Orexin inputs to caudal raphé neurons involved in thermal, cardiovascular, and gastrointestinal regulation

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Histochemistry and Cell Biology

• Publication date

  2005-03-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00418-005-0761-xPMID 15742197
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Distribution of orexin neurons in the adult rat brain

  2007cited by this paper
• Orexin‐A projections to the caudal medulla and orexin‐induced c‐Fos expression, food intake, and autonomic function

  2005influential reference
• Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in rats.

  2004cited by this paper
• Clozapine blocks sympathetic and thermogenic reactions induced by orexin A in rat.

  2004cited by this paper
• Identification of Sympathetic Premotor Neurons in Medullary Raphe Regions Mediating Fever and Other Thermoregulatory Functions

  2004influential reference
• Activation of 5-HT1A receptors in raphe pallidus inhibits leptin-evoked increases in brown adipose tissue thermogenesis.

  2004cited by this paper
• The other side of the orexins: endocrine and metabolic actions.

  2003cited by this paper
• Excitatory Effects of Orexin-A on Nucleus Tractus Solitarius Neurons Are Mediated by Phospholipase C and Protein Kinase C

  2003cited by this paper
• Collateral axonal projections from hypothalamic hypocretin neurons to cardiovascular sites in nucleus ambiguus and nucleus tractus solitarius.

  2003cited by this paper
• Cardioacceleratory responses to hypocretin-1 injections into rostral ventromedial medulla.

  2003influential reference
• Development of Pseudorabies Virus Strains Expressing Red Fluorescent Proteins: New Tools for Multisynaptic Labeling Applications

  2003cited by this paper
• Cardiac effects of hypocretin-1 in nucleus ambiguus.

  2003cited by this paper
• Peptides that regulate food intake: regional, metabolic, and circadian specificity of lateral hypothalamic orexin A feeding stimulation.

  2003cited by this paper
• Raphe pallidus neurons mediate prostaglandin E2-evoked increases in brown adipose tissue thermogenesis.

  2003cited by this paper
• Neurons of the rat preoptic area and the raphe pallidus nucleus innervating the brown adipose tissue express the prostaglandin E receptor subtype EP3

  2003influential reference
• Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure

  2003influential reference
• Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated.

  2002cited by this paper
• Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin.

  2002cited by this paper
• Orexin B immunoreactive fibers and terminals innervate the sensory and motor neurons of jaw‐elevator muscles in the rat

  2002cited by this paper
• Cephalic phase of acid secretion involves activation of medullary TRH receptor subtype 1 in rats.

  2002cited by this paper
• Orexin reverses cholecystokinin‐induced reduction in feeding

  2002cited by this paper
• Activation of Raphe Pallidus Neurons Increases Insulin Through Medullary Thyrotropin-Releasing Hormone (TRH)-Vagal Pathways

  2002cited by this paper
• Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice.

  2002influential reference
• Orexins and appetite regulation.

  2002cited by this paper
• Orexins in rat dorsal motor nucleus of the vagus potently stimulate gastric motor function.

  2002cited by this paper
• Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

  2001cited by this paper
• Mechanisms of orexin‐induced depolarizations in rat dorsal motor nucleus of vagus neurones in vitro

  2001cited by this paper
• Raphe magnus/pallidus neurons regulate tail but not mesenteric arterial blood flow in rats.

  2001cited by this paper
• CSF hypocretin/orexin levels in narcolepsy and other neurological conditions

  2001cited by this paper
• Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord.

  2001cited by this paper
• Orexins: effects on behavior and localisation of orexin receptor 2 messenger ribonucleic acid in the rat brainstem.

  2001cited by this paper
• To eat or to sleep? Orexin in the regulation of feeding and wakefulness.

  2001cited by this paper
• Orexin (Hypocretin) Neurons Contain Dynorphin

  2001cited by this paper
• Hypocretin (orexin) input to trigeminal and hypoglossal motoneurons in the cat: a double-labeling immunohistochemical study.

  2001cited by this paper
• Differential expression of orexin receptors 1 and 2 in the rat brain

  2001cited by this paper
• SB‐334867, a selective orexin‐1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin‐A in rats

  2001influential reference
• Orexin-A Regulates Body Temperature in Coordination with Arousal Status

  2001cited by this paper
• Inhibition of food intake by central injection of anti-orexin antibody in fasted rats.

  2000influential reference
• A selective orexin-1 receptor antagonist reduces food consumption in male and female rats.

  2000influential reference
• Dose-response effects of orexin-A on food intake and the behavioural satiety sequence in rats.

  2000cited by this paper
• CNS origins of the sympathetic nervous system outflow to brown adipose tissue.

  1999influential reference
• GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue.

  1999cited by this paper
• Sympathetic and cardiovascular actions of orexins in conscious rats.

  1999cited by this paper
• Activation of the parapyramidal region in the ventral medulla stimulates gastric acid secretion through vagal pathways in rats.

  1999cited by this paper
• Hypothalamic Hypocretin (Orexin): Robust Innervation of the Spinal Cord

  1999cited by this paper
• Raphe pallidus and parapyramidal neurons regulate ear pinna vascular conductance in the rabbit.

  1999cited by this paper
• Hypothalamic orexin A-immunoreactive neurons project to the rat dorsal medulla.

  1999cited by this paper
• Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat.

  1999cited by this paper
• GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue.

  1999cited by this paper
• Hypothalamic Hypocretin (Orexin): Robust Innervation of the Spinal Cord

  1999cited by this paper
• Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems.

  1999cited by this paper
• Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight.

  1999cited by this paper
• Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action.

  1999cited by this paper
• [Orexins and orexin receptors].

  1999cited by this paper
• Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.

  1999cited by this paper
• Distribution of orexin neurons in the adult rat brain.

  1999cited by this paper
• Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area

  1998cited by this paper
• Hypocretin/Orexin‐ and melanin‐concentrating hormone‐expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene‐related protein systems

  1998cited by this paper
• Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

  1998cited by this paper
• Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

  1998cited by this paper
• Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

  1998cited by this paper
• Caudal raphe-dorsal vagal complex peptidergic projections: role in gastric vagal control.

  1995cited by this paper
• Fos: an immediate-early transcription factor in neurons.

  1995cited by this paper
• TRH in dorsal vagal complex mediates acid response to excitation of raphe pallidus neurons in rats.

  1993cited by this paper
• Pharmacological characterization of muscarinic receptors in neonatal rat cardiomyocytes.

  1993cited by this paper
• c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems.

  1993cited by this paper
• 5-Hydroxytryptamine, substance P and thyrotropin-releasing hormone synapses in the intermediolateral cell column of the rat thoracic spinal cord.

  1992cited by this paper
• Evidence for co-existence of thyrotropin-releasing hormone, substance P and serotonin in ventral medullary neurons that project to the intermediolateral cell column in the rat.

  1990cited by this paper
• Coexistence of varying combinations of neuropeptides with 5-hydroxytryptamine in neurons of the raphe pallidus et obscurus projecting to the spinal cord.

  1989cited by this paper
• Ultrastructural localization of thyrotropin-releasing hormone immunoreactivity in the dorsal vagal complex in rat.

  1989cited by this paper
• The rat brain in stereotaxic coordinates (2nd edn): by George Paxinos and Charles Watson, Academic Press, 1986. £40.00/$80.00 (264 pages) ISBN 012 547 6213

  1987cited by this paper
• Thyrotropin-releasing hormone in spinal cord: coexistence with serotonin and with substance P in fibers and terminals apposing identified preganglionic sympathetic neurons.

  1987influential reference
• Innervation of the nucleus of the solitary tract and the dorsal vagal nucleus by thyrotropin-releasing hormone-containing raphe neurons.

  1986cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper

• Early life stress and hormonal status influence orexin‐1 receptor expression in structures regulating cardiorespiratory responses to CO2

  2025cites this paper
• International Union of Basic and Clinical Pharmacology CXIV: Orexin Receptor Function, Nomenclature and Pharmacology

  2024cites this paper
• Orexin-mediated Motivated Arousal and Reward Seeking.

  2024cites this paper
• Activation of orexin-A (hypocretin-1) receptors in the Raphe Pallidus at different ambient temperatures in the rat: effects on thermoregulation, cardiovascular control, sleep, and feeding behavior

  2024cites this paper
• Progress of autonomic disturbances in narcolepsy type 1

  2023cites this paper
• Peripheral vs. Core Body Temperature as Hypocretin/Orexin Neurons Degenerate: Exercise Mitigates Increased Heat Loss

  2022cites this paper
• A thermoregulatory role of the medullary raphe in birds.

  2021cites this paper
• Centrally Projecting Edinger-Westphal Nucleus in the Control of Sympathetic Outflow and Energy Homeostasis

  2021cites this paper
• Role of the glutamatergic system of ventrolateral periaqueductal gray (vlPAG) in the cardiovascular responses in normal and hemorrhagic conditions in rats

  2021cites this paper
• Melanin‐concentrating hormone‐producing neurons in the hypothalamus regulate brown adipose tissue and thus contribute to energy expenditure

  2021cites this paper
• Central Neural Circuits Orchestrating Thermogenesis, Sleep-Wakefulness States and General Anesthesia States

  2021cites this paper
• A comprehensive review of respiratory, autonomic and cardiovascular responses to intermittent hypoxia in humans

  2021cites this paper
• Circadian Rhythms of the Hypothalamus: From Function to Physiology

  2021cites this paper
• Stimulatory, but not anxiogenic, doses of caffeine act centrally to activate interscapular brown adipose tissue thermogenesis in anesthetized male rats

  2021cites this paper
• Hypothalamic GABRA5-positive Neurons Control Obesity via Astrocytic GABA

  2021cites this paper
• Effects of Caffeine on Brown Adipose Tissue Thermogenesis and Metabolic Homeostasis: A Review

  2021cites this paper
• A subpopulation of Bdnf-e1–expressing glutamatergic neurons in the lateral hypothalamus critical for thermogenesis control

  2019cites this paper
• Obesity: a neuroimmunometabolic perspective

  2019cites this paper
• Pharmacology of Orexin/Hypocretin Receptors

  2019cites this paper
• Thermoregulatory Fear of Harm Mood Disorder: In Depth Exploration of a Unique Juvenile-Onset Phenotype That Provides a Parsimonious Clinical Description of Certain Youths with Highly Comorbid Treatment Refractory Psychiatric Disorders

  2019cites this paper
• Clinical implications of basic research

  2018cites this paper
• Control of Energy Expenditure by AgRP Neurons of the Arcuate Nucleus: Neurocircuitry, Signaling Pathways, and Angiotensin

  2018cites this paper
• Efferent neural pathways for the control of brown adipose tissue thermogenesis and shivering.

  2018cites this paper
• BAT is independently affected by peripheral and central pathways

  2018cites this paper
• The Hypothalamic Preoptic Area and Body Weight Control

  2017cites this paper
• Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway

  2017cites this paper
• Orexin and Central Modulation of Cardiovascular and Respiratory Function.

  2017cites this paper
• REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference

  2017cites this paper
• The Role of Growth Hormone Secretagogue Receptor (GHSR) Signaling in the Dorsomedial Hypothalamus (DMH) and Ventral Premammilary Nucleus (PMV) In Energy Homeostasis in Mice

  2017cites this paper
• Hypothalamus and thermogenesis: Heating the BAT, browning the WAT.

  2016cites this paper
• Contribution of adaptive thermogenesis to the hypothalamic regulation of energy balance.

  2016cites this paper
• Neural Control of Energy Expenditure.

  2016cites this paper
• hypocretinergic system A unified survival theory of the functioning of the

  2015cites this paper
• Absence of TRH receptor 1 in male mice affects gastric ghrelin production.

  2015cites this paper
• Role of the Suprachiasmatic and Arcuate Nuclei in Diurnal Temperature Regulation in the Rat

  2015cites this paper
• Neural circuit for psychological stress-induced hyperthermia

  2015cites this paper
• Orexins (hypocretins) and energy balance: More than feeding.

  2015cites this paper
• Thermoregulation under pressure: a role for orexin neurons

  2015cites this paper
• Reduced brown adipose tissue thermogenesis during environmental interactions in transgenic rats with ataxin-3-mediated ablation of hypothalamic orexin neurons.

  2014cites this paper
• Orexin modulation of adipose tissue.

  2014cites this paper
• Central neural regulation of brown adipose tissue thermogenesis and energy expenditure.

  2014influential citation
• Central nervous system regulation of brown adipose tissue.

  2014influential citation
• Brainstem projections of neurons located in various subdivisions of the dorsolateral hypothalamic area—an anterograde tract-tracing study

  2014cites this paper
• Psychological stress activates a dorsomedial hypothalamus-medullary raphe circuit driving brown adipose tissue thermogenesis and hyperthermia.

  2014cites this paper
• Autonomic regulation of brown adipose tissue thermogenesis in health and disease: potential clinical applications for altering BAT thermogenesis

  2014cites this paper
• Interazione tra Catestatina e fibre Orexinergiche/NMDAergiche in condizioni simil-ischemiche nel criceto ibernante

  2014cites this paper
• Short and long sympathetic-sensory feedback loops in white fat.

  2014cites this paper
• Hypothalamic orexin-A (hypocretin-1) neuronal projections to the vestibular complex and cerebellum in the rat.

  2014cites this paper
• The Brain and Spinal Cord Networks Controlling Locomotion

  2014cites this paper
• The brain and brown fat

  2014cites this paper
• Distribution of Fos-immunoreactive cells in rat forebrain and midbrain following social defeat stress and diazepam treatment.

  2014cites this paper
• Phospholipase Cascades in OX1 Orexin Receptor Signaling

  2014cites this paper
• The Effect of Hindbrain Orexin A Signaling on Brown Adipose Tissue Thermogenesis and Physical Activity

  2014cites this paper
• Orexin A exerts more thermogenic than orexinergic functions

  2014influential citation
• Co-localization of hypocretin-1 and leucine-enkephalin in hypothalamic neurons projecting to the nucleus of the solitary tract and their effect on arterial pressure.

  2013cites this paper
• A unified survival theory of the functioning of the hypocretinergic system.

  2013cites this paper
• Physiology of the orexinergic/hypocretinergic system: a revisit in 2012.

  2013cites this paper
• Orexins Protect Neuronal Cell Cultures Against Hypoxic Stress: an Involvement of Akt Signaling

  2013cites this paper
• Efferent projections of neuropeptide Y‐expressing neurons of the dorsomedial hypothalamus in chronic hyperphagic models

  2013cites this paper
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  2013cites this paper
• The impact of arousal state, sex, and sleep apnea on the magnitude of progressive augmentation and ventilatory long-term facilitation.

  2013cites this paper
• Effects of hypocretin and norepinephrine interaction in bed nucleus of the stria terminalis on arterial pressure.

  2013cites this paper
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  2013cites this paper
• revisit in 2012 Physiology of the orexinergic/hypocretinergic system: a

  2013cites this paper
• Raphe obscurus neurons participate in thermoregulation in rats.

  2013cites this paper
• Orexins, feeding, and energy balance.

  2012cites this paper
• Orexin modulates brown adipose tissue thermogenesis

  2012cites this paper
• Orexin neurons and emotional stress.

  2012influential citation
• Orexin microinjection in the medullary raphe increases heart rate and arterial pressure but does not reduce tail skin blood flow in the awake rat.

  2012cites this paper
• 1 Brain Orexins and Energy Balance 1 . 1 Orexin

  2012cites this paper
• Liver X receptors and fat cell metabolism

  2012cites this paper
• Neuropeptides controlling energy balance: orexins and neuromedins.

  2012cites this paper
• The lateral hypothalamus as integrator of metabolic and environmental needs: from electrical self-stimulation to opto-genetics.

  2011influential citation
• Distribution of orexinergic neurons and their terminal networks in the brains of two species of African mole rats.

  2011cites this paper
• The serotonergic anatomy of the developing human medulla oblongata: implications for pediatric disorders of homeostasis.

  2011cites this paper
• Autonomic disturbances in narcolepsy.

  2011cites this paper
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  2011cites this paper
• Central regulation of autonomic functions

  2011cites this paper
• Panic disorder is associated with the Val308Iso polymorphism in the hypocretin receptor gene

  2011cites this paper
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  2011cites this paper
• The Hypothalamus and Its Functions

  2011cites this paper
• Thyrotropin Releasing Hormone (TRH) in goldfish (Carassius auratus): role in the regulation of feeding and locomotor behaviors and interactions with the orexin system and cocaine- and amphetamine regulated transcript (CART).

  2011cites this paper
• Central Control of Brown Adipose Tissue Thermogenesis

  2011cites this paper
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  2011influential citation
• Innervation of skeletal muscle by leptin receptor-containing neurons.

  2010cites this paper
• Orexin neurons are indispensable for stress‐induced thermogenesis in mice

  2010cites this paper
• Orexin neurons as arousal-associated modulators of central cardiorespiratory regulation.

  2010cites this paper
• Hypothalamic nutrient sensing in the control of energy homeostasis.

  2010cites this paper
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  2010cites this paper
• Potent hyperglycemic and hyperinsulinemic effects of thyrotropin-releasing hormone microinjected into the rostroventrolateral medulla and abnormal responses in type 2 diabetic rats.

  2010cites this paper
• Immunohistochemical localization of orexins (hypocretins) in the brain of reptiles and its relation to monoaminergic systems.

  2010cites this paper
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  2010cites this paper
• Short food deprivation inhibits orexin receptor 1 expression and orexin-A induced intracellular calcium signaling in acutely isolated duodenal enterocytes.

  2009cites this paper
• Neurochemical mechanisms mediating LPS-induced anorexia

  2009cites this paper
• Acute brown adipose tissue temperature response to cold in monosodium glutamate-treated Siberian hamsters.

  2009cites this paper
• Attenuated phrenic long-term facilitation in orexin neuron-ablated mice.

  2009cites this paper
• Orexin-A hyperphagia: hindbrain participation in consummatory feeding responses.

  2009cites this paper
• Hypocretins and primary headaches: neurobiology and clinical implications

  2008cites this paper
• Emotional and state-dependent modification of cardiorespiratory function: role of orexinergic neurons.

  2008cites this paper
• Orexinergic modulation of breathing across vigilance states.

  2008cites this paper