The COVID-19 pandemic brought Bioinformatics into the spotlight, revealing that several existing methods, algorithms, and tools were not well prepared to handle large amounts of genomic data efficiently. This led to prohibitively long execution times and the need to reduce the extent of analyses to obtain results in a reasonable amount of time. In this survey, we review available high-performance computing and hardware-accelerated systems based on FPGA and GPU technology. Optimized and hardware-accelerated systems can conduct more thorough analyses considerably faster than pure software implementations, allowing to reach important conclusions in a timely manner to drive scientific discoveries. We discuss the reasons that are currently hindering high-performance solutions from being widely deployed in real-world biological analyses and describe a research direction that can pave the way to enable this.
A Survey of Processing Systems for Phylogenetics and Population Genetics
Reinout Corts,Nikolaos S. Alachiotis
Published 2023 in ACM Transactions on Reconfigurable Technology and Systems
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- Publication year
2023
- Venue
ACM Transactions on Reconfigurable Technology and Systems
- Publication date
2023-03-16
- Fields of study
Biology, Computer Science
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