An extra-circadian function for human CLOCK in the neocortex

No abstract is available for this paper.

• Publication year

  2023

• Venue

  bioRxiv

• Publication date

  2023-03-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/2023.03.13.531623
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Genetic Mechanisms Underlying the Evolution of Connectivity in the Human Cortex

  2022cited by this paper
• Neuronal ambient RNA contamination causes misinterpreted and masked cell types in brain single-nuclei datasets.

  2022cited by this paper
• Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis

  2021cited by this paper
• Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans.

  2021cited by this paper
• A human-specific modifier of cortical connectivity and circuit function

  2021cited by this paper
• Comparative cellular analysis of motor cortex in human, marmoset and mouse

  2021cited by this paper
• NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior.

  2021influential reference
• SNT: a unifying toolbox for quantification of neuronal anatomy

  2020cited by this paper
• Invariant Synapse Density and Neuronal Connectivity Scaling in Primate Neocortical Evolution.

  2020cited by this paper
• A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

  2020cited by this paper
• Expanded encyclopaedias of DNA elements in the human and mouse genomes

  2020cited by this paper
• Integrated analysis of multimodal single-cell data

  2020influential reference
• Effects of repetitive gentle handling of male C57BL/6NCrl mice on comparative behavioural test results

  2020cited by this paper
• Sequence Analysis

  2020cited by this paper
• The evolution of the human brain and disease susceptibility.

  2020cited by this paper
• Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender

  2019cited by this paper
• Philosophical Transactions of the Royal Society B: biological sciences

  2019cited by this paper
• CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency

  2019influential reference
• Single-cell transcriptomic analysis of mouse neocortical development

  2019cited by this paper
• The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development

  2019cited by this paper
• Single-cell genomics identifies cell type–specific molecular changes in autism

  2019influential reference
• CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

  2019cited by this paper
• SpineJ : A software tool for quantitative analysis of nanoscale spine morphology

  2019cited by this paper
• Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains

  2019cited by this paper
• Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons

  2019cited by this paper
• Spatiotemporal transcriptomic divergence across human and macaque brain development

  2018cited by this paper
• Species-Specific Changes in a Primate Transcription Factor Network Provide Insights into the Molecular Evolution of the Primate Prefrontal Cortex

  2018cited by this paper
• CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens

  2018cited by this paper
• The role of CLOCK gene in psychiatric disorders: Evidence from human and animal research

  2018cited by this paper
• Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse.

  2018cited by this paper
• DoubletFinder: Doublet detection in single-cell RNA sequencing data using artificial nearest neighbors

  2018cited by this paper
• Dimensionality reduction for visualizing single-cell data using UMAP

  2018cited by this paper
• Integrating single-cell transcriptomic data across different conditions, technologies, and species

  2018cited by this paper
• Diurnal transcriptome atlas of a primate across major neural and peripheral tissues

  2018cited by this paper
• Human-specific features of spatial gene expression and regulation in eight brain regions

  2018cited by this paper
• Database resources of the National Center for Biotechnology Information

  2017influential reference
• Novel transcriptional networks regulated by CLOCK in human neurons

  2017cited by this paper
• Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy.

  2017influential reference
• Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

  2017cited by this paper
• Spine Dynamics: Are They All the Same?

  2017cited by this paper
• Single-Cell Analysis of Experience-Dependent Transcriptomic States in Mouse Visual Cortex

  2017cited by this paper
• Sumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development.

  2017influential reference
• Foxp1 regulation of neonatal vocalizations via cortical development

  2017cited by this paper
• Transcriptional architecture of the mammalian circadian clock

  2016cited by this paper
• Massively parallel digital transcriptional profiling of single cells

  2016cited by this paper
• Neuronal factors determining high intelligence

  2016cited by this paper
• UMI-tools: Modelling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

  2016influential reference
• Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells.

  2016cited by this paper
• SorCS2 is required for BDNF-dependent plasticity in the hippocampus

  2016cited by this paper
• The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.

  2015influential reference
• Clock genes control cortical critical period timing.

  2015influential reference
• Polymorphism at the Clock gene predicts phenology of long‐distance migration in birds

  2015cited by this paper
• The attentional set shifting task: a measure of cognitive flexibility in mice.

  2015cited by this paper
• Genome engineering using CRISPR-Cas9 system.

  2015influential reference
• Effects of aging on circadian patterns of gene expression in the human prefrontal cortex

  2015cited by this paper
• Circadian clock disruption in neurodegenerative diseases: cause and effect?

  2015cited by this paper
• MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

  2015influential reference
• Behavioral flexibility in rats and mice: contributions of distinct frontocortical regions

  2015cited by this paper
• C57BL/6N mutation in Cytoplasmic FMR interacting protein 2 regulates cocaine response

  2015cited by this paper
• Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation.

  2014cited by this paper
• Evolutionary dynamics of coding and non-coding transcriptomes

  2014cited by this paper
• Long-term electrophysiological activity and pharmacological response of a human induced pluripotent stem cell-derived neuron and astrocyte co-culture.

  2014cited by this paper
• Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness

  2014cited by this paper
• Circadian oscillators in the mouse brain: molecular clock components in the neocortex and cerebellar cortex

  2014cited by this paper
• Neuronal morphometry directly from bitmap images

  2014cited by this paper
• Intracerebroventricular viral injection of the neonatal mouse brain for persistent and widespread neuronal transduction.

  2014cited by this paper
• Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.

  2013cited by this paper
• Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex resembles humans

  2013cited by this paper
• featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

  2013influential reference
• Geography of the circadian gene clock and photoperiodic response in western North American populations of the three-spined stickleback Gasterosteus aculeatus.

  2013cited by this paper
• Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species.

  2013cited by this paper
• Rapid single-step induction of functional neurons from human pluripotent stem cells.

  2013cited by this paper
• Human-specific transcriptional networks in the brain.

  2012influential reference
• Fiji: an open-source platform for biological-image analysis

  2012influential reference
• Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

  2012cited by this paper
• Circadian clock components in the rat neocortex: daily dynamics, localization and regulation

  2012cited by this paper
• Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.

  2012cited by this paper
• Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function.

  2012cited by this paper
• Reversal learning and attentional set-shifting in mice.

  2012cited by this paper
• Spatiotemporal transcriptome of the human brain

  2011cited by this paper
• The novel object recognition memory: neurobiology, test procedure, and its modifications

  2011cited by this paper
• Differential regulation of spontaneous and evoked neurotransmitter release at central synapses.

  2011cited by this paper
• The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms

  2011cited by this paper
• Photic Resetting and Entrainment in CLOCK-Deficient Mice

  2011cited by this paper
• The tail suspension test.

  2011cited by this paper
• Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells

  2010cited by this paper
• Dendritic Growth in Medial Prefrontal Cortex and Cognitive Flexibility Are Enhanced during the Postpartum Period

  2010cited by this paper
• Both Noncoding and Protein-Coding RNAs Contribute to Gene Expression Evolution in the Primate Brain

  2010cited by this paper
• Circadian clock proteins control adaptation to novel environment and memory formation

  2010cited by this paper
• The energetics of genome complexity

  2010cited by this paper
• Human brain evolution: harnessing the genomics (r)evolution to link genes, cognition, and behavior.

  2010cited by this paper
• The Sequence Alignment/Map format and SAMtools

  2009cited by this paper
• ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

  2009cited by this paper
• Membrane Fusion: Grappling with SNARE and SM Proteins

  2009cited by this paper
• Simple Behavioral Assessment of Mouse Olfaction

  2009cited by this paper
• A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice.

  2009cited by this paper
• Human-Specific Transcriptional Regulation of CNS Development Genes by FOXP2

  2009cited by this paper
• Circadian time-place learning in mice depends on Cry genes.

  2008cited by this paper
• Quantification of brain maturation and growth patterns in C57BL/6J mice via computational neuroanatomy of diffusion tensor images.

  2008cited by this paper
• Mania-like behavior induced by disruption of CLOCK

  2007cited by this paper

• Decoding DNA sequence-driven evolution of the human brain epigenome at cellular resolution

  2025cites this paper
• Human-specific genetic modifiers of cortical architecture and function.

  2024cites this paper
• Molecular mechanisms of the specialization of human synapses in the neocortex.

  2024cites this paper