Cell biology in neuroscience: mechanisms of cell migration in the nervous system.

Many neurons resemble other cells in developing embryos in migrating long distances before they differentiate. However, despite shared basic machinery, neurons differ from other migrating cells. Most dramatically, migrating neurons have a long and dynamic leading process, and may extend an axon from the rear while they migrate. Neurons must coordinate the extension and branching of their leading processes, cell movement with axon specification and extension, switching between actin and microtubule motors, and attachment and recycling of diverse adhesion proteins. New research is needed to fully understand how migration of such morphologically complicated cells is coordinated over space and time.

• Publication year

  2013

• Venue

  Journal of Cell Biology

• Publication date

  2013-09-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201305021PMID 23999166PMCID PMC3760606
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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