Evi-2, a common integration site involved in murine myeloid leukemogenesis

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Molecular and Cellular Biology

• Publication date

  1990-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.10.9.4658-4666.1990PMID 2167436PMCID PMC361055
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Familial neurofibromatosis and juvenile chronic myelogenous leukemia

  2004cited by this paper
• A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations.

  1990cited by this paper
• Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

  1990cited by this paper
• Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc

  1989cited by this paper
• Immunodeficiency and clonal growth of target cells induced by helper-free defective retrovirus.

  1989cited by this paper
• Activation of the Mlvi-1/mis1/pvt-1 locus in Moloney murine leukemia virus-induced T-cell lymphomas.

  1989cited by this paper
• Recombinant inbred mouse strains: models for studying the molecular genetic basis of myeloid tumorigenesis.

  1989cited by this paper
• Severe immunodeficiency disease induced by a defective murine leukaemia virus

  1989cited by this paper
• A putative int domain for mouse mammary tumor virus on mouse chromosome 7 is a 5' extension of int-2

  1989cited by this paper
• Leucine zipper motif extends

  1989cited by this paper
• A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human.

  1989cited by this paper
• Too many leucine zippers?

  1989cited by this paper
• Leucine-zipper motif update

  1989cited by this paper
• Evidence that the leucine zipper is a coiled coil.

  1989cited by this paper
• Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.

  1989cited by this paper
• The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors.

  1989cited by this paper
• The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.

  1988influential reference
• A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas.

  1988cited by this paper
• Translational activation of the lck proto-oncogene

  1988cited by this paper
• Molecular cloning of a feline leukemia virus that induces fatal immunodeficiency disease in cats.

  1988cited by this paper
• Nucleotide sequence of the first exon of the rat c-myc gene: proviral insertions in murine leukemia virus-induced lymphomas do not affect exon 1.

  1988cited by this paper
• Mouse brain CD4 transcripts encode only the COOH-terminal half of the protein

  1988cited by this paper
• Inactivation of the p53 oncogene by internal deletion or retroviral integration in erythroleukemic cell lines induced by Friend leukemia virus.

  1988cited by this paper
• Identification of a common helper provirus integration site in Abelson murine leukemia virus-induced lymphoma DNA

  1988cited by this paper
• Localization of Evi-2 to chromosome 11: linkage to other proto-oncogene and growth factor loci using interspecific backcross mice.

  1988cited by this paper
• Integration of Friend murine leukemia virus into both alleles of the p53 oncogene in an erythroleukemic cell line

  1988cited by this paper
• C-myc activation in an unusual retrovirus-induced avian T-lymphoma resembling Marek's disease: proviral insertion 5' of exon one enhances the expression of an intron promoter.

  1987cited by this paper
• Insertion and truncation of c-myb by murine leukemia virus in a myeloid cell line derived from cultures of normal hematopoietic cells

  1987cited by this paper
• Common sites of viral integration in lymphomas arising in AKXD recombinant inbred mouse strains.

  1987cited by this paper
• Computer-assisted predictions of signal peptidase processing sites.

  1987cited by this paper
• An aberrant avian leukosis virus provirus inserted downstream from the chicken c-myc coding sequence in a bursal lymphoma results from intrachromosomal recombination between two proviruses and deletion of cellular DNA

  1987cited by this paper
• An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.

  1987cited by this paper
• c-mos proto-oncogene RNA transcripts in mouse tissues: structural features, developmental regulation, and localization in specific cell types

  1987cited by this paper
• Patterns of proviral insertion and deletion in avian leukosis virus-induced lymphomas

  1986cited by this paper
• Two modes of c-myb activation in virus-induced mouse myeloid tumors

  1986cited by this paper
• Expression and structure of the human NGF receptor.

  1986cited by this paper
• Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line.

  1986cited by this paper
• Deregulation of the c-myc oncogene in virus-induced thymic lymphomas of AKR/J mice

  1986cited by this paper
• The activation of cellular oncogenes by retroviral insertion

  1986cited by this paper
• A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation.

  1986cited by this paper
• Chromosome 8 breakpoint far 3′ of the c‐myc oncogene in a Burkitt's lymphoma 2;8 variant translocation is equivalent to the murine pvt‐1 locus.

  1986cited by this paper
• The detection and classification of membrane-spanning proteins.

  1985cited by this paper
• Signal sequences. The limits of variation.

  1985cited by this paper
• Murine T lymphomas with retroviral inserts in the chromosomal 15 locus for plasmacytoma variant translocations

  1985cited by this paper
• Concerted DNA rearrangements in Moloney murine leukemia virus-induced thymomas: a potential synergistic relationship in oncogenesis

  1985cited by this paper
• Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice

  1984cited by this paper
• Proviruses are adjacent to c-myc in some murine leukemia virus-induced lymphomas.

  1984cited by this paper
• Viral integration near c-myc in 10-20% of mcf 247-induced AKR lymphomas.

  1984cited by this paper
• A comprehensive set of sequence analysis programs for the VAX

  1984cited by this paper
• Variant (6 ; 15) translocation in a murine plasmacytoma occurs near an immunoglobulin κ gene but far from the myc oncogene

  1984cited by this paper
• Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

  1984cited by this paper
• Involvement of c‐myc in MuLV‐induced T cell lymphomas in mice: frequency and mechanisms of activation.

  1984cited by this paper
• Computer analysis and structure prediction of nucleic acids and proteins

  1984cited by this paper
• Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2.

  1984cited by this paper
• Genomic sequencing.

  1984cited by this paper
• Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion.

  1984cited by this paper
• A simple method for displaying the hydropathic character of a protein.

  1982cited by this paper
• Ecotropic murine leukemia virus DNA content of normal and lymphomatous tissues of BXH-2 recombinant inbred mice

  1982cited by this paper
• Expression of murine leukemia viruses in the highly lymphomatous BXH-2 recombinant inbred mouse strain

  1981cited by this paper
• Restriction endonuclease mapping of ecotropic murine leukemia viral DNAs: size and sequence heterogeneity of the long terminal repeat.

  1981cited by this paper
• Structure of endogenous murine leukemia virus DNA in mouse genomes.

  1980cited by this paper
• RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination.

  1977cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• NEUROFIBROMATOSIS AND CHILDHOOD LEUKEMIA

  1977cited by this paper
• A clinical, pathological, and genetic study of multiple neurofibromatosis

  1956cited by this paper
• A new method for predkting signal sequence cleavage sites

  year unknowncited by this paper

• Methodological landscape in the field of integration site identification of retroviruses and retroviral vectors

  2025cites this paper
• Exploring potential causal genetic variants and genes for endometrial cancer: Open Targets Genetics, Mendelian randomization, and multi-tissue transcriptome-wide association analysis

  2024cites this paper
• Analysis of scRNA-seq and bulk RNA-seq demonstrates the effects of EVI2B or CD361 on CD8+ T cells in osteosarcoma

  2022cites this paper
• EVI2B Is a New Prognostic Biomarker in Metastatic Melanoma with IFNgamma Associated Immune Infiltration

  2021cites this paper
• Bioinformatics analysis of the key genes in osteosarcoma metastasis and immune invasion

  2021cites this paper
• The Value of Immune-Related Genes Signature in Osteosarcoma Based on Weighted Gene Co-expression Network Analysis

  2021cites this paper
• Insights towards a better understanding and novel treatment modalities of Toxoplasmosis

  2019cites this paper
• A Critical Review of Animal Models Used in Acute Myeloid Leukemia Pathophysiology

  2019cites this paper
• Possible modifier genes in the variation of neurofibromatosis type 1 clinical phenotypes

  2018cites this paper
• A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer.

  2017cites this paper
• EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors

  2017cites this paper
• Cancer Genetics at a Glance: The Comprehensive Insights

  2017cites this paper
• A Combined Omics Approach to Generate the Surface Atlas of Human Naive CD4+ T Cells during Early T-Cell Receptor Activation*

  2015cites this paper
• APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

  2015cites this paper
• to the Septin Gene Family a Putative Proto-Oncogene with Homology SL3-3-Induced T-Cell Lymphomas, Harbors , a Common Integration Site in Sint1

  2014cites this paper
• New Insights into the DT40 B Cell Receptor Cluster Using a Proteomic Proximity Labeling Assay

  2014cites this paper
• Labeling Assay Cluster Using a Proteomic Proximity New Insights into the DT40 B Cell Receptor Immunology

  2014cites this paper
• in myeloid leukemia in BXH-2 mice. Meis1, a PBX1-related homeobox gene involved

  2013cites this paper
• Insertional Mutagenesis for Generating Mouse Models of Cancer

  2012cites this paper
• Insights into NF1 from Evolution

  2012cites this paper
• Dr.VIS: a database of human disease-related viral integration sites

  2011cites this paper
• Overview of Retrovirology

  2010cites this paper
• A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.

  2009cites this paper
• Protein phosphatase regulatory protein 10 cooperates with neurofibromin inactivation in myeloid leukemogenesis

  2008cites this paper
• Cellular and Molecular Biological Studies of a Retroviral Induced Lymphoma, Transmitted via Breast Milk in a Mouse Model

  2008cites this paper
• UNIVERSITY OF FLORIDA THESIS OR DISSERTATION FORMATTING TEMPLATE

  2008influential citation
• Pathogenic risk of endogenous retrovirus infection in immunodeficient hosts.

  2008cites this paper
• Development of a mouse model for the t(10:11)(p13;q14) chromosomal translocation associated with acute leukemia in humans

  2008cites this paper
• Retroviral insertion mutagenesis in mice as a comparative oncogenomics tool to identify disease genes in human leukemia.

  2007cites this paper
• Runx1 Protects Hematopoietic Stem/Progenitor Cells from Oncogenic Insult

  2007cites this paper
• Conditional MLL‐CBP targets GMP and models therapy‐related myeloproliferative disease

  2005cites this paper
• Epigenetic modification as an enabling mechanism for leukemic transformation.

  2005cites this paper
• Animal models of acute myelogenous leukaemia – development, application and future perspectives

  2005cites this paper
• Identification, function and clinical relevance of myeloid leukemia genes

  2005cites this paper
• Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns.

  2004cites this paper
• Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrosses

  2004cites this paper
• A linkage map of mouse Chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation

  2004cites this paper
• Large-Scale Identification of Disease Genes Involved in Acute Myeloid Leukemia

  2004cites this paper
• Homeobox gene expression in normal haemopoiesis and leukaemogenesis.

  2003cites this paper
• Retroviral insertional mutagenesis: tagging cancer pathways.

  2003cites this paper
• A Moloney Murine Leukemia Virus-Based Retrovirus with 4070A Long Terminal Repeat Sequences Induces a High Incidence of Myeloid as Well as Lymphoid Neoplasms

  2003cites this paper
• Transformation and oncogenesis by jaagsiekte sheep retrovirus.

  2003cites this paper
• Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes

  2003cites this paper
• Activation of Clg, a Novel Dbl Family Guanine Nucleotide Exchange Factor Gene, by Proviral Insertion atEvi24, a Common Integration Site in B Cell and Myeloid Leukemias*

  2002cites this paper
• Novel transforming genes in murine myeloid leukemia

  2002cites this paper
• Induction of murine AIDS virus-related sequences after burn injury.

  2002cites this paper
• F-MuLV acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4

  2002cites this paper
• Large-scale identification of novel potential disease loci in mouse leukemia applying an improved strategy for cloning common virus integration sites

  2002cites this paper
• Genetically engineered mouse models of astrocytoma: GEMs in the rough?

  2001cites this paper
• Retroviral Integration at the Epi1Locus Cooperates with Nf1 Gene Loss in the Progression to Acute Myeloid Leukemia

  2001cites this paper
• Distinct gene expression profiling in chronic lymphocytic leukemia with 11q23 deletion

  2001cites this paper
• Activation of the Rap1 Guanine Nucleotide Exchange Gene,CalDAG-GEF I, in BXH-2 Murine Myeloid Leukemia*

  2001cites this paper
• Phenotyping of Evi1, Evi11/Cb2, and Evi12 transformed leukemias isolated from a novel panel of cas-Br-M murine leukemia virus-infected mice.

  2000cites this paper
• Genetic heterogeneity in acute myeloid leukemia: maximizing information flow from MuLV mutagenesis studies

  2000cites this paper
• Sint1, a Common Integration Site in SL3-3-Induced T-Cell Lymphomas, Harbors a Putative Proto-Oncogene with Homology to the Septin Gene Family

  2000cites this paper
• Evi27 encodes a novel membrane protein with homology to the IL17 receptor

  2000cites this paper
• B‐lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays

  2000cites this paper
• Enhancement of erythropoietin-stimulated cell proliferation by Anandamide correlates with increased activation of the mitogen-activated protein kinases ERK1 and ERK2.

  2000cites this paper
• EVI2B, a Gene Lying in an Intron of the Neurofibromatosis Type 1 (NF1) Gene, Is As the NF1 Gene Involved in Differentiation of Melanocytes and Keratinocytes and Is Overexpressed in Cells Derived from NF1 Neurofibromas

  1999cites this paper
• Characterisation of the Fit-1 common integration locus.

  1999cites this paper
• Mrvil, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1

  1999cites this paper
• Retroviral Insertions in Evi12, a Novel Common Virus Integration Site Upstream of Tra1/Grp94, Frequently Coincide with Insertions in the Gene Encoding the Peripheral Cannabinoid Receptor Cnr2

  1999cites this paper
• Oncogene Activation in Myeloid Leukemias by Graffi Murine Leukemia Virus Proviral Integration

  1999cites this paper
• The peripheral cannabinoid receptor, Cb2, in retrovirally-induced leukemic transformation and normal hematopoiesis.

  1998cites this paper
• Contribution of oncogenes and tumor suppressor genes to myeloid leukemia.

  1997cites this paper
• The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11

  1997cites this paper
• Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells.

  1997cites this paper
• The neurofibromatosis type 1 (NF1) tumor suppressor gene and myeloid leukemia.

  1996cites this paper
• Nf1 gene targeting: toward models and mechanisms.

  1996cites this paper
• Molecular genetics of neurofibromatosis type 1 (NF1).

  1996cites this paper
• Molecular analysis of Evi1, a zinc finger oncogene involved in myeloid leukemia.

  1996cites this paper
• Simplified plasmid rescue of host sequences adjacent to integrated proviruses.

  1996cites this paper
• Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

  1996cites this paper
• Retroviral insertional mutagenesis as a strategy to identify cancer genes.

  1996cites this paper
• Nf1 deficiency causes Ras-Dediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

  1996cites this paper
• Mml1, a new common integration site in murine leukemia virus-induced promonocytic leukemias maps to mouse chromosome 10.

  1996cites this paper
• Lissencephaly gene (LIS1) expression in the CNS suggests a role in neuronal migration

  1995cites this paper
• Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice

  1995cites this paper
• The murine AIDS defective provirus acts as an insertional mutagen in its infected target B cells

  1995influential citation
• Neurofibromatosis type 1 and Ras-mediated signaling: filling in the GAPs.

  1995cites this paper
• Epidermal surface antigen (MS17S1) is highly conserved between mouse and human.

  1995cites this paper
• Frequent disruption of the Nf1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas

  1995cites this paper
• Evi-5, a common site of retroviral integration in AKXD T-cell lymphomas, maps near Gfi-1 on mouse chromosome 5

  1995cites this paper
• Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels

  1995influential citation
• PU.1 and an HLH family member contribute to the myeloid‐specific transcription of the Fc gamma RIIIA promoter.

  1994cites this paper
• Deletions spanning the neurofibromatosis 1 gene: identification and phenotype of five patients.

  1994cites this paper
• Identification of Evi-3, a novel common site of retroviral integration in mouse AKXD B-cell lymphomas

  1994cites this paper
• Retroviruses and Their Role in Cancer

  1994cites this paper
• Identification ofEvi-3, aNovelCommonSite ofRetroviral Integration inMouseAKXD B-Cell Lymphomas

  1994cites this paper
• A yeast artificial chromosome contig on mouse chromosome 11 encompassing the nu locus

  1994cites this paper
• Retroviral determinants of leukemogenesis.

  1994cites this paper
• Leukaemogenesis and Lymphomagenesis by Nontransforming Murine Retroviruses

  1993cites this paper
• Expression and DNA rearrangement of proto-oncogenes in Cas-Br-E-induced non-T-, non-B-cell leukemias.

  1993cites this paper
• Induction of antiestrogen resistance in human breast cancer cells by random insertional mutagenesis using defective retroviruses: identification of bcar-1, a common integration site.

  1993cites this paper
• The role of gene mutations in the genesis of familial cancers

  1993cites this paper
• Acute lymphoblastic leukemia in Noonan syndrome: report of two cases.

  1993cites this paper
• Neurofibromatosis type 1 and childhood cancer

  1993cites this paper
• Recombinant inbred mouse strains: models for disease study.

  1992cites this paper
• Hematopoietic transcription regulators and the origins of leukemia.

  1992cites this paper
• A Model for Predicting the Risk of Cancer Consequent to Retroviral Gene Therapy

  1992cites this paper