Current Status of Tissue Regenerative Engineering for the Treatment of Uterine Infertility

Dingde Huang,Junhui Liang,Jie Yang,Chunrun Yang,Xin Wang,Tianyu Dai,T. Steinberg,Changzhong Li,Fei Wang

Published 2023 in Tissue engineering. Part B, Reviews

ABSTRACT

With the recent developments in tissue engineering, scientists have attempted to establish seed cells from different sources, create cell sheets through various technologies, implant them on scaffolds with various spatial structures, or load scaffolds with cytokines. These research results are very optimistic, bringing hope to the treatment of patients with uterine infertility. In this article, we reviewed articles related to the treatment of uterine infertility from the aspects of experimental treatment strategy, seed cells, scaffold application, and repair criteria so as to provide a basis for future research. Impact statement Tissue engineering is a new emerging and viable therapeutic method to be contained within repairation of organ injury strategies. So far, there is no review article summarizing and organizing the treatment strategies, application effects, and current research progress of tissue engineering in the treatment of damaged uterine tissue. Therefore, this article focuses on the application of tissue engineering materials, seed cells, and active factors in the repair of uterine injury, aiming to provide theoretical reference for the development of new strategies for treating infertility caused by uterine injury.

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REFERENCES

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