Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  American Journal of Physiology - Cell Physiology

• Publication date

  2003-10-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/AJPCELL.00511.2002PMID 12826604
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Flow-induced expression of endothelial Na-K-Cl cotransport: dependence on K(+) and Cl(-) channels.

  2001cited by this paper
• Endothelial cellular response to altered shear stress.

  2001cited by this paper
• Signaling pathway for nitric oxide generation with simulated ischemia in flow-adapted endothelial cells.

  2001cited by this paper
• Oxidative burst and NO generation as initial response to ischemia in flow-adapted endothelial cells.

  2001cited by this paper
• Tolerance for ATP-Insensitive KATP Channels in Transgenic Mice

  2001cited by this paper
• Vagosympathetic interactions in ischemia-induced myocardial norepinephrine and acetylcholine release.

  2001cited by this paper
• An immediate endothelial cell signaling response to lung ischemia.

  2001cited by this paper
• Ca2+- and Phosphatidylinositol 3-Kinase-dependent Nitric Oxide Generation in Lung Endothelial Cells in Situ with Ischemia*

  2000cited by this paper
• Depolarization-Associated Iron Release with Abrupt Reduction in Pulmonary Endothelial Shear Stress In Situ

  2000cited by this paper
• Control of cAMP in lung endothelial cell phenotypes. Implications for control of barrier function.

  1999cited by this paper
• Control of cAMP in lung endothelial cell phenotypes. Implications for control of barrier function.

  1999cited by this paper
• A flow-activated chloride-selective membrane current in vascular endothelial cells.

  1999cited by this paper
• Simulated ischemia in flow-adapted endothelial cells leads to generation of reactive oxygen species and cell signaling.

  1999cited by this paper
• Responsiveness of vascular endothelium to shear stress: potential role of ion channels and cellular cytoskeleton (review).

  1999cited by this paper
• In Situ Imaging of Intracellular Calcium with Ischemia in Lung Subpleural Microvascular Endothelial Cells

  1999cited by this paper
• The Molecular Assembly of ATP-sensitive Potassium Channels

  1999cited by this paper
• Cloning of the Promoters for the β-Cell ATP-Sensitive K-Channel Subunits Kir6.2 and SUR1

  1998cited by this paper
• Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition.

  1998cited by this paper
• Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force.

  1998cited by this paper
• Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+.

  1998cited by this paper
• ATP-independent membrane depolarization with ischemia in the oxygen-ventilated isolated rat lung.

  1998cited by this paper
• Endothelial gene regulation by laminar shear stress.

  1997cited by this paper
• Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction.

  1997cited by this paper
• Intracellular generation of reactive oxygen species during nonhypoxic lung ischemia.

  1997cited by this paper
• Oxidant generation with K(+)-induced depolarization in the isolated perfused lung.

  1997cited by this paper
• Flow-dependent regulation of gene expression in vascular endothelial cells.

  1996influential reference
• Control of endothelial cell gene expression by flow.

  1995cited by this paper
• Hemodynamic forces are complex regulators of endothelial gene expression

  1995cited by this paper
• An ATP‐sensitive potassium conductance in rabbit arterial endothelial cells.

  1995cited by this paper
• Shear activated channels in cell-attached patches of cultured bovine aortic endothelial cells

  1995cited by this paper
• Flow-mediated endothelial mechanotransduction.

  1995cited by this paper
• Molecular aspects of signal transduction of shear stress in the endothelial cell.

  1994cited by this paper
• Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium.

  1994cited by this paper
• Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells.

  1994cited by this paper
• ATP-sensitive K+ channels in rat aorta and brain microvascular endothelial cells.

  1993cited by this paper
• Haemodynamic shear stress activates a K+ current in vascular endothelial cells

  1988cited by this paper
• The dynamic response of vascular endothelial cells to fluid shear stress.

  1981cited by this paper
• Vascular endothelial morphology as an indicator of the pattern of blood flow.

  1981cited by this paper
• Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

  1981cited by this paper

• Functional expression of inwardly rectifying and ATP‐sensitive potassium channels in human pulmonary artery smooth muscle and endothelial cells

  2026cites this paper
• Flow Sensitive Ion Channels in Vascular Endothelial Cells: Mechanisms of Activation and Roles in Mechanotransduction.

  2025cites this paper
• Panorama of artery endothelial cell dysfunction in pulmonary arterial hypertension.

  2024cites this paper
• Vascular Mechanotransduction.

  2023cites this paper
• Channelopathy Genes in Pulmonary Arterial Hypertension

  2022cites this paper
• Role of Ion Channel Remodeling in Endothelial Dysfunction Induced by Pulmonary Arterial Hypertension

  2022cites this paper
• SUR1 as a New Therapeutic Target for Pulmonary Arterial Hypertension.

  2022cites this paper
• The Effect of a Detraining After Resistance Training on the Histochemical Expression of Potassium Channels and Mitochondrial Biogenesis of Heart Tissue in Male Rats

  2021cites this paper
• Potassium (K+) channels in the pulmonary vasculature: Implications in pulmonary hypertension Physiological, pathophysiological and pharmacological regulation.

  2021cites this paper
• Shear Forces.

  2020cites this paper
• LGM2605 Reduces Space Radiation-Induced NLRP3 Inflammasome Activation and Damage in In Vitro Lung Vascular Networks

  2019cites this paper
• Pulmonary Hypertension and ATP-Sensitive Potassium Channels.

  2019cites this paper
• Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension

  2018cites this paper
• Endothelial Mechanotransduction, Redox Signaling and the Regulation of Vascular Inflammatory Pathways

  2018cites this paper
• Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia

  2018cites this paper
• Ion Channels in Pulmonary Hypertension: A Therapeutic Interest?

  2018cites this paper
• Boosting the signal: Endothelial inward rectifier K+ channels

  2017cites this paper
• Piezo1 Channels in Vascular Development and the Sensing of Shear Stress.

  2017cites this paper
• A microengineered model of RBC transfusion-induced pulmonary vascular injury

  2017cites this paper
• Onset of Inflammation With Ischemia: Implications for Donor Lung Preservation and Transplant Survival

  2016influential citation
• Focusing on Donor Lung Organ Storage: Implications for Inflammation Post-Transplant: Jungraithmayr W et al. signaling with lung transplant

  2016cites this paper
• Endothelial Cell Ion Channel Expression and Function in Arterioles and Resistance Arteries

  2016cites this paper
• Physiological Roles and Cholesterol Sensitivity of Endothelial Inwardly-Rectifying K+ Channels: Specific Cholesterol-Protein Interactions Through Non Annular Binding Sites

  2016cites this paper
• Vascular Endothelial Mechanosensors in Response to Fluid Shear Stress

  2016cites this paper
• Ion Channels in Endothelial Responses to Fluid Shear Stress.

  2016cites this paper
• ATP sensitive potassium channel openers: A new class of ocular hypotensive agents

  2016cites this paper
• Cardiovascular KATP channels and advanced aging

  2016cites this paper
• Reconciling paradigms of abnormal pulmonary blood flow and quasi-malignant cellular alterations in pulmonary arterial hypertension.

  2016cites this paper
• KATP Channels in the Cardiovascular System.

  2016cites this paper
• 1 2 Mechanosignaling in the Vasculature: Emerging Concepts in Sensing, Transduction and Physiological 3

  2015cites this paper
• Mechanosignaling in the vasculature: emerging concepts in sensing, transduction and physiological responses.

  2015cites this paper
• Echinacoside induces rat pulmonary artery vasorelaxation by opening the NO-cGMP-PKG-BKCa channels and reducing intracellular Ca2+ levels

  2015cites this paper
• Ocular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model Systems

  2015cites this paper
• The new antihypertensive drug iptakalim activates ATP-sensitive potassium channels in the endothelium of resistance blood vessels

  2015cites this paper
• Protection of Coronary Endothelial Function during Cardiac Surgery: Potential of Targeting Endothelial Ion Channels in Cardioprotection

  2014influential citation
• S-Glutathionylation of Ion Channels: Insights into the Regulation of Channel Functions, Thiol Modification Crosstalk, and Mechanosensing

  2014cites this paper
• Mechanotransduction Drives Post Ischemic Revascularization Through KATP Channel Closure and Production of Reactive Oxygen Species

  2014cites this paper
• Mechanotransduction in the Endothelium: Role of Membrane Proteins and Reactive Oxygen Species in Sensing, Transduction, and Transmission of the Signal with Altered Blood Flow

  2014influential citation
• Mechanotransduction: Forces, Sensors, and Redox Signaling

  2014cites this paper
• Shear stress-related mechanosignaling with lung ischemia: lessons from basic research can inform lung transplantation.

  2014cites this paper
• PECAM-1 and caveolae form the mechanosensing complex necessary for NOX2 activation and angiogenic signaling with stopped flow in pulmonary endothelium.

  2013influential citation
• Hypoxic pulmonary vasoconstriction.

  2012cites this paper
• Stop the flow: a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endothelium.

  2012influential citation
• Measuring and evaluating the role of ATP-sensitive K+ channels in cardiac muscle.

  2012cites this paper
• Iptakalim rescues human pulmonary artery endothelial cells from hypoxia-induced nitric oxide system dysfunction.

  2012cites this paper
• K(ATP) channel action in vascular tone regulation: from genetics to diseases.

  2012cites this paper
• Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS.

  2012cites this paper
• Transcriptional Remodeling of Ion Channel Subunits by Flow Adaptation in Human Coronary Artery Endothelial Cells

  2011cites this paper
• Effects of Nanoparticles on the Pulmonary Vasculature

  2011cites this paper
• Pulmonary Vascular Mechanobiology

  2011cites this paper
• Shear Stress, Cell Signaling, and Pulmonary Vascular Remodeling

  2011cites this paper
• Acute lung injury and pulmonary vascular permeability: use of transgenic models.

  2011cites this paper
• Pulmonary vascular disease related to hemodynamic stress in the pulmonary circulation.

  2010cites this paper
• KATP Channel Action in Vascular Tone Regulation During Septic Shock: Beyond Physiology

  2009cites this paper
• eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues.

  2009cites this paper
• The effect of glibenclamide on acetylcholine and sodium nitroprusside induced vasodilatation in human cutaneous microcirculation

  2009cites this paper
• Aging, habitual exercise, and vascular ischemia-reperfusion injury

  2009cites this paper
• VENTILATION-INDUCED PULMONARY VASODILATATION IN LAMBS WITH CONGENITAL DIAPHRAGMATIC HERNIA IS MODULATED BY NITRIC OXIDE

  2008cites this paper
• Nicorandil enhances the effect of endothelial nitric oxide under hypoxia-reoxygenation: role of the KATP channel.

  2008cites this paper
• The effect of glibenclamide on cutaneous laser-Doppler flux.

  2008cites this paper
• Ca 2+ - activated K + Channels in Murine Endothelial Cells: Block by Intracellular Calcium and Magnesium

  2008cites this paper
• Forkhead Transcription Factors Coordinate Expression of Myocardial KATP Channel Subunits and Energy Metabolism

  2008cites this paper
• Dissection of two Cx37-independent conducted vasodilator mechanisms by deletion of Cx40: electrotonic versus regenerative conduction.

  2008cites this paper
• Ca2+-activated K+ Channels in Murine Endothelial Cells: Block by Intracellular Calcium and Magnesium

  2008cites this paper
• Caveolae are an essential component of the pathway for endothelial cell signaling associated with abrupt reduction of shear stress.

  2008cites this paper
• Rac and PI3 Kinase Mediate Endothelial Cell–Reactive Oxygen Species Generation During Normoxic Lung Ischemia

  2008influential citation
• Nicorandil enhances the effect of endothelial nitric oxide under hypoxia–reoxygenation: Role of the KATPatp" were changed to "KATP". Please check.--> channel

  2008cites this paper
• Lung Ischemia: A Model for Endothelial Mechanotransduction

  2008cites this paper
• Ion Channels in Shear Stress Sensing in Vascular Endothelium

  2007cites this paper
• Flow-activated ion channels in vascular endothelium

  2007cites this paper
• Secrets of the code: do vascular endothelial cells use ion channels to decipher complex flow signals?

  2006cites this paper
• KATP Channels Are an Important Component of the Shear‐Sensing Mechanism in the Pulmonary Microvasculature

  2006cites this paper
• Role of innate immunity in acetaminophen-induced hepatotoxicity

  2006cites this paper
• Inside Lab Invest

  2006cites this paper
• Role of ATP-Dependent Potassium Channels in Pulmonary Vascular Tone of Fetal Lambs With Congenital Diaphragmatic Hernia

  2006cites this paper
• Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen species.

  2006cites this paper
• The Role of K+ Channels in Determining Pulmonary Vascular Tone, Oxygen Sensing, Cell Proliferation, and Apoptosis: Implications in Hypoxic Pulmonary Vasoconstriction and Pulmonary Arterial Hypertension

  2006cites this paper
• Preconditioning modulates pulmonary endothelial dysfunction following ischemia-reperfusion injury in the rat lung: role of potassium channels.

  2006cites this paper
• The potassium channel opener levcromakalim causes expansive remodelling of experimental vein grafts.

  2006cites this paper
• ATP-Sensitive K+ Channels: Current and Putative Target for the Prevention and Treatment of Cardiovascular Diseases

  2006cites this paper
• Potassium Channels in the Peripheral Microcirculation

  2005cites this paper
• Chapter 10 Heterogeneity of lung endothelial cells

  2005cites this paper
• Activation of endothelial NADPH oxidase during normoxic lung ischemia is KATP channel dependent.

  2005cites this paper
• Nicorandil Inhibits Serum Starvation-Induced Apoptosis in Vascular Endothelial Cells

  2005cites this paper
• Membrane depolarization and NADPH oxidase activation in aortic endothelium during ischemia reflect altered mechanotransduction.

  2005cites this paper
• Reactive Oxygen Species and Cell Signaling in Lung Ischemia

  2005cites this paper
• Ca2+ Flux Through Voltage‐Gated Channels with Flow Cessation in Pulmonary Microvascular Endothelial Cells

  2004cites this paper
• K ATP channels of primary human coronary artery endothelial cells consist of a heteromultimeric complex of Kir6.1, Kir6.2, and SUR2B subunits.

  2004cites this paper
• Endothelial Cell Proliferation Associated with Abrupt Reduction in Shear Stress Is Dependent on Reactive Oxygen Species

  2004influential citation
• Differential membrane potential and ion current responses to different types of shear stress in vascular endothelial cells.

  2004cites this paper
• KATP Channel Activation Induces Ischemic Preconditioning of the Endothelium in Humans In Vivo

  2004cites this paper
• Reactive oxygen species in mechanotransduction.

  2004cites this paper
• The Role of Ischemia-Reperfusion Injury in Graft Rejection

  2004cites this paper
• Shear‐stress preconditioning and tissue‐engineering‐based paradigms for generating arterial substitutes

  2004cites this paper
• Modulation of ATP-sensitive potassium channels by hydrogen sulfide and hydroxylamine

  2004cites this paper
• Shear stress-induced up-regulation of the intermediate-conductance Ca(2+)-activated K(+) channel in human endothelium.

  2003cites this paper