Transition-metal-catalyzed domino reactions of strained bicyclic alkenes

This review presents a comprehensive overview of transition-metal-catalyzed domino reactions of strained bicyclic alkenes, including both homo- and heterobicyclic alkenes. These compounds are important synthons in organic synthesis, providing an important platform for the construction of biologically/medicinally significant compounds which bear multiple stereocenters. The review has been divided according to the metal used in the reaction. An overview of the substrate scope, reaction conditions, and their potential applications in organic synthesis is discussed. A comprehensive outlook on the reactivity paradigms of homo- and heterobicyclic alkenes is discussed and should shed light on future directions for further development in this field.

• Publication year

  2023

• Venue

  Beilstein Journal of Organic Chemistry

• Publication date

  2023-04-24

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.3762/bjoc.19.38PMID 37153643PMCID 10155623
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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