Genetic architecture of rust resistance in a wheat (Triticum turgidum) diversity panel

Introduction Wheat rust diseases are widespread and affect all wheat growing areas around the globe. Breeding strategies focus on incorporating genetic disease resistance. However, pathogens can quickly evolve and overcome the resistance genes deployed in commercial cultivars, creating a constant need for identifying new sources of resistance. Methods We have assembled a diverse tetraploid wheat panel comprised of 447 accessions of three Triticum turgidum subspecies and performed a genome-wide association study (GWAS) for resistance to wheat stem, stripe, and leaf rusts. The panel was genotyped with the 90K Wheat iSelect single nucleotide polymorphism (SNP) array and subsequent filtering resulted in a set of 6,410 non-redundant SNP markers with known physical positions. Results Population structure and phylogenetic analyses revealed that the diversity panel could be divided into three subpopulations based on phylogenetic/geographic relatedness. Marker-trait associations (MTAs) were detected for two stem rust, two stripe rust and one leaf rust resistance loci. Of them, three MTAs coincide with the known rust resistance genes Sr13, Yr15 and Yr67, while the other two may harbor undescribed resistance genes. Discussion The tetraploid wheat diversity panel, developed and characterized herein, captures wide geographic origins, genetic diversity, and evolutionary history since domestication making it a useful community resource for mapping of other agronomically important traits and for conducting evolutionary studies.

• Publication year

  2023

• Venue

  Frontiers in Plant Science

• Publication date

  2023-03-14

• Fields of study

  Biology, Agricultural and Food Sciences, Medicine

• Identifiers
  DOI 10.3389/fpls.2023.1145371PMID 36998679PMCID 10043469
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Genetic architecture of rust resistance in a wheat (Triticum turgidum) diversity panel

  2023cited by this paper
• Identification and Characterisation of Stripe Rust Resistance Genes Yr66 and Yr67 in Wheat Cultivar VL Gehun 892

  2022cited by this paper
• Genome-Wide Association Study in Bread Wheat Identifies Genomic Regions Associated with Grain Yield and Quality under Contrasting Water Availability

  2022cited by this paper
• Discovery of stripe rust resistance with incomplete dominance in wild emmer wheat using bulked segregant analysis sequencing

  2022cited by this paper
• GWAS for Stripe Rust Resistance in Wild Emmer Wheat (Triticum dicoccoides) Population: Obstacles and Solutions

  2022cited by this paper
• Tandem Protein Kinases Emerge as New Regulators of Plant Immunity

  2021cited by this paper
• GAPIT Version 3: Boosting Power and Accuracy for Genomic Association and Prediction

  2020cited by this paper
• Diversity analysis of 80,000 wheat accessions reveals consequences and opportunities of selection footprints

  2020cited by this paper
• Identification of New Leaf Rust Resistance Loci in Wheat and Wild Relatives by Array-Based SNP Genotyping and Association Genetics

  2020influential reference
• The Global Durum Wheat Panel (GDP): An International Platform to Identify and Exchange Beneficial Alleles

  2020influential reference
• Wheat tandem kinases provide insights on disease-resistance gene flow and host-parasite co-evolution.

  2019influential reference
• The global burden of pathogens and pests on major food crops

  2019cited by this paper
• A large nested association mapping population for breeding and quantitative trait locus mapping in Ethiopian durum wheat

  2019cited by this paper
• Improved Genome Sequence of Wild Emmer Wheat Zavitan with the Aid of Optical Maps

  2019influential reference
• Genome‐Wide Association Study of a Worldwide Collection of Wheat Genotypes Reveals Novel Quantitative Trait Loci for Leaf Rust Resistance

  2019cited by this paper
• Molecular tracking of multiple disease resistance in a winter wheat diversity panel

  2019cited by this paper
• A 3,000-year-old Egyptian emmer wheat genome reveals dispersal and domestication history

  2019cited by this paper
• Pod indehiscence is a domestication and aridity resilience trait in common bean.

  2019cited by this paper
• GWAS for Fusarium Head Blight Traits in a Soft Red Winter Wheat Mapping Panel

  2019cited by this paper
• Durum wheat genome highlights past domestication signatures and future improvement targets

  2019influential reference
• Genome re‐sequencing and simple sequence repeat markers reveal the existence of divergent lineages in the Canadian Puccinia striiformis f. sp. tritici population with extensive DNA methylation

  2018cited by this paper
• Defended to the Nines: 25 Years of Resistance Gene Cloning Identifies Nine Mechanisms for R Protein Function[OPEN]

  2018cited by this paper
• Shifting the limits in wheat research and breeding using a fully annotated reference genome

  2018cited by this paper
• When resistance gene pyramids are not durable-the role of pathogen diversity.

  2018cited by this paper
• Evaluation of Genetic Diversity and Host Resistance to Stem Rust in USDA NSGC Durum Wheat Accessions

  2017cited by this paper
• Introduction: History of Research, Symptoms, Taxonomy of the Pathogen, Host Range, Distribution, and Impact of Stripe Rust

  2017cited by this paper
• Identification and characterization of Sr13, a tetraploid wheat gene that confers resistance to the Ug99 stem rust race group

  2017influential reference
• Yellow Rust Epidemics Worldwide Were Caused by Pathogen Races from Divergent Genetic Lineages

  2017cited by this paper
• Genetic Architecture of Resistance to Stripe Rust in a Global Winter Wheat Germplasm Collection

  2016cited by this paper
• Genome‐Wide Association Mapping of Leaf Rust Response in a Durum Wheat Worldwide Germplasm Collection

  2016cited by this paper
• Comparative Analysis Highlights Variable Genome Content of Wheat Rusts and Divergence of the Mating Loci

  2016cited by this paper
• Genome Wide Association Study of Seedling and Adult Plant Leaf Rust Resistance in Elite Spring Wheat Breeding Lines

  2016cited by this paper
• Stem Rust Resistance in a Geographically Diverse Collection of Spring Wheat Lines Collected from Across Africa

  2016cited by this paper
• Replacement of the European wheat yellow rust population by new races from the centre of diversity in the near-Himalayan region

  2016cited by this paper
• High‐density SNP genotyping array for hexaploid wheat and its secondary and tertiary gene pool

  2015cited by this paper
• A whole-genome shotgun approach for assembling and anchoring the hexaploid bread wheat genome

  2015cited by this paper
• A high-density, SNP-based consensus map of tetraploid wheat as a bridge to integrate durum and bread wheat genomics and breeding.

  2015cited by this paper
• Fitting Linear Mixed-Effects Models Using lme4

  2014cited by this paper
• Efficient Genome-Wide Detection and Cataloging of EMS-Induced Mutations Using Exome Capture and Next-Generation Sequencing[C][W][OPEN]

  2014cited by this paper
• STRUCTURE PLOT: a program for drawing elegant STRUCTURE bar plots in user friendly interface

  2014cited by this paper
• Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array

  2014influential reference
• Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars

  2013cited by this paper
• The interplay between habitat availability and population differentiation

  2012cited by this paper
• Development of High-Density Genetic Maps for Barley and Wheat Using a Novel Two-Enzyme Genotyping-by-Sequencing Approach

  2012cited by this paper
• An efficient multi-locus mixed model approach for genome-wide association studies in structured populations

  2012influential reference
• Nucleotide diversity and linkage disequilibrium in Populus nigra cinnamyl alcohol dehydrogenase (CAD4) gene

  2011cited by this paper
• Genome-wide association studies in plants: the missing heritability is in the field

  2011influential reference
• Geographic distribution and domestication of wild emmer wheat (Triticum dicoccoides)

  2010cited by this paper
• Tracking footprints of maize domestication and evidence for a massive selective sweep on chromosome 10

  2009cited by this paper
• In the Light of Evolution III: Two Centuries of Darwin Sackler Colloquium: Tracking footprints of maize domestication and evidence for a massive selective sweep on chromosome 10

  2009cited by this paper
• Detection of Virulence to Resistance Gene Sr24 Within Race TTKS of Puccinia graminis f. sp. tritici.

  2008cited by this paper
• Status and Prospects of Association Mapping in Plants

  2008cited by this paper
• TASSEL: software for association mapping of complex traits in diverse samples

  2007cited by this paper
• Virulence Phenotypes of a Worldwide Collection of Puccinia triticina from Durum Wheat.

  2007cited by this paper
• The structure of wild and domesticated emmer wheat populations, gene flow between them, and the site of emmer domestication

  2007cited by this paper
• CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure

  2007cited by this paper
• A unified mixed-model method for association mapping that accounts for multiple levels of relatedness

  2006influential reference
• Current status, likely migration and strategies to mitigate the threat to wheat production from race Ug99 (TTKS) of stem rust pathogen

  2006influential reference
• Defining and identifying crop landraces

  2005cited by this paper
• A North American System of Nomenclature for Puccinia coronata f. sp. avenae.

  2000cited by this paper
• Catalogue of gene symbols for wheat: 2000 supplement.

  2000cited by this paper
• Inference of population structure using multilocus genotype data.

  2000cited by this paper
• A rapid and reliable DNA extraction method for higher plants.

  1990cited by this paper
• A North American system of nomenclature for Puccinia recondita f. sp. tritici

  1989cited by this paper
• Variances and covariances of squared linkage disequilibria in finite populations.

  1988cited by this paper
• An international system of nomenclature for Puccinia graminis f.sp. tritici.

  1988cited by this paper
• Identification of physiologic races of Puccinia graminis var. tritici.

  1944cited by this paper

• The transposable elements syndrome of wheat domestication

  2026cites this paper
• Mapping novel yellow and leaf rust loci and predicting resistance in cross derived Canadian durum wheat

  2025cites this paper
• CRISPR-Cas9 based editing of the susceptibility allele TaLr34 enhances leaf rust resistance in bread wheat without yield penalty

  2025cites this paper
• Transferring an Adult-Plant Stripe-Rust Resistance Gene Yr7VS from Chromosome 7V of Dasypyrum villosum (L.) to Bread Wheat

  2024cites this paper
• Broad-spectrum resistance to fungal foliar diseases in wheat: recent efforts and achievements

  2024cites this paper
• The addition of Psathyrostachys Huashanica Keng 6Ns large segment chromosomes has positive impact on stripe rust resistance and plant spikelet number of common wheat

  2024cites this paper
• Future of durum wheat research and breeding: Insights from early career researchers

  2024cites this paper
• Coordinated function of paired NLRs confers Yr84-mediated stripe rust resistance in wheat

  2024cites this paper
• Genetic architecture of rust resistance in a wheat (Triticum turgidum) diversity panel

  2023cites this paper