Basic fibroblast growth factor-enhanced neurogenesis contributes to cognitive recovery in rats following traumatic brain injury.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Experimental Neurology

• Publication date

  2009-03-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1016/j.expneurol.2008.11.011PMID 19100261PMCID PMC2707259
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• FGF-2-induced functional improvement from neonatal motor cortex injury via corticospinal projections

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• Anatomical integration of newly generated dentate granule neurons following traumatic brain injury in adult rats and its association to cognitive recovery.

  2007influential reference
• Self-Renewing and Differentiating Properties of Cortical Neural Stem Cells Are Selectively Regulated by Basic Fibroblast Growth Factor (FGF) Signaling via Specific FGF Receptors

  2007influential reference
• Enhanced production and dendritic growth of new dentate granule cells in the middle‐aged hippocampus following intracerebroventricular FGF‐2 infusions

  2007cited by this paper
• Characterizing the Mitogenic Effect of Basic Fibroblast Growth Factor in the Adult Rat Striatum

  2006cited by this paper
• Response of the Contralateral Hippocampus to Lateral Fluid Percussion Brain Injury

  2006cited by this paper
• Basic fibroblast growth factor and fibroblast growth factor receptor-1 in the human hippocampal formation.

  2005cited by this paper
• EGF and FGF-2 Infusion Increases Post-Ischemic Neural Progenitor Cell Proliferation in the Adult Rat Brain

  2005cited by this paper
• Cell Proliferation and Neuronal Differentiation in the Dentate Gyrus in Juvenile and Adult Rats following Traumatic Brain Injury

  2005cited by this paper
• Stem/progenitor cell proliferation factors FGF‐2, IGF‐1, and VEGF exhibit early decline during the course of aging in the hippocampus: Role of astrocytes

  2005cited by this paper
• Long‐Term Culture of Hippocampal Neurons

  2004cited by this paper
• Neurogenesis and aging: FGF‐2 and HB‐EGF restore neurogenesis in hippocampus and subventricular zone of aged mice

  2003cited by this paper
• Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice

  2003cited by this paper
• Neuronal and Glial Cell Number in the Hippocampus after Experimental Traumatic Brain Injury: Analysis by Stereological Estimation

  2003cited by this paper
• Short‐term and long‐term survival of new neurons in the rat dentate gyrus

  2003cited by this paper
• FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice.

  2003cited by this paper
• Traumatic Brain Injury Induced Cell Proliferation in the Adult Mammalian Central Nervous System

  2002cited by this paper
• Fibroblast growth factor‐2 increases functional excitatory synapses on hippocampal neurons

  2002cited by this paper
• Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

  2001cited by this paper
• FGF-2 regulation of neurogenesis in adult hippocampus after brain injury

  2001cited by this paper
• Neurobehavioral Assessment of Outcome following Traumatic Brain Injury in Rats: An Evaluation of Selected Measures

  2001cited by this paper
• How to use the optical fractionator: an example based on the estimation of neurons in the hippocampal CA1 and CA3 regions of tree shrews.

  2001cited by this paper
• Enhanced neurogenesis in the rodent hippocampus following traumatic brain injury

  2001cited by this paper
• Evaluation of combined fibroblast growth factor-2 and moderate hypothermia therapy in traumatically brain injured rats.

  2000cited by this paper
• Basic Fibroblast Growth Factor (Fgf2) Is Necessary for Cell Proliferation and Neurogenesis in the Developing Cerebral Cortex

  2000influential reference
• Stimulation of Neonatal and Adult Brain Neurogenesis by Subcutaneous Injection of Basic Fibroblast Growth Factor

  1999cited by this paper
• Basic fibroblast growth factor enhances axonal sprouting after cortical injury in rats.

  1999cited by this paper
• Fibroblast Growth Factor-2 Activates a Latent Neurogenic Program in Neural Stem Cells from Diverse Regions of the Adult CNS

  1999cited by this paper
• Neurotrophin regulation of synaptic transmission.

  1999cited by this paper
• Retrograde signaling in the development and modification of synapses.

  1998cited by this paper
• Experience-Induced Neurogenesis in the Senescent Dentate Gyrus

  1998cited by this paper
• Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

  1997cited by this paper
• FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.

  1997cited by this paper
• In vivo neurogenesis is inhibited by neutralizing antibodies to basic fibroblast growth factor.

  1997cited by this paper
• Delayed Administration of Basic Fibroblast Growth Factor (bFGF) Attenuates Cognitive Dysfunction Following Parasagittal Fluid Percussion Brain Injury in the Rat

  1997cited by this paper
• Regulation of neuronal birth, migration and death in the rat dentate gyrus.

  1996cited by this paper
• Methods for determining numbers of cells and synapses: A case for more uniform standards of review

  1996cited by this paper
• Posttreatment with Intravenous Basic Fibroblast Growth Factor Reduces Histopathological Damage Following Fluid-Percussion Brain Injury in Rats

  1996cited by this paper
• Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor

  1996cited by this paper
• Epidermal Growth Factor and Basic Fibroblast Growth Factor Protect Dopaminergic Neurons from Glutamate Toxicity in Culture

  1995cited by this paper
• Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors.

  1995cited by this paper
• A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain.

  1995cited by this paper
• Intrinsic and extrinsic factors regulating vertebrate neurogenesis.

  1995influential reference
• Characterization of basic fibroblast growth factor-mediated acceleration of axonal branching in cultured rat hippocampal neurons.

  1994cited by this paper
• Histopathologic Consequences of Moderate Concussion in an Animal Model: Correlations with Duration of Unconsciousness

  1994cited by this paper
• Protective effects of basic fibroblast growth factor against hippocampal neuronal damage following cerebral ischemia in the gerbil.

  1993cited by this paper
• Transient increase in endogenous basic fibroblast growth factor in neurons of ischemic rat brains.

  1993cited by this paper
• Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia.

  1993cited by this paper
• In vitro Model of Hypoxia: Basic Fibroblast Growth Factor Can Rescue Cultured CNS Neurons from Oxygen-Deprived Cell Death

  1993cited by this paper
• The proliferation of mature oligodendrocytes in vitro is stimulated by basic fibroblast growth factor and inhibited by oligodendrocyte-type 2 astrocyte precursors.

  1993cited by this paper
• Proliferation, differentiation, and long-term culture of primary hippocampal neurons.

  1993cited by this paper
• Basic fibroblast growth factor protects striatal neurons in vitro from NMDA-receptor mediated excitotoxicity.

  1992cited by this paper
• A time course for the focal elevation of synthesis of basic fibroblast growth factor and one of its high-affinity receptors (flg) following a localized cortical brain injury

  1992cited by this paper
• NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis.

  1991cited by this paper
• Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

  1990cited by this paper
• Fibroblast growth factor (FGF) levels in the developing rat brain.

  1990cited by this paper
• Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

  1965cited by this paper

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  2025cites this paper
• Understanding Folding of bFGF and Potential Cellular Protective Mechanisms of Neural Cells.

  2025cites this paper
• Stem Cell Therapy and Thiamine Deficiency-Induced Brain Damage

  2024cites this paper
• Age-dependent regenerative mechanisms in the brain

  2024cites this paper
• Assessment of the level of apoptosis in differentiated pseudo-neuronal cells derived from neural stem cells under the influence of various inducers.

  2024cites this paper
• Mapping knowledge of the stem cell in traumatic brain injury: a bibliometric and visualized analysis

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• Gliptins normalize posttraumatic hippocampal neurogenesis and restore cognitive function after controlled cortical impact on sensorimotor cortex.

  2023cites this paper
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• Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value

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• Growth factors and their peptide mimetics for treatment of traumatic brain injury.

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• Traumatic Brain Injury: Mechanistic Insight on Pathophysiology and Potential Therapeutic Targets

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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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• Traumatic Brain Injury and Stem Cell: Pathophysiology and Update on Recent Treatment Modalities

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  2017cites this paper
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