty acid beta-oxidation.

  2001cites this paper
• Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals.

  2001cites this paper
• Tetratricopeptide repeat domain of Yarrowia lipolytica Pex5p is essential for recognition of the type 1 peroxisomal targeting signal but does not confer full biological activity on Pex5p.

  2000cites this paper
• Peroxisome biogenesis and degradation in yeast: A structure/function analysis

  2000cites this paper
• A Pollen-specific Novel Calmodulin-binding Protein with Tetratricopeptide Repeats*

  2000cites this paper
• Genetic analysis of indole-3-butyric acid responses in Arabidopsis thaliana reveals four mutant classes.

  2000cites this paper
• AtPex14p maintains peroxisomal functions by determining protein targeting to three kinds of plant peroxisomes

  2000cites this paper
• Peroxisomal targeting signal-1 receptor protein PEX5 from Leishmania donovani. Molecular, biochemical, and immunocytochemical characterization.

  2000cites this paper
• Plant Peroxisomes: Molecular Basis of the Regulation of their Functions

  2000cites this paper
• Predicting the Function and Subcellular Location of Caenorhabditis Elegans Proteins Similar to Saccharomyces Cerevisiae β-Oxidation Enzymes

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• Peroxisomal Membrane Ascorbate Peroxidase Is Sorted to a Membranous Network That Resembles a Subdomain of the Endoplasmic Reticulum

  1999cites this paper
• Cloning and analysis of the PTS-1 receptor in Trypanosoma brucei.

  1999cites this paper