Identification of the Plasmodium vivax mdr-like gene (pvmdr1) and analysis of single-nucleotide polymorphisms among isolates from different areas of endemicity.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Infectious Diseases

• Publication date

  2005-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1086/426830PMID 15609238
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999cited by this paper
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  1999cited by this paper
• Drug resistant Plasmodium vivax malaria.

  1997cited by this paper
• Diagnosis of resistance to chloroquine by Plasmodium vivax: timing of recurrence and whole blood chloroquine levels.

  1997cited by this paper
• Chloroquine resistant Plasmodium vivax malaria in India

  1996influential reference
• Failure of combined chloroquine and high-dose primaquine therapy for Plasmodium vivax malaria acquired in Guyana, South America.

  1996cited by this paper
• Vivax malaria resistant to chloroquine: case reports from Bombay.

  1995influential reference
• Drug-resistant Plasmodium vivax malaria.

  1994cited by this paper
• Emergence of chloroquine-resistant Plasmodium vivax in Myanmar (Burma).

  1993influential reference
• Chloroquine-resistant Plasmodium vivax from Indonesia.

  1991cited by this paper
• Resistance to chloroquine by Plasmodium vivax in Irian Jaya, Indonesia.

  1991cited by this paper
• Plasmodium vivax resistance to chloroquine?

  1989influential reference
• Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum.

  1989cited by this paper
• Genetic analysis of the human malaria parasite Plasmodium falciparum.

  1987cited by this paper
• Studies on the characterization of plasmodium vivax strains from Central America.

  1972influential reference

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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022influential citation
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