Carnitine determination by an enzymatic cycling method with carnitine dehydrogenase.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Clinical Chemistry

• Publication date

  1994-05-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/CLINCHEM/40.5.817PMID 8174257
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The effect of D,L-carnitine supplementation on muscle metabolism, neuropathy, cardiac and hepatic function in hemodialysis patients. A pilot study.

  2009cited by this paper
• Fluorometric determination of carnitine in serum with immobilized carnitine dehydrogenase and diaphorase.

  1990cited by this paper
• Effect of Deproteinization and Reagent Buffer on the Enzymatic Assay of L-Carnitine in Serum

  1989cited by this paper
• Secondary carnitine deficiency in the newborn period in twins of a mother with partial ornithine transcarbamylase deficiency.

  1989cited by this paper
• Carnitine.

  1988cited by this paper
• Carnitine plasma concentrations in 353 metabolically healthy children

  1988cited by this paper
• Purification and properties of carnitine dehydrogenase from Pseudomonas putida.

  1988cited by this paper
• Secondary carnitine deficiency in hyperammonemic attacks of ornithine transcarbamylase deficiency.

  1988cited by this paper
• Purification and Some Properties of Carnitine Dehydrogenase from Xanthomonas translucens

  1988influential reference
• Carnitine metabolism and function in humans.

  1986cited by this paper
• Serum free carnitine, carnitine esters and lipids in patients on peritoneal dialysis and hemodialysis.

  1986cited by this paper
• Carnitine in human perinatal fat metabolism.

  1985cited by this paper
• Quantitative Bestimmung von l-Carnitin mit Hilfe von Carnitindehydrogenase aus Pseudomonas putida

  1985influential reference
• How important are carnitine and ketones for the newborn infant?

  1985cited by this paper
• Carnitine deficiency, organic acidemias, and Reye's syndrome

  1985cited by this paper
• An improved method for the determination of free and esterified carnitine.

  1985cited by this paper
• Carnitine metabolism and inborn errors

  1984cited by this paper
• Quantitative assessment of carnitine loss during hemodialysis and hemofiltration.

  1983cited by this paper
• Carnitine metabolism and its application in parenteral nutrition.

  1980cited by this paper
• Lipid-lowering effect of carnitine in chronically uremic patients treated with maintenance hemodialysis.

  1980cited by this paper
• Role of carnitine in fatty acid metabolism of normal and ischemic myocardium.

  1979cited by this paper
• [Interrelationships between carnitine metabolism and fatty acid assimilation in Pseudomonas putida (author's transl)].

  1978cited by this paper
• Protection of the ischemic dog myocardium with carnitine.

  1978cited by this paper
• An improved and simplified radioisotopic assay for the determination of free and esterified carnitine.

  1976cited by this paper
• Carnitine Deficiency of Human Skeletal Muscle with Associated Lipid Storage Myopathy: A New Syndrome

  1973cited by this paper
• Distrbution of enzymes between nucleus and cytoplasm of single nerve cell bodies.

  1973cited by this paper
• An enzymatic cycling method for nicotinamide-adenine dinucleotide with malic and alcohol dehydrogenases.

  1973cited by this paper
• A method for the determination of carnitine in the picomole range.

  1972cited by this paper
• Reinigung und Eigenschaften der Carnitindehydrogenase aus Pseudomonas aeruginosa

  1968cited by this paper
• [Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa].

  1968cited by this paper
• ENZYMOLOGICAL DETERMINATION OF FREE CARNITINE CONCENTRATIONS IN RAT TISSUES.

  1964influential reference
• The measurement of pyridine nucleotides by enzymatic cycling.

  1961cited by this paper

• Effects of Atezolizumab plus Bevacizumab on Skeletal Muscle Volume and Cardiac Function in Patients with Hepatocellular Carcinoma

  2024cites this paper
• Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders.

  2024cites this paper
• Low serum carnitine level is associated with increased urinary carnitine excretion in late pregnancy

  2024cites this paper
• Secondary carnitine deficiency during refeeding in severely malnourished patients with eating disorders: a retrospective cohort study

  2024cites this paper
• Pathophysiological roles of the serum acylcarnitine level and acylcarnitine/free carnitine ratio in patients with cardiovascular diseases

  2024cites this paper
• Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders

  2024cites this paper
• Effects of Lenvatinib on Skeletal Muscle Volume and Cardiac Function in Patients with Hepatocellular Carcinoma

  2023cites this paper
• Association of carnitine insufficiency with sarcopenia and dynapenia in patients with heart failure

  2023cites this paper
• Abnormal carnitine metabolism in hemodialysis patients on different anticoagulants

  2023cites this paper
• Validation of target protein PcnWAS in Pomacea canaliculata and screening of target-based molluscicidal compounds.

  2023cites this paper
• Effects of Reducing L-Carnitine Supplementation on Carnitine Kinetics and Cardiac Function in Hemodialysis Patients: A Multicenter, Single-Blind, Placebo-Controlled, Randomized Clinical Trial

  2021cites this paper
• Change in Anemia by Carnitine Supplementation in Patients Undergoing Peritoneal Dialysis: A Retrospective Observational Study

  2021cites this paper
• Relationship between Carnitine Deficiency and Tyrosine Kinase Inhibitor Use in Patients with Chronic Myeloid Leukemia

  2021cites this paper
• Levocarnitine Supplementation Suppresses Lenvatinib-Related Sarcopenia in Hepatocellular Carcinoma Patients: Results of a Propensity Score Analysis

  2021cites this paper
• Carnitine supplementation prevents carnitine deficiency caused by pivalate-conjugated antibiotics in patients with epilepsy prescribed valproate.

  2021cites this paper
• Trimethylamine N‐oxide and outcomes in patients hospitalized with acute heart failure and preserved ejection fraction

  2021cites this paper
• Association between carnitine deficiency and the erythropoietin resistance index in patients undergoing peritoneal dialysis: a cross-sectional observational study

  2020cites this paper
• Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma

  2020cites this paper
• l‐carnitine supplementation vs cycle ergometer exercise for physical activity and muscle status in hemodialysis patients: A randomized clinical trial

  2020cites this paper
• Effects of l-Carnitine Supplementation in Patients Receiving Hemodialysis or Peritoneal Dialysis

  2020cites this paper
• Liver-Oriented Acute Metabolic Effects of A Low Dose of L-Carnitine under Fat-Mobilizing Conditions: Pilot Human Clinical Trial.

  2020cites this paper
• Sorafenib Might Induce Sarcopenia in Patients With Hepatocellular Carcinoma by Inhibiting Carnitine Absorption

  2020cites this paper
• Prevalence of Carnitine Deficiency and Decreased Carnitine Levels in Patients on Hemodialysis

  2019cites this paper
• Spectrophotometric determination of choline in pharmaceutical formulations via host-guest complexation with a biomimetic calixarene receptor

  2019cites this paper
• Carnitine deficiency is associated with decreased exercise activity in hemodialysis patients

  2019cites this paper
• Genome-wide association study of feruloyl arabinoxylan content in common wheat grain

  2019cites this paper
• Serum carnitine levels of children with epilepsy: Related factors including valproate.

  2019cites this paper
• Prevalence of Carnitine Deficiency and Decreased Carnitine Levels in Patients on Peritoneal Dialysis

  2019cites this paper
• 健常者におけるL-カルニチン＋分岐鎖アミノ酸投与後運動負荷のエネルギー代謝･体組成に対する効果に関する基礎的検討

  2018cites this paper
• l-carnitine in critically ill patients—a case series study

  2018cites this paper
• CMOS-compatible biosensor for L-carnitine detection.

  2018cites this paper
• Effects of nine weeks L-Carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress in resistance-trained males

  2018cites this paper
• Risk factors for sodium valproate-induced renal tubular dysfunction

  2018cites this paper
• Plasma L-carnitine levels in terminally ill cancer patients receiving only palliative care.

  2017cites this paper
• Decreased level of serum carnitine might lead to arteriosclerosis progression via the accumulation of advanced glycation end products in maintenance hemodialysis patients

  2017cites this paper
• Screening of carnitine and biotin deficiencies on tandem mass spectrometry

  2017cites this paper
• Dynamics of L-Carnitine in Plasma and Urine in Patients Undergoing Cisplatin Chemotherapy

  2017cites this paper
• Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities

  2017cites this paper
• Carnitine dynamics and their effects on hyperammonemia in cirrhotic Japanese patients

  2017cites this paper
• l‐Carnitine, the Vitamin BT : Uses and Production by the Secondary Metabolism of Bacteria

  2016cites this paper
• Enzymatic cycling method using creatine kinase to measure creatine by real-time detection.

  2016cites this paper
• Levocarnitine Improves Cardiac Function in Hemodialysis Patients With Left Ventricular Hypertrophy: A Randomized Controlled Trial.

  2016cites this paper
• Oral L-Carnitine Supplementation Increases Trimethylamine-N-oxide but Reduces Markers of Vascular Injury in Hemodialysis Patients

  2015cites this paper
• Carnitine in severely disabled patients: relation to anthropometric, biochemical variables, and nutritional intake.

  2015cites this paper
• Carnitine deficiency: Risk factors and incidence in children with epilepsy.

  2015cites this paper
• Effects of intravenous l-carnitine on myocardial fatty acid imaging in hemodialysis patients: responders or non-responders to l-carnitine

  2015cites this paper
• Mutagenesis studies of L-carnitine dehydrogenase for development of biomolecule measurement tool

  2014influential citation
• Alanine-scanning mutation approach for classification of the roles of conserved residues in the activity and substrate affinity of l-carnitine dehydrogenase

  2014cites this paper
• Effects of switching from oral administration to intravenous injection of l-carnitine on lipid metabolism in hemodialysis patients

  2014cites this paper
• Imaging mass spectrometry reveals fiber-specific distribution of acetylcarnitine and contraction-induced carnitine dynamics in rat skeletal muscles.

  2014cites this paper
• Analytical approaches to determination of carnitine in biological materials, foods and dietary supplements.

  2014influential citation
• Carnitine deficiency is associated with late-onset hypogonadism and depression in uremic men with hemodialysis

  2014cites this paper
• Effects of Levocarnitine on Brachial-Ankle Pulse Wave Velocity in Hemodialysis Patients: A Randomized Controlled Trial

  2014cites this paper
• Evidence for a Positive Association Between Serum Carnitine and Free Testosterone Levels in Uremic Men with Hemodialysis

  2013cites this paper
• Identification of Residues Essential for the Activity and Substrate Affinity of l-Carnitine Dehydrogenase

  2013cites this paper
• Potential Inhibitory Effects of l-Carnitine Supplementation on Tissue Advanced Glycation End Products in Patients with Hemodialysis

  2013cites this paper
• Pacing Postconditioning: Impact of Pacing Algorithm, Gender, and Diabetes on Its Myocardial Protective Effects

  2012cites this paper
• Decreased serum carnitine is independently correlated with increased tissue accumulation levels of advanced glycation end products in haemodialysis patients

  2012cites this paper
• An ultrasensitive enzymatic method for measuring mevalonic acid in serum

  2012cites this paper
• Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart.

  2012cites this paper
• L-Carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease

  2012influential citation
• Abnormally low serum acylcarnitine levels in narcolepsy patients.

  2011cites this paper
• A new method for the determination of free l-carnitine in serum samples based on high field single quantum coherence filtering 1H-NMR spectroscopy

  2011cites this paper
• Biochemical Characterization of L-Carnitine Dehydrogenases from Rhizobium sp. and Xanthomonas translucens

  2010cites this paper
• OCTN2 is associated with carnitine transport capacity of rat skeletal muscles

  2010cites this paper
• Potential relationships between transaminase abnormality and valproic acid clearance or serum carnitine concentrations in Japanese epileptic patients

  2008cites this paper
• Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice.

  2008cites this paper
• L-carnitine supplementation decreases the left ventricular mass in patients undergoing hemodialysis.

  2008cites this paper
• Simultaneous quantification of acylcarnitine isomers containing dicarboxylic acylcarnitines in human serum and urine by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

  2007cites this paper
• Effect of Combined Treatment With α‐Lipoic Acid and Acetyl‐L‐Carnitine on Vascular Function and Blood Pressure in Patients With Coronary Artery Disease

  2007cites this paper
• Improvements of hypertriglyceridemia and hyperlacticemia in Japanese children with glycogen storage disease type Ia by medium-chain triglyceride milk

  2007cites this paper
• Acylcarnitine profiles during carnitine loading and fasting tests in a Japanese patient with medium-chain acyl-CoA dehydrogenase deficiency.

  2007cites this paper
• Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease.

  2007cites this paper
• Attenuation of cardiac hypertrophy in carnitine-deficient juvenile visceral steatosis (JVS) mice achieved by lowering dietary lipid.

  2006cites this paper
• Determination of free and total carnitine in plasma by an enzymatic reaction and spectrophotometric quantitation spectrophotometric determination of carnitine.

  2006cites this paper
• Determination of total and free plasma carnitine concentrations on the Dade Behring Dimension RxL: integrated chemistry system.

  2005cites this paper
• Article Molecular and enzymatic properties of 7α-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831

  2004cites this paper
• Kinetic study of the enzymatic cycling reaction conducted with 3alpha-hydroxysteroid dehydrogenase in the presence of excessive thio-NAD(+) and NADH.

  2004cites this paper
• An enzymatic cycling method for the determination of serum total bile acids with recombinant 3alpha-hydroxysteroid dehydrogenase.

  2004cites this paper
• Transient-phase kinetic studies on the nucleotide binding to 3alpha-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831 using fluorescence stopped-flow procedures.

  2004cites this paper
• Steady-state kinetic properties of 3α-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831: Steroid substrate specificity and nucleotide cofactor dependency

  2004cites this paper
• Acylcarnitine Profi les during Carnitine Loading and Fasting Tests in a Japanese Patient with Medium-Chain Acyl-CoA Dehydrogenase Defi ciency

  2003cites this paper
• Effect of L-Carnitine Supplementation on Cardiac Carnitine Palmitoyltransferase Activities and Plasma Carnitine Concentrations in Adriamycin-Treated Rats

  2003cites this paper
• Effect of supplementation with L-carnitine at a small dose on acylcarnitine profiles in serum and urine and the renal handling of acylcarnitines in a patient with multiple acyl-coenzyme A dehydrogenation defect.

  2003cites this paper
• Highly sensitive cholesterol assay with enzymatic cycling applied to measurement of remnant lipoprotein-cholesterol in serum.

  2002cites this paper
• Determination of lactose and D-galactose using thio-NAD+ instead of NAD+

  2002influential citation
• Effect of γ‐butyrobetaine on fatty liver in juvenile visceral steatosis mice

  2001cites this paper
• Verfahren zur bestimmung der konzentration von carnitin in flüssigen substanzen

  2001cites this paper
• Analytical Uses of Enzymes

  2001cites this paper
• Involvement of 1,2-diacylglycerol in improvement of heart function by etomoxir in diabetic rats.

  2001cites this paper
• Effects of food intake and age on the pharmacokinetics of AS-924, a novel ester-type cephem antibiotic. Comparison with cefpodoxime proxetil.

  2001cites this paper
• Effect of gamma-butyrobetaine on fatty liver in juvenile visceral steatosis mice.

  2001cites this paper
• An enzymatic cycling method for the measurement of myo-inositol in biological samples.

  2001cites this paper
• Determination of L-carnitine by flow injection analysis with NADH fluorescence detection.

  2000cites this paper
• Author's Reply

  1999cites this paper
• Pharmacokinetic Analysis of the Cardioprotective Effect of 3-( 2 , 2 , 2-Trimethylhydrazinium ) Propionate in Mice : Inhibition of Carnitine Transport in Kidney 1

  1999cites this paper
• Improvement of Myocardial Fatty Acid Metabolism through L-Carnitine Administration to Chronic Hemodialysis Patients

  1999cites this paper
• Cardiomegaly in the juvenile visceral steatosis (JVS) mouse is reduced with acute elevation of heart short‐chain acyl‐carnitine level after l‐carnitine injection

  1999cites this paper
• Serum carnitine concentrations in patients with idiopathic hypertrophic cardiomyopathy: relationship with impaired myocardial fatty acid metabolism.

  1999cites this paper
• Genetic epidemiology of the carnitine transporter OCTN2 gene in a Japanese population and phenotypic characterization in Japanese pedigrees with primary systemic carnitine deficiency.

  1999cites this paper